최소 단어 이상 선택하여야 합니다.
최대 10 단어까지만 선택 가능합니다.
다음과 같은 기능을 한번의 로그인으로 사용 할 수 있습니다.
NTIS 바로가기Genes, chromosomes & cancer, v.50 no.2, 2011년, pp.122 - 135
Yang, Ju Dong (Miles and Shirley Fiterman Center for Digestive Diseases, College of Medicine, Mayo Clinic and Mayo Clinic Cancer Center, Rochester, MN) , Sun, Zhifu (Department of Biomedical Statistics and Informatics, College of Medicine, Mayo Clinic and Mayo Clinic Cancer Center, Rochester, MN) , Hu, Chunling (Miles and Shirley Fiterman Center for Digestive Diseases, College of Medicine, Mayo Clinic and Mayo Clinic Cancer Center, Rochester, MN) , Lai, Jinping (Miles and Shirley Fiterman Center for Digestive Diseases, College of Medicine, Mayo Clinic and Mayo Clinic Cancer Center, Rochester, MN) , Dove, Rebecca (Miles and Shirley Fiterman Center for Digestive Diseases, College of Medicine, Mayo Clinic and Mayo Clinic Cancer Center, Rochester, MN) , Nakamura, Ikuo (Miles and Shirley Fiterman Center for Digestive Diseases, College of Medicine, Mayo Clinic and Mayo Clinic Cancer Center, Rochester, MN) , Lee, Ju‐Seog (Department of Systems Biology, The University) , Thorgeirsson, Snorri S. , Kang, Koo Jeong , Chu, In‐Sun , Roberts, Lewis R.
AbstractThe heparin‐degrading endosulfatases sulfatase 1 (SULF1) and sulfatase 2 (SULF2) have opposing effects in hepatocarcinogenesis despite structural similarity. Using mRNA expression arrays, we analyzed the correlations of SULF expression with signaling networks in human hepatocellular ca...
Ai X , Do AT , Lozynska O , Kusche‐Gullberg M , Lindahl U , Emerson CP , Jr . 2003 . QSulf1 remodels the 6‐O sulfation states of cell surface heparan sulfate proteoglycans to promote Wnt signaling . J Cell Biol 162 : 341 – 351 .
Battaglia S , Benzoubir N , Nobilet S , Charneau P , Samuel D , Zignego AL , Atfi A , Brechot C , Bourgeade MF . 2009 . Liver cancer‐derived hepatitis C virus core proteins shift TGF‐beta responses from tumor suppression to epithelial‐mesenchymal transition . PLoS One 4 : e4355 .
Benetti A , Berenzi A , Gambarotti M , Garrafa E , Gelati M , Dessy E , Portolani N , Piardi T , Giulini SM , Caruso A , Invernici G , Parati E , Nicosia R , Alessandri G . 2008 . Transforming growth factor‐beta1 and CD105 promote the migration of hepatocellular carcinoma‐derived endothelium . Cancer Res 68 : 8626 – 8634 .
Briggs MW , Li Z , Sacks DB . 2002 . IQGAP1‐mediated stimulation of transcriptional co‐activation by beta‐catenin is modulated by calmodulin . J Biol Chem 277 : 7453 – 7465 .
Chau BN , Diaz RL , Saunders MA , Cheng C , Chang AN , Warrener P , Bradshaw J , Linsley PS , Cleary MA . 2009 . Identification of SULF2 as a novel transcriptional target of p53 by use of integrated genomic analyses . Cancer Res 69 : 1368 – 1374 .
Coulouarn C , Factor VM , Thorgeirsson SS . 2008 . Transforming growth factor‐beta gene expression signature in mouse hepatocytes predicts clinical outcome in human cancer . Hepatology 47 : 2059 – 2067 .
Dai Y , Yang Y , MacLeod V , Yue X , Rapraeger AC , Shriver Z , Venkataraman G , Sasisekharan R , Sanderson RD . 2005 . HSulf‐1 and HSulf‐2 are potent inhibitors of myeloma tumor growth in vivo . J Biol Chem 280 : 40066 – 40073 .
Danesin C , Agius E , Escalas N , Ai X , Emerson C , Cochard P , Soula C . 2006 . Ventral neural progenitors switch toward an oligodendroglial fate in response to increased Sonic hedgehog (Shh) activity: Involvement of Sulfatase 1 in modulating Shh signaling in the ventral spinal cord . J Neurosci 26 : 5037 – 5048 .
