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Infusion of ATP increases leg oxygen delivery but not oxygen uptake in the initial phase of intense knee‐extensor exercise in humans 원문보기

Experimental physiology, v.99 no.10, 2014년, pp.1399 - 1408  

Nyberg, Michael (Department of Nutrition, Exercise and Sports, University of Copenhagen, Copenhagen, Denmark) ,  Christensen, Peter M. (Department of Nutrition, Exercise and Sports, University of Copenhagen, Copenhagen, Denmark) ,  Mortensen, Stefan P. (Copenhagen Muscle Research Centre, Copenhagen, Denmark) ,  Hellsten, Ylva (Department of Nutrition, Exercise and Sports, University of Copenhagen, Copenhagen, Denmark) ,  Bangsbo, Jens (Department of Nutrition, Exercise and Sports, University of Copenhagen, Copenhagen, Denmark)

Abstract AI-Helper 아이콘AI-Helper

New FindingsWhat is the central question of this study?In the transition from rest to exercise, skeletal muscle blood flow, oxygen delivery and extraction of oxygen from the blood increase to accommodate the need for additional oxygen in the contracting fibres. To what extent skeletal muscle blood f...

참고문헌 (41)

  1. Andersen P & Saltin B ( 1985 ). Maximal perfusion of skeletal muscle in man . J Physiol 366 , 233 – 249 . 

  2. Bangsbo J , Krustrup P , González‐Alonso J , Boushel R & Saltin B ( 2000 ). Muscle oxygen kinetics at onset of intense dynamic exercise in humans . Am J Physiol Regul Integr Comp Physiol 279 , R899 – R906 . 

  3. Behnke BJ , McDonough P , Padilla DJ , Musch TI & Poole DC ( 2003 ). Oxygen exchange profile in rat muscles of contrasting fibre types . J Physiol 549 , 597 – 605 . 

  4. Broch‐Lips M , Pedersen TH & Nielsen OB ( 2010 ). Effect of purinergic receptor activation on Na + –K + pump activity, excitability, and function in depolarized skeletal muscle . Am J Physiol Cell Physiol 298 , C1438 – C1444 . 

  5. Calbet JA , Lundby C , Sander M , Robach P , Saltin B & Boushel R ( 2006 ). Effects of ATP‐induced leg vasodilation on V̇ O2 ?peak and leg O 2 extraction during maximal exercise in humans . Am J Physiol Regul Integr Comp Physiol 291 , R447 – R453 . 

  6. Christensen PM , Nordsborg NB , Nybo L , Mortensen SP , Sander M , Secher NH & Bangsbo J ( 2012 ). Thigh oxygen uptake at the onset of intense exercise is not affected by a reduction in oxygen delivery caused by hypoxia . Am J Physiol Regul Integr Comp Physiol 303 , R843 – R849 . 

  7. Christensen PM , Nyberg M , Mortensen SP , Nielsen JJ , Secher NH , Damsgaard R , Hellsten Y & Bangsbo J ( 2013 ). Leg oxygen uptake in the initial phase of intense exercise is slowed by a marked reduction in oxygen delivery . Am J Physiol Regul Integr Comp Physiol 305 , R313 – R321 . 

  8. Essen‐Gustavsson B & Henriksson J ( 1984 ). Enzyme levels in pools of microdissected human muscle fibres of identified type. Adaptive response to exercise . Acta Physiol Scand 120 , 505 – 515 . 

  9. Faisal A , Dyson KS & Hughson RL ( 2010 ). Prolonged ischaemia impairs muscle blood flow and oxygen uptake dynamics during subsequent heavy exercise . J Physiol 588 , 3785 – 3797 . 

  10. González‐Alonso J , Olsen DB & Saltin B ( 2002 ). Erythrocyte and the regulation of human skeletal muscle blood flow and oxygen delivery: role of circulating ATP . Circ Res 91 , 1046 – 1055 . 

  11. Goodwin ML , Hernández A , Lai N , Cabrera ME & Gladden LB ( 2012 ). V̇ O2 on‐kinetics in isolated canine muscle in situ during slowed convective O 2 delivery . J Appl Physiol 112 , 9 – 19 . 

  12. Grassi B , Gladden LB , Samaja M , Stary CM & Hogan MC ( 1998a ). Faster adjustment of O 2 delivery does not affect V̇ O2 on‐kinetics in isolated in situ canine muscle . J Appl Physiol 85 , 1394 – 1403 . 

  13. Grassi B , Gladden LB , Stary CM , Wagner PD & Hogan MC ( 1998b ). Peripheral O 2 diffusion does not affect V̇ O2 on‐kinetics in isolated in situ canine muscle . J Appl Physiol 85 , 1404 – 1412 . 

  14. Grassi B , Hogan MC , Kelley KM , Aschenbach WG , Hamann JJ , Evans RK , Patillo RE & Gladden LB ( 2000 ). Role of convective O 2 delivery in determining V̇ O2 on‐kinetics in canine muscle contracting at peak V̇ O2 . J Appl Physiol 89 , 1293 – 1301 . 

  15. Grassi B , Poole DC , Richardson RS , Knight DR , Erickson BK & Wagner PD ( 1996 ). Muscle O 2 uptake kinetics in humans: implications for metabolic control . J Appl Physiol 80 , 988 – 998 . 

  16. Grassi B , Rossiter HB , Hogan MC , Howlett RA , Harris JE , Goodwin ML , Dobson JL & Gladden LB ( 2011 ). Faster O 2 uptake kinetics in canine skeletal muscle in situ after acute creatine kinase inhibition . J Physiol 589 , 221 – 233 . 

  17. Jensen FB ( 2004 ). Red blood cell pH, the Bohr effect, and other oxygenation‐linked phenomena in blood O 2 and CO 2 transport . Acta Physiol Scand 182 , 215 – 227 . 

  18. Jones AM , Krustrup P , Wilkerson DP , Berger NJ , Calbet JA & Bangsbo J ( 2012 ). Influence of exercise intensity on skeletal muscle blood flow, O 2 extraction and O 2 uptake on‐kinetics . J Physiol 590 , 4363 – 4376 . 

  19. Juel C , Pilegaard H , Nielsen JJ & Bangsbo J ( