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Identifying Schizophrenia and Other Psychoses With Psychological Scales in the General Population

Journal of nervous and mental disease, v.199 no.4, 2011년, pp.230 - 238  

Miettunen, Jouko (*Department of Psychiatry, Oulu University and Oulu University Hospital, Oulu, Finland) ,  Veijola, Juha (†Academy of Finland, Helsinki, Finland) ,  Isohanni, Matti (‡Public Health Genomics Unit, National Institute for Health and Welfare, Helsinki, Finland) ,  Paunio, Tiina (§Department of Psychiatry, Helsinki University Central Hospital, Helsinki, Finland) ,  Freimer, Nelson (¶Center for Neurobehavioral Genetics, Semen Institute for Neuroscience and Human Behavior, UCLA, Los Angeles, CA) ,  Jääskeläinen, Erika (∥Institute of Health Sciences, University of Oulu, Oulu, Finland) ,  Taanila, Anja (**Unit of General Practice, Oulu University Hospital, Oulu, Finland) ,  Ekelund, Jesper (††Department of Mental Health and Substance Abuse Services, National Institute for Health and Welfare, Helsinki, Finland) ,  Järvelin, Marjo-Riitta (‡‡Department of Epidemiology and Public Health, Imperial College London, United Kingdom) ,  Peltonen, Leena (§§Lifecourse and Services Department, National Institute for Health and Welfare, Oulu, Finland) ,  Joukamaa, Matti (¶¶Biocen) ,  Lichtermann, Dirk

Abstract

We study the predictive power and associations of several psychopathology and temperament scales with respect to schizophrenia and other psychotic disorders. Measures of psychopathology (Physical and Social Anhedonia Scales, Perceptual Aberration Scale, Hypomanic Personality Scale, Bipolar II Scale, and Schizoidia Scale) and the Temperament and Character Inventory were included in the 31-year follow-up of the prospective Northern Finland 1966 birth cohort (N = 4926). The Perceptual Aberration Scale was the best scale for concurrent validity in psychoses, and also the best psychopathology scale in terms of discriminant validity. Participants scoring high in hypomanic personality were at the highest risk for developing psychosis during the 11-year follow-up. Harm avoidance was a dominant temperament dimension in individuals with psychosis compared with participants without psychiatric diagnoses. These scales are useful as vulnerability markers in studying psychoses.

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