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Injectable microsphere/hydrogel hybrid system containing heat shock protein as therapy in a murine myocardial infarction model

Journal of drug targeting, v.21 no.9, 2013년, pp.822 - 829  

Lee, Jangwook (Department of Bioengineering, Hanyang University , Seoul , Republic of Korea ,) ,  Cha, Min-Ji (Cardiovascular Research Institute, Yonsei University College of Medicine , Seoul 120-752 , Republic of Korea ,) ,  Lim, Kwang Suk (Department of Bioengineering, Hanyang University , Seoul , Republic of Korea ,) ,  Kim, Jang-Kyung (Department of Bioengineering, Hanyang University , Seoul , Republic of Korea ,) ,  Lee, Sang-Kyung (Department of Bioengineering, Hanyang University , Seoul , Republic of Korea ,) ,  Kim, Yong-Hee (Department of Bioengineering, Hanyang University , Seoul , Republic of Korea Hwang, Ki-Chul ,  Lee, Kuen Yong

Abstract AI-Helper 아이콘AI-Helper

Heat shock proteins, acting as molecular chaperones, protect heart muscle from ischemic injury and offer a potential approach to therapy. Here we describe preparation of an injectable form of heat shock protein 27, fused with a protein transduction domain (TAT-HSP27) and contained in a hybrid system...

주제어

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