다음과 같은 기능을 한번의 로그인으로 사용 할 수 있습니다.
NTIS 바로가기
Cell, v.144 no.5, 2011년, pp.646 - 674
Hanahan, Douglas (The Swiss Institute for Experimental Cancer Research (ISREC), School of Life Sciences, EPFL, Lausanne CH-1015, Switzerland) , Weinberg, Robert A. (Whitehead Institute for Biomedical Research, Ludwig)
AI-Helper
The hallmarks of cancer comprise six biological capabilities acquired during the multistep development of human tumors. The hallmarks constitute an organizing principle for rationalizing the complexities of neoplastic disease. They include sustaining proliferative signaling, evading growth suppresso...
Oncogene Adams 26 1324 2007 10.1038/sj.onc.1210220 The Bcl-2 apoptotic switch in cancer development and therapy
Nat. Rev. Cancer Aguirre-Ghiso 7 834 2007 10.1038/nrc2256 Models, mechanisms and clinical evidence for cancer dormancy
Methods Mol. Biol. Ahmed 467 3 2009 10.1007/978-1-59745-241-0_1 Angiogenic signalling pathways
Proc. Natl. Acad. Sci. USA Al-Hajj 100 3983 2003 10.1073/pnas.0530291100 Prospective identification of tumorigenic breast cancer cells
Clin. Cancer Res. Amaravadi 13 7271 2007 10.1158/1078-0432.CCR-07-1595 The roles of therapy-induced autophagy and necrosis in cancer treatment
Nat. Genet. Amit 39 503 2007 10.1038/ng1987 A module of negative feedback regulators defines growth factor signaling
Int. J. Cancer Apel 125 991 2009 10.1002/ijc.24500 Autophagy-A double-edged sword in oncology
Nat. Med. Artandi 6 852 2000 10.1038/78595 Mice without telomerase: what can they teach us about human cancer?
Carcinogenesis Artandi 31 9 2010 10.1093/carcin/bgp268 Telomeres and telomerase in cancer
Eur. J. Cancer Azam 46 1323 2010 10.1016/j.ejca.2010.02.020 Mechanisms of resistance to antiangiogenesis therapy
Semin. Cancer Biol. Baeriswyl 19 329 2009 10.1016/j.semcancer.2009.05.003 The angiogenic switch in carcinogenesis
Curr. Opin. Genet. Dev. Baluk 15 102 2005 10.1016/j.gde.2004.12.005 Cellular abnormalities of blood vessels as targets in cancer
Eur. J. Cancer Barkan 46 1181 2010 10.1016/j.ejca.2010.02.027 Extracellular matrix: a gatekeeper in the transition from dormancy to metastatic growth
Annu. Rev. Genet. Barnes 38 445 2004 10.1146/annurev.genet.38.072902.092448 Repair and genetic consequences of endogenous DNA base damage in mammalian cells
Development Barrallo-Gimeno 132 3151 2005 10.1242/dev.01907 The Snail genes as inducers of cell movement and survival: implications in development and cancer
Dev. Cell Berdasco 19 698 2010 10.1016/j.devcel.2010.10.005 Aberrant epigenetic landscape in cancer: How cellular identity goes awry
Nat. Rev. Cancer Bergers 3 401 2003 10.1038/nrc1093 Tumorigenesis and the angiogenic switch
Nat. Rev. Cancer Bergers 8 592 2008 10.1038/nrc2442 Modes of resistance to anti-angiogenic therapy
Neuro-oncol. Bergers 7 452 2005 10.1215/S1152851705000232 The role of pericytes in blood-vessel formation and maintenance
Cancer Metastasis Rev. Bergfeld 29 249 2010 10.1007/s10555-010-9222-7 Bone marrow-derived mesenchymal stem cells and the tumor microenvironment
Cold Spring Harb. Perspect. Biol. Berx 1 a003129 2009 10.1101/cshperspect.a003129 Involvement of members of the cadherin superfamily in cancer
Nature Bhowmick 432 332 2004 10.1038/nature03096 Stromal fibroblasts in cancer initiation and progression
Nat. Rev. Cancer Bierie 6 506 2006 10.1038/nrc1926 Tumour microenvironment: TGFbeta: the molecular Jekyll and Hyde of cancer
Curr. Opin. Immunol. Bindea 22 215 2010 10.1016/j.coi.2010.02.006 Natural immunity to cancer in humans
Nat. Immunol. Biswas 11 889 2010 10.1038/ni.1937 Macrophage plasticity and interaction with lymphocyte subsets: cancer as a paradigm
Nat. Rev. Genet. Blasco 6 611 2005 10.1038/nrg1656 Telomeres and human disease: ageing, cancer and beyond
Nature Boiko 466 133 2010 10.1038/nature09161 Human melanoma-initiating cells express neural crest nerve growth factor receptor CD271
Nat. Med. Bonnet 3 730 1997 10.1038/nm0797-730 Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell
Nature Bos 459 1005 2009 10.1038/nature08021 Genes that mediate breast cancer metastasis to the brain
