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Bioactives from probiotics for dermal health: functions and benefits

Journal of applied microbiology, v.114 no.5, 2013년, pp.1241 - 1253  

Lew, L.‐C. (School of Industrial Technology, Universiti Sains Malaysia, Penang, Malaysia) ,  Liong, M.‐T. (School of Industrial Technology, Universiti Sains Malaysia, Penang, Malaysia)

Abstract

SummaryProbiotics have been extensively reviewed for decades, emphasizing on improving general gut health. Recently, more studies showed that probiotics may exert other health‐promoting effects beyond gut well‐being, attributed to the rise of the gut–brain axis correlations. Some of these new benefits include skin health such as improving atopic eczema, atopic dermatitis, healing of burn and scars, skin‐rejuvenating properties and improving skin innate immunity. Increasing evidence has also showed that bacterial compounds such as cell wall fragments, their metabolites and dead bacteria can elicit certain immune responses on the skin and improve skin barrier functions. This review aimed to underline the mechanisms or the exact compounds underlying the benefits of bacterial extract on the skin based on evidences from in vivo and in vitro studies. This review could be of help in screening of probiotic strains with potential dermal enhancing properties for topical applications.

주제어

참고문헌 (98)

  1. Abad , C.L. and Safdar , N. ( 2009 ) The role of lactobacillus probiotics in the treatment or prevention of urogenital infections–a systematic review . J Chemother 21 , 243 – 252 . 

  2. Akiyama , H. , Yamasaki , O. , Tada , J. and Arata , J. ( 1999 ) Effects of acetic acid on biofilms formed by Staphylococcus aureus . Arch Dermatol Res 291 , 570 – 573 . 

  3. Anilkumar , T.V. , Muhamed , J. , Jose , A. , Jyothi , A. , Mohanan , P.V. and Krishnan , L.K. ( 2011 ) Advantages of hyaluronic acid as a component of fibrin sheet for care of acute wound . Biologicals 39 , 81 – 88 . 

  4. Arck , P. , Handjiski , B. , Hagen , E. , Pincus , M. , Bruenahl , C. , Bienenstock , J. and Paus , R. ( 2010 ) Is there a ‘gut‐brain‐skin axis’? Exp Dermatol 19 , 401 – 405 . 

  5. Berardesca , E. , Barbareschi , M. , Veraldi , S. and Pimpinelli , N. ( 2001 ) Evaluation of efficacy of a skin lipid mixture in patients with irritant contact dermatitis, allergic contact dermatitis or atopic dermatitis: a multicenter study . Contact Dermatitis 45 , 280 – 285 . 

  6. Cabeen , M.T. and Jacobs‐Wagner , C. ( 2005 ) Bacterial cell shape . Nat Rev Microbiol 3 , 601 – 610 . 

  7. Caramia , G. and Silvi , S. ( 2011 ) Probiotics: from the ancient wisdom to the actual therapeutical and nutraceutical perspective . In Probiotic Bacteria and Enteric Infections: Cytoprotection by Probiotic Bacteria ed. Malago , J.J. , Koninkx , J.F.J.G. and Marinsek‐Logar , R. pp. 476 . London : Springer . 

  8. Chien , L.‐J. and Lee , C.‐K. ( 2007 ) Hyaluronic acid production by recombinant Lactococcus lactis . Appl Microbiol Biotechnol 77 , 339 – 346 . 

  9. Choi , M.J. and Maibach , H.I. ( 2003 ) Role of ceramides in skin stress: ultraviolet light, tape stripping and crowding . Exog Dermatol 2 , 286 – 294 . 

  10. Chong , B.F. , Blank , L.M. , McLaughlin , R. and Nielsen , L.K. ( 2005 ) Microbial hyaluronic acid production . Appl Microbiol Biotechnol 66 , 341 – 351 . 

  11. Daum , R.S. ( 2007 ) Skin and soft‐tissue infections caused by methicillin‐resistant Staphylococcus aureus . N Engl J Med 357 , 380 – 390 . 

