[논문]Chronic kidney disease and diabetes in the National Health Service: a cross‐sectional survey of the UK National Diabetes Audit

doi:10.1111/dme.12312

[해외논문] Chronic kidney disease and diabetes in the National Health Service: a cross‐sectional survey of the UK National Diabetes Audit 원문보기

Diabetic medicine : a journal of the British Diabetic Association, v.31 no.4, 2014년, pp.448 - 454

Hill, C. J. (Centre for Public Health, Queen's University Belfast, Belfast, UK) , Cardwell, C. R. (Centre for Public Health, Queen's University Belfast, Belfast, UK) , Patterson, C. C. (Centre for Public Health, Queen's University Belfast, Belfast, UK) , Maxwell, A. P. (Centre for Public Health, Queen's University Belfast, Belfast, UK) , Magee, G. M. (Department of General Medicine, Daisy Hill Hospital, Newry, UK) , Young, R. J. (National Diabetes Audit and National Diabetes Information Service, Salford Royal Foundation NHS Trust, Salford, UK) , Matthews, B. (NHS Kidney Care, Newcastle upon Tyne, Salford, UK) , O'Donoghue, D. J. (Salford Royal Foundation NHS Trust, Salford, UK) , Fogarty, D. G. (Centre for Public Health, Queen's University Belfast, Belfast, UK)

Abstract ▼ AI-Helper

AbstractAimsWe investigated the prevalence of chronic kidney disease and attainment of therapeutic targets for HbA1c and blood pressure in a large UK‐based diabetes population.MethodsThe UK National Diabetes Audit provided data from 1 January 2007 to 31 March 2008. Inclusion criteria were a documented urinary albumin:creatinine ratio and serum creatinine. Patients were stratified according to chronic kidney disease stage and albuminuria status. Chronic kidney disease was defined as an estimated glomerular filtration rate <？60？ml？min−1？1.73？m−2, albuminuria or both. The proportions of patients achieving nationally defined glycaemic and systolic blood pressure targets were determined.ResultsThe cohort comprised 1？423？669 patients, of whom 868？616 (61%) met inclusion criteria. Of the patients analysed, 92.2% had Type？2 diabetes. A higher proportion of people with Type？2 diabetes (42.3%) had renal dysfunction compared with those with Type？1 diabetes (32.4%). Achievement of systolic blood pressure and HbA1c targets was poor. Among people with Type？1 diabetes, 67.8% failed to achieve an HbA1c <？58？mmol/mol (7.5%). Of all people with diabetes, 37.8% failed to achieve a systolic blood pressure <？140？mmHg. Blood pressure control was poor in advanced chronic kidney disease. For example, mean (standard deviation) systolic blood pressure rose from 128.6 (15.4) mmHg among people with Type？1 diabetes and normal renal function to 141.0 (23.6) mmHg in those with chronic kidney disease stage？5 and macroalbuminuria.ConclusionsThe high prevalence of chronic kidney disease and poor attainment of treatment targets highlights a large subset of the diabetes population at increased risk of cardiovascular mortality or progressive kidney disease.

Abstract

What's new?This is the largest study of its kind using data extracted directly from routine healthcare records of people in the UK with diabetes.We have documented a large group of people with Type？1 and Type？2 diabetes who have significant reductions in estimated glomerular filtration rate in the absence of albuminuria.Despite nationally approved clinical guidance and an incentivized remuneration scheme in primary care, we also found that many patients were failing to achieve minimum targets for blood pressure and blood glucose control.

참고문헌 (26)

Wild S , Roglic G , Green A , Sicree R , King H . Global prevalence of diabetes: estimates for the year 2000 and projections for 2030 . Diabetes Care 2004 ; 27 : 1047 – 1053 .

상세보기
Patterson CC , Dahquist GG , Gyurus E , Green A . Soltesz G on behalf of the Eurodiab Study Group. Incidence trends for childhood type？1 diabetes in Europe during 1989–2003 and predicted new cases 2005–2020: a multicentre prospective registration study . Lancet 2009 ; 373 : 2027 – 2033 .
Gilg J , Castledine C , Fogarty D . UK renal registry 14th annual report: chapter？1 UK RRT incidence in 2010: national and centre‐specific analyses . Nephron Clin Pract 2012 ; 120 : C1 – C27 .
Foley RN , Murray AM , Li SL , Herzog CA , McBean AM , Eggers PW et al . Chronic kidney disease and the risk for cardiovascular disease, renal replacement, and death in the United States medicare population, 1998 to 1999 . J Am Soc Nephrol 2005 ; 16 : 489 – 495 .

상세보기
Gerstein HC , Mann JFE , Yi QL , Zinman B , Dinneen SF , Hoogwerf B , et al . Albuminuria and risk of cardiovascular events, death, and heart failure in diabetic and nondiabetic individuals . J Am Med Assoc 2001 ; 286 : 421 – 426 .
American Diabetes Association . Economic costs of diabetes in the US in 2012 . Diabetes Care 2013 ; 36 : 1033 – 1046 .