Dhoot GK , Gustafsson MK , Ai X , Sun W , Standiford DM , Emerson CP , Jr . 2001 . Regulation of Wnt signaling and embryo patterning by an extracellular sulfatase . Science 293 : 1663 – 1666 .
Dredge K , Hammond E , Davis K , Li CP , Liu L , Johnstone K , Handley P , Wimmer N , Gonda TJ , Gautam A , Ferro V , Bytheway I . 2010 . The PG500 series: Novel heparan sulfate mimetics as potent angiogenesis and heparanase inhibitors for cancer therapy . Invest New Drugs 28 : 276 – 283 .
Fujita K , Takechi E , Sakamoto N , Sumiyoshi N , Izumi S , Miyamoto T , Matsuura S , Tsurugaya T , Akasaka K , Yamamoto T . 2010 . HpSulf, a heparan sulfate 6‐O‐endosulfatase, is involved in the regulation of VEGF signaling during sea urchin development . Mech Dev 127 : 235 – 245 .
Ho YD , Joyal JL , Li Z , Sacks DB . 1999 . IQGAP1 integrates Ca2+/calmodulin and Cdc42 signaling . J Biol Chem 274 : 464 – 470 .
Hong L , Sun H , Lv X , Yang D , Zhang J , Shi Y . 2010 . Expression of periostin in the serum of NSCLC and its function on proliferation and migration of human lung adenocarcinoma cell line (A549) in vitro . Mol Biol Rep 37 : 2285 – 2293 .
Hoshida Y , Nijman SM , Kobayashi M , Chan JA , Brunet JP , Chiang DY , Villanueva A , Newell P , Ikeda K , Hashimoto M , et al. 2009 . Integrative transcriptome analysis reveals common molecular subclasses of human hepatocellular carcinoma . Cancer Res 69 : 7385 – 7392 .
Hossain MM , Hosono‐Fukao T , Tang R , Sugaya N , van Kuppevelt TH , Jenniskens GJ , Kimata K , Rosen SD , Uchimura K . 2010 . Direct detection of HSulf‐1 and HSulf‐2 activities on extracellular heparan sulfate and their inhibition by PI‐88 . Glycobiology 20 : 175 – 186 .
Hu L , Lau SH , Tzang CH , Wen JM , Wang W , Xie D , Huang M , Wang Y , Wu MC , Huang JF , Zeng WF , Sham JS , Yang M , Guan XY . 2004 . Association of Vimentin overexpression and hepatocellular carcinoma metastasis . Oncogene 23 : 298 – 302 .
Iizuka N , Tamesa T , Sakamoto K , Miyamoto T , Hamamoto Y , Oka M . 2006 . Different molecular pathways determining extrahepatic and intrahepatic recurrences of hepatocellular carcinoma . Oncol Rep 16 : 1137 – 1142 .
Kalus I , Salmen B , Viebahn C , von Figura K , Schmitz D , D'Hooge R , Dierks T . 2009 . Differential involvement of the extracellular 6‐O‐endosulfatases Sulf1 and Sulf2 in brain development and neuronal and behavioural plasticity . J Cell Mol Med 13 : 4505 – 4521 .
Kuroda S , Fukata M , Nakagawa M , Fujii K , Nakamura T , Ookubo T , Izawa I , Nagase T , Nomura N , Tani H , Shoji I , Matsuura Y , Yonehara S , Kaibuchi K . 1998 . Role of IQGAP1, a target of the small GTPases Cdc42 and Rac1, in regulation of E‐cadherin‐ mediated cell–cell adhesion . Science 281 : 832 – 835 .
Lai J , Chien J , Staub J , Avula R , Greene EL , Matthews TA , Smith DI , Kaufmann SH , Roberts LR , Shridhar V . 2003 . Loss of HSulf‐1 up‐regulates heparin‐binding growth factor signaling in cancer . J Biol Chem 278 : 23107 – 23117 .
Lai JP , Chien J , Strome SE , Staub J , Montoya DP , Greene EL , Smith DI , Roberts LR , Shridhar V . 2004a . HSulf‐1 modulates HGF‐mediated tumor cell invasion and signaling in head and neck squamous carcinoma . Oncogene 23 : 1439 – 1447 .
Lai JP , Chien JR , Moser DR , Staub JK , Aderca I , Montoya DP , Matthews TA , Nagorney DM , Cunningham JM , Smith DI , Greene EL , Shridhar V , Roberts LR . 2004b . hSulf1 Sulfatase promotes apoptosis of hepatocellular cancer cells by decreasing heparin‐binding growth factor signaling . Gastroenterology 126 : 231 – 248 .