Proc. Natl. Acad. Sci. USA Brabletz 98 10356 2001 10.1073/pnas.171610498 Variable beta-catenin expression in colorectal cancers indicates tumor progression driven by the tumor environment
Nat. Rev. Cancer Brabletz 5 744 2005 10.1038/nrc1694 Opinion: migrating cancer stem cells - an integrated concept of malignant tumour progression
Mol. Cancer Ther. Buck 6 532 2007 10.1158/1535-7163.MCT-06-0462 Loss of homotypic cell adhesion by epithelial-mesenchymal transition or mutation limits sensitivity to epidermal growth factor receptor inhibition
Nat. Rev. Cancer Burkhart 8 671 2008 10.1038/nrc2399 Cellular mechanisms of tumour suppression by the retinoblastoma gene
Angiogenesis Cabrita 11 53 2008 10.1007/s10456-008-9089-1 Sprouty proteins, masterminds of receptor tyrosine kinase signaling
Nature Campbell 467 1109 2010 10.1038/nature09460 The patterns and dynamics of genomic instability in metastatic pancreatic cancer
Nat. Rev. Drug Discov. Cao 9 107 2010 10.1038/nrd3055 Adipose tissue angiogenesis as a therapeutic target for obesity and metabolic diseases
Oncology Carmeliet 69 Suppl 3 4 2005 10.1159/000088478 VEGF as a key mediator of angiogenesis in cancer
Nature Carmeliet 407 249 2000 10.1038/35025220 Angiogenesis in cancer and other diseases
Nat. Rev. Cancer Cavallaro 4 118 2004 10.1038/nrc1276 Cell adhesion and signalling by cadherins and Ig-CAMs in cancer
Mol. Cancer Res. Cheng 6 1521 2008 10.1158/1541-7786.MCR-07-2203 Transforming growth factor-beta signaling-deficient fibroblasts enhance hepatocyte growth factor signaling in mammary carcinoma cells to promote scattering and invasion
Nat. Genet. Chin 36 984 2004 10.1038/ng1409 In situ analyses of genome instability in breast cancer
Curr. Opin. Genet. Dev. Cho 18 1 2008 10.1016/j.gde.2008.01.017 Recent advances in cancer stem cells
Mol. Cell Ciccia 40 179 2010 10.1016/j.molcel.2010.09.019 The DNA damage response: making it safe to play with knives
Am. J. Pathol. Coffelt 176 1564 2010 10.2353/ajpath.2010.090786 Elusive identities and overlapping phenotypes of proangiogenic myeloid cells in tumors
J. Pathol. Coghlin 222 1 2010 10.1002/path.2727 Current and emerging concepts in tumour metastasis
Nat. Rev. Cancer Collado 10 51 2010 10.1038/nrc2772 Senescence in tumours: evidence from mice and humans
Carcinogenesis Colotta 30 1073 2009 10.1093/carcin/bgp127 Cancer-related inflammation, the seventh hallmark of cancer: links to genetic instability
Cell Res. Cong 18 725 2008 10.1038/cr.2008.74 Actions of human telomerase beyond telomeres
Proc. Natl. Acad. Sci. USA Creighton 106 13820 2009 10.1073/pnas.0905718106 Residual breast cancers after conventional therapy display mesenchymal as well as tumor-initiating features
J. Cell Biol. Curto 177 893 2007 10.1083/jcb.200703010 Contact-dependent inhibition of EGFR signaling by Nf2/Merlin
Oncogene Davies 29 5545 2010 10.1038/onc.2010.323 Analysis of the genome to personalize therapy for melanoma
Cell Metab. DeBerardinis 7 11 2008 10.1016/j.cmet.2007.10.002 The biology of cancer: Metabolic reprogramming fuels cell growth and proliferation
Cell Tissue Res. Dejana 335 17 2009 10.1007/s00441-008-0694-5 Organization and signaling of endothelial cell-to-cell junctions in various regions of the blood and lymphatic vascular trees
Ann. Oncol. Demicheli 19 1821 2008 10.1093/annonc/mdn386 The effects of surgery on tumor growth: a century of investigations
Cancer Metastasis Rev. DeNardo 29 309 2010 10.1007/s10555-010-9223-6 Interactions between lymphocytes and myeloid cells regulate pro- versus anti-tumor immunity
Trends Immunol. De Palma 28 519 2007 10.1016/j.it.2007.09.004 Tie2-expressing monocytes: regulation of tumor angiogenesis and therapeutic implications
Oncogene Deshpande 24 2909 2005 10.1038/sj.onc.1208618 Cyclins and cdks in development and cancer: a perspective
Nat. Rev. Cancer de Visser 6 24 2006 10.1038/nrc1782 Paradoxical roles of the immune system during cancer development
Endocr. Dev. Dirat 19 45 2010 10.1159/000316896 Unraveling the obesity and breast cancer links: a role for cancer-associated adipocytes?
