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Biochemical pharmacology, v.78 no.4, 2009년, pp.344 - 354
Cabello, Christopher M. (Department of Pharmacology and Toxicology, College of Pharmacy, Arizona Cancer Center, University of Arizona, 1515 North Campbell Avenue, Tucson, AZ 85724, USA) , Bair 3rd, Warner B. (Department of Pharmacology and Toxicology, College of Pharmacy, Arizona Cancer Center, University of Arizona, 1515 North Campbell Avenue, Tucson, AZ 85724, USA) , Bause 3rd, Alexandra S. (Department of Pharmacology and Toxicology, College of Pharmacy, Arizona Cancer Center, University of Arizona, 1515 North Campbell Avenue, Tucson, AZ 85724, USA) , Wondrak 3rd, Georg T. (Corresponding author. Tel.: +1 520 626 9017)
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Graphical abstract AbstractAltered redox homeostasis involved in the control of cancer cell survival and proliferative signaling represents a chemical vulnerability that can be targeted by prooxidant redox intervention. Here, we demonstrate that the redox dye 2,6-dichlorophenolindophenol (DCPIP) may...
Cancer Res Laurent 65 948 2005 10.1158/0008-5472.948.65.3 Controlling tumor growth by modulating endogenous production of reactive oxygen species
Cancer Chemother Pharmacol Hileman 53 209 2004 10.1007/s00280-003-0726-5 Intrinsic oxidative stress in cancer cells: a biochemical basis for therapeutic selectivity
Curr Opin Investig Drugs Cabello 8 1022 2007 Experimental therapeutics: targeting the redox Achilles heel of cancer
Clin Cancer Res Fruehauf 13 789 2007 10.1158/1078-0432.CCR-06-2082 Reactive oxygen species: a breath of life or death?
Expert Rev Anticancer Ther Fruehauf 8 1751 2008 10.1586/14737140.8.11.1751 Reactive oxygen species: an Achilles’ heel of melanoma?
Drug Resist Update Efferth 8 85 2005 10.1016/j.drup.2005.04.003 Mechanistic perspectives for 1,2,4-trioxanes in anti-cancer therapy
Curr Drug Targets Efferth 7 407 2006 10.2174/138945006776359412 Molecular pharmacology and pharmacogenomics of artemisinin and its derivatives in cancer cells
Biochem Pharmacol Verrax 72 671 2006 10.1016/j.bcp.2006.05.025 Oxidative stress by ascorbate/menadione association kills K562 human chronic myelogenous leukaemia cells and inhibits its tumour growth in nude mice
Cancer Res Loewe 66 11888 2006 10.1158/0008-5472.CAN-06-2397 Dimethylfumarate impairs melanoma growth and metastasis
Cancer Lett Wang 259 82 2008 10.1016/j.canlet.2007.10.005 Plumbagin induces cell cycle arrest and apoptosis through reactive oxygen species/c-Jun N-terminal kinase pathways in human melanoma A375.S2 cells
Free Radic Biol Med Cabello 46 220 2009 10.1016/j.freeradbiomed.2008.10.025 The cinnamon-derived Michael acceptor cinnamic aldehyde impairs melanoma cell proliferation, invasiveness, and tumor growth
Org Biomol Chem Fry 3 2579 2005 10.1039/b502197a Multifunctional redox catalysts as selective enhancers of oxidative stress
Semin Cancer Biol Magda 16 466 2006 10.1016/j.semcancer.2006.09.002 Motexafin gadolinium: a novel redox active drug for cancer therapy
Free Radic Biol Med Wondrak 43 178 2007 10.1016/j.freeradbiomed.2007.03.035 NQO1-activated phenothiazinium redox cyclers for the targeted bioreductive induction of cancer cell apoptosis
Oncol Rep Berger 14 1599 2005 Artesunate in the treatment of metastatic uveal melanoma-first experiences
J Med Chem Cen 47 6914 2004 10.1021/jm049568z Disulfiram facilitates intracellular Cu uptake and induces apoptosis in human melanoma cells
