$\require{mediawiki-texvc}$

연합인증

연합인증 가입 기관의 연구자들은 소속기관의 인증정보(ID와 암호)를 이용해 다른 대학, 연구기관, 서비스 공급자의 다양한 온라인 자원과 연구 데이터를 이용할 수 있습니다.

이는 여행자가 자국에서 발행 받은 여권으로 세계 각국을 자유롭게 여행할 수 있는 것과 같습니다.

연합인증으로 이용이 가능한 서비스는 NTIS, DataON, Edison, Kafe, Webinar 등이 있습니다.

한번의 인증절차만으로 연합인증 가입 서비스에 추가 로그인 없이 이용이 가능합니다.

다만, 연합인증을 위해서는 최초 1회만 인증 절차가 필요합니다. (회원이 아닐 경우 회원 가입이 필요합니다.)

연합인증 절차는 다음과 같습니다.

최초이용시에는
ScienceON에 로그인 → 연합인증 서비스 접속 → 로그인 (본인 확인 또는 회원가입) → 서비스 이용

그 이후에는
ScienceON 로그인 → 연합인증 서비스 접속 → 서비스 이용

연합인증을 활용하시면 KISTI가 제공하는 다양한 서비스를 편리하게 이용하실 수 있습니다.

[해외논문] Application of capillary electrophoresis for the early diagnosis of cancer

Analytical and bioanalytical chemistry, v.406 no.17, 2014년, pp.4013 - 4031  

Yang, Zhiyong ,  Sweedler, Jonathan V.

Abstract AI-Helper 아이콘AI-Helper

Early diagnosis is the key to the effective treatment of cancer. The detection of cancer biomarkers plays a critical role not only in cancer early diagnosis, but also in classification and staging tumor progression, or assessment prognosis and treatment response. Currently, various molecular diagnos...

참고문헌 (141)

  1. Exp Biol Med R Miturski 227 8 579 2002 10.1177/153537020222700805 Miturski R, Bogusiewicz M, Ciotta C, Bignami M, Gogacz M, Burnouf D (2002) Mismatch repair genes and microsatellite instability as molecular markers for gynecological cancer detection. Exp Biol Med 227(8):579-586 

  2. J Mol Med MW Beckmann 75 6 429 1997 10.1007/s001090050128 Beckmann MW, Niederacher D, Schnürch HG, Gusterson BA, Bender HG (1997) Multistep carcinogenesis of breast cancer and tumour heterogeneity. J Mol Med 75(6):429-439 

  3. Proteome Sci M Abramovitz 4 5 1 2006 Abramovitz M, Leyland-Jones B (2006) A systems approach to clinical oncology: focus on breast cancer. Proteome Sci 4(5):1-5 

  4. Eur Urol R Henrique 46 660 2004 10.1016/j.eururo.2004.06.014 Henrique R, Jeronimo C (2004) Molecular detection of prostate cancer: a role for GSTP1 hypermethylation. Eur Urol 46:660-669 

  5. Respiration P Astoul 83 6 481 2012 10.1159/000339259 Astoul P, Roca E, Galateau-Salle F, Scherpereel A (2012) Malignant pleural mesothelioma: from the bench to the bedside. Respiration 83(6):481-493 

  6. Clin Pharmacol Ther Biomarkers definitions working group 69 89 2001 10.1067/mcp.2001.113989 Biomarkers definitions working group (2001) Biomarkers and surrogate endpoints: preferred definitions and conceptual framework. Clin Pharmacol Ther 69:89-95 

  7. Clin Chem MP Pavlou 59 147 2013 10.1373/clinchem.2012.184614 Pavlou MP, Diamandis EP, Blasutig IM (2013) The long journey of cancer biomarkers from the bench to the clinic. Clin Chem 59:147-157 

  8. Sci Transl Med WD Hazelton 3 109 2011 10.1126/scitranslmed.3003272 Hazelton WD, Luebeck EG (2011) Biomarker-based early cancer detection: is it achievable? Sci Transl Med 3:109-114 

  9. J Natl Cancer Inst SG Baker 101 1 2009 Baker SG (2009) Improving the biomarker pipeline to develop and evaluate cancer screening tests. J Natl Cancer Inst 101:1-4 

  10. Clin Chem RD Rodland 60 290 2014 10.1373/clinchem.2013.216382 Rodland RD (2014) As if biomarker discovery isn’t hard enough: the consequences of poorly characterized reagents. Clin Chem 60:290-291 

  11. J Natl Cancer Inst EP Diamandis 102 1462 2010 10.1093/jnci/djq306 Diamandis EP (2010) Cancer biomarkers: can we turn recent failures into success? J Natl Cancer Inst 102:1462-1467 

  12. Clin Chem D Konforte 59 35 2013 10.1373/clinchem.2012.184903 Konforte D, Diamandis EP (2013) Is early detection of cancer with circulating biomarkers feasible? Clin Chem 59:35-37 

  13. Cancer Res SE Kern 72 6097 2012 10.1158/0008-5472.CAN-12-3232 Kern SE (2012) Why your new cancer biomarker may never work: recurrent patterns and remarkable diversity in biomarker failures. Cancer Res 72:6097-6101 

  14. Clin Chem HE Witkowska 58 321 2012 10.1373/clinchem.2011.175034 Witkowska HE, Hall SC, Fisher SJ (2012) Breaking the bottleneck in the protein biomarker pipeline. Clin Chem 58:321-323 

  15. Pathol Int H Iwasaki 59 8 501 2009 10.1111/j.1440-1827.2009.02401.x Iwasaki H, Nabeshima K, Nishio J, Jimi S, Aoki M, Koga K, Hamasaki M, Hayashil H, Mogil A (2009) Pathology of soft-tissue tumors: daily diagnosis, molecular cytogenetics, and experimental approach. Pathol Int 59(8):501-521 

  16. Pathol Res Pract JI López 209 3 137 2013 10.1016/j.prp.2013.01.007 López JI (2013) Renal tumors with clear cells. Pathol Res Pract 209(3):137-146 

  17. J Surg Oncol HT Lynch 90 3 114 2005 10.1002/jso.20214 Lynch HT, Grady W, Suriano G, Huntsman D (2005) Gastric cancer: new genetic developments. J Surg Oncol 90(3):114-133 