  12. De Kimpe , S.J. , Kengatharan , M. , Thiemermann , C. and Vane , J.R. ( 1995 ) The cell wall components peptidoglycan and lipoteichoic acid from Staphylococcus aureus act in synergy to cause shock and multiple organ failure . Proc Natl Acad Sci USA 92 , 10359 – 10363 . 

  13. Di Marzio , L. , Cinque , B. , De Simone , C. and Cifone , M.G. ( 1999 ) Effect of the lactic acid bacterium Streptococcus thermophilus on ceramide levels in human keratinocytes in vitro and stratum corneum in vivo . J Invest Dermatol 113 , 98 – 106 . 

  14. Di Marzio , L. , Russo , F.P. , D'Alo , S. , Biordi , L. , Ulisse , S. , Amicosante , G. , De Simone , C. and Cifone , M.G. ( 2001 ) Apoptotic effects of selected strains of lactic acid bacteria on a human T leukemia cell line are associated with bacterial arginine deiminase and/or sphingomyelinase activities . Nutr Cancer 40 , 185 – 196 . 

  15. Di Marzio , L. , Centi , C. , Cinque , B. , Masci , S. , Giuliani , M. , Arcieri , A. , Zicari , L. , De Simone , C. et?al . ( 2003 ) Effect of the lactic acid bacterium Streptococcus thermophilus on stratum corneum ceramide levels and signs and symptoms of atopic dermatitis patients . Exp Dermatol 12 , 615 – 620 . 

  16. Ditre , C.M. , Griffin , T.D. , Murphy , G.F. , Sueki , H. , Telegan , B. , Johnson , W.C. , Yu , R.J. and Van Scott , E.J. ( 1996 ) Effects of alpha‐hydroxy acids on photoaged skin: a pilot clinical, histologic, and ultrastructural study . J Am Acad Dermatol 34 , 187 – 195 . 

  17. Doern , G.V. , Jones , R.N. , Pfaller , M.A. , Kugler , K.C. and Beach , M.L. ( 1999 ) Bacterial pathogens isolated from patients with skin and soft tissue infections: frequency of occurrence and antimicrobial susceptibility patterns from the SENTRY Antimicrobial Surveillance Program (United States and Canada, 1997) . Diagn Microbiol Infect Dis 34 , 65 – 72 . 

  18. Dziarski , R. ( 2003 ) Recognition of bacterial peptidoglycan by the innate immune system . Cell Mol Life Sci 60 , 1793 – 1804 . 

  19. Dziarski , R. and Gupta , D. ( 2005 ) Peptidoglycan recognition in innate immunity . J Endotoxin Res 11 , 304 – 310 . 

  20. Eifert , J.D. , Hackney , C.R. , Pierson , M.D. , Duncan , S.E. and Eigel , W.N. ( 1997 ) Acetic, lactic, and hydrochloric acid effects on Staphylococcus aureus 196E growth based on a predictive model . J Food Sci 62 , 174 – 178 . 

  21. Fournier , B. and Philpott , D.J. ( 2005 ) Recognition of Staphylococcus aureus by the innate immune system . Clin Microbiol Rev 18 , 521 – 540 . 

  22. Garg , T. , Ramam , M. , Pasricha , J.S. and Verma , K.K. ( 2002 ) Long term topical application of lactic acid/lactate lotion as a preventive treatment for acne vulgaris . Indian J Dermatol Venereol Leprol 68 , 137 – 139 . 

  23. Gariboldi , S. , Palazzo , M. , Zanobbio , L. , Selleri , S. , Sommariva , M. , Sfondrini , L. , Cavicchini , S. , Balsari , A. et?al . ( 2008 ) Low molecular weight hyaluronic acid increases the self‐defense of skin epithelium by induction of beta‐defensin 2 via TLR2 and TLR4 . J Immunol 181 , 2103 – 2110 . 

  24. Ghuysen , J.M. ( 1968 ) Use of bacteriolytic enzymes in determination of wall structure and their role in cell metabolism . Bacteriol Rev 32 , 425 – 464 . 

  25. Guarner , F. and Schaafsma , G.J. ( 1998 ) Probiotics . Int J Food Microbiol 39 , 237 – 238 . 

  26. Gueniche , A. , Bastien , P. , Ovigne , J.M. , Kermici , M. , Courchay , G. , Chevalier , V. , Breton , L. and Castiel‐Higounenc , I. ( 2010 ) Bifidobacterium longum lysate, a new ingredient for reactive skin . Exp Dermatol 19 , e1 – e8 . 

