[논문]Multiple extramedullary relapses without bone marrow involvement after second allogeneic hematopoietic stem cell transplantation for acute myeloid leukemia

Yoo, Sang Woo; Chung, Eun Jin; Kim, Sun Young; Ko, Jeong Hee; Baek, Hey Sung; Lee, Hyun Ju; Oh, Sung Hee; Jeon, Seok Cheol; Lee, Woong Soo; Park, Chan Kum; Lee, Chul Hoon

doi:10.1111/j.1399-3046.2011.01546.x

Multiple extramedullary relapses without bone marrow involvement after second allogeneic hematopoietic stem cell transplantation for acute myeloid leukemia

Pediatric transplantation, v.16 no.4, 2012년, pp.E125 - E129

Yoo, Sang Woo (Department of Pediatrics, Hanyang University Medical Center, Seoul) , Chung, Eun Jin (Department of Pediatrics, Hanyang University Medical Center, Seoul) , Kim, Sun Young (Department of Pediatrics, Hanyang University Medical Center, Seoul) , Ko, Jeong Hee (Department of Pediatrics, Hanyang University Medical Center, Seoul) , Baek, Hey Sung (Department of Pediatrics, Hanyang University Medical Center, Seoul) , Lee, Hyun Ju (Department of Pediatrics, Hanyang University Medical Center, Seoul) , Oh, Sung Hee (Department of Pediatrics, Hanyang University Medical Center, Seoul) , Jeon, Seok Cheol (Department of Radiology, Hanyang University Medical College, Seoul) , Lee, Woong Soo (Department of Laboratory Medicine, Hanyang University Hospital, Seoul) , Park, Chan Kum (Department of Pathology, Hanyang University Medical College, Seoul, Korea) , Lee, Chul Hoon (College of Pharmacy, Hanyang University, Ansan, Korea)

Abstract ▼ AI-Helper

Yoo SW, Chung EJ, Kim SY, Ko JH, Baek HS, Lee HJ, Oh SH, Jeon SC, Lee WS, Park CK, Lee CH. Multiple extramedullary relapses without bone marrow involvement after second allogeneic hematopoietic stem cell transplantation for acute myeloid leukemia.Abstract: EMR without BM involvement after allogeneic HSCT is extremely rare, especially in children; only a few cases have been reported. A two‐yr‐old boy was diagnosed with AML (M4) and underwent allogeneic HSCT in first complete remission with BM from HLA‐matched unrelated donor without GVHD. Four yr later, he had a BM relapse and after induction and consolidation chemotherapy, he received a second HSCT from an unrelated donor using peripheral blood stem cells. His second post‐transplant course was complicated by extensive chronic GVHD involving the skin, oral cavity, and lungs, which was treated with tacrolimus and corticosteroid. Two yr later, he noticed a mild swelling in the right cheek area. The BM showed a complete remission marrow and a soft tissue biopsy was compatible with granulocytic sarcoma. PET‐CT showed multifocal bone involvements. He received chemotherapy, and the chloromas decreased in size. We report a case of diffuse EMR of AML without BM involvement after a second allogeneic HSCT.

주제어

참고문헌 (17)

1 Wayne AS , Baird K , Egeler RM . Hematopoietic stem cell transplantation for leukemia . Pediatr Clin North Am 2010 : 57 : 1 – 25 .

상세보기
2 Jenq RR , Van Den Brink MR . Allogeneic haematopoietic stem cell transplantation: Individualized stem cell and immune therapy of cancer . Nat Rev Cancer 2010 : 10 : 213 – 221 .

상세보기
3 Choi SW , Levine JE , Ferrara JL . Pathogenesis and management of graft‐versus‐host disease . Immunol Allergy Clin North Am 2010 : 30 : 75 – 101 .

상세보기
4 Sprangers B , Fevery S , Van Wijmeersch B , et？al. Can graft‐versus‐leukemia reactivity be dissociated from graft‐versus‐host disease? Front Biosci 2007 : 12 : 4568 – 4594 .
5 Lai YH , Chang CS , Liu YC , et？al. Postallogeneic hematopoietic stem cell transplantation relapse of acute myeloid leukemia presenting with salivary gland myelosarcoma . Ann Hematol 2010 : 89 : 631 – 633 .
6 Firas AS , Demeckova E , Bojtarova E , et？al. Isolated extra‐medullary relapse of acute leukemia following allogeneic bone marrow transplantation . Bratisl Lek Listy 2008 : 9 : 358 – 361 .
7 Au WY , Kwong YL , Lie AK , et？al. Extra‐medullary relapse of leukemia following allogeneic bone marrow transplantation . Hematol Oncol 1999 : 17 : 45 – 52 .