Lai JP , Yu C , Moser CD , Aderca I , Han T , Garvey TD , Murphy LM , Garrity‐Park MM , Shridhar V , Adjei AA , Roberts LR . 2006 . SULF1 inhibits tumor growth and potentiates the effects of histone deacetylase inhibitors in hepatocellular carcinoma . Gastroenterology 130 : 2130 – 2144 .
Lai JP , Sandhu DS , Yu C , Han T , Moser CD , Jackson KK , Guerrero RB , Aderca I , Isomoto H , Garrity‐Park MM , Zou H , Shire AM , Nagorney DM , Sanderson SO , Adjei AA , Lee JS , Thorgeirsson SS , Roberts LR . 2008 . Sulfatase 2 up‐regulates glypican 3, promotes fibroblast growth factor signaling, and decreases survival in hepatocellular carcinoma . Hepatology 47 : 1211 – 1222 .
Lai JP , Oseini AM , Moser CD , Yu C , Elsawa SF , Hu C , Nakamura I , Han T , Aderca I , Isomoto H , Garrity‐Park MM , Shire AM , Li J , Sanderson SO , Adjei AA , Fernandez‐Zapico ME , Roberts LR . 2010 . The oncogenic effect of sulfatase 2 in human hepatocellular carcinoma is mediated in part by glypican 3‐dependent Wnt activation . Hepatology 52 : 1680 – 1689 .
Lamanna WC , Baldwin RJ , Padva M , Kalus I , Ten Dam G , van Kuppevelt TH , Gallagher JT , von Figura K , Dierks T , Merry CL . 2006 . Heparan sulfate 6‐O‐endosulfatases: Discrete in vivo activities and functional co‐operativity . Biochem J 400 : 63 – 73 .
Lazarevich NL , Cheremnova OA , Varga EV , Ovchinnikov DA , Kudrjavtseva EI , Morozova OV , Fleishman DI , Engelhardt NV , Duncan SA . 2004 . Progression of HCC in mice is associated with a downregulation in the expression of hepatocyte nuclear factors . Hepatology 39 : 1038 – 1047 .
Lee JS , Heo J , Libbrecht L , Chu IS , Kaposi‐Novak P , Calvisi DF , Mikaelyan A , Roberts LR , Demetris AJ , Sun Z , Nevens F , Roskams T , Thorgeirsson SS . 2006 . A novel prognostic subtype of human hepatocellular carcinoma derived from hepatic progenitor cells . Nat Med 12 : 410 – 416 .
Lemjabbar‐Alaoui H , van Zante A , Singer MS , Xue Q , Wang YQ , Tsay D , He B , Jablons DM , Rosen SD . 2010 . Sulf‐2, a heparan sulfate endosulfatase, promotes human lung carcinogenesis . Oncogene 29 : 635 – 646 .
Li J , Kleeff J , Abiatari I , Kayed H , Giese NA , Felix K , Giese T , Buchler MW , Friess H . 2005 . Enhanced levels of Hsulf‐1 interfere with heparin‐binding growth factor signaling in pancreatic cancer . Mol Cancer 4 : 14 .
Lum DH , Tan J , Rosen SD , Werb Z . 2007 . Gene trap disruption of the mouse heparan sulfate 6‐O‐endosulfatase gene, Sulf2 . Mol Cell Biol 27 : 678 – 688 .
Mataraza JM , Briggs MW , Li Z , Entwistle A , Ridley AJ , Sacks DB . 2003 . IQGAP1 promotes cell motility and invasion . J Biol Chem 278 : 41237 – 41245 .
Mishra L , Banker T , Murray J , Byers S , Thenappan A , He AR , Shetty K , Johnson L , Reddy EP . 2009 . Liver stem cells and hepatocellular carcinoma . Hepatology 49 : 318 – 329 .
Morimoto‐Tomita M , Uchimura K , Bistrup A , Lum DH , Egeblad M , Boudreau N , Werb Z , Rosen SD . 2005 . Sulf‐2, a proangiogenic heparan sulfate endosulfatase, is upregulated in breast cancer . Neoplasia 7 : 1001 – 1010 .
Murata M , Matsuzaki K , Yoshida K , Sekimoto G , Tahashi Y , Mori S , Uemura Y , Sakaida N , Fujisawa J , Seki T , Kobayashi K , Yokote K , Koike K , Okazaki K . 2009 . Hepatitis B virus X protein shifts human hepatic transforming growth factor (TGF)‐beta signaling from tumor suppression to oncogenesis in early chronic hepatitis B . Hepatology 49 : 1203 – 1217 .
Narita K , Staub J , Chien J , Meyer K , Bauer M , Friedl A , Ramakrishnan S , Shridhar V . 2006 . HSulf‐1 inhibits angiogenesis and tumorigenesis in vivo . Cancer Res 66 : 6025 – 6032 .
Narita K , Chien J , Mullany SA , Staub J , Qian X , Lingle WL , Shridhar V . 2007 . Loss of HSulf‐1 expression enhances autocrine signaling mediated by amphiregulin in breast cancer . J Biol Chem 282 : 14413 – 14420 .
Nawroth R , van Zante A , Cervantes S , McManus M , Hebrok M , Rosen SD . 2007 . Extracellular sulfatases, elements of the Wnt signaling pathway, positively regulate growth and tumorigenicity of human pancreatic cancer cells . PLoS One 2 : e392 .
Ren JG , Li Z , Sacks DB . 2008 . IQGAP1 integrates Ca2+/calmodulin and B‐Raf signaling . J Biol Chem 283 : 22972 – 22982 .
Roy M , Li Z , Sacks DB . 2004 . IQGAP1 binds ERK2 and modulates its activity . J Biol Chem 279 : 17329 – 17337 .
Roy M , Li Z , Sacks DB . 2005 . IQGAP1 is a scaffold for mitogen‐activated protein kinase signaling . Mol Cell Biol 25 : 7940 – 7952 .
Ruan K , Bao S , Ouyang G . 2009 . The multifaceted role of periostin in tumorigenesis . Cell Mol Life Sci 66 : 2219 – 2230 .
Schmidt VA , Chiariello CS , Capilla E , Miller F , Bahou WF . 2008 . Development of hepatocellular carcinoma in Iqgap2‐deficient mice is IQGAP1 dependent . Mol Cell Biol 28 : 1489 – 1502 .
Uchimura K , Morimoto‐Tomita M , Bistrup A , Li J , Lyon M , Gallagher J , Werb Z , Rosen SD . 2006 . HSulf‐2, an extracellular endoglucosamine‐6‐sulfatase, selectively mobilizes heparin‐bound growth factors and chemokines: Effects on VEGF, FGF‐1, and SDF‐1 . BMC Biochem 7 : 2 .
Viviano BL , Paine‐Saunders S , Gasiunas N , Gallagher J , Saunders S . 2004 . Domain‐specific modification of heparan sulfate by Qsulf1 modulates the binding of the bone morphogenetic protein antagonist Noggin . J Biol Chem 279 : 5604 – 5611 .
Wang Y , Wang A , Wang F , Wang M , Zhu M , Ma Y , Wu R . 2008 . IQGAP1 activates Tcf signal independent of Rac1 and Cdc42 in injury and repair of bronchial epithelial cells . Exp Mol Pathol 85 : 122 – 128 .
Yamashita T , Ji J , Budhu A , Forgues M , Yang W , Wang HY , Jia H , Ye Q , Qin LX , Wauthier E , Reid LM , Minato H , Honda M , Kaneko S , Tang ZY , Wang XW . 2009 . EpCAM‐positive hepatocellular carcinoma cells are tumor‐initiating cells with stem/progenitor cell features . Gastroenterology 136 : 1012 – 1024 .
Yin C , Lin Y , Zhang X , Chen YX , Zeng X , Yue HY , Hou JL , Deng X , Zhang JP , Han ZG , Xie WF . 2008 . Differentiation therapy of hepatocellular carcinoma in mice with recombinant adenovirus carrying hepatocyte nuclear factor‐4alpha gene . Hepatology 48 : 1528 – 1539 .
Yue X , Li X , Nguyen HT , Chin DR , Sullivan DE , Lasky JA . 2008 . Transforming growth factor‐beta1 induces heparan sulfate 6‐O‐endosulfatase 1 expression in vitro and in vivo . J Biol Chem 283 : 20397 – 20407 .
Zhou J , Liang S , Fang L , Chen L , Tang M , Xu Y , Fu A , Yang J , Wei Y . 2009 . Quantitative proteomic analysis of HepG2 Cells treated with quercetin suggests IQGAP1 involved in quercetin‐induced regulation of cell proliferation and migration . Omics 13 : 93 – 103 .
*원문 PDF 파일 및 링크정보가 존재하지 않을 경우 KISTI DDS 시스템에서 제공하는 원문복사서비스를 사용할 수 있습니다.
저자가 공개 리포지터리에 출판본, post-print, 또는 pre-print를 셀프 아카이빙 하여 자유로운 이용이 가능한 논문
※ AI-Helper는 부적절한 답변을 할 수 있습니다.