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Abstract ▼ AI-Helper

Previous studies have been suggested the association of ACTN-3 gene polymorphism with physical fitness. The purpose of this study is the analysis of ACTN-3 gene polymorphism in Korean athletes. Subject were divided into two groups as elite athletes (N=32) and junior level athletes (N=73). Genomic DN...

Previous studies have been suggested the association of ACTN-3 gene polymorphism with physical fitness. The purpose of this study is the analysis of ACTN-3 gene polymorphism in Korean athletes. Subject were divided into two groups as elite athletes (N=32) and junior level athletes (N=73). Genomic DNA was isolated from peripheral blood using the phenol-chloroform method. Genotyping for the identification of the R577X mutation in the ACTN-3 gene was performed by an allelic discrimination assay with PCR. Sprinter group of elite athletes showed 5 XX type, 2 RR type, and 6 RX type. Total numbers of junior athletes showed RR type of 41.1%, RX type of 45.2%, and XX type of 13.7%. Korean athletes showed a low tendency of RR type percentage in ACTN-3 gene polymorphism. Elite athletes group showed no significant of specificity for detailed events. But junior athletes group showed a significant of specificity for detailed events with a higher percentage of RR type compared to elite group.

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