  27. Hansson , C. and Faergemann , J. ( 1995 ) The effect of antiseptic solutions on microorganisms in venous leg ulcers . Acta Derm Venereol 75 , 31 – 33 . 

  28. Harder , J. and Schroder , J.M. ( 2005 ) Antimicrobial peptides in human skin . Chem Immunol Allergy 86 , 22 – 41 . 

  29. Hoang , B.X. , Shaw , G. , Pham , P. and Levine , S.A. ( 2010 ) Lactobacillus rhamnosus cell lysate in the management of resistant childhood atopic eczema . Inflamm Allergy Drug Targets 9 , 192 – 196 . 

  30. Huseini , H.F. , Rahimzadeh , G. , Fazeli , M.R. , Mehrazma , M. and Salehi , M. ( 2012 ) Evaluation of wound healing activities of kefir products . Burns 38 , 719 – 723 . 

  31. Iordache , F. , Iordache , C. , Chifiriuc , M.C. , Bleotu , C. , Pavel , M. , Smarandache , D. , Sasarman , E. , Laza , V. et?al . ( 2008 ) Antimicrobial and immunomodulatory activity of some probiotic fractions with potential clinical application . Arch Zootc 11 , 41 – 51 . 

  32. Izawa , N. , Hanamizu , T. , Iizuka , R. , Sone , T. , Mizukoshi , H. , Kimura , K. and Chiba , K. ( 2009 ) Streptococcus thermophilus produces exopolysaccharides including hyaluronic acid . J Biosci Bioeng 107 , 119 – 123 . 

  33. Izawa , N. , Serata , M. , Sone , T. , Omasa , T. and Ohtake , H. ( 2011 ) Hyaluronic acid production by recombinant Streptococcus thermophilus . J Biosci Bioeng 111 , 665 – 670 . 

  34. Jay , J.M. ( 1982 ) Antimicrobial properties of diacetyl . Appl Environ Microbiol 44 , 525 – 532 . 

  35. Jensen , J.M. , Folster‐Holst , R. , Baranowsky , A. , Schunck , M. , Winoto‐Morbach , S. , Neumann , C. , Schutze , S. and Proksch , E. ( 2004 ) Impaired sphingomyelinase activity and epidermal differentiation in atopic dermatitis . J Invest Dermatol 122 , 1423 – 1431 . 

  36. Jensen , J.M. , Forl , M. , Winoto‐Morbach , S. , Seite , S. , Schunck , M. , Proksch , E. and Schutze , S. ( 2005 ) Acid and neutral sphingomyelinase, ceramide synthase, and acid ceramidase activities in cutaneous aging . Exp Dermatol 14 , 609 – 618 . 

  37. Jones , R.N. , Nilius , A.M. , Akinlade , B.K. , Deshpande , L.M. and Notario , G.F. ( 2007 ) Molecular characterization of Staphylococcus aureus isolates from a 2005 clinical trial of uncomplicated skin and skin structure infections . Antimicrob Agents Chemother 51 , 3381 – 3384 . 

  38. Kim , H.G. , Kim , N.R. , Gim , M.G. , Lee , J.M. , Lee , S.Y. , Ko , M.Y. , Kim , J.Y. , Han , S.H. et?al . ( 2008 ) Lipoteichoic acid isolated from Lactobacillus plantarum inhibits lipopolysaccharide‐induced TNF‐alpha production in THP‐1 cells and endotoxin shock in mice . J Immunol 180 , 2553 – 2561 . 

  39. Kogan , G. , Soltes , L. , Stern , R. and Gemeiner , P. ( 2007 ) Hyaluronic acid: a natural biopolymer with a broad range of biomedical and industrial applications . Biotechnol Lett 29 , 17 – 25 . 

  40. Kreder , D. , Krut , O. , Adam‐Klages , S. , Wiegmann , K. , Scherer , G. , Plitz , T. , Jensen , J.M. , Proksch , E. et?al . ( 1999 ) Impaired neutral sphingomyelinase activation and cutaneous barrier repair in FAN‐deficient mice . EMBO J 18 , 2472 – 2479 . 