  18. Clin Chim Acta IJ Schultz 368 1/2 20 2006 10.1016/j.cca.2005.12.036 Schultz IJ, Witjes JA, Swinkels DW, Kok JB (2006) Bladder cancer diagnosis and recurrence prognosis: comparison of markers with emphasis on survivin. Clin Chim Acta 368(1/2):20-32 

  19. J Cutan Pathol M Brunelli 36 6 702 2009 10.1111/j.1600-0560.2008.01114.x Brunelli M, Manfrin E, Miller K, Eccher A, Gobbo S, Reghellin D, Chilosi M, Remo A, Martignoni G, Menestrina F, Bonetti F (2009) Her-2/neu evaluation in Sister Mary Joseph’s nodule from breast carcinoma: a case report and review of the literature. J Cutan Pathol 36(6):702-705 

  20. Breast Cancer Res K Rennstam 8 4 213 2006 10.1186/bcr1528 Rennstam K, Hedenfalk I (2006) Molecular signatures of progression from benign epithelium to metastatic breast cancer. Breast Cancer Res 8(4):213-217 

  21. Expert Rev Mol Diagn MH Oktay 12 8 811 2012 10.1586/erm.12.121 Oktay MH, Hui P (2012) Molecular pathology as the driving force for personalized oncology. Expert Rev Mol Diagn 12(8):811-813 

  22. Pancreatology R Brandta 4 587 2004 10.1159/000082241 Brandta R, Grützmannb R, Bauerc A, Jesenofskya R, Ringela J, Löhra M, Pilarskyb C, Hoheiselc JD (2004) DNA microarray analysis of pancreatic malignancies. Pancreatology 4:587-597 

  23. Dig Dis M Buchholz 21 4 309 2003 10.1159/000075353 Buchholz M, Gress TM (2003) Application of DNA array analyses in the management of gastrointestinal cancer patients. Dig Dis 21(4):309-314 

  24. Cancer Lett M Ohira 228 1/2 5 2005 10.1016/j.canlet.2005.01.054 Ohira M, Oba S, Nakamura Y, Hirata T, Ishii S, Nakagawara A (2005) A review of DNA microarray analysis of human neuroblastomas. Cancer Lett 228(1/2):5-11 

  25. JAMA BR Korf 309 14 1511 2005 10.1001/jama.2013.3239 Korf BR, Rehm HL (2005) New approaches to molecular diagnosis. JAMA 309(14):1511-1521 

  26. Expert Rev Mol Diagn V Özdemir 12 8 783 2012 10.1586/erm.12.127 Özdemir V, Cho WCS (2012) Theranostics: rethinking postgenomic diagnostics. Expert Rev Mol Diagn 12(8):783-785 

  27. Crit Rev Oncol Hematol WM Abdel-Rahman 58 3 208 2006 10.1016/j.critrevonc.2005.11.001 Abdel-Rahman WM, Mecklin JP, Peltomaki P (2006) The genetics of HNPCC: application to diagnosis and screening. Crit Rev Oncol Hematol 58(3):208-220 

  28. Mol Cancer P Anglim 7 81 2008 10.1186/1476-4598-7-81 Anglim P, Alonzo TA, Laird-Offring IA (2008) DNA methylation-based biomarkers for early detection of non-small-cell lung cancer: an update. Mol Cancer 7:81-96 

  29. Electrophoresis M Hamada 34 9/10 1415 2013 10.1002/elps.201200671 Hamada M, Shimase K, Noda K, Tsukagoshi K, Hashimoto M (2013) Development of a ligase detection reaction/CGE method using a LIF dual-channel detection system for direct identification of allelic composition of mutated DNA in a mixed population of excess wild-type DNA. Electrophoresis 34(9/10):1415-1422 

  30. J Pharm Biomed E Szymanska 53 5 1305 2010 10.1016/j.jpba.2010.07.031 Szymanska E, Markuszewski MJ, Markuszewski M, Kaliszan R (2010) Altered levels of nucleoside metabolite profiles in urogenital tract cancer measured by capillary electrophoresis. J Pharm Biomed 53(5):1305-1312 

  31. Pharmacogenomics F Thomas 11 12 1751 2010 10.2217/pgs.10.170 Thomas F, Hoskins JM, Dvorak A, Tan BR, McLeod HL (2010) Detection of the G > C SNP and rare mutations in the 28-bp repeat of TYMS using gel-based capillary electrophoresis. Pharmacogenomics 11(12):1751-1756 

  32. Chin J Anal Chem XH Xie 39 11 1695 2011 Xie XH, Wang R, Jia ZP, Xie H, Zhang AM, Xu J, Wang XL, Wang XH (2011) Determination of mutation of C-myc oncogene in gastric cancer by capillary electrophoresis. Chin J Anal Chem 39(11):1695-1700 

  33. Biomed Chromatogr R Wang 26 3 393 2012 10.1002/bmc.1673 Wang R, Xie H, Xu YB, Jia ZP, Meng XD, Zhang JH, Ma J, Wang J, Wang XH (2012) Study on detection of mutation DNA fragment in gastric cancer by restriction endonuclease fingerprinting with capillary electrophoresis. Biomed Chromatogr 26(3):393-399 

  34. Chin J Anal Chem Y Liu 37 10 1494 2009 Liu Y, Wang R, Gao L, Jia ZP, Xin XT, Xie H, Ma J (2009) Methodology research on P53 gene mutation detection exon 7 of lung cancer by capillary electrophoresis with single strand conformation polymorphism and restriction fragment length polymorphism. Chin J Anal Chem 37(10):1494-1498 

  35. Electrophoresis TH Yang 33 17 2769 2012 10.1002/elps.201200246 Yang TH, Ou DL, Hsu C, Huang SH, Chang PL (2012) Comparative microRNA detection from precursor-microRNA-transfected hepatocellular carcinoma cells by capillary electrophoresis with dual-color laser-induced fluorescence. Electrophoresis 33(17):2769-2776 

