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NTIS 바로가기Nature reviews. Drug discovery, v.8 no.8, 2009년, pp.627 - 644
Liu, Pixu (Departments of Cancer Biology, Dana–) , Cheng, Hailing (Farber Cancer Institute, Pathology, Harvard Medical School, Boston, Massachusetts 02115, USA.) , Roberts, Thomas M. (Departments of Cancer Biology, Dana–) , Zhao, Jean J. (Farber Cancer Institute, Pathology, Harvard Medical School, Boston, Massachusetts 02115, USA.)
The phosphoinositide 3-kinase (PI3K) pathway is a key signal transduction system that links oncogenes and multiple receptor classes to many essential cellular functions, and is perhaps the most commonly activated signalling pathway in human cancer. This pathway therefore presents both an opportunity...
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