N. Engl. J. Med. Dvorak 315 1650 1986 10.1056/NEJM198612253152606 Tumors: wounds that do not heal. Similarities between tumor stroma generation and wound healing
Clin. Cancer Res. Ebos 15 5020 2009 10.1158/1078-0432.CCR-09-0095 Tumor and host-mediated pathways of resistance and disease progression in response to antiangiogenic therapy
Dev. Cell Egeblad 18 884 2010 10.1016/j.devcel.2010.05.012 Tumors as organs: complex tissues that interface with the entire organism
Brain El Hallani 133 973 2010 10.1093/brain/awq044 A new alternative mechanism in glioblastoma vascularization: tubular vasculogenic mimicry
Nature Ellis 458 290 2009 10.1038/458290a Cancer: The nuances of therapy
Nat. Rev. Genet. Esteller 8 286 2007 10.1038/nrg2005 Cancer epigenomics: DNA methylomes and histone-modification maps
Curr. Opin. Genet. Dev. Evan 19 25 2009 10.1016/j.gde.2008.11.009 Cellular senescence: hot or what?
Science Evan 281 1317 1998 10.1126/science.281.5381.1317 A matter of life and cell death
J. Mol. Cell. Cardiol. Fang 50 290 2011 10.1016/j.yjmcc.2010.10.024 Stem cells in tumor angiogenesis
Radiother. Oncol. Feron 92 329 2009 10.1016/j.radonc.2009.06.025 Pyruvate into lactate and back: from the Warburg effect to symbiotic energy fuel exchange in cancer cells
Cancer Cell Feldser 11 461 2007 10.1016/j.ccr.2007.02.026 Short telomeres limit tumor progression in vivo by inducing senescence
Arterioscler. Thromb. Vasc. Biol. Ferrara 29 789 2009 10.1161/ATVBAHA.108.179663 Vascular endothelial growth factor
Cytokine Growth Factor Rev. Ferrara 21 21 2010 10.1016/j.cytogfr.2009.11.003 Pathways mediating VEGF-independent tumor angiogenesis
J. Clin. Oncol. Ferrone 28 4045 2010 10.1200/JCO.2010.27.9992 Dual roles for immunity in gastrointestinal cancers
Nat. Rev. Cancer Fidler 3 453 2003 10.1038/nrc1098 The pathogenesis of cancer metastasis: the ‘seed and soil’ hypothesis revisited
Semin. Oncol. Folkman 29 6, Suppl 16 15 2002 10.1016/S0093-7754(02)70065-1 Role of angiogenesis in tumor growth and metastasis
Annu. Rev. Med. Folkman 57 1 2006 10.1146/annurev.med.57.121304.131306 Angiogenesis
Nature Folkman 427 787 2004 10.1038/427787a Cancer without disease
DNA Repair (Amst.) Friedberg 5 986 2006 10.1016/j.dnarep.2006.05.005 DNA repair: from molecular mechanism to human disease
Cancer Res. Friedl 68 7247 2008 10.1158/0008-5472.CAN-08-0784 Tube travel: the role of proteases in individual and collective cancer cell invasion
J. Cell Biol. Friedl 188 11 2010 10.1083/jcb.200909003 Plasticity of cell migration: a multiscale tuning model
Arterioscler. Thromb. Vasc. Biol. Gaengel 29 630 2009 10.1161/ATVBAHA.107.161521 Endothelial-mural cell signaling in vascular development and angiogenesis
Cell Galluzzi 135 1161 2008 10.1016/j.cell.2008.12.004 Necroptosis: a specialized pathway of programmed necrosis
Nat. Rev. Drug Discov. Garzon 9 775 2010 10.1038/nrd3179 Targeting microRNAs in cancer: rationale, strategies and challenges
J. Mol. Med. Gerhardt 86 135 2008 10.1007/s00109-007-0258-2 Pericytes: gatekeepers in tumour cell metastasis?
Oncogene Ghebranious 17 3385 1998 10.1038/sj.onc.1202573 Mouse models in tumor suppression
Curr. Top. Microbiol. Immunol. Giaccia 345 31 2010 Role of carcinoma-associated fibroblasts and hypoxia in tumor progression
Nat. Rev. Cancer Gilbertson 7 733 2007 10.1038/nrc2246 Making a tumour's bed: glioblastoma stem cells and the vascular niche
Genes Dev. Gocheva 24 241 2010 10.1101/gad.1874010 IL-4 induces cathepsin protease activity in tumor-associated macrophages to promote cancer growth and invasion
Cell Grivennikov 140 883 2010 10.1016/j.cell.2010.01.025 Immunity, inflammation, and cancer
Cold Spring Harb. Symp. Quant. Biol. Gupta 70 149 2005 10.1101/sqb.2005.70.018 Identifying site-specific metastasis genes and functions
Nat. Med. Gupta 15 1010 2009 10.1038/nm0909-1010 Cancer stem cells: mirage or reality?