  36. Anal Methods A Kotani 4 1 58 2012 10.1039/C1AY05366C Kotani A, Witek MA, Osiri JK, Wang H, Sinville R, Pincas H, Barany F, Soper SA (2012) EndoV/DNA ligase mutation scanning assay using microchip capillary electrophoresis and dual-color laser-induced fluorescence detection. Anal Methods 4(1):58-64 

  37. Electrophoresis PL Chang 32 9 1080 2011 10.1002/elps.201000445 Chang PL, Chiu TC, Wang TE, Hu KC, Tsai YH, Hu CC, Bair MJ, Chang HT (2011) Quantitation of branched-chain amino acids in ascites by capillary electrophoresis with light-emitting diode-induced fluorescence detection. Electrophoresis 32(9):1080-1083 

  38. J Chromatogr A YY Kao 1217 4 582 2010 10.1016/j.chroma.2009.11.069 Kao YY, Liu KT, Huang MF, Chiu TC, Chang HT (2010) Analysis of amino acids and biogenic amines in breast cancer cells by capillary electrophoresis using polymer solutions containing sodium dodecyl sulfate. J Chromatogr A 1217(4):582-587 

  39. Lab Chip WC Yang 10 19 2527 2010 10.1039/c005288d Yang WC, Yu M, Sun XH, Woolley AT (2010) Microdevices integrating affinity columns and capillary electrophoresis for multibiomarker analysis in human serum. Lab Chip 10(19):2527-2533 

  40. J Chromatogr A J Mbuna 1218 25 3923 2011 10.1016/j.chroma.2011.04.046 Mbuna J, Kaneta T, Imasaka T (2011) Rapid determination of multidrug resistance-associated protein in cancer cells by capillary electrophoresis immunoassay. J Chromatogr A 1218(25):3923-3927 

  41. J Chromatogr A LC Soliman 1267 162 2012 10.1016/j.chroma.2012.07.021 Soliman LC, Hui Y, Hewavitharana AK, Chen DDY (2012) Monitoring potential prostate cancer biomarkers in urine by capillary electrophoresis-tandem mass spectrometry. J Chromatogr A 1267:162-169 

  42. Gastroenterol Res Pract JL Chen 2012 1 2012 Chen JL, Fan J, Yan LS, Guo HQ, Xiong JJ, Ren Y, Hu JD (2012) Urine metabolite profiling of human colorectal cancer by capillary electrophoresis mass spectrometry based on MRB. Gastroenterol Res Pract 2012:1-8 

  43. Electrophoresis R Lee 31 14 2328 2010 10.1002/elps.200900451 Lee R, Britz-McKibbin P (2010) Metabolomic studies of radiation-induced apoptosis of human leukocytes by capillary electrophoresis-mass spectrometry and flow cytometry: adaptive cellular responses to ionizing radiation. Electrophoresis 31(14):2328-2337 

  44. Metabolomics M Sugimoto 6 1 78 2010 10.1007/s11306-009-0178-y Sugimoto M, Wong DT, Hirayama A, Soga T, Tomita M (2010) Capillary electrophoresis mass spectrometry-based saliva metabolomics identified oral, breast and pancreatic cancer-specific profiles. Metabolomics 6(1):78-95 

  45. Electrophoresis S Ongay 31 19 3314 2010 10.1002/elps.201000244 Ongay S, Martin-Alvarez PJ, Neususs C, de Frutos M (2010) Statistical evaluation of CZE-UV and CZE-ESI-MS data of intact alpha-1-acid glycoprotein isoforms for their use as potential biomarkers in bladder cancer. Electrophoresis 31(19):3314-3325 

  46. J Chromatogr B Anal Technol Biomed Life Sci A Cavazza 879 25 2501 2011 10.1016/j.jchromb.2011.06.048 Cavazza A, Corradini C, Marini M, Roda LG, Valenti A (2011) Capillary electrophoresis coupled with mass spectrometry for the evaluation of Substance P enzymatic degradation by SaOS-2 human osteosarcoma. J Chromatogr B Anal Technol Biomed Life Sci 879(25):2501-2506 

  47. Biotechnol Lett M Lei 34 9 1617 2012 10.1007/s10529-012-0945-0 Lei M, Chen DD, Deng XJ, Liu J, Chen LY, Liu YL, Li B, Yao HC, Xiong GM, Cao Y, Yang JH, Qi C (2012) Dynamic sieving capillary electrophoresis analysis of xylitol selenite-induced apoptosis in SMMC-7221 cells. Biotechnol Lett 34(9):1617-1621 

  48. Epigenetics AM Krais 6 5 560 2011 10.4161/epi.6.5.15678 Krais AM, Park YJ, Plass C, Schmeiser HH (2011) Determination of genomic 5-hydroxymethyl-2′-deoxycytidine in human DNA by capillary electrophoresis with laser-induced fluorescence. Epigenetics 6(5):560-565 

  49. Electrophoresis M Cornelius 26 2591 2005 10.1002/elps.200410405 Cornelius M, Wörth C, Kliem HC, Wiessler M, Schmeiser HH (2005) Detection and separation of nucleoside-5′-monophosphates of DNA by conjugation with the fluorescent dye BODIPY and capillary electrophoresis with laser-induced fluorescence detection. Electrophoresis 26:2591-2598 

  50. Electrophoresis Y Ma 25 1473 2004 10.1002/elps.200405895 Ma Y, Liu G, Du M, Stayton I (2004) Recent developments in the determination of urinary cancer biomarkers by capillary electrophoresis. Electrophoresis 25:1473-1484 

  51. Ann N Y Acad Sci M Verma 945 103 2001 10.1111/j.1749-6632.2001.tb03870.x Verma M, Wright GL, Hanash SM, GopalSrivastava R, Srivastava S (2001) Proteomic approaches within the NCI early detection research network for the discovery and identification of cancer biomarkers. Ann N Y Acad Sci 945:103-115 

  52. Nature A Sreekumar 457 910 2009 10.1038/nature07762 Sreekumar A, Poisson LM, Rajendiran TM, Khan AP, Cao Q, Yu J, Laxman B, Mehra R, Lonigro RJ, Li Y, Nyati MK, Ahsan A, Kalyana-Sundaram S, Han B, Cao X, Byun J, Omenn GS, Ghosh D, Pennathur S, Alexander DC, Berger A, Shuster JR, Wei JT, Varambally S, Beecher C, Chinnaiyan AM (2009) Metabolomic profiles delineate potential role for sarcosine in prostate cancer progression. Nature 457:910-914 

  53. Clin Chim Acta T Vermassen 413 1500 2012 10.1016/j.cca.2012.06.007 Vermassen T, Speeckaert M, Lumen N, Rottey S, Delanghe JR (2012) Glycosylation of prostate specific antigen and its potential diagnostic applications. Clin Chim Acta 413:1500-1505 

  54. Talanta W Zhu 78 1194 2009 10.1016/j.talanta.2009.01.054 Zhu W, Zhang W, Fan LY (2009) Study on mechanism of stacking of zwitterion in high saline biological sample by transient moving reaction boundary created by formic acid buffer and conjugate base in capillary electrophoresis. Talanta 78:1194-1200 

  55. Clin Chem SFY Li 52 137 2006 Li SFY, Krick LJ (2006) Clinical analysis by microchip capillary electrophoresis. Clin Chem 52:137-145 

  56. Electrophoresis F Shang 33 1 105 2012 10.1002/elps.201100454 Shang F, Guihen E, Glennon JD (2012) Recent advances in miniaturisation-the role of microchip electrophoresis in clinical analysis. Electrophoresis 33(1):105-116 

  57. J Pharm Biomed F Kitagawa 55 668 2011 10.1016/j.jpba.2010.11.013 Kitagawa F, Otsuka K (2011) Recent progress in microchip electrophoresis-mass spectrometry. J Pharm Biomed 55:668-678 

  58. Microfluid Nanofluid PS Nunes 9 145 2010 10.1007/s10404-010-0605-4 Nunes PS, Ohlsson PD, Ordeig O, Kutter JP (2010) Cyclic olefin polymers: emerging materials for lab-on-a-chip applications. Microfluid Nanofluid 9:145-161 

  59. Anal Chem T Sikanen 79 9135 2007 10.1021/ac071531+ Sikanen T, Tuomikoski S, Ketola RA, Kostiainen R, Franssila S, Kotiaho T (2007) Fully microfabricated and integrated SU-8-based capillary electrophoresis-electrospray ionization microchips for mass spectrometry. Anal Chem 79:9135-9144 

  60. Electrophoresis V Dolnik 21 41 2000 10.1002/(SICI)1522-2683(20000101)21:1<41::AID-ELPS41>3.0.CO;2-7 Dolnik V, Liu S, Jovanovich S (2000) Capillary electrophoresis on microchip. Electrophoresis 21:41-54 

  61. Anal Chem JI Molho 73 1350 2001 10.1021/ac001127+ Molho JI, Herr AE, Mosier BP, Santiago JG, Kenny TW, Brennen RA, Gordon GB, Mohammadi A (2001) Optimization of turn geometries for microchip electrophoresis. Anal Chem 73:1350-1360 

  62. Electrophoresis Z Zhuang 32 2 246 2011 10.1002/elps.201000461 Zhuang Z, Mitra I, Hussein A, Novotny MV, Mechref Y, Jacobson SC (2011) Microchip electrophoresis of N-glycans on serpentine separation channels with asymmetrically tapered turns. Electrophoresis 32(2):246-253 

  63. Anal Chem M Benhabib 82 6 2372 2010 10.1021/ac9025994 Benhabib M, Chiesl TN, Stockton AM, Scherer JR, Mathies RA (2010) Multichannel capillary electrophoresis microdevice and instrumentation for in situ planetary analysis of organic molecules and biomarkers. Anal Chem 82(6):2372-2379 

  64. Electrophoresis K Ohno 29 4443 2008 10.1002/elps.200800121 Ohno K, Tachikawa K, Manz A (2008) Microfluidics: applications for analytical purposes in chemistry and biochemistry. Electrophoresis 29:4443-4453 

  65. Electrophoresis WR Vandaveer 25 3528 2004 10.1002/elps.200406115 Vandaveer WR, Pasas-Farmer SA, Fischer DJ, Frankenfeld CN, Lunte SM (2004) Recent developments in electrochemical detection for microchip capillary electrophoresis. Electrophoresis 25:3528-3549 

  66. Eur J Pharm Sci AJ Gawron 14 1 2001 10.1016/S0928-0987(01)00153-1 Gawron AJ, Martin RS, Lunte SM (2001) Microchip electrophoretic separation systems for biomedical and pharmaceutical analysis. Eur J Pharm Sci 14:1-12 

  67. Anal Chem JC Albrecht 83 509 2011 10.1021/ac102188p Albrecht JC, Lin JS, Barron A (2011) A 265-base DNA sequencing read by capillary electrophoresis with no separation matrix. Anal Chem 83:509-515 

  68. Electroanalysis JC Albrecht 34 590 2013 Albrecht JC, Kotani A, Lin JS, Soper SA, Barron AE (2013) Simultaneous detection of 19 K-ras mutations by free-solution conjugate electrophoresis of ligase detection reaction products on glass microchips. Electroanalysis 34:590-597 

  69. Electrophoresis JC Albrecht 32 10 1201 2011 10.1002/elps.201000574 Albrecht JC, Kerby MB, Niedringhaus TP, Lin JS, Wang X, Barron AE (2011) Free-solution electrophoretic separations of DNA-drag-tag conjugates on glass microchips with no polymer network and no loss of resolution at increased electric field strength. Electrophoresis 32(10):1201-1208 

  70. Electrophoresis WR Vandaveer IV 23 3667 2002 10.1002/1522-2683(200211)23:21<3667::AID-ELPS3667>3.0.CO;2-W Vandaveer WR IV, Pasas SA, Martin RS, Lunte SM (2002) Recent developments in amperometric detection for microchip capillary electrophoresis. Electrophoresis 23:3667-3677 

  71. Electrophoresis M Pumera 32 8 793 2011 10.1002/elps.201190021 Pumera M, Escarpa A (2011) Electrochemistry in microfluidics and capillary electrophoresis. Electrophoresis 32(8):793-794 

  72. Electrophoresis M Pumera 30 3315 2009 10.1002/elps.200900008 Pumera M, Escarpa A (2009) Nanomaterials as electrochemical detectors in microfluidics and CE: fFundamentals, designs, and applications. Electrophoresis 30:3315-3323 