  41. Kumar , M. , Kumar , A. , Nagpal , R. , Mohania , D. , Behare , P. , Verma , V. , Kumar , P. , Poddar , D. et?al . ( 2010 ) Cancer‐preventing attributes of probiotics: an update . Int J Food Sci Nutr 61 , 473 – 496 . 

  42. Lanciotti , R. , Patrignani , F. , Bagnolini , F. , Guerzoni , M.E. and Gardini , F. ( 2003 ) Evaluation of diacetyl antimicrobial activity against Escherichia coli , Listeria monocytogenes and Staphylococcus aureus . Food Microbiol 20 , 537 – 543 . 

  43. Lebeer , S. , Claes , I.J. and Vanderleyden , J. ( 2012 ) Anti‐inflammatory potential of probiotics: lipoteichoic acid makes a difference . Trends Microbiol 20 , 5 – 10 . 

  44. Lew , L.‐C. and Liong , M.‐T. ( 2012 ) Divalent ions of Mn and Mg improved sphingomyelinase activity of Lactobacillus rhamnosus FTDC 8313 . Biosci Biotechnol Biochem , in press. 

  45. Lew , L.‐C. , Gan , C.‐Y. and Liong , M.‐T. ( 2012 ) Dermal bioactives from lactobacilli and bifidobacteria . Ann Microbiol , in press, doi: 10.1007/s13213‐012‐0561‐1. 

  46. Liu , L. , Du , G. , Chen , J. , Zhu , Y. , Wang , M. and Sun , J. ( 2009 ) Microbial production of low molecular weight hyaluronic acid by adding hydrogen peroxide and ascorbate in batch culture of Streptococcus zooepidemicus . Bioresour Technol 100 , 362 – 367 . 

  47. Matsubara , M. , Harada , D. , Manabe , H. and Hasegawa , K. ( 2004 ) Staphylococcus aureus peptidoglycan stimulates granulocyte macrophage colony‐stimulating factor production from human epidermal keratinocytes via mitogen‐activated protein kinases . FEBS Lett 566 , 195 – 200 . 

  48. Menendez , A. and Brett Finlay , B. ( 2007 ) Defensins in the immunology of bacterial infections . Curr Opin Immunol 19 , 385 – 391 . 

  49. Menzies , B.E. and Kenoyer , A. ( 2005 ) Staphylococcus aureus infection of epidermal keratinocytes promotes expression of innate antimicrobial peptides . Infect Immun 73 , 5241 – 5244 . 

  50. Michail , S. ( 2009 ) The role of probiotics in allergic diseases . Allergy Asthma Clin Immunol 5 , 5 . 

  51. Middleton , J.D. ( 1974 ) Development of a skin cream designed to reduce dry and flaky skin . J Soc Cosmet Chem 25 , 519 – 534 . 

  52. Mizutani , Y. , Mitsutake , S. , Tsuji , K. , Kihara , A. and Igarashi , Y. ( 2009 ) Ceramide biosynthesis in keratinocyte and its role in skin function . Biochimie 91 , 784 – 790 . 

  53. Motta , S. , Monti , M. , Sesana , S. , Mellesi , L. , Ghidoni , R. and Caputo , R. ( 1994 ) Abnormality of water barrier function in psoriasis. Role of ceramide fractions . Arch Dermatol 130 , 452 – 456 . 

  54. Murata , Y. , Ogata , J. , Higaki , Y. , Kawashima , M. , Yada , Y. , Higuchi , K. , Tsuchiya , T. , Kawainami , S. et?al . ( 1996 ) Abnormal expression of sphingomyelin acylase in atopic dermatitis: an etiologic factor for ceramide deficiency? J Invest Dermatol 106 , 1242 – 1249 . 

  55. Nagoba , B. , Wadher , B. , Kulkarni , P. and Kolhe , S. ( 2008 ) Acetic acid treatment of pseudomonal wound infections . Eur J Gen Med 5 , 104 – 106 . 