Cell Hanahan 86 353 1996 10.1016/S0092-8674(00)80108-7 Patterns and emerging mechanisms of the angiogenic switch during tumorigenesis
Cell Hanahan 100 57 2000 10.1016/S0092-8674(00)81683-9 The hallmarks of cancer
Mod. Pathol. Hansel 19 772 2006 10.1038/modpathol.3800591 Telomere length variation in biliary tract metaplasia, dysplasia, and carcinoma
Curr. Mol. Med. Hardee 9 435 2009 10.2174/156652409788167122 Novel imaging provides new insights into mechanisms of oxygen transport in tumors
Mol. Cell Harper 28 739 2007 10.1016/j.molcel.2007.11.015 The DNA damage response: Ten years after
Oncogene Hezel 27 6908 2008 10.1038/onc.2008.342 LKB1; linking cell structure and tumor suppression
Int. J. Cancer Hlubek 121 1941 2007 10.1002/ijc.22916 Heterogeneous expression of Wnt/beta-catenin target genes within colorectal cancer
J. Cell. Physiol. Hugo 213 374 2007 10.1002/jcp.21223 Epithelial-mesenchymal and mesenchymal-epithelial transitions in carcinoma progression
Cell Hsu 134 703 2008 10.1016/j.cell.2008.08.021 Cancer cell metabolism: Warburg and beyond
Curr. Opin. Cell Biol. Hynes 21 177 2009 10.1016/j.ceb.2008.12.010 ErbB receptors and signaling pathways in cancer
Nat. Rev. Cancer Ikushima 10 415 2010 10.1038/nrc2853 TGFbeta signalling: a complex web in cancer progression
Cancer Cell Ince 12 160 2007 10.1016/j.ccr.2007.06.013 Transformation of different human breast epithelial cell types leads to distinct tumor phenotypes
Nature Jackson 461 1071 2009 10.1038/nature08467 The DNA-damage response in human biology and disease
Adv. Cancer Res. Jiang 102 19 2009 10.1016/S0065-230X(09)02002-8 PI3K/PTEN signaling in angiogenesis and tumorigenesis
Immunol. Rev. Johansson 222 145 2008 10.1111/j.1600-065X.2008.00600.x Polarized immune responses differentially regulate cancer development
Cell Jones 128 683 2007 10.1016/j.cell.2007.01.029 The epigenomics of cancer
Genes Dev. Jones 23 537 2009 10.1101/gad.1756509 Tumor suppressors and cell metabolism: a recipe for cancer growth
Nat. Rev. Cancer Joyce 9 239 2009 10.1038/nrc2618 Microenvironmental regulation of metastasis
Nat. Rev. Cancer Junttila 9 821 2009 10.1038/nrc2728 p53-a Jack of all trades but master of none
Nat. Rev. Cancer Kalluri 6 392 2006 10.1038/nrc1877 Fibroblasts in cancer
J. Neurosci. Kang 24 1280 2004 10.1523/JNEUROSCI.4082-03.2004 Ectopic expression of the catalytic subunit of telomerase protects against brain injury resulting from ischemia and NMDA-induced neurotoxicity
Cell Karin 124 823 2006 10.1016/j.cell.2006.02.016 Innate immunity gone awry: linking microbial infections to chronic inflammation and cancer
Breast Dis. Karnoub 26 75 2006 10.3233/BD-2007-26107 Chemokine networks and breast cancer metastasis
Nature Karnoub 449 557 2007 10.1038/nature06188 Mesenchymal stem cells within tumour stroma promote breast cancer metastasis
Mol. Cancer Res. Kastan 6 517 2008 10.1158/1541-7786.MCR-08-0020 DNA damage responses: mechanisms and roles in human disease: 2007 G.H.A. Clowes Memorial Award Lecture
Am. J. Clin. Pathol. Kawai 127 254 2007 10.1309/91PY0RBD9W8Y5GNX Telomere length and telomerase expression in atypical adenomatous hyperplasia and small bronchioloalveolar carcinoma of the lung
Cell. Mol. Life Sci. Kazerounian 65 700 2008 10.1007/s00018-007-7486-z Thrombospondins in cancer
Curr. Opin. Cell Biol. Kenific 22 241 2010 10.1016/j.ceb.2009.10.008 Autophagy and metastasis: another double-edged sword
Future Oncol. Kennedy 6 127 2010 10.2217/fon.09.145 Tumor metabolism of lactate: the influence and therapeutic potential for MCT and CD147 regulation
Cell Kessenbrock 141 52 2010 10.1016/j.cell.2010.03.015 Matrix metalloproteinases: Regulators of the tumor microenvironment
Cell Kim 139 1315 2009 10.1016/j.cell.2009.11.025 Tumor self-seeding by circulating cancer cells
Immunology Kim 121 1 2007 10.1111/j.1365-2567.2007.02587.x Cancer immunoediting from immune surveillance to immune escape
