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The Journal of investigative dermatology, v.130 no.2, 2010년, pp.500 - 510
Hachem, Jean-Pierre (Department of Dermatology, Universitair Ziekenhuis Brussel-Vrije Universiteit Brussel, Brussels, Belgium) , Roelandt, Truus (Department of Dermatology, Universitair Ziekenhuis Brussel-Vrije Universiteit Brussel, Brussels, Belgium) , Schürer, Nanna (Department of Dermatology, University of Osnabruck, Osnabruck, Germany) , Pu, Xu (Departments of Dermatology and Metabolism, University of California San Francisco, Veterans Affairs Medical Center, San Francisco, California, USA) , Fluhr, Joachim (Bioskin GmbH, Berlin, Germany) , Giddelo, Christina (Department of Dermatology, Universitair Ziekenhuis Brussel-Vrije Universiteit Brussel, Brussels, Belgium) , Man, Mao-Qiang (Departments of Dermatology and Metabolism, University of California San Francisco, Veterans Affairs Medical Center, San Francisco, California, USA) , Crumrine, Debra (Departments of Dermatology and Metabolism, University of California San Francisco, Veterans Affairs Medical Center, San Francisco, California, USA) , Roseeuw, Diane (Department of Dermatology, Universitair Ziekenhuis Brussel-Vrije Universiteit Brussel, Brussels, Belgium) , Feingold, Kenneth R (Departments of Derma) , Mauro, Theodora , Elias, Peter M
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Neutralization of the normally acidic stratum corneum (SC) has deleterious consequences for permeability barrier homeostasis and SC integrity/cohesion attributable to serine proteases (SPs) activation leading to deactivation/degradation of lipid-processing enzymes and corneodesmosomes (CD). ...
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