Mol Cancer Ther Kirshner 7 2319 2008 10.1158/1535-7163.MCT-08-0298 Elesclomol induces cancer cell apoptosis through oxidative stress
J Natl Cancer Inst Tuma 100 11 2008 10.1093/jnci/djm299 Reactive oxygen species may have antitumor activity in metastatic melanoma
Am J Physiol Cell Physiol Brar 282 C1212 2002 10.1152/ajpcell.00496.2001 An NAD(P)H oxidase regulates growth and transcription in melanoma cells
Melanoma Res Wittgen 17 400 2007 10.1097/CMR.0b013e3282f1d312 Reactive oxygen species in melanoma and its therapeutic implications
Pigment Cell Melanoma Res Fried 21 117 2008 10.1111/j.1755-148X.2008.00451.x The reactive oxygen-driven tumor: relevance to melanoma
J Biol Chem Criddle 281 40485 2006 10.1074/jbc.M607704200 Menadione-induced reactive oxygen species generation via redox cycling promotes apoptosis of murine pancreatic acinar cells
Methods Enzymol Ernster 10 309 1967 10.1016/0076-6879(67)10059-1 DT-diaphorase
Methods Enzymol Wilson 54 396 1978 10.1016/S0076-6879(78)54025-1 Determination of oxidation-reduction potentials
Clin Chem VanderJagt 32 1004 1986 10.1093/clinchem/32.6.1004 Ascorbate in plasma as measured by liquid chromatography and by dichlorophenolindophenol colorimetry
Plant Physiol Yamashita 43 1978 1968 10.1104/pp.43.12.1978 Photoreduction and photophosphorylation with tris-washed chloroplasts
Biochim Biophys Acta Mayer 1015 258 1990 10.1016/0005-2728(90)90029-4 Investigation by amperometric methods of intracellular reduction of 2,6-dichlorophenolindophenol in normal and transformed hepatocytes in the presence of different inhibitors of cellular metabolism
Anal Biochem Kumar 268 89 1999 10.1006/abio.1998.3009 2,6-Dichloro-phenol indophenol prevents switch-over of electrons between the cyanide-sensitive and -insensitive pathway of the mitochondrial electron transport chain in the presence of inhibitors
Melanoma Res Wolchok 13 189 2003 10.1097/00008390-200304000-00013 Phase I trial of high dose paracetamol and carmustine in patients with metastatic melanoma
J Pharm Sci Vad 98 1409 2009 10.1002/jps.21505 Biochemical mechanism of acetaminophen (APAP) induced toxicity in melanoma cell lines
MSDS: 2,6-Dichloroindophenol sodium salt (CAS#620-45-1). Sigma-Aldrich Version 1.5, 01/31/2006.
J Pharmacol Exp Ther Wondrak 316 805 2006 10.1124/jpet.105.094953 Antimelanoma activity of apoptogenic carbonyl scavengers
Methods Enzymol Ross 382 115 2004 10.1016/S0076-6879(04)82008-1 NAD(P)H:quinone oxidoreductase 1 (NQO1, DT-diaphorase), functions and pharmacogenetics
Toxicol In Vitro Baigi 22 1547 2008 10.1016/j.tiv.2008.06.008 Apoptosis/necrosis switch in two different cancer cell lines: influence of benzoquinone- and hydrogen peroxide-induced oxidative stress intensity, and glutathione
Cancer Res Fukuyo 68 6324 2008 10.1158/0008-5472.CAN-07-6602 Oxidative stress plays a critical role in inactivating mutant BRAF by geldanamycin derivatives
Exp Cell Res Noonan 314 2468 2008 10.1016/j.yexcr.2008.05.002 Hsp70B’ and Hsp72 form a complex in stressed human colon cells and each contributes to cytoprotection
Cancer Gene Ther Baron 13 115 2006 10.1038/sj.cgt.7700896 The transcription factor Egr1 is a direct regulator of multiple tumor suppressors including TGFbeta1, PTEN, p53, and fibronectin
Cancer Biol Ther Shen 7 1407 2008 10.4161/cbt.7.9.6429 Platinums sensitize human epithelial tumor cells to lymphotoxin alpha by inhibiting NFkappaB-dependent transcription
Proc Natl Acad Sci USA Sarkar 99 10054 2002 10.1073/pnas.152327199 mda-7 (IL-24) Mediates selective apoptosis in human melanoma cells by inducing the coordinated overexpression of the GADD family of genes by means of p38 MAPK