Nature Kinzler 386 761 1997 10.1038/386761a0 Cancer-susceptibility genes. Gatekeepers and caretakers
Nat. Rev. Cancer Klein 9 302 2009 10.1038/nrc2627 Parallel progression of primary tumours and metastases
Am. J. Pathol. Klymkowsky 174 1588 2009 10.2353/ajpath.2009.080545 Epithelial-mesenchymal transition: a cancer researcher's conceptual friend and foe
Curr. Opin. Genet. Dev. Korkola 20 4 2010 10.1016/j.gde.2009.11.005 Breast cancer genomes-form and function
Stem Cell Res. (Amst.) Kovacic 2 2 2009 10.1016/j.scr.2008.05.005 Resident vascular progenitor cells: an emerging role for non-terminally differentiated vessel-resident cells in vascular biology
Cancer Cell Kroemer 13 472 2008 10.1016/j.ccr.2008.05.005 Tumor cell metabolism: Cancer's Achilles' heel
J. Leukoc. Biol. Lamagna 80 677 2006 10.1189/jlb.0506309 The bone marrow constitutes a reservoir of pericyte progenitors
Nature Lane 358 15 1992 10.1038/358015a0 Cancer. p53, guardian of the genome
Cell Lemmon 141 1117 2010 10.1016/j.cell.2010.06.011 Cell signaling by receptor tyrosine kinases
Cell Levine 132 27 2008 10.1016/j.cell.2007.12.018 Autophagy in the pathogenesis of disease
Oncogene Lipinski 18 7873 1999 10.1038/sj.onc.1203244 The retinoblastoma gene family in differentiation and development
Annu. Rev. Cell Dev. Biol. Lobo 23 675 2007 10.1146/annurev.cellbio.22.010305.104154 The biology of cancer stem cells
Nature Lowe 432 307 2004 10.1038/nature03098 Intrinsic tumour suppression
Nature Luebeck 467 1053 2010 10.1038/4671053a Cancer: Genomic evolution of metastasis
J. Clin. Invest. Lu 118 3917 2008 The tumor suppressor gene ARHI regulates autophagy and tumor dormancy in human ovarian cancer cells
Cell Luo 136 823 2009 10.1016/j.cell.2009.02.024 Principles of cancer therapy: Oncogene and non-oncogene addiction
Microcirculation Mac Gabhann 15 715 2008 10.1080/10739680802095964 Systems biology of vascular endothelial growth factors
Dev. Cell Madsen 19 13 2010 10.1016/j.devcel.2010.06.013 Cancer dissemination-Lessons from leukocytes
Nature Maida 461 230 2009 10.1038/nature08283 An RNA-dependent RNA polymerase formed by TERT and the RMRP RNA
Cell Mani 133 704 2008 10.1016/j.cell.2008.03.027 The epithelial-mesenchymal transition generates cells with properties of stem cells
Curr. Mol. Med. Mantovani 10 369 2010 10.2174/156652410791316968 Molecular pathways linking inflammation and cancer
Nature Mantovani 454 436 2008 10.1038/nature07205 Cancer-related inflammation
Cell Massagué 134 215 2008 10.1016/j.cell.2008.07.001 TGFβ in cancer
Proc. Natl. Acad. Sci. USA Masutomi 102 8222 2005 10.1073/pnas.0503095102 The telomerase reverse transcriptase regulates chromatin state and DNA damage responses
Nat. Rev. Cancer Mathew 7 961 2007 10.1038/nrc2254 Role of autophagy in cancer
Future Oncol. McGowan 5 1083 2009 10.2217/fon.09.73 Micrometastatic disease and metastatic outgrowth: clinical issues and experimental approaches
J. Mammary Gland Biol. Neoplasia Micalizzi 15 117 2010 10.1007/s10911-010-9178-9 Epithelial-mesenchymal transition in cancer: parallels between normal development and tumor progression
Genes Dev. Mizushima 21 2861 2007 10.1101/gad.1599207 Autophagy: process and function
Nat. Rev. Cancer Mohamed 6 764 2006 10.1038/nrc1949 Cysteine cathepsins: multifunctional enzymes in cancer
N. Engl. J. Med. Mooi 355 1037 2006 10.1056/NEJMra062285 Oncogene-induced cell senescence-halting on the road to cancer
PLoS ONE Morel 3 e2888 2008 10.1371/journal.pone.0002888 Generation of breast cancer stem cells through epithelial-mesenchymal transition
Nat. Rev. Cancer Mosesson 8 835 2008 10.1038/nrc2521 Derailed endocytosis: an emerging feature of cancer
Adv. Cancer Res. Mougiakakos 107 57 2010 10.1016/S0065-230X(10)07003-X Regulatory T cells in cancer
Nat. Rev. Cancer Murdoch 8 618 2008 10.1038/nrc2444 The role of myeloid cells in the promotion of tumour angiogenesis
