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RP‐HPLC‐DAD for simultaneous estimation of mahanine and mahanimbine in Murraya koenigii

Biomedical chromatography : BMC, v.25 no.9, 2011년, pp.959 - 962  

Pandit, Subrata (School of Natural Product Studies, Department of Pharmaceutical Technology, Jadavpur University, Kolkata 700032, India) ,  Kumar, Mythies (School of Natural Product Studies, Department of Pharmaceutical Technology, Jadavpur University, Kolkata 700032, India) ,  Ponnusankar, S. (School of Natural Product Studies, Department of Pharmaceutical Technology, Jadavpur University, Kolkata 700032, India) ,  Pal, B. C. (School of Natural Product Studies, Department of Pharmaceutical Technology, Jadavpur University, Kolkata 700032, India) ,  Mukherjee, Pulok K.

Abstract AI-Helper 아이콘AI-Helper

AbstractMurraya koenigii leaves (Rutaceae) are widely used as food condiments in various food preparations in India. They possess a wide range of biological activities including antioxidant, antibacterial, anticancer, hypoglycemic and hypolipidemic activity. A rapid reverse‐phase high‐pe...

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참고문헌 (16)

  1. Biswas A , Bhattacharya S , Dasgupta S , Kundu R , Roy SS , Pal BC and Bhattacharya S . Insulin resistance due to lipid‐induced signaling defects could be prevented by Mahanine . Molecular and Cellular Biochemistry 2010 ; 336 : 97 – 107 . 

  2. Dineshkumar B , Mitra A and Mahadevappa M . Antidiabetic and hypolipidemic effects of mahanimbine (carbazole alkaloid) from Murraya koenigii (rutaceae) leaves . International Journal of Phytomedicine 2010 ; 2 : 22 – 30 . 

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  6. ICH . Q2B. Validation of Analytical Procedure: Methodology . International Conference on Harmonization : Geneva , 1996 . 

  7. ICH . Q2A. Validation of Analytical Procedures: Text and Methodology . International Conference on Harmonization : Geneva , 2005 . 

  8. Iyer D and Devi PU . Phyto‐pharmacology of Murraya koenigii (L.) . Pharmacognosy Reviews 2008 ; 2 : 180 – 184 . 

  9. Kumar NS , Mukherjee PK , Bhadra S , Saha BP and Pal BC . Acetylcholinesterase inhibitory potential of a carbazole alkaloid, mahanimbine, from Murraya koenigii . Phytotherapy Research 2010 ; 24 : 629 – 631 . 

  10. Kumar V , Mukherjee K , Kumar S , Mal M and Mukherjee PK . Validation of HPTLC method for the analysis of taraxerol in Clitoria ternatea . Phytochemical Analysis 2008 ; 19 : 244 – 250 . 

  11. Mukherjee PK . Quality Control on Herbal Drugs , 1st edn . Business Horizons : New Delhi , 2002 . 

  12. Mukherjee PK , Rai S , Bhattacharya S , Wahile A and Saha BP . Marker analysis of polyherbal formulation, Triphala—a well known Indian traditional medicine . Indian Journal of Traditional Knowledge 2008 ; 7 : 379 – 383 . 

  13. Rai S , Mukherjee K , Mal M , Wahile A , Saha BP and Mukherjee PK . Determination of 6‐gingerol in ginger ( Zingiber officinale ) using high‐performance thin‐layer chromatography . Journal of Separation Science 2006 ; 29 : 2292 – 2295 . 

  14. Ramsewak RS , Nair MG , Strasburg GM , Witt DLD and Nitiss JL . Biologically active carbazoles alkaloids from Murraya koenigii . Journal of Agricultural and Food Chemistry 1999 ; 47 : 444 – 447 . 

  15. Roy MK , Thalang VN , Trakoontivakorn G and Nakahara K . Mahanine, a carbazole alkaloid from Micromelum minutum , inhibits cell growth and induces apoptosis in U937 cells through a mitochondrial dependent pathway . British Journal of Pharmacology 2005 ; 145 : 145 – 155 . 

  16. Sinha S , Pal BC , Jagadeesh S , Banerjee PP , Bandyopadhyay A and Bhattacharya S. Mahanine inhibits growth and induces apoptosis in prostate cancer cells through the deactivation of Akt and activation of caspases . Prostate 2006 ; 66 : 1257 – 1265 . 

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