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Inhibition of CYP1 by berberine, palmatine, and jatrorrhizine: Selectivity, kinetic characterization, and molecular modeling

Toxicology and applied pharmacology, v.272 no.3, 2013년, pp.671 - 680  

Lo, S.N. ,  Chang, Y.P. ,  Tsai, K.C. ,  Chang, C.Y. ,  Wu, T.S. ,  Ueng, Y.F.

Abstract AI-Helper 아이콘AI-Helper

Cytochrome P450 (P450, CYP) 1 family plays a primary role in the detoxification and bioactivation of polycyclic aromatic hydrocarbons. Human CYP1A1, CYP1A2, and CYP1B1 exhibit differential substrate specificity and tissue distribution. Berberine, palmatine, and jatrorrhizine are protoberberine alkal...

주제어

참고문헌 (47)

  1. Mol. Pharmacol. Aklillu 61 586 2002 10.1124/mol.61.3.586 Functional analysis of six different polymorphic CYP1B1 enzyme variants found in an Ethiopian population 

  2. Cancer Res. Aklillu 65 5105 2005 10.1158/0008-5472.CAN-05-0113 Characterization of common CYP1B1 variants with different capacity for benzo(a)pyrene-7,8-dihydrodiol epoxide formation from benzo(a)pyrene 

  3. Cancer Res. Bailey 58 5038 1998 Association of cytochrome P450 1B1 (CYP1B1) polymorphism with steroid receptor status in breast cancer 

  4. Drug Metab. Dispos. Chatterjee 31 1391 2003 10.1124/dmd.31.11.1391 Human cytochrome P450 inhibition and metabolic-intermediate complex formation by goldenseal extract and its methylenedioxyphenyl components 

  5. Drug Metab. Dispos. Choudhary 32 840 2004 10.1124/dmd.32.8.840 Metabolism of retinoids and arachidonic acid by human and mouse cytochrome P450 1B1 

  6. Biotechnol. Bioeng. Chu 108 2932 2011 10.1002/bit.23256 Development of a whole-cell screening system for evaluation of the human CYP1A2-mediated metabolism 

  7. Cancer Res. Chun 61 8164 2001 A new selective and potent inhibitor of human cytochrome P450 1B1 and its application to antimutagenesis 

  8. Fitoterapia Douglas 81 925 2010 10.1016/j.fitote.2010.06.006 Seasonal variation of biomass and bioactive alkaloid content of goldenseal, Hydrastis Canadensis 

  9. Cancer Lett. Gajjar 324 13 2012 10.1016/j.canlet.2012.04.021 CYP1B1 and hormone-induced cancer 

  10. J. Pharmacol. Exp. Ther. Greenlee 205 596 1978 An improved assay of 7-ethoxycoumarin deethylase activity: induction of hepatic enzyme activity in C57BL/6J and DBA/2J mice by phenobarbital, 3-methylcholanthrene and 2,3,7,8-tetrachlorodibenzo-p-dioxin 

  11. Phytochemistry Grycova 68 150 2007 10.1016/j.phytochem.2006.10.004 Quaternary protoberberine alkaloids 

  12. Eur. J. Clin. Pharmacol. Guo 68 213 2012 10.1007/s00228-011-1108-2 Repeated administration of berberine inhibits cytochromes P450 in humans 

  13. Phytother. Res. Han 25 1660 2011 10.1002/ptr.3475 In vitro inhibition of Huanglian[Rhizoma coptidis (L.)] and its six active alkaloids on six cytochrome P450 isoforms in human liver microsomes 

  14. Cancer Res. Hanna 60 3440 2000 Cytochrome P450 1B1 (CYP1B1) pharmacogenetics: association of polymorphisms with functional differences in estrogen hydroxylation activity 

  15. Mol. Cell. Endocrinol. Hevir 331 158 2011 10.1016/j.mce.2010.09.011 Disturbed expression of phase I and phase II estrogen-metabolizing enzymes in endometrial cancer: lower levels of CYP1B1 and increased expression of S-COMT 

  16. Hypertension Jennings 56 667 2010 10.1161/HYPERTENSIONAHA.110.154518 Cytochrome P450 1B1 contributes to angiotensin II-induced hypertension and associated pathophysiology 

  17. Hypertension Jennings 59 348 2012 10.1161/HYPERTENSIONAHA.111.183301 Cytochrome P450 1B1 contributes to renal dysfunction and damage caused by angiotensin II in mice 

  18. Am. J. Physiol. Renal Physiol. Jennings 302 F408 2012 10.1152/ajprenal.00542.2011 Involvement of cytochrome P-450 1B1 in renal dysfunction, injury, and inflammation associated with angiotensin II-induced hypertension in rats 

  19. Vascul. Pharmacol. Kang 39 281 2003 10.1016/S1537-1891(03)00005-3 Effects of berberine on angiotensin-converting enzyme and NO/cGMP system in vessels 

  20. Breast Cancer Res. Treat. Kim 126 779 2011 10.1007/s10549-010-1301-5 Tetra-methoxystilbene modulates ductal growth of the developing murine mammary gland 

  21. Phytochemistry Kulkarni 24 317 2010 Berberine: a plant alkaloid with therapeutic potential for central nervous system disorders 

  22. Biochem. Mol. Biol. Int. Lee 34 483 1994 Modulation of cytochrome P450 activities by 7,8-benzoflavone and its metabolites 

