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[해외논문] Retinyl retinoate, a novel hybrid vitamin derivative, improves photoaged skin: a double‐blind, randomized‐controlled trial

Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Soci, v.17 no.3, 2011년, pp.380 - 385  

Kim, H. (Department of Biotechnology, Yonsei University, Seoul, Korea) ,  Koh, J. (Department of Skin Research Center, Dermapro Co. Ltd, Seoul, Korea) ,  Baek, J. (Department of Skin Research Center, Dermapro Co. Ltd, Seoul, Korea) ,  Seo, Y. (Department of Skin Research Center, Dermapro Co. Ltd, Seoul, Korea) ,  Kim, B. (Department of Skin Science and Cosmetics, Enprani Co. Ltd, Inchon, Korea) ,  Kim, J. (Department of Skin Science and Cosmetics, Enprani Co. Ltd, Inchon, Korea) ,  Lee, J. (Department of Skin Science and Cosmetics, Enprani Co. Ltd, Inchon, Korea) ,  Ryoo, H. (Department of Skin Science and Cosmetics, Enprani Co. Ltd, Inchon, Korea) ,  Jung, H. (Department of Biotechnology, Yonsei University, Seoul, Korea)

Abstract AI-Helper 아이콘AI-Helper

Background: All‐trans‐retinoic acid (RA) and all‐trans‐retinol (ROL) are not widely used as anti‐wrinkle agents due to their irritancy and photo‐stability, respectively. Therefore, the safety and photo‐stability in the development of RA or ROL derivatives h...

주제어

참고문헌 (19)

  1. mechanisms and repair Jessica HR 1 55 2006 Photoaging 

  2. Tsukahara,, Takema,, Fujimura,, Moriwaki,, Kitahara,, Imayama,, Imokawa,. All‐trans retinoic acid promotes the repair of tortuosity of elastic fibres in rat skin. British journal of dermatology : BJD, vol.140, no.6, 1048-1053.

  3. the effects of tretinoin Green LJ 97 11 1993 Photoaging and the skin 

  4. GILCHREST, B.A.. A review of skin ageing and its medical therapy. British journal of dermatology : BJD, vol.135, no.6, 867-875.

  5. pathogenesis, prevention, and treatment Kang S 643 17 2001 Photoaging 

  6. Fisher, Gary J., Wang, ZengQuan, Datta, Subhash C., Varani, James, Kang, Sewon, Voorhees, John J.. Pathophysiology of Premature Skin Aging Induced by Ultraviolet Light. The New England journal of medicine, vol.337, no.20, 1419-1429.

  7. J Am Acad Dermatol Weiss JS 169 19 2 1998 Topical tretinoin in the treatment of aging skin 

  8. its prevention and repair Kligman LH 215 3 1986 The nature of photoaging 

  9. Chen, Simon, Kiss, Ilona, Tramposch, Kenneth M. Effects of All-Trans Retinoic Acid on UVB-Irradiated and Non-Irradiated Hairless Mouse Skin. The Journal of investigative dermatology, vol.98, no.2, 248-254.

  10. Bryce, Graeme F, Bogdan, Nancy J, Brown, Corinne C. Retinoic Acids Promote the Repair of the Dermal Damage and the Effacement of Wrinkles in the UVB-Irradiated Hairles Mouse. The Journal of investigative dermatology, vol.91, no.2, 175-180.

  11. Nau, Heinz. Embryotoxicity and Teratogenicity of Topical Retinoic Acid. Skin pharmacology : the official journal of the Skin Pharmacology Society, vol.6, no.suppl1, 35-44.

  12. Kim, Bae-Hwan, Lee, Yong-Soon, Kang, Kyung-Sun. The mechanism of retinol-induced irritation and its application to anti-irritant development. Toxicology letters, vol.146, no.1, 65-73.

  13. Kang, Sewon, Duell, Elizabeth A., Fisher, Gary J., Datta, Subhash C., Wang, Zeng-Quan, Reddy, Ambati P., Tavakkol, Amir, Yi, Jong Y., Griffiths, Christopher E.M., Elder, James T., Voorhees, John J.. Application of Retinol to Human Skin In Vivo Induces Epidermal Hyperplasia and Cellular Retinoid Binding Proteins Characteristic of Retinoic Acid but Without Measurable Retinoic Acid Levels or Irritation. The Journal of investigative dermatology, vol.105, no.4, 549-556.

  14. stability, toxicity, and activity Han HS 3839 11 2003 Efficacy validation of synthesized retinol derivatives in vitro 

  15. Brisaert, M, Plaizier-Vercammen, J. Investigation on the photostability of a tretinoin lotion and stabilization with additives. International journal of pharmaceutics, vol.199, no.1, 49-57.

  16. Kim, H., Kim, B., Kim, H., Um, S., Lee, J., Ryoo, H., Jung, H.. Synthesis and in vitro biological activity of retinyl retinoate, a novel hybrid retinoid derivative. Bioorganic & medicinal chemistry, vol.16, no.12, 6387-6393.

  17. a randomized controlled trial Kim H 497 162 2010 Improvement in skin wrinkles from the use of photostable retinyl retinoate 

  18. De Paepe, K., Lagarde, J.-M., Gall, Y., Roseeuw, D., Rogiers, V.. Microrelief of the skin using a light transmission method. Archives of dermatological research, vol.292, no.10, 500-510.

  19. Grove, Gary L., Grove, Mary Jo, Leyden, James J., Lufrano, Laura, Schwab, Barry, Perry, Barbara H., Thorne, E. George. Skin replica analysis of photodamaged skin after therapy with tretinoin emollient cream. Journal of the American Academy of Dermatology, vol.25, no.2, 231-237.

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