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Proceedings of the National Academy of Sciences of the United States of America, v.109 no.47, 2012년, pp.19408 - 19413
Lockwood, William W. (Cancer Biology and Genetics Section, Cancer Genetics Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD 20892) , Zejnullahu, Kreshnik , Bradner, James E. (Cancer Biology and Genetics Section, Cancer Genetics Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD 20892) , Varmus, Harold
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Bromodomain and extra terminal domain (BET) proteins function as epigenetic signaling factors that associate with acetylated histones and facilitate transcription of target genes. Inhibitors targeting the activity of BET proteins have shown potent antiproliferative effects in hematological cancers ...
Kouzarides, Tony. Chromatin Modifications and Their Function. Cell, vol.128, no.4, 693-705.
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