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NTIS 바로가기BMC genetics, v.10, 2009년, pp.12 - 12
Boles, Melissa K (Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA) , Wilkinson, Bonney M (Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA) , Maxwell, Andrea (Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA) , Lai, Lihua (Departments of Pediatrics and of Molecular and Cellular Biology, Center for Cell and Gene Therapy, Children's Nutrition Research Center, Baylor College of Medicine, Houston, TX 77030, USA) , Mills, Alea A (Cold Spring Harbor Laboratory, Cold Spring Harbor, NY 11724, USA) , Nishijima, Ichiko (Center for Molecular and Human Genetics, Columbus Children's Research Institute, The Ohio State University, Columbus, OH 43205, USA) , Salinger, Andrew P (Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA) , Moskowitz, Ivan (Departments of Pediatrics and Pathology, Institute for Molecular Pediatric Sciences, The University of Chicago, Chicago, IL 60637, USA) , Hirschi, Karen K (Departments of Pediatrics and of Molecular and Cellular Biology, Center for Cell and) , Liu, Bin , Bradley, Allan , Justice, Monica J
BackgroundENU-mutagenesis is a powerful technique to identify genes regulating mammalian development. To functionally annotate the distal region of mouse chromosome 4, we performed an ENU-mutagenesis screen using a balancer chromosome targeted to this region of the genome.ResultsWe isolated 11 letha...
Acevedo-Arozena A Wells S Potter P Kelly M Cox RD Brown SD ENU Mutagenesis, a Way Forward to Understand Gene Function Annu Rev Genomics Hum Genet 2008 9 49 69 18949851 10.1146/annurev.genom.9.081307.164224
Nishijima I Mills A Qi Y Mills M Bradley A Two new balancer chromosomes on mouse chromosome 4 to facilitate functional annotation of human chromosome 1p Genesis 2003 36 142 148 12872245 10.1002/gene.10207
Zheng B Sage M Cai WW Thompson DM Tavsanli BC Cheah YC Bradley A Engineering a mouse balancer chromosome Nat Genet 1999 22 375 378 10431243 10.1038/11949
Hentges KE Nakamura H Furuta Y Yu Y Thompson DM O'Brien W Bradley A Justice MJ Novel lethal mouse mutants produced in balancer chromosome screens Gene Expr Patterns 2006 6 653 665 16466971 10.1016/j.modgep.2005.11.015
Kile BT Hentges KE Clark AT Nakamura H Salinger AP Liu B Box N Stockton DW Johnson RL Behringer RR Bradley A Justice MJ Functional genetic analysis of mouse chromosome 11 Nature 2003 425 81 86 12955145 10.1038/nature01865
Hentges KE Justice MJ Checks and balancers: balancer chromosomes to facilitate genome annotation Trends Genet 2004 20 252 259 15145578 10.1016/j.tig.2004.04.004
Ohtoshi A Bradley A Behringer RR Nishijima I Generation and maintenance of Dmbx1 gene-targeted mutant alleles Mamm Genome 2006 17 744 750 16845469 10.1007/s00335-006-0021-y
Yamanaka Y Heike T Kumada T Shibata M Takaoka Y Kitano A Shiraishi K Kato T Nagato M Okawa K Furushima K Nakao K Nakamura Y Taketo MM Aizawa S Nakahata T Loss of Borealin/DasraB leads to defective cell proliferation, p53 accumulation and early embryonic lethality Mech Dev 2008 125 441 450 18337066 10.1016/j.mod.2008.01.011
Shivdasani RA Mayer EL Orkin SH Absence of blood formation in mice lacking the T-cell leukaemia oncoprotein tal-1/SCL Nature 1995 373 432 434 7830794 10.1038/373432a0
Andrade N Komnenovic V Blake SM Jossin Y Howell B Goffinet A Schneider WJ Nimpf J ApoER2/VLDL receptor and Dab1 in the rostral migratory stream function in postnatal neuronal migration independently of Reelin Proc Natl Acad Sci USA 2007 104 8508 8513 17494763 10.1073/pnas.0611391104
Borrell V Pujadas L Simo S Dura D Sole M Cooper JA Del Rio JA Soriano E Reelin and mDab1 regulate the development of hippocampal connections Mol Cell Neurosci 2007 36 158 173 17720534 10.1016/j.mcn.2007.06.006
Adham IM Khulan J Held T Schmidt B Meyer BI Meinhardt A Engel W Fas-associated factor (FAF1) is required for the early cleavage-stages of mouse embryo Mol Hum Reprod 2008 14 207 213 18303090 10.1093/molehr/gan009