  56. Nakagawa , N. , Sakai , S. , Matsumoto , M. , Yamada , K. , Nagano , M. , Yuki , T. , Sumida , Y. and Uchiwa , H. ( 2004 ) Relationship between NMF (lactate and potassium) content and the physical properties of the stratum corneum in healthy subjects . J Invest Dermatol 122 , 755 – 763 . 

  57. Nell , M.J. , Tjabringa , G.S. , Vonk , M.J. , Hiemstra , P.S. and Grote , J.J. ( 2004 ) Bacterial products increase expression of the human cathelicidin hCAP‐18/LL‐37 in cultured human sinus epithelial cells . FEMS Immunol Med Microbiol 42 , 225 – 231 . 

  58. Neuman , M.G. , Nanau , R.M. , Oruna , L. and Coto , G. ( 2011 ) In vitro anti‐inflammatory effects of hyaluronic acid in ethanol‐induced damage in skin cells . J Pharm Pharm Sci 14 , 425 – 437 . 

  59. Niebuhr , M. , Baumert , K. and Werfel , T. ( 2010 ) TLR‐2‐mediated cytokine and chemokine secretion in human keratinocytes . Exp Dermatol 19 , 873 – 877 . 

  60. Niyonsaba , F. and Ogawa , H. ( 2005 ) Protective roles of the skin against infection: implication of naturally occurring human antimicrobial agents beta‐defensins, cathelicidin LL‐37 and lysozyme . J Dermatol Sci 40 , 157 – 168 . 

  61. Niyonsaba , F. , Ushio , H. , Nakano , N. , Ng , W. , Sayama , K. , Hashimoto , K. , Nagaoka , I. , Okumura , K. et?al . ( 2007 ) Antimicrobial peptides human beta‐defensins stimulate epidermal keratinocyte migration, proliferation and production of proinflammatory cytokines and chemokines . J Invest Dermatol 127 , 594 – 604 . 

  62. Ooi , L.G. and Liong , M.T. ( 2010 ) Cholesterol‐lowering effects of probiotics and prebiotics: a review of in vivo and in vitro findings . Int J Mol Sci 11 , 2499 – 2522 . 

  63. Paradis‐Bleau , C. , Cloutier , I. , Lemieux , L. , Sanschagrin , F. , Laroche , J. , Auger , M. , Garnier , A. and Levesque , R.C. ( 2007 ) Peptidoglycan lytic activity of the Pseudomonas aeruginosa phage phiKZ gp144 lytic transglycosylase . FEMS Microbiol Lett 266 , 201 – 209 . 

  64. Parker , R.B. ( 1974 ) Probiotics: the other half of the antibiotic story . Anim Nutr Health 29 , 4 – 8 . 

  65. Pasricha , A. , Sharma , K. and Bhalla , P. ( 1979 ) Evaluation of lactic acid as an antibacterial agent . Indian J Dermatol Venereol Leprol 45 , 149 – 161 . 

  66. Pavicic , T. , Gauglitz , G.G. , Lersch , P. , Schwach‐Abdellaoui , K. , Malle , B. , Korting , H.C. and Farwick , M. ( 2011 ) Efficacy of cream‐based novel formulations of hyaluronic acid of different molecular weights in anti‐wrinkle treatment . J Drugs Dermatol 10 , 990 – 1000 . 

  67. Pivarcsi , A. , Nagy , I. and Kemeny , L. ( 2005 ) Innate immunity in the skin: how keratinocytes fight against pathogens . Curr Immunol Rev 1 , 29 – 42 . 

  68. Rawlings , A.V. , Davies , A. , Carlomusto , M. , Pillai , S. , Zhang , K. , Kosturko , R. , Verdejo , P. , Feinberg , C. et?al . ( 1996 ) Effect of lactic acid isomers on keratinocyte ceramide synthesis, stratum corneum lipid levels and stratum corneum barrier function . Arch Dermatol Res 288 , 383 – 390 . 

  69. Rendl , M. , Mayer , C. , Weninger , W. and Tschachler , E. ( 2001 ) Topically applied lactic acid increases spontaneous secretion of vascular endothelial growth factor by human reconstructed epidermis . Br J Dermatol 145 , 3 – 9 . 

  70. Rijkers , G.T. , Bengmark , S. , Enck , P. , Haller , D. , Herz , U. , Kalliomaki , M. , Kudo , S. , Lenoir‐Wijnkoop , I. et?al . ( 2010 ) Guidance for substantiating the evidence for beneficial effects of probiotics: current status and recommendations for future research . J Nutr 140 , 671S – 676S . 

  71. Ruemmele , F. , Bier , D. , Marteau , P. , Rechkemmer , G. , Bourdet‐Sicard , R. , Walker , W. and Goulet , O. ( 2009 ) Clinical evidence for immunomodulatory effects of probiotic bacteria . J Pediatr Gastroenterol Nutr 48 , 126 – 141 . 110.1097/MPG.1090b1013e31817d31880ca. 

  72. Ruiz‐Gonzalez , V. , Cancino‐Diaz , J.C. , Rodriguez‐Martinez , S. and Cancino‐Diaz , M.E. ( 2009 ) Keratinocytes treated with peptidoglycan from Staphylococcus aureus produce vascular endothelial growth factor, and its expression is amplified by the subsequent production of interleukin‐13 . Int J Dermatol 48 , 846 – 854 . 

  73. Russell , J.B. and Diez‐Gonzalez , F. ( 1998 ) The effects of fermentation acids on bacterial growth . Adv Microb Physiol 39 , 205 – 234 . 

  74. Ryssel , H. , Kloeters , O. , Germann , G. , Schafer , T. , Wiedemann , G. and Oehlbauer , M. ( 2009 ) The antimicrobial effect of acetic acid–an alternative to common local antiseptics? Burns 35 , 695 – 700 . 

  75. Saha , S. , Tomaro‐Duchesneau , C. , Tabrizian , M. and Prakash , S. ( 2012 ) Probiotics as oral health biotherapeutics . Expert Opin Biol Ther 12 , 1207 – 1220 . 

  76. Schauber , J. and Gallo , R.L. ( 2008 ) Antimicrobial peptides and the skin immune defense system . J Allergy Clin Immunol 122 , 261 – 266 . 

  77. Schmuth , M. , Man , M.Q. , Weber , F. , Gao , W. , Feingold , K.R. , Fritsch , P. , Elias , P.M. and Holleran , W.M. ( 2000 ) Permeability barrier disorder in Niemann‐Pick disease: sphingomyelin‐ceramide processing required for normal barrier homeostasis . J Invest Dermatol 115 , 459 – 466 . 

  78. Shida , K. , Kiyoshima‐Shibata , J. , Kaji , R. , Nagaoka , M. and Nanno , M. ( 2009 ) Peptidoglycan from lactobacilli inhibits interleukin‐12 production by macrophages induced by Lactobacillus casei through Toll‐like receptor 2‐dependent and independent mechanisms . Immunology 128 , e858 – e869 . 

  79. Shiedlin , A. , Bigelow , R. , Christopher , W. , Arbabi , S. , Yang , L. , Maier , R.V. , Wainwright , N. , Childs , A. et?al . ( 2004 ) Evaluation of hyaluronan from different sources: Streptococcus zooepidemicus , rooster comb, bovine vitreous, and human umbilical cord . Biomacromolecules 5 , 2122 – 2127 . 

  80. Sloss , J.M. , Cumberland , N. and Milner , S.M. ( 1993 ) Acetic acid used for the elimination of Pseudomonas aeruginosa from burn and soft tissue wounds . J R Army Med Corps 139 , 49 – 51 . 

  81. Smith , W.P. ( 1996 ) Epidermal and dermal effects of topical lactic acid . J Am Acad Dermatol 35 , 388 – 391 . 

  82. Sorensen , O.E. , Thapa , D.R. , Rosenthal , A. , Liu , L. , Roberts , A.A. and Ganz , T. ( 2005 ) Differential regulation of beta‐defensin expression in human skin by microbial stimuli . J Immunol 174 , 4870 – 4879 . 

  83. Sumikawa , Y. , Asada , H. , Hoshino , K. , Azukizawa , H. , Katayama , I. , Akira , S. and Itami , S. ( 2006 ) Induction of beta‐defensin 3 in keratinocytes stimulated by bacterial lipopeptides through toll‐like receptor 2 . Microbes Infect 8 , 1513 – 1521 . 