Semin. Thromb. Hemost. Nagy 36 321 2010 10.1055/s-0030-1253454 Heterogeneity of the tumor vasculature
APMIS Naumov 116 569 2008 10.1111/j.1600-0463.2008.01213.x Tumor-vascular interactions and tumor dormancy
Nat. Rev. Mol. Cell Biol. Negrini 11 220 2010 10.1038/nrm2858 Genomic instability-an evolving hallmark of cancer
Immunol. Rev. Nelson 222 101 2008 10.1111/j.1600-065X.2008.00614.x The impact of T-cell immunity on ovarian cancer outcomes
Nat. Rev. Cancer Nguyen 9 274 2009 10.1038/nrc2622 Metastasis: from dissemination to organ-specific colonization
Nat. Rev. Neurol. Norden 5 610 2009 10.1038/nrneurol.2009.159 Antiangiogenic therapies for high-grade glioma
Cancer Res. Nyberg 65 3967 2005 10.1158/0008-5472.CAN-04-2427 Endogenous inhibitors of angiogenesis
J. Cell Biol. Okada 171 361 2005 10.1083/jcb.200503165 Merlin/NF-2 mediates contact inhibition of growth by suppressing recruitment of Rac to the plasma membrane
Science Olive 324 1457 2009 10.1126/science.1171362 Inhibition of Hedgehog signaling enhances delivery of chemotherapy in a mouse model of pancreatic cancer
Genes Dev. Olson 23 2152 2009 10.1101/gad.1820109 MicroRNA dynamics in the stages of tumorigenesis correlate with hallmark capabilities of cancer
Cancer Res. O'Reilly 66 1500 2006 10.1158/0008-5472.CAN-05-2925 mTOR inhibition induces upstream receptor tyrosine kinase signaling and activates Akt
J. Immunol. Ostrand-Rosenberg 182 4499 2009 10.4049/jimmunol.0802740 Myeloid-derived suppressor cells: linking inflammation and cancer
Oncogene Pagès 29 1093 2010 10.1038/onc.2009.416 Immune infiltration in human tumors: a prognostic factor that should not be ignored
Trends Pharmacol. Sci. Palermo 29 22 2008 10.1016/j.tips.2007.10.011 Cysteine cathepsin proteases as pharmacological targets in cancer
Nature Park 460 66 2009 10.1038/nature08137 Telomerase modulates Wnt signalling by association with target gene chromatin
Cell Cycle Partanen 8 716 2009 10.4161/cc.8.5.7786 3D view to tumor suppression: Lkb1, polarity and the arrest of oncogenic c-Myc
Nat. Rev. Cancer Pasquale 10 165 2010 10.1038/nrc2806 Eph receptors and ephrins in cancer: bidirectional signalling and beyond
Nucleic Acids Res. Passos 35 7505 2007 10.1093/nar/gkm893 DNA damage in telomeres and mitochondria during cellular senescence: is there a connection?
Microvasc. Res. Patenaude 79 217 2010 10.1016/j.mvr.2010.01.007 Involvement of endothelial progenitor cells in tumor vascularization
Semin. Cancer Biol. Peinado 2011 10.1016/j.semcancer.2011.01.002 The secreted factors responsible for pre-metastatic niche formation: Old sayings and new thoughts
J. Cell Sci. Peinado 117 2827 2004 10.1242/jcs.01145 Snail and E47 repressors of E-cadherin induce distinct invasive and angiogenic properties in vivo
Clin. Transl. Oncol. Perona 8 77 2006 10.1007/s12094-006-0162-1 Cell signalling: growth factors and tyrosine kinase receptors
Exp. Cell Res. Pietras 316 1324 2010 10.1016/j.yexcr.2010.02.045 Hallmarks of cancer: interactions with the tumor stroma
Nat. Rev. Cancer Polyak 9 265 2009 10.1038/nrc2620 Transitions between epithelial and mesenchymal states: acquisition of malignant and stem cell traits
Trends Genet. Polyak 25 30 2009 10.1016/j.tig.2008.10.012 Co-evolution of tumor cells and their microenvironment
Fed. Proc. Potter 17 691 1958 The biochemical approach to the cancer problem
Cell Qian 141 39 2010 10.1016/j.cell.2010.03.014 Macrophage diversity enhances tumor progression and metastasis
Nature Quintana 456 593 2008 10.1038/nature07567 Efficient tumour formation by single human melanoma cells
Eur. J. Cancer Raica 45 1924 2009 10.1016/j.ejca.2009.04.007 Angiogenesis in pre-malignant conditions
Exp. Cell Res. Räsänen 316 2713 2010 10.1016/j.yexcr.2010.04.032 Activation of fibroblasts in cancer stroma