  23. Endocrinology Lee 144 3382 2003 10.1210/en.2003-0192 Characterization of the oxidative metabolites of 17β-estradiol and estrone formed by 15 selectively expressed human cytochrome P450 isoforms 

  24. Toxicology Lewis 139 53 1999 10.1016/S0300-483X(99)00098-0 Molecular modelling of CYP1 family enzymes CYP1A1, CYP1A2, CYP1A6 and CYP1B1 based on sequence homology with CYP102 

  25. J. Transl. Med. Li 9 62 2011 10.1186/1479-5876-9-62 Bioactivities of berberine metabolites after transformation through P450 isoenzymes 

  26. Chem. Res. Toxicol. Liu 25 1047 2012 10.1021/tx300023p 7-Ethynylcoumarins: selective inhibitors of human cytochrome P450s 1A1 and 1A2 

  27. Prostaglandins Other Lipid Mediat. Malik 98 69 2012 10.1016/j.prostaglandins.2011.12.003 Contribution of cytochrome P450 1B1 to hypertension and associated pathophysiology: a novel target for antihypertensive agents 

  28. Bioorg. Med. Chem. Mikstacka 20 5117 2012 10.1016/j.bmc.2012.07.012 Design, synthesis and evaluation of the inhibitory selectivity of novel trans-resveratrol analogues on human recombinant CYP1A1, CYP1A2 and CYP1B1 

  29. J. Biol. Chem. Nebert 243 6242 1968 10.1016/S0021-9258(18)94484-4 Substrate-inducible microsomal aryl hydroxylase in mammalian cell culture. I. Assembly and properties of induced enzyme 

  30. J. Biol. Chem. Omura 239 2370 1964 10.1016/S0021-9258(20)82244-3 The carbon monoxide-binding pigment of liver microsomes. l. Evidence for its hemeprotein nature 

  31. Am. J. Epidemiol. Paracchini 165 115 2007 10.1093/aje/kwj365 Meta- and pooled analyses of the cytochrome P-450 1B1 Val432Leu polymorphism and breast cancer: a HuGE-GSEC review 

  32. Nat. Biotechnol. Parikh 15 784 1997 10.1038/nbt0897-784 Drug metabolism by Escherichia coli expressing human cytochrome P450 

  33. J. Biol. Chem. Phillips 237 2652 1962 10.1016/S0021-9258(19)73803-4 Hepatic triphosphopyridine nucleotide-cytochrome c reductase: isolation, characterization, and kinetic studies 

  34. Anal. Biochem. Pohl 107 150 1980 10.1016/0003-2697(80)90505-9 A rapid method for assaying the metabolism of 7-ethoxyresorufin by microsomal subcellular fractions 

  35. Biochemistry Sampedro 46 5616 2007 10.1021/bi700016v Fluorescence quenching by nucleotides of the plasma membrane H+-ATPase from Kluyveromyces lactis 

  36. Cancer Res. Shimada 56 2979 1996 Activation of chemically diverse procarcinogens by human cytochrome P-450 1B1 

  37. Arch. Biochem. Biophys. Shimada 357 111 1998 10.1006/abbi.1998.0808 Recombinant human cytochrome P450 1B1 expression in Escherichia coli 

  38. Chem. Res. Toxicol. Shimada 11 1048 1998 10.1021/tx980090+ Selectivity of polycyclic inhibitors for human cytochrome P450s 1A1, 1A2, and 1B1 

  39. J. Nat. Prod. Su 70 1930 2007 10.1021/np0704248 Cytochrome P450 3A4 inhibitors and other constituents of Fibraurea tinctoria 

  40. J. Biol. Chem. Sutter 269 13092 1994 10.1016/S0021-9258(17)36803-5 Complete cDNA sequence of a human dioxin-inducible mRNA identifies a new gene subfamily of cytochrome P450 that maps to chromosome 2 

  41. J. Ethnopharmacol. Tang 126 5 2009 10.1016/j.jep.2009.08.009 Berberine and Coptidis Rhizoma as novel antineoplastic agents: a review of traditional use and biomedical investigations 

  42. Biochem. Pharmacol. Vrzal 70 925 2005 10.1016/j.bcp.2005.06.016 Activation of the aryl hydrocarbon receptor by berberine in HepG2 and H4IIE cells: biphasic effect on CYP1A1 

  43. J. Biol. Chem. Wang 286 5736 2011 10.1074/jbc.M110.204420 Structural characterization of the complex between α-naphthoflavone and human cytochrome CYP1B1? 

  44. Breast Cancer Res. Treat. Yao 122 237 2010 10.1007/s10549-009-0689-2 No association between CYP1B1 Val432Leu polymorphism and breast cancer risk: a meta-analysis involving 40,303 subjects 

  45. Biomed. Chromatogr. Zan 25 816 2011 10.1002/bmc.1521 Simultaneous quantification of multiple active components from Xiexin decoction in rat plasma by LC-ESI-MS/MS: application in pharmacokinetics 

  46. Biomed. Chromatogr. Zeng 13 442 1999 10.1002/(SICI)1099-0801(199911)13:7<442::AID-BMC908>3.0.CO;2-A Relationship between the clinical effects of berberine on severe congestive heart failure and its concentration in plasma studied by HPLC 

  47. Phytother. Res. Zhao 26 277 2012 10.1002/ptr.3554 The in vitro inhibition of human CYP1A2, CYP2D6 and CYP3A4 by tetrahydropalmatine, neferine and berberine 

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