Richardson RT Alekseev OM Grossman G Widgren EE Thresher R Wagner EJ Sullivan KD Marzluff WF O'Rand MG Nuclear autoantigenic sperm protein (NASP), a linker histone chaperone that is required for cell proliferation J Biol Chem 2006 281 21526 21534 16728391 10.1074/jbc.M603816200
Hanna LA Foreman RK Tarasenko IA Kessler DS Labosky PA Requirement for Foxd3 in maintaining pluripotent cells of the early mouse embryo Genes Dev 2002 16 2650 2661 12381664 10.1101/gad.1020502
Plum A Winterhager E Pesch J Lautermann J Hallas G Rosentreter B Traub O Herberhold C Willecke K Connexin31-deficiency in mice causes transient placental dysmorphogenesis but does not impair hearing and skin differentiation Dev Biol 2001 231 334 347 11237463 10.1006/dbio.2000.0148
Schnichels M Worsdorfer P Dobrowolski R Markopoulos C Kretz M Schwarz G Winterhager E Willecke K The connexin31 F137L mutant mouse as a model for the human skin disease erythrokeratodermia variabilis (EKV) Hum Mol Genet 2007 16 1216 1224 17446259 10.1093/hmg/ddm068
Montgomery RL Davis CA Potthoff MJ Haberland M Fielitz J Qi X Hill JA Richardson JA Olson EN Histone deacetylases 1 and 2 redundantly regulate cardiac morphogenesis, growth, and contractility Genes Dev 2007 21 1790 1802 17639084 10.1101/gad.1563807
Lagger G O'Carroll D Rembold M Khier H Tischler J Weitzer G Schuettengruber B Hauser C Brunmeir R Jenuwein T Seiser C Essential function of histone deacetylase 1 in proliferation control and CDK inhibitor repression Embo J 2002 21 2672 2681 12032080 10.1093/emboj/21.11.2672
Chen HJ Lin CM Lin CS Perez-Olle R Leung CL Liem RK The role of microtubule actin cross-linking factor 1 (MACF1) in the Wnt signaling pathway Genes Dev 2006 20 1933 1945 16815997 10.1101/gad.1411206
Mochizuki R Dateki M Yanai K Ishizuka Y Amizuka N Kawashima H Koga Y Ozawa H Fukamizu A Targeted disruption of the neurochondrin/norbin gene results in embryonic lethality Biochem Biophys Res Commun 2003 310 1219 1226 14559245 10.1016/j.bbrc.2003.09.153
Phillips JD Jackson LK Bunting M Franklin MR Thomas KR Levy JE Andrews NC Kushner JP A mouse model of familial porphyria cutanea tarda Proc Natl Acad Sci USA 2001 98 259 264 11134514 10.1073/pnas.011481398
Ying Y Liu XM Marble A Lawson KA Zhao GQ Requirement of Bmp8b for the generation of primordial germ cells in the mouse Mol Endocrinol 2000 14 1053 1063 10894154 10.1210/me.14.7.1053
Escalante-Alcalde D Hernandez L Le Stunff H Maeda R Lee HS Gang C Jr Sciorra VA Daar I Spiegel S Morris AJ Stewart CL The lipid phosphatase LPP3 regulates extra-embryonic vasculogenesis and axis patterning Development 2003 130 4623 4637 12925589 10.1242/dev.00635
Escalante-Alcalde D Sanchez-Sanchez R Stewart CL Generation of a conditional Ppap2b/Lpp3 null allele Genesis 2007 45 465 469 17610274 10.1002/dvg.20314
Wang D Pascual JM Yang H Engelstad K Mao X Cheng J Yoo J Noebels JL De Vivo DC A mouse model for Glut-1 haploinsufficiency Hum Mol Genet 2006 15 1169 1179 16497725 10.1093/hmg/ddl032
Izraeli S Lowe LA Bertness VL Good DJ Dorward DW Kirsch IR Kuehn MR The SIL gene is required for mouse embryonic axial development and left-right specification Nature 1999 399 691 694 10385121 10.1038/21429
Wechsler A Brafman A Shafir M Heverin M Gottlieb H Damari G Gozlan-Kelner S Spivak I Moshkin O Fridman E Becker Y Skaliter R Einat P Faerman A Bjorkhem I Feinstein E Generation of viable cholesterol-free mice Science 2003 302 2087 14684813 10.1126/science.1090776
Zheng-Fischhofer Q Kibschull M Schnichels M Kretz M Petrasch-Parwez E Strotmann J Reucher H Lynn BD Nagy JI Lye SJ Winterhager E Willecke K Characterization of connexin31.1-deficient mice reveals impaired placental development Dev Biol 2007 312 258 271 17961533 10.1016/j.ydbio.2007.09.025
Wu M Chen DF Sasaoka T Tonegawa S Neural tube defects and abnormal brain development in F52-deficient mice Proc Natl Acad Sci USA 1996 93 2110 2115 8700893 10.1073/pnas.93.5.2110
Gunes C Heuchel R Georgiev O Muller KH Lichtlen P Bluthmann H Marino S Aguzzi A Schaffner W Embryonic lethality and liver degeneration in mice lacking the metal-responsive transcriptional activator MTF-1 Embo J 1998 17 2846 2854 9582278 10.1093/emboj/17.10.2846