  73. Anal Chim Acta Y Liu 650 1 77 2009 10.1016/j.aca.2009.06.048 Liu Y, Wang H, Huang J, Yang J, Liu B, Yang P (2009) Microchip-based ELISA strategy for the detection of low-level disease biomarker in serum. Anal Chim Acta 650(1):77-82 

  74. MRS Bull BA Simmons 31 120 2006 10.1557/mrs2006.26 Simmons BA, Mcgraw GJ, Davalos RV, Fiechtner GJ, Fintschenko Y, Cummings EB (2006) The development of polymeric devices as dielectrophoretic separators and concentrators. MRS Bull 31:120-124 

  75. Anal Chem BH Lapizco-Encinas 76 1571 2004 10.1021/ac034804j Lapizco-Encinas BH, Simmons BA, Cummings EB, Fintschenko Y (2004) Dielectrophoretic concentration and separation of live and dead bacteria in an array of insulators. Anal Chem 76:1571-1579 

  76. Electrophoresis BH Lapizco-Encinas 25 1695 2004 10.1002/elps.200405899 Lapizco-Encinas BH, Simmons BA, Cummings EB, Fintschenko Y (2004) Insulator-based dielectrophoresis for the selective concentration and separation of live bacteria in water. Electrophoresis 25:1695-1704 

  77. J Microbiol Methods BH Lapizco-Encinas 62 317 2005 10.1016/j.mimet.2005.04.027 Lapizco-Encinas BH, Davalos RV, Simmons BA, Cummings EB, Fintschenko Y (2005) An insulator-based (electrodeless) dielectrophoretic concentrator for microbes in water. J Microbiol Methods 62:317-326 

  78. Sensors CH Chuang 11 11 11021 2011 10.3390/s111111021 Chuang CH, Huang YW, Wu YT (2011) System-level biochip for impedance sensing and programmable manipulation of bladder cancer cells. Sensors 11(11):11021-11035. doi: 10.3390/s111111021 

  79. J Am Soc Mass Spectrom AD Zamfir 22 12 2145 2011 10.1007/s13361-011-0250-5 Zamfir AD, Serb A, Vukeli Z, Flangea C, Schiopu C, Fabris D, Kalanj-Bognar S, Capitan F, Sisu E (2011) Assessment of the molecular expression and structure of gangliosides in brain metastasis of lung adenocarcinoma by an advanced approach based on fully automated chip-nanoelectrospray mass spectrometry. J Am Soc Mass Spectrom 22(12):2145-2159 

  80. Eur Urol PJ Bastiana 46 6 698 2004 10.1016/j.eururo.2004.07.022 Bastiana PJ, Yegnasubramanian S, Palapattua GS, Rogersa CG, Lin X, De Marzo AM, Nelson WG (2004) Molecular biomarker in prostate cancer: the role of CpG island hypermethylation. Eur Urol 46(6):698-708 

  81. J Surg Oncol M Jain 106 549 2012 10.1002/jso.23119 Jain M, Rechache N, Kebebew E (2012) Molecular markers of adrenocortical tumors. J Surg Oncol 106:549-556 

  82. Eur J Pharmacol E Wiechec 625 122 2009 10.1016/j.ejphar.2009.08.045 Wiechec E, Hansen LL (2009) The effect of genetic variability on drug response in conventional breast cancer treatment. Eur J Pharmacol 625:122-130 

  83. Clin Cancer Res YP Lim 11 3163 2005 10.1158/1078-0432.CCR-04-2243 Lim YP (2005) Mining the tumor phosphoproteome for cancer markers. Clin Cancer Res 11:3163-3169 

  84. J Mol Med ODK Maddocks 89 237 2011 10.1007/s00109-011-0735-5 Maddocks ODK, Vousden KH (2011) Metabolic regulation by p53. J Mol Med 89:237-245 

  85. Anal Bioanal Chem A Zinellu 399 3 1181 2011 10.1007/s00216-010-4417-x Zinellu A, Sotgia S, De Murtas V, Cossu-Rocca P, De Miglio MR, Muroni MR, Mura A, Uras MG, Contini M, Deiana L, Carru C (2011) Evaluation of methylation degree from formalin-fixed paraffin-embedded DNA extract by field-amplified sample injection capillary electrophoresis with UV detection. Anal Bioanal Chem 399(3):1181-1186 

  86. Electrophoresis MC Huang 33 5 788 2012 10.1002/elps.201100460 Huang MC, Cheong WC, Lim LS, Li MH (2012) A simple, high sensitivity mutation screening using Ampligase mediated T7 endonuclease I and Surveyor nuclease with microfluidic capillary electrophoresis. Electrophoresis 33(5):788-796 

  87. Lab Investig HD Zhang 91 5 788 2011 10.1038/labinvest.2010.200 Zhang HD, Wang XN, Ma Q, Zhou Z, Fang J (2011) Rapid detection of low-abundance K-ras mutation in stools of colorectal cancer patients using chip-based temperature gradient capillary electrophoresis. Lab Investig 91(5):788-798 

  88. Cancer Y Jiang 115 3609 2009 10.1002/cncr.24434 Jiang Y, Kimchi E, Staveley-O’carroll K (2009) Assessment of K-ras mutation: a step toward personalized medicine for patients with colorectal cancer. Cancer 115:3609-3617 

  89. Acta Chim Sin Y Liu 69 5 543 2011 Liu Y, Wang R, Gao L, Jia ZP, Xie H, Zhang JL, Ma J, Zhang AM, Xie XH (2011) Capillary electrophoresis detection of lung cancer and adjacent normal tissue differences in protein mixture. Acta Chim Sin 69(5):543-547 

  90. Urol Clin N Am CR Pound 24 395 1997 10.1016/S0094-0143(05)70386-4 Pound CR, Partin AW, Epstein JI, Walsh PC (1997) Prostate-specific antigen after anatomic radical retropubic prostatectomy. Patterns of recurrence and cancer control. Urol Clin N Am 24:395-406 