  84. Sun , J. , Shi , Y.H. , Le , G.W. and Ma , X.Y. ( 2005 ) Distinct immune response induced by peptidoglycan derived from Lactobacillus sp . World J Gastroenterol 11 , 6330 – 6337 . 

  85. Taylor , K.R. , Trowbridge , J.M. , Rudisill , J.A. , Termeer , C.C. , Simon , J.C. and Gallo , R.L. ( 2004 ) Hyaluronan fragments stimulate endothelial recognition of injury through TLR4 . J Biol Chem 279 , 17079 – 17084 . 

  86. Titball , R.W. ( 1993 ) Bacterial phospholipases C . Microbiol Rev 57 , 347 – 366 . 

  87. Trabucchi , E. , Pallotta , S. , Morini , M. , Corsi , F. , Franceschini , R. , Casiraghi , A. , Pravettoni , A. , Foschi , D. et?al . ( 2002 ) Low molecular weight hyaluronic acid prevents oxygen free radical damage to granulation tissue during wound healing . Int J Tissue React 24 , 65 – 71 . 

  88. Van Scott , E.J. , Ditre , C.M. and Yu , R.J. ( 1996 ) Alpha‐hydroxyacids in the treatment of signs of photoaging . Clin Dermatol 14 , 217 – 226 . 

  89. Viljanen , M. , Savilahti , E. , Haahtela , T. , Juntunen‐Backman , K. , Korpela , R. , Poussa , T. , Tuure , T. and Kuitunen , M. ( 2005 ) Probiotics in the treatment of atopic eczema/dermatitis syndrome in infants: a double‐blind placebo‐controlled trial . Allergy 60 , 494 – 500 . 

  90. de Vrese , M. ( 2009 ) Health benefits of probiotics and prebiotics in women . Menopause Int 15 , 35 – 40 . 

  91. Wang , X. ( 1999 ) A theory for the mechanism of action of the alpha‐hydroxy acids applied to the skin . Med Hypotheses 53 , 380 – 382 . 

  92. Wang , Z. , MacLeod , D.T. and Di Nardo , A. ( 2012 ) Commensal bacteria lipoteichoic acid increases skin mast cell antimicrobial activity against vaccinia viruses . J Immunol 189 , 1551 – 1558 . 

  93. Wee , Y.J. , Kim , J.N. and Ryu , H.W. ( 2006 ) Biotechnological production of lactic acid and its recent applications . Food Technol Biotechnol 44 , 163 – 172 . 

  94. Weindl , G. , Schaller , M. , Schafer‐Korting , M. and Korting , H.C. ( 2004 ) Hyaluronic acid in the treatment and prevention of skin diseases: molecular biological, pharmaceutical and clinical aspects . Skin Pharmacol Physiol 17 , 207 – 213 . 

  95. Widner , B. , Behr , R. , Von Dollen , S. , Tang , M. , Heu , T. , Sloma , A. , Sternberg , D. , Deangelis , P.L. et?al . ( 2005 ) Hyaluronic acid production in Bacillus subtilis . Appl Environ Microbiol 71 , 3747 – 3752 . 

  96. Yamamoto , Y. , Uede , K. , Yonei , N. , Kishioka , A. , Ohtani , T. and Furukawa , F. ( 2006 ) Effects of alpha‐hydroxy acids on the human skin of Japanese subjects: the rationale for chemical peeling . J Dermatol 33 , 16 – 22 . 

  97. Yang , S. , Tamai , R. , Akashi , S. , Takeuchi , O. , Akira , S. , Sugawara , S. and Takada , H. ( 2001 ) Synergistic effect of muramyldipeptide with lipopolysaccharide or lipoteichoic acid to induce inflammatory cytokines in human monocytic cells in culture . Infect Immun 69 , 2045 – 2053 . 

  98. Yeo , S.K. and Liong , M.T. ( 2010 ) Effect of prebiotics on viability and growth characteristics of probiotics in soymilk . J Sci Food Agric 90 , 267 – 275 . 

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