Am. J. Clin. Oncol. Raynaud 33 341 2010 10.1097/COC.0b013e3181b0c4c2 DNA damage repair and telomere length in normal breast, preneoplastic lesions, and invasive cancer
Am. J. Hematol. Raza 85 593 2010 10.1002/ajh.21745 Pericytes and vessel maturation during tumor angiogenesis and metastasis
J. Natl. Cancer Inst. Reitman 102 932 2010 10.1093/jnci/djq187 Isocitrate dehydrogenase 1 and 2 mutations in cancer: alterations at a crossroads of cellular metabolism
Nature Reya 414 105 2001 10.1038/35102167 Stem cells, cancer, and cancer stem cells
Leuk. Res. Ribatti 33 638 2009 10.1016/j.leukres.2008.11.019 Endogenous inhibitors of angiogenesis: a historical review
Nature Ricci-Vitiani 468 824 2010 10.1038/nature09557 Tumour vascularization via endothelial differentiation of glioblastoma stem-like cells
Nat. Rev. Cancer Ruoslahti 2 83 2002 10.1038/nrc724 Specialization of tumour vasculature
J. Cell Biol. Ruoslahti 188 759 2010 10.1083/jcb.200910104 Targeting of drugs and nanoparticles to tumors
J. Cell Biol. Sabeh 185 11 2009 10.1083/jcb.200807195 Protease-dependent versus -independent cancer cell invasion programs: three-dimensional amoeboid movement revisited
Ann. Rev. Pathol. Salk 5 51 2010 10.1146/annurev-pathol-121808-102113 Mutational heterogeneity in human cancers: origin and consequences
Nat. Rev. Mol. Cell Biol. Schäfer 9 628 2008 10.1038/nrm2455 Cancer as an overhealing wound: an old hypothesis revisited
Cancer Metastasis Rev. Schmalhofer 28 151 2009 10.1007/s10555-008-9179-y E-cadherin, beta-catenin, and ZEB1 in malignant progression of cancer
J. Clin. Invest. Semenza 118 3835 2008 Tumor metabolism: cancer cells give and take lactate
Curr. Opin. Genet. Dev. Semenza 20 51 2010 10.1016/j.gde.2009.10.009 HIF-1: upstream and downstream of cancer metabolism
Oncogene Semenza 29 625 2010 10.1038/onc.2009.441 Defining the role of hypoxia-inducible factor 1 in cancer biology and therapeutics
Matrix Biol. Seppinen 27 535 2008 10.1016/j.matbio.2008.03.003 Lack of collagen XVIII accelerates cutaneous wound healing, while overexpression of its endostatin domain leads to delayed healing
Sci. Signal. Shaw 2 pe55 2009 10.1126/scisignal.286pe55 Tumor suppression by LKB1: SIK-ness prevents metastasis
Nat. Rev. Mol. Cell Biol. Shay 1 72 2000 10.1038/35036093 Hayflick, his limit, and cellular ageing
Cell Sherr 102 407 2000 10.1016/S0092-8674(00)00046-5 Cellular senescence: Mitotic clock or culture shock?
Cancer Cell Sherr 2 103 2002 10.1016/S1535-6108(02)00102-2 The RB and p53 pathways in cancer
Science Shields 328 749 2010 10.1126/science.1185837 Induction of lymphoidlike stroma and immune escape by tumors that express the chemokine CCL21
Semin. Cell Dev. Biol. Shimoda 21 19 2010 10.1016/j.semcdb.2009.10.002 Carcinoma-associated fibroblasts are a rate-limiting determinant for tumour progression
Cancer Res. Sigal 60 6788 2000 Oncogenic mutations of the p53 tumor suppressor: the demons of the guardian of the genome
Oncogene Singh 29 4741 2010 10.1038/onc.2010.215 EMT, cancer stem cells and drug resistance: an emerging axis of evil in the war on cancer
Oncogene Sinha 27 Suppl 1 S137 2008 10.1038/onc.2009.51 The autophagy effector Beclin 1: a novel BH3-only protein
Adv. Immunol. Smyth 90 1 2006 10.1016/S0065-2776(06)90001-7 Cancer immunosurveillance and immunoediting: the roles of immunity in suppressing tumor development and shaping tumor immunogenicity
Proc. Natl. Acad. Sci. USA Soda 2011 10.1073/pnas.1016030108 Feature Article: Transdifferentiation of glioblastoma cells into vascular endothelial cells
Curr. Opin. Drug Discov. Devel. Sudarsanam 13 31 2010 Functional consequences of mTOR inhibition
Lancet Oncol. Strauss 11 790 2010 10.1016/S1470-2045(10)70024-3 Transmission of donor melanoma by organ transplantation
Cancer Res. Talmadge 70 5649 2010 10.1158/0008-5472.CAN-10-1040 AACR centennial series: the biology of cancer metastasis: historical perspective
