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Skin Vaccination against Cervical Cancer Associated Human Papillomavirus with a Novel Micro-Projection Array in a Mouse Model 원문보기

PloS one, v.5 no.10, 2010년, pp.e13460 -   

Corbett, Holly J. (Delivery of Drugs and Genes Group (D2G2), Australian Institute for Bioengineering and Nanotechnology, The University of Queensland, Brisbane, Queensland, Australia) ,  Fernando, Germain J. P. (Delivery of Drugs and Genes Group (D2G2), Australian Institute for Bioengineering and Nanotechnology, The University of Queensland, Brisbane, Queensland, Australia) ,  Chen, Xianfeng (Delivery of Drugs and Genes Group (D2G2), Australian Institute for Bioengineering and Nanotechnology, The University of Queensland, Brisbane, Queensland, Australia) ,  Frazer, Ian H. (Diamantina Institute, Princess Alexandra Hospital, The University of Queensland, Woolloongabba, Queensland, Australia) ,  Kendall, Mark A. F. (Delivery of Drugs and Genes Group (D2G2), Australian Institute for Bioengineering and Nanotechnology, The University of Queensland, Brisbane, Queensland, Australia)

Abstract AI-Helper 아이콘AI-Helper

BackgroundBetter delivery systems are needed for routinely used vaccines, to improve vaccine uptake. Many vaccines contain alum or alum based adjuvants. Here we investigate a novel dry-coated densely-packed micro-projection array skin patch (Nanopatch™) as an alternate delivery system to intramuscul...

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