Carcinogenesis Scott 25 2155 2004 10.1093/carcin/bgh239 Curcumin-induced GADD153 gene up-regulation in human colon cancer cells
Cell Stress Chaperones Chow 12 237 2007 10.1379/CSC-269.1 Induction of heat shock proteins in differentiated human and rodent neurons by celastrol
Curr Cancer Ther Rev Wondrak 1 271 2005 10.2174/157339405774574234 An emerging molecular target in melanoma: cellular carbonyl stress and the inhibition of mitochondrial survival pathways by carbonyl scavenger agents
J Invest Dermatol Hocker 128 2575 2008 10.1038/jid.2008.226 Melanoma genetics and therapeutic approaches in the 21st century: moving from the benchside to the bedside
Physiol Genomics Han 2008 10.1152/physiolgenomics.00239.2007 The in vivo gene expression signature of oxidative stress
Cancer Chemother Pharmacol Paine-Murrieta 40 209 1997 10.1007/s002800050648 Human tumor models in the severe combined immune deficient (scid) mouse
J Biol Chem Abdelmohsen 278 38360 2003 10.1074/jbc.M306785200 Epidermal growth factor receptor is a common mediator of quinone-induced signaling leading to phosphorylation of connexin-43: role of glutathione and tyrosine phosphatases
Toxicol Sci Schmieder 72 66 2003 10.1093/toxsci/kfg016 Discriminating redox cycling and arylation pathways of reactive chemical toxicity in trout hepatocytes
Mol Pharmacol Lau 34 829 1988 Sequential oxidation and glutathione addition to 1,4-benzoquinone: correlation of toxicity with increased glutathione substitution
Chem Res Toxicol Bratton 13 550 2000 10.1021/tx0000015 The putative benzene metabolite 2,3, 5-tris(glutathion-S-yl)hydroquinone depletes glutathione, stimulates sphingomyelin turnover, and induces apoptosis in HL-60 cells
J Biol Chem Hadler 241 2886 1966 10.1016/S0021-9258(18)96547-6 Conjugation of 2,6-dichloroindophenol with mitochondrial thiol groups
Anal Biochem Dupuy 191 16 1990 10.1016/0003-2697(90)90379-N Nonenzymatic NADPH-dependent reduction of 2,6-dichlorophenol-indophenol
Cancer Res Sharp 67 2206 2007 10.1158/0008-5472.CAN-06-3473 In vitro biological characterization of a novel, synthetic diaryl pyrazole resorcinol class of heat shock protein 90 inhibitors
Curr Eye Res Wilson 22 348 2001 10.1076/ceyr.22.5.348.5495 Immunohistochemical localization of NAD(P)H:quinone oxidoreductase in conjunctival melanomas and primary acquired melanosis
Cancer Treat Rev Danson 30 437 2004 10.1016/j.ctrv.2004.01.002 DT-diaphorase: a target for new anticancer drugs
Mol Carcinog Lewis 43 215 2005 10.1002/mc.20107 Targeting NAD(P)H:quinone oxidoreductase (NQO1) in pancreatic cancer
Oncogene Seng 28 378 2009 10.1038/onc.2008.396 NRP/B mutations impair Nrf2-dependent NQO1 induction in human primary brain tumors
Cancer Res Wiemels 59 4095 1999 A lack of a functional NAD(P)H:quinone oxidoreductase allele is selectively associated with pediatric leukemias that have MLL fusions. United Kingdom Childhood Cancer Study Investigators
Biofactors Bruge 32 71 2008 10.1002/biof.5520320109 NAD(P)H:quinone oxidoreductase (NQO1) loss of function in Burkitt's lymphoma cell lines
Nat Genet Fagerholm 40 844 2008 10.1038/ng.155 NAD(P)H:quinone oxidoreductase 1 NQO1*2 genotype (P187S) is a strong prognostic and predictive factor in breast cancer
Bioorg Med Chem Lett Nolan 16 6246 2006 10.1016/j.bmcl.2006.09.015 In silico identification and biochemical characterization of novel inhibitors of NQO1
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