Cell Tammela 140 460 2010 10.1016/j.cell.2010.01.045 Lymphangiogenesis: Molecular mechanisms and future promise
Proc. Natl. Acad. Sci. USA Taube 107 15449 2010 10.1073/pnas.1004900107 Core epithelial-to-mesenchymal transition interactome gene-expression signature is associated with claudin-low and metaplastic breast cancer subtypes
J. Leukoc. Biol. Teng 84 988 2008 10.1189/jlb.1107774 Immune-mediated dormancy: an equilibrium with cancer
Nat. Rev. Mol. Cell Biol. Thiery 7 131 2006 10.1038/nrm1835 Complex networks orchestrate epithelial-mesenchymal transitions
Cell Thiery 139 871 2009 10.1016/j.cell.2009.11.007 Epithelial-mesenchymal transitions in development and disease
Cell Cycle Townson 5 1744 2006 10.4161/cc.5.16.2864 Dormancy of solitary metastatic cells
Endocr. Rev. Turner 24 600 2003 10.1210/er.2002-0008 Angiogenesis in endocrine tumors
Int. J. Cancer Vajdic 125 1747 2009 10.1002/ijc.24439 Cancer incidence and risk factors after solid organ transplantation
Science Vander Heiden 324 1029 2009 10.1126/science.1160809 Understanding the Warburg effect: the metabolic requirements of cell proliferation
BMC Cancer Verhoeff 9 444 2009 10.1186/1471-2407-9-444 Concerns about anti-angiogenic treatment in patients with glioblastoma multiforme
Nature Wang 468 829 2010 10.1038/nature09624 Glioblastoma stem-like cells give rise to tumour endothelium
Science Warburg 123 309 1956 10.1126/science.123.3191.309 On the origin of cancer cells
Science Warburg 124 269 1956 10.1126/science.124.3215.269 On respiratory impairment in cancer cells
Warburg 1930 The Metabolism of Tumours: Investigations from the Kaiser Wilhelm Institute for Biology, Berlin-Dahlem
Cell Death Differ. Wertz 17 14 2010 10.1038/cdd.2009.168 Regulation of death receptor signaling by the ubiquitin system
Curr. Opin. Cell Biol. White 22 212 2010 10.1016/j.ceb.2009.12.008 Role of autophagy in suppression of inflammation and cancer
Clin. Cancer Res. White 15 5308 2009 10.1158/1078-0432.CCR-07-5023 The double-edged sword of autophagy modulation in cancer
Curr. Opin. Cell Biol. Willis 17 617 2005 10.1016/j.ceb.2005.10.001 Life in the balance: how BH3-only proteins induce apoptosis
Physiology (Bethesda) Witsch 25 85 2010 Roles for growth factors in cancer progression
Cancer Res. Wyckoff 67 2649 2007 10.1158/0008-5472.CAN-06-1823 Direct visualization of macrophage-assisted tumor cell intravasation in mammary tumors
Nature Yachida 467 1114 2010 10.1038/nature09515 Distant metastasis occurs late during the genetic evolution of pancreatic cancer
Dev. Cell Yang 14 818 2008 10.1016/j.devcel.2008.05.009 Epithelial-mesenchymal transition: At the crossroads of development and tumor metastasis
Trends Immunol. Yang 31 220 2010 10.1016/j.it.2010.04.002 TGF-beta and immune cells: an important regulatory axis in the tumor microenvironment and progression
Oncogene Yen 29 6409 2010 10.1038/onc.2010.444 Cancer-associated IDH mutations: biomarker and therapeutic opportunities
Cancer Metastasis Rev. Yilmaz 28 15 2009 10.1007/s10555-008-9169-0 EMT, the cytoskeleton, and cancer cell invasion
Oncogene Yuan 27 5497 2008 10.1038/onc.2008.245 PI3K pathway alterations in cancer: variations on a theme
Nat. Rev. Urol. Zee 7 69 2010 10.1038/nrurol.2009.262 Imaging angiogenesis of genitourinary tumors
Oncogene Zhang 23 6193 2004 10.1038/sj.onc.1207834 Disparate effects of telomere attrition on gene expression during replicative senescence of human mammary epithelial cells cultured under different conditions
Genes Dev. Zong 20 1 2006 10.1101/gad.1376506 Necrotic death as a cell fate
Curr. Opin. Oncol. Zumsteg 21 60 2009 10.1097/CCO.0b013e32831bed7e Corrupt policemen: inflammatory cells promote tumor angiogenesis
*원문 PDF 파일 및 링크정보가 존재하지 않을 경우 KISTI DDS 시스템에서 제공하는 원문복사서비스를 사용할 수 있습니다.
출판사/학술단체 등이 한시적으로 특별한 프로모션 또는 일정기간 경과 후 접근을 허용하여, 출판사/학술단체 등의 사이트에서 이용 가능한 논문
Copyright KISTI. All Rights Reserved.
※ AI-Helper는 부적절한 답변을 할 수 있습니다.