  91. Int J Electrochem Sci L Krejcova 7 3 1767 2012 10.1016/S1452-3981(23)13839-9 Krejcova L, Fabrik I, Hynek D, Krizkova S, Gumulec J, Ryvolova M, Adam V, Babula P, Trnkova L, Stiborova M, Hubalek J, Masarik M, Binkova H, Eckschlager T, Kizek R (2012) Metallothionein electrochemically determined using Brdicka reaction as a promising blood marker of head and neck malignant tumours. Int J Electrochem Sci 7(3):1767-1784 

  92. J Chromatogr A M Ryvolova 1226 24 31 2012 10.1016/j.chroma.2011.10.015 Ryvolova M, Adam V, Kizek R (2012) Analysis of metallothionein by capillary electrophoresis. J Chromatogr A 1226(24):31-42 

  93. Electrophoresis M Ryvolova 33 2 270 2012 10.1002/elps.201100312 Ryvolova M, Hynek D, Skutkova H, Adam V, Provaznik I, Kizek R (2012) Structural changes in metallothionein isoforms revealed by capillary electrophoresis and Brdicka reaction. Electrophoresis 33(2):270-279 

  94. Electrophoresis S Krizkova 32 15 1952 2011 10.1002/elps.201000519 Krizkova S, Ryvolova M, Gumulec J, Masarik M, Adam V, Majzlik P, Hubalek J, Provaznik I, Kizek R (2011) Electrophoretic fingerprint metallothionein analysis as a potential prostate cancer biomarker. Electrophoresis 32(15):1952-1961 

  95. Science O Warburg 123 3191 309 1956 10.1126/science.123.3191.309 Warburg O (1956) On the origin of cancer cells. Science 123(3191):309-314 

  96. Metabolomics K Kami 9 444 2013 10.1007/s11306-012-0452-2 Kami K, Fujimori T, Sato H, Sato M, Yamamoto H, Ohashi Y, Sugiyama N, Ishihama Y, Onozuka H, Ochiai A, Esumi H, Soga T, Tomita M (2013) Metabolomic profiling of lung and prostate tumor tissues by capillary electrophoresis time-of-flight mass spectrometry. Metabolomics 9:444-453 

  97. Cancer Res A Hirayama 69 4918 2009 10.1158/0008-5472.CAN-08-4806 Hirayama A, Kami K, Sugimoto M, Sugawara M, Toki N, Onozuka H (2009) Quantitative metabolome profiling of colon and stomach cancer microenvironment by capillary electrophoresis time-of-flight mass spectrometry. Cancer Res 69:4918-4925 

  98. Chromatographia SF Wang 70 1479 2009 10.1365/s10337-009-1319-1 Wang SF, Yang P, Zhao XP (2009) Amino acid profile determination in the urine of bladder cancer patients by CE-MS with on-Line pH-mediated stacking and pattern recognition. Chromatographia 70:1479-1484 

  99. Cancer Res AJ Smith 54 5527 1994 Smith AJ, Stern HS, Penner M, Hay K, Mirei A, Bapat BV, Gallinger S (1994) Somatic APC and K-ras codon 12 mutations in aberrant crypt foci from human colons. Cancer Res 54:5527-5530 

  100. Br J Cancer J Breivik 69 367 1994 10.1038/bjc.1994.67 Breivik J, Meling GI, Spurkland A, Rognum TO, Gaudernack G (1994) K-ras mutation in colorectal cancer: relations to patient age, sex, and tumour location. Br J Cancer 69:367-371 

  101. Nature K Forrester 327 298 1987 10.1038/327298a0 Forrester K, Almoguera C, Han K, Grizzle WE, Perucho M (1987) Frequent mutation of histone-modifying genes in non-Hodgkin lymphoma. Nature 327:298-303 

  102. Biosens Bioelectron M Hashimoto 21 1915 2006 10.1016/j.bios.2006.01.014 Hashimoto M, Barany F, Soper SA (2006) Polymerase chain reaction/ligase detection reaction/hybridization assays using flow-through microfluidic devices for the detection of low-abundant DNA point mutations. Biosens Bioelectron 21:1915-1923 

  103. Electrophoresis G Thomas 25 1668 2004 10.1002/elps.200405886 Thomas G, Sinville R, Sutton S, Farquar H, Hammer RP, Sper SA, Cheng Y, Barany F (2004) Capillary and microelectrophoretic separations of ligase detection reaction products produced from low-abundant point mutations in genomic DNA. Electrophoresis 25:1668-1677 

  104. Clin Biochem M Khanna 32 287 1999 10.1016/S0009-9120(99)00020-X Khanna M, Cao WG, Zirvi M, Paty P, Barany F (1999) Ligase detection reaction for identification of low abundance mutations. Clin Biochem 32:287-290 

  105. Analyst M Hashimoto 132 913 2007 10.1039/b700071e Hashimoto M, Barany F, Xu F, Soper SA (2007) Serial processing of biological reactions using flow-through microfluidic devices: coupled PCR/LDR for the detection of low-abundant DNA point mutations. Analyst 132:913-921 

  106. Hepatology TO Lankisch 53 3 875 2011 10.1002/hep.24103 Lankisch TO, Metzger J, Negm AA, Vosskuhl K, Schiffer E, Siwy J, Weismuller TJ, Schneider AS, Thedieck K, Baumeister R, Zurbig P, Weissinger EM, Manns MP, Mischak H, Wedemeyer J (2011) Bile proteomic profiles differentiate cholangiocarcinoma from primary sclerosing cholangitis and choledocholithiasis. Hepatology 53(3):875-884 

  107. Gut J Metzger 62 1 122 2013 10.1136/gutjnl-2012-302047 Metzger J, Negm AA, Plentz RR, Weismuller TJ, Wedemeyer J, Karlsen TH, Dakna M, Mullen W, Mischak H, Manns MP, Lankisch TO (2013) Urine proteomic analysis differentiates cholangiocarcinoma from primary sclerosing cholangitis and other benign biliary disorders. Gut 62(1):122-130 

  108. Talanta B Huang 85 1 333 2011 10.1016/j.talanta.2011.03.066 Huang B, Huang C, Liu P, Wang F, Na N, Ouyang J (2011) Fast haptoglobin phenotyping based on microchip electrophoresis. Talanta 85(1):333-338 