상세보기
Holman RR , Paul SK , Bethel MA , Matthews DR , Neil HAW . 10‐year follow‐up of intensive glucose control in type？2 diabetes . N Engl J Med 2008 ; 359 : 1577 – 1589 .

상세보기
de Boer IH , Sun WJ , Cleary PA , Lachin JM , Molitch ME , Steffes MW et al . Intensive diabetes therapy and glomerular filtration rate in type？1 diabetes . N Engl J Med 2011 ; 365 : 2366 – 2376 .

상세보기
Holman RR , Paul SK , Bethel MA , Neil HAW , Matthews DR . Long‐term follow‐up after tight control of blood pressure in type？2 diabetes . N Engl J Med 2008 ; 359 : 1565 – 1576 .

상세보기
National Clinical Audit Support Programme . National Diabetes Audit . United Kingdom 2013. Available at http://www.hscic.gov.uk/nda Last accessssed 1 June 2013.
Levey AS , Stevens LA , Schmid CH , Zhang YP , Castro AF , Feldman HI , et al . A new equation to estimate glomerular filtration rate . Ann Intern Med 2009 ; 150 : 604 – 612 .

상세보기
Matsushita K , Mahmoodi BK , Woodward M , Emberson JR , Jafar TH , Jee SH et al . Comparison of risk prediction using the CKD‐EPI equation and the MDRD Study equation for estimated glomerular filtration rate . J Am Med Assoc 2012 ; 307 : 1941 – 1951 .
Levey AS , Coresh J , Greene T , Marsh J , Stevens LA , Kusek JW et al . Expressing the modification of diet in renal disease study equation for estimating glomerular filtration rate with standardized serum creatinine values . Clin Chem 2007 ; 53 : 766 – 772 .

상세보기
NICE . Management of Type？2 Diabetes. Management of Blood Glucose . Clinical guideline？G. London : National Institute for Health and Clinical Excellence , 2002 .
NICE . Management of Type？2 Diabetes. Management of Blood Pressure and Blood Lipids . Clinical guideline？H. London : National Institute for Health and Clinical Excellence , 2002 .
NICE . Type？1 Diabetes: Diagnosis and Management of Type？1 Diabetes in Children, Young People and Adults (CG15). London : National Institute for Health and Clinical Excellence , 2004 .
de Boer IH , Rue TC , Hall YN , Heagerty PJ , Weiss NS , Himmelfarb J . Temporal trends in the prevalence of diabetic kidney disease in the United States . J Am Med Assoc 2011 ; 305 : 2532 – 2539 .
Kim ESH , Samuels TA , Yeh HC , Abuid M , Marinopoulos SS , McCauley JM et al . End‐digit preference and the quality of blood pressure monitoring in diabetic adults . Diabetes Care 2007 ; 30 : 1959 – 1963 .

상세보기
Cheung BMY , Ong KL , Cherny SS , Sham PC , Tso AWK , Lam KSL . Diabetes prevalence and therapeutic target achievement in the United States, 1999 to 2006 . Am J Med 2009 ; 122 : 443 – 453 .

상세보기
Magee GM , Hunter SJ , Cardwell CR , Savage G , Kee F , Murphy MC et al . Identifying additional patients with diabetic nephropathy using the UK primary care initiative . Diabet Med 2010 ; 27 : 1372 – 1378 .

상세보기
Campbell SM , Reeves D , Kontopantelis E , Sibbald B , Roland M . Effects of pay for performance on the quality of primary care in England . N Engl J Med 2009 ; 361 : 368 – 378 .

상세보기
Alshamsan R , Lee JT , Majeed A , Netuveli G , Millett C . Effect of a UK pay‐for‐performance program on ethnic disparities in diabetes outcomes: interrupted time series analysis . Ann Fam Med 2012 ; 10 : 228 – 234 .
O'Connor PJ , Bodkin NL , Fradkin J , Glasgow RE , Greenfield S , Gregg E et al . Diabetes performance measures: current status and future directions . Diabetes Care 2011 ; 34 : 1651 – 1659 .

상세보기
Weinstock RS , Teresi JA , Goland R , Izquierdo R , Palmas W , Eimicke JP et al . Glycemic control and health disparities in older ethnically diverse underserved adults with diabetes five‐year results from the Informatics for Diabetes Education and Telemedicine (IDEATel) study . Diabetes Care 2011 ; 34 : 274 – 279 .
Centers for Disease Control and Prevention . National Diabetes Fact Sheet: National Estimates and General Information on Diabetes and Prediabetes in the United States, 2011 . Atlanta : Department of Health and Human Services , 2011 .
Coresh J , Astor BC , Greene T , Eknoyan G , Levey AS . Prevalence of chronic kidney disease and decreased kidney function in the adult US population: Third National Health and Nutrition Examination Survey . Am J Kidney Dis 2003 ; 41 : 1 – 12 .

상세보기

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[해외논문] Chronic kidney disease and diabetes in the National Health Service: a cross‐sectional survey of the UK National Diabetes Audit 원문보기

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