[논문]Skeletal muscle mass to visceral fat area ratio is associated with metabolic syndrome and arterial stiffness: The Korean Sarcopenic Obesity Study (KSOS)

Kim, Tae Nyun; Park, Man Sik; Lim, Kang Il; Yang, Sae Jeong; Yoo, Hye Jin; Kang, Hyun Joo; Song, Wook; Seo, Ji A.; Kim, Sin Gon; Kim, Nan Hee; Baik, Sei Hyun; Choi, Dong Seop; Choi, Kyung Mook

doi:10.1016/j.diabres.2011.06.013

Skeletal muscle mass to visceral fat area ratio is associated with metabolic syndrome and arterial stiffness: The Korean Sarcopenic Obesity Study (KSOS)

Diabetes research and clinical practice, v.93 no.2, 2011년, pp.285 - 291

Kim, Tae Nyun (Division of Endocrinology and Metabolism, Department of Internal Medicine, College of Medicine, Korea University, Seoul 152-050, Republic of Korea) , Park, Man Sik (Department of Statistics, College of Natural Sciences, Sungshin Women's University, Seoul, Republic of Korea) , Lim, Kang Il (Division of Endocrinology and Metabolism, Department of Internal Medicine, College of Medicine, Korea University, Seoul 152-050, Republic of Korea) , Yang, Sae Jeong (Division of Endocrinology and Metabolism, Department of Internal Medicine, College of Medicine, Korea University, Seoul 152-050, Republic of Korea) , Yoo, Hye Jin (Division of Endocrinology and Metabolism, Department of Internal Medicine, College of Medicine, Korea University, Seoul 152-050, Republic of Korea) , Kang, Hyun Joo (Sports Medicine, Division of Physical Education, Soonchunhyang University, A-San, Republic of Korea) , Song, Wook (Health and Exercise Science Laboratory, Institute of Sports Science, Department of Physical Education, Seoul National University, Seoul, Republic of Korea) , Seo, Ji A. (Division of Endocrinology and Meta) , Kim, Sin Gon , Kim, Nan Hee , Baik, Sei Hyun , Choi, Dong Seop , Choi, Kyung Mook

Abstract ▼ AI-Helper

Abstract Aims Sarcopenia measured as appendicular skeletal muscle mass (ASM), and central obesity measured as visceral fat area (VFA) may act synergistically to influence metabolic syndrome and atherosclerosis. However, several previous studies reported that metabolic risk is higher in non-sarcopenic obesity groups than in sarcopenic obesity groups because of the close relationship between muscle mass and body fat. We investigated the association of the ASM to VFA ratio, which we have termed the muscle-to-fat ratio (MFR), with metabolic syndrome and arterial stiffness. Methods This study was performed in 526 apparently healthy adults enrolled in the Korean Sarcopenic Obesity Study, an ongoing prospective observational cohort study. ASM was evaluated with dual energy X-ray absorptiometry and VFA with computed tomography. Arterial stiffness was measured using brachial-ankle pulse wave velocity (baPWV). Results MFR was significantly associated with waist circumference, blood pressure, lipid profiles, glucose and baPWV. By multiple logistic regression analysis, the odds ratio for metabolic syndrome was 5.43 (lowest versus highest tertile of MFR, 95% confidence interval, 2.56–13.34). Multiple stepwise regression analysis showed that MFR was an independent determinant of baPWV (R 2 =0.57). Conclusions MFR, a new index of sarcopenic obesity, showed an independent negative association with metabolic syndrome and arterial stiffness.

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참고문헌 (35)

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Skeletal muscle mass to visceral fat area ratio is associated with metabolic syndrome and arterial stiffness: The Korean Sarcopenic Obesity Study (KSOS)

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Skeletal muscle mass to visceral fat area ratio is associated with metabolic syndrome and arterial stiffness: The Korean Sarcopenic Obesity Study (KSOS)

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