[논문]Whitening effect of &agr;-bisabolol in Asian women subjects

Lee, J.; Jun, H.; Jung, E.; Ha, J.; Park, D.

doi:10.1111/j.1468-2494.2010.00560.x

Whitening effect of &agr;-bisabolol in Asian women subjects

International journal of cosmetic science, v.32 no.4, 2010년, pp.299 - 303

Lee, J. (Biospectrum Life Science Institute, Gyunggi Do) , Jun, H. (IECKorea Skin Research Center, Suwon, Korea) , Jung, E. (Biospectrum Life Science Institute, Gyunggi Do) , Ha, J. (IECKorea Skin Research Center, Suwon, Korea) , Park, D. (Biospectrum Life Science Institute, Gyunggi Do)

Abstract ▼ AI-Helper

SynopsisAlthough skin pigmentation, which results from the production and distribution of melanin in the epidermis, is the major physiological defence against solar irradiation, hyperpigmentation is a common and distressing problem caused by various inflammatory skin disorders, such as eczema, allergic contact dermatitis and irritant contact dermatitis. We evaluated the effects of a preparation containing &agr;-bisabolol on pigmented skin of a group of subjects. The effectiveness of the active compound, &agr;-bisabolol, in a base-cream preparation for the treatment of pigmented skin was tested on 28 female subjects as follows: the cream was applied once a day to the back for 8 weeks. These same women also applied a vehicle control cream to the pigmented skin. The results were evaluated by clinical and biophysical test methods. After 8 weeks of treatment of the &agr;-bisabolol-containing cream, there was significant lightening effect in the pigmented skin for the majority of the subjects who tested the cream.

Abstract

RésuméEffet blanchissant de l’&agr;-bisabolol chez les femmes asiatiquesBien que la pigmentation de la peau, qui résulte de la production et de la distribution de mélanine dans l’épiderme, soit la défense physiologique majeure contre l’irradiation solaire, l’hyperpigmentation est un problème commun et pénible causé par diverses affections cutanées inflammatoires, comme l’eczéma, la dermatite allergique de contact et la dermatite d’irritation de contact. Nous avons évalué les effets d’une préparation contenant de l’&agr;-bisabolol sur la peau pigmentée d’un groupe de sujets. L’efficacité du composé actif &agr;-bisabolol, dans une crème de base pour le traitement de peau pigmentée a étéévalué sur 28 sujets féminins comme suit : la crème a été appliquée une fois par jour sur le dos pendant 8 semaines. Ces mêmes femmes ont aussi appliqué une crème véhicule de contrôle sur la peau pigmentée. Les résultats ont étéévalués par des méthodes cliniques et biophysiques. Après 8 semaines de traitement par la crème contenant de l’&agr;-bisabolol, il y avait un effet éclaircissant significatif de la peau pigmentée pour la majorité des sujets.

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Whitening effect of &agr;-bisabolol in Asian women subjects

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Whitening effect of &agr;-bisabolol in Asian women subjects

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