  109. Dig Liver Dis B Blomme 44 4 315 2012 10.1016/j.dld.2011.10.015 Blomme B, Francque S, Trepo E, Libbrecht L, Vanderschaeghe D, Verrijken A, Pattyn P, Nieuwenhove YV, Putte DV, Geerts A, Colle I, Delanghe J, Moreno C, Gaal LV, Callewaert N, Vlierberghe HV (2012) N-glycan based biomarker distinguishing nonalcoholic steatohepatitis from steatosis independently of fibrosis. Dig Liver Dis 44(4):315-322 

  110. Rinsho Byori S Sato 58 12 1155 2010 Sato S, Toyota J, Kagebayashi C, Kurosawa T, Watanabe M, Satomura S (2010) Evaluation of a new, microfluidic chip-based immunoassay for measurement of AFP-L3. Rinsho Byori 58(12):1155-1161 

  111. Eur J Clin Investig XM Xu 42 7 751 2012 10.1111/j.1365-2362.2011.02641.x Xu XM, Qian JC, Cai Z, Tang T, Wang P, Zhang KH, Deng ZL, Cai JP (2012) DNA alterations of microsatellite DNA, p53, APC, and K-ras in chinese colorectal cancer patients. Eur J Clin Investig 42(7):751-759 

  112. Cancer Epidemiol A Nikolic 35 3 265 2011 10.1016/j.canep.2010.10.002 Nikolic A, Kojic S, Knezevic S, Krivokapic Z, Ristanovic M, Radojkovic D (2011) Structural and functional analysis of SMAD4 gene promoter in malignant pancreatic and colorectal tissues: detection of two novel polymorphic nucleotide repeats. Cancer Epidemiol 35(3):265-271 

  113. Appl Immunohistochem Mol Morphol S Wu 20 5 512 2012 10.1097/PAI.0b013e3182434174 Wu S, Qian X, Yu X, Sheng H, Lu B (2012) Microwave heating of long-term formalin-fixed surgical pathology specimens improves quality of extracted DNA. Appl Immunohistochem Mol Morphol 20(5):512-517 

  114. Prog Biochem Biophys HD Zhang 37 7 794 2010 10.3724/SP.J.1206.2010.00029 Zhang HD, Wang XN, Zhou Z, Ma Q, Fang J (2010) Mutation detection of K-ras gene in paraffin-embedded colorectal cancer tissues by using chip-based TGCE. Prog Biochem Biophys 37(7):794-800 

  115. Anal Chem U Dharmasiri 83 6 2301 2011 10.1021/ac103172y Dharmasiri U, Njoroge SK, Witek MA, Adebiyi MG, Kamande JW, Hupert ML, Barany F, Soper SA (2011) High-throughput selection, enumeration, electrokinetic manipulation, and molecular profiling of low-abundance circulating tumor cells using a microfluidic system. Anal Chem 83(6):2301-2309 

  116. Methods Mol Biol C Houdayer 653 147 2010 10.1007/978-1-60761-759-4_9 Houdayer C, Moncoutier V, Champ J, Weber J, Viovy JL, Stoppa-Lyonnet D (2010) Enhanced mismatch mutation analysis: simultaneous detection of point mutations and large scale rearrangements by capillary electrophoresis, application to BRCA1 and BRCA2. Methods Mol Biol 653:147-180 

  117. Clin Chem CJ Mattocks 56 4 593 2010 10.1373/clinchem.2009.135426 Mattocks CJ, Watkins G, Ward D, Janssens T, Bosgoed EAJ, van der Donk K, Ligtenberg MJ, Pot B, Theelen J, Cross NCP, Scheffer H, Matthijs G (2010) Interlaboratory diagnostic validation of conformation-sensitive capillary electrophoresis for mutation scanning. Clin Chem 56(4):593-602 

  118. Anal Chem BJ Dodgson 84 13 5470 2012 10.1021/ac301546p Dodgson BJ, Mazouchi A, Wegman DW, Gradinaru CC, Krylov SN (2012) Detection of a thousand copies of miRNA without enrichment or modification. Anal Chem 84(13):5470-5474 

  119. Hum Mutat V Caux-Moncoutier 32 3 325 2011 10.1002/humu.21414 Caux-Moncoutier V, Castera L, Tirapo C, Michaux D, Remon MA, Lauge A, Rouleau E, De Pauw A, Buecher B, Gauthier-Villars M, Viovy JL, Stoppa-Lyonnet D, Houdayer C (2011) EMMA, a cost- and time-effective diagnostic method for simultaneous detection of point mutations and large-scale genomic rearrangements: application to BRCA1 and BRCA2 in 1525 patients. Hum Mutat 32(3):325-334 

  120. Electrophoresis R Garrido-Medina 32 15 2036 2011 10.1002/elps.201000524 Garrido-Medina R, Diez-Masa JC, de Frutos M (2011) CE methods for analysis of isoforms of prostate-specific antigen compatible with online derivatization for LIF detection. Electrophoresis 32(15):2036-2043 

  121. Clin Chim Acta FG Ye 411 15/16 1058 2010 Ye FG, Shi M, Huang Y, Zhao SL (2010) Noncompetitive immunoassay for carcinoembryonic antigen in human serum by microchip electrophoresis for cancer diagnosis. Clin Chim Acta 411(15/16):1058-1062 

  122. Hepatogastroenterology JX Hou 58 106 632 2011 Hou JX, Yang XQ, Chen C, Jiang Q, Yang GL, Li Y (2011) Screening the gastric cancer related tumor markers from multi-tumor markers protein chip with kappa coefficient and cost-effectiveness analysis. Hepatogastroenterology 58(106):632-636 

  123. Hepatogastroenterology B Fan 58 239 2011 Fan B, Xiong B (2011) Investigation of serum tumor markers in the diagnosis of gastric cancer. Hepatogastroenterology 58:239-245 

  124. Electrophoresis S Zhao 27 461 2006 10.1002/elps.200500300 Zhao S, Yuan H, Xiao D (2006) Optical fiber light-emitting diode-induced fluorescence detection for capillary electrophoresis. Electrophoresis 27:461-467 

  125. Electrophoresis LM Ramsay 30 297 2009 10.1002/elps.200800498 Ramsay LM, Dickerson JA, Dovichi NJ (2009) Attomole protein analysis by CIEF with LIF detection. Electrophoresis 30:297-302 