Enkhmandakh B Makeyev AV Bayarsaihan D The role of the proline-rich domain of Ssdp1 in the modular architecture of the vertebrate head organizer Proc Natl Acad Sci USA 2006 103 11631 11636 16864769 10.1073/pnas.0605209103
Sato TN Tozawa Y Deutsch U Wolburg-Buchholz K Fujiwara Y Gendron-Maguire M Gridley T Wolburg H Risau W Qin Y Distinct roles of the receptor tyrosine kinases Tie-1 and Tie-2 in blood vessel formation Nature 1995 376 70 74 7596437 10.1038/376070a0
Lu ZH Books JT Ley TJ YB-1 is important for late-stage embryonic development, optimal cellular stress responses, and the prevention of premature senescence Mol Cell Biol 2005 25 4625 4637 15899865 10.1128/MCB.25.11.4625-4637.2005
Rodig SJ Meraz MA White JM Lampe PA Riley JK Arthur CD King KL Sheehan KC Yin L Pennica D Johnson EM Jr Schreiber RD Disruption of the Jak1 gene demonstrates obligatory and nonredundant roles of the Jaks in cytokine-induced biologic responses Cell 1998 93 373 383 9590172 10.1016/S0092-8674(00)81166-6
Richard S Torabi N Franco GV Tremblay GA Chen T Vogel G Morel M Cleroux P Forget-Richard A Komarova S Tremblay ML Li W Li A Gao YJ Henderson JE Ablation of the Sam68 RNA binding protein protects mice from age-related bone loss PLoS Genet 2005 1 e74 16362077 10.1371/journal.pgen.0010074
das Neves L Duchala CS Tolentino-Silva F Haxhiu MA Colmenares C Macklin WB Campbell CE Butz KG Gronostajski RM Disruption of the murine nuclear factor I-A gene (Nfia) results in perinatal lethality, hydrocephalus, and agenesis of the corpus callosum Proc Natl Acad Sci USA 1999 96 11946 11951 10518556 10.1073/pnas.96.21.11946
Bermingham JR Jr Scherer SS O'Connell S Arroyo E Kalla KA Powell FL Rosenfeld MG Tst-1/Oct-6/SCIP regulates a unique step in peripheral myelination and is required for normal respiration Genes Dev 1996 10 1751 1762 8698235 10.1101/gad.10.14.1751
Nomi M Oishi I Kani S Suzuki H Matsuda T Yoda A Kitamura M Itoh K Takeuchi S Takeda K Akira S Ikeya M Takada S Minami Y Loss of mRor1 enhances the heart and skeletal abnormalities in mRor2-deficient mice: redundant and pleiotropic functions of mRor1 and mRor2 receptor tyrosine kinases Mol Cell Biol 2001 21 8329 8335 11713269 10.1128/MCB.21.24.8329-8335.2001
Li M York JP Zhang P Loss of Cdc20 causes a securin-dependent metaphase arrest in two-cell mouse embryos Mol Cell Biol 2007 27 3481 3488 17325031 10.1128/MCB.02088-06
Gomeza J Hulsmann S Ohno K Eulenburg V Szoke K Richter D Betz H Inactivation of the glycine transporter 1 gene discloses vital role of glial glycine uptake in glycinergic inhibition Neuron 2003 40 785 796 14622582 10.1016/S0896-6273(03)00672-X
Ohtoshi A Behringer RR Neonatal lethality, dwarfism, and abnormal brain development in Dmbx1 mutant mice Mol Cell Biol 2004 24 7548 7558 15314164 10.1128/MCB.24.17.7548-7558.2004
Fujimoto W Shiuchi T Miki T Minokoshi Y Takahashi Y Takeuchi A Kimura K Saito M Iwanaga T Seino S Dmbx1 is essential in agouti-related protein action Proc Natl Acad Sci USA 2007 104 15514 15519 17873059 10.1073/pnas.0707328104
Poltorak A He X Smirnova I Liu MY Van Huffel C Du X Birdwell D Alejos E Silva M Galanos C Freudenberg M Ricciardi-Castagnoli P Layton B Beutler B Defective LPS signaling in C3H/HeJ and C57BL/10ScCr mice: mutations in Tlr4 gene Science 1998 282 2085 2088 9851930 10.1126/science.282.5396.2085
Hentges KE Pollock DD Liu B Justice MJ Regional variation in the density of essential genes in mice PLoS Genet 2007 3 e72 17480122 10.1371/journal.pgen.0030072
Kamath RS Fraser AG Dong Y Poulin G Durbin R Gotta M Kanapin A Le Bot N Moreno S Sohrmann M Welchman DP Zipperlen P Ahringer J Systematic functional analysis of the Caenorhabditis elegans genome using RNAi Nature 2003 421 231 237 12529635 10.1038/nature01278
Finn RD Tate J Mistry J Coggill PC Sammut SJ Hotz HR Ceric G Forslund K Eddy SR Sonnhammer EL Bateman A The Pfam protein families database Nucleic Acids Res 2008 D281 288 18039703
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