상세보기
8 Lee JH , Choi SJ , Lee JH , et？al. Anti‐leukemic effect of graft‐versus‐host disease on bone marrow and extramedullary relapses in acute leukemia . Haematologica 2005 : 90 : 1380 – 1388 .

상세보기
9 Maeng H , Cheong JW , Lee ST , et？al. Isolated extramedullary relapse of acute myelogenous leukemia as a uterine granulocytic sarcoma in an allogeneic hematopoietic stem cell transplantation recipient . Yonsei Med J 2004 : 45 : 330 – 333 .

상세보기
10 Ando T , Mitani N , Matsui K , et？al. Recurrent extramedullary relapse of acute myelogenous leukemia after allogeneic hematopoietic stem cell transplantation in a patient with the chromosomal abnormality t(8;21) and CD56‐positivity . Int J Hematol 2009 : 90 : 374 – 377 .

상세보기
11 Chong G , Byrnes G , Szer J , et？al. Extramedullary relapse after allogeneic bone marrow transplantation for haematological malignancy . Bone Marrow Transplant 2000 : 26 : 1011 – 1015 .

상세보기
12 Lee KH , Lee JH , Choi SJ , et？al. Bone marrow vs extramedullary relapse of acute leukemia after allogeneic hematopoietic cell transplantation: Risk factors and clinical course . Bone Marrow Transplant 2003 : 32 : 835 – 842 .

상세보기
13 Chao MM , Kontny U , Brink I , et？al. Extramedullary relapse of therapy‐related myelodysplastic syndrome after donor leukocyte infusion . Ann Hematol 2008 : 87 : 165 – 166 .
14 Bekassy AN , Hermans J , Gorin NC , et？al. Granulocytic sarcoma after allogeneic bone marrow transplantation: A retrospective European multicenter survey. Acute and Chronic Leukemia Working Parties of the European Group for Blood and Marrow Transplantation . Bone Marrow Transplant 1996 : 17 : 801 – 808 .
15 Ferri E , Minotto C , Ianniello F , et？al. Maxillo‐ethmoidal chloroma in acute myeloid leukaemia: Case report . Acta Otorhinolaryngol Ital 2005 : 25 : 195 – 199 .

상세보기
16 Kikushige Y , Takase K , Sata K , et？al. Repeated relapses of acute myelogenous leukemia in the isolated extramedullary sites following allogeneic bone marrow transplantations . Intern Med 2007 : 46 : 1011 – 1014 .

상세보기
17 Owonikoko T , Agha M , Balassanian R , et？al. Gemtuzumab therapy for isolated extramedullary AML relapse following allogeneic stem‐cell transplant . Nat Clin Pract Oncol 2007 : 4 : 491 – 495 .

상세보기

내보내기 구분	파일저장 인쇄 메일전송
구성항목	기본정보 상세정보 관리번호, 논문명, 저널/프로시딩명, 저자 , 발행년, 권, 호, 시작페이지, 끝페이지, 발행기관 관리번호, 논문명, 대등논문명, 저자 , 저널/프로시딩명, 발행기관, 발행년, 발행언어, 권, 호, 시작페이지, 끝페이지, ISBN, ISSN, 주제분야, 키워드, 초록(한글), 초록(영문), 저자(소속기관)
저장형식	Text(ASCII format) Excel format RefWorks Direct Export RIS format (for Reference Manager, ProCite, EndNote), Scholar's Aids, Mendeley
메일정보	받는사람 (필수) @ 보내는사람 (선택) @ 제목 내용 KISTI 검색결과 이메일 서비스
안내	총 건의 자료가 검색되었습니다. 다운받으실 자료의 인덱스를 입력하세요. (1-10,000) 검색결과의 순서대로 최대 10,000건 까지 다운로드가 가능합니다. 데이타가 많을 경우 속도가 느려질 수 있습니다.(최대 2~3분 소요) 다운로드 파일은 UTF-8 형태로 저장됩니다. 파일의 내용이 제대로 보이지 않을실 때는 웹브라우저 상단의 보기 -> 인코딩 -> 자동선택 여부를 확인하십시오. ~ Text(ASCII format) Excel format

연합인증

Multiple extramedullary relapses without bone marrow involvement after second allogeneic hematopoietic stem cell transplantation for acute myeloid leukemia

Abstract ▼ AI-Helper

주제어

참고문헌 (17)

이 논문을 인용한 문헌

관련 콘텐츠

원문 URL 링크

이 논문과 함께 이용한 콘텐츠

AI-Helper ※ AI-Helper는 오픈소스 모델을 사용합니다.

선택된 텍스트