  126. Dig Dis Sci Y Tamura 55 12 3576 2010 10.1007/s10620-010-1222-5 Tamura Y, Igarashi M, Kawai H, Suda T, Satomura S, Aoyagi Y (2010) Clinical advantage of highly sensitive on-chip immunoassay for fucosylated fraction of alpha-fetoprotein in patients with hepatocellular carcinoma. Dig Dis Sci 55(12):3576-3583 

  127. Cancer Sci H Toyoda 102 5 1025 2012 10.1111/j.1349-7006.2011.01875.x Toyoda H, Kumada T, Tada T, Kaneoka Y, Maeda A, Kanke F, Satomura S (2012) Clinical utility of highly sensitive Lens culinaris agglutinin-reactive alpha-fetoprotein in hepatocellular carcinoma patients with alpha-fetoprotein <20 ng/mL. Cancer Sci 102(5):1025-1031 

  128. J Pharm Biomed U Franzen 55 1 16 2011 10.1016/j.jpba.2010.12.037 Franzen U, Nguyen TT, Vermehren C, Gammelgaard B, Ostergaard J (2011) Characterization of a liposome-based formulation of oxaliplatin using capillary electrophoresis: encapsulation and leakage. J Pharm Biomed 55(1):16-22 

  129. Platelets D Provaznikova 19 471 2008 10.1080/09537100802140013 Provaznikova D, Kumstyrova T, Kotlin R, Salaj P, Matoska V, Hrachovinova I, Rittich S (2008) High resolution melting analysis for detection of MYH9 mutations. Platelets 19:471-475 

  130. Genomics H Davies 87 427 2006 10.1016/j.ygeno.2005.11.008 Davies H, Dicks E, Stephens P, Cox C, Teague J, Greenman C (2006) High throughput DNA sequence variant detection by conformation sensitive capillary electrophoresis and automated peak comparison. Genomics 87:427-432 

  131. J Mol Diagn S Vermeer 11 514 2009 10.2353/jmoldx.2009.090059 Vermeer S, Meijer R, Hofste T, Bodmer D, Bosgoed E, Cremers P, Kremer B, Knoers N, Scheffer H (2009) Design and validation of a conformation sensitive capillary electrophoresis-based mutation scanning system and automated data analysis of the more than 15 kbp-spanning coding sequence of the SACS gene. J Mol Diagn 11:514-523 

  132. Biomed Microdevices CH Chuang 14 2 271 2012 10.1007/s10544-011-9603-x Chuang CH, Huang YW, Wu YT (2012) Dielectrophoretic chip with multilayer electrodes and micro-cavity array for trapping and programmably releasing single cells. Biomed Microdevices 14(2):271-278 

  133. Nat Biotechnol V Ozdemir 24 942 2006 10.1038/nbt0806-942 Ozdemir V, Bryn W, Glatt SJ, Tsuang MT, Lohr JB, Reist C (2006) Shifting emphasis from pharmacogenomics to theranostics. Nat Biotechnol 24:942-946 

  134. Pharmacogenomics J BS Shastry 6 16 2006 10.1038/sj.tpj.6500338 Shastry BS (2006) Pharmacogenetics and the concept of individualized medicine. Pharmacogenomics J 6:16-21 

  135. Cancer J Sci Am EM Jaffee 4 194 1998 Jaffee EM, Schutte M, Gossett J, Morsberger LA, Adler AJ, Thomas M, Greten TF, Hruban RH (1998) Development and characterization of a cytokine-secreting pancreatic adenocarcinoma vaccine from primary tumors for use in clinical trials. Cancer J Sci Am 4:194-203 

  136. Biotechniques MT Lin 48 3 211 2010 10.2144/000113363 Lin MT, Tseng LH, Kamiyama H, Kamiyama M, Lim P, Hidalgo M, Wheelan S, Eshleman J (2010) Quantifying the relative amount of mouse and human DNA in cancer xenografts using species-specific variation in gene length. Biotechniques 48(3):211-218 

  137. Ann Surg Oncol U Rudloff 17 8 2229 2010 10.1245/s10434-010-0959-6 Rudloff U, Bhanot U, Gerald W, Klimstra DS, Jarnagin WR, Brennan MF, Allen PJ (2010) Biobanking of human pancreas cancer tissue: impact of ex-vivo procurement times on RNA quality. Ann Surg Oncol 17(8):2229-2236 

  138. Anticancer Res ZH Sun 24 1159 2004 Sun ZH, Fu XL, Zhang L, Yang X, Liu F, Hu G (2004) A protein chip system for parallel analysis of multi-tumor markers and its application in cancer detection. Anticancer Res 24:1159-1166 

  139. J Postgrad Med C Chen 54 186 2008 10.4103/0022-3859.40963 Chen C, Chen LQ, Yang GL, Li Y (2008) The application of C12 biochip in the diagnosis and monitoring of colorectal cancer: systematic evaluation and suggestion for improvement. J Postgrad Med 54:186-190 

  140. Anal Chem I Mitra 84 8 3621 2012 10.1021/ac203431s Mitra I, Zhuang Z, Zhang Y, Yu CY, Hammoud ZT, Tang H, Mechref Y, Jacobson SC (2012) N-glycan profiling by microchip electrophoresis to differentiate disease states related to esophageal adenocarcinoma. Anal Chem 84(8):3621-3627 

  141. Anal Chem RA Evangelista 67 2239 1995 10.1021/ac00109a051 Evangelista RA, Liu MS, Chen FT (1995) Characterization of 9-aminopyrene-1,4,6-trisulfonate derivatized sugars by capillary electrophoresis with laser-induced fluorescence detection. Anal Chem 67:2239-2245 

섹션별 컨텐츠 바로가기

AI-Helper ※ AI-Helper는 오픈소스 모델을 사용합니다.

AI-Helper 아이콘
AI-Helper
안녕하세요, AI-Helper입니다. 좌측 "선택된 텍스트"에서 텍스트를 선택하여 요약, 번역, 용어설명을 실행하세요.
※ AI-Helper는 부적절한 답변을 할 수 있습니다.

선택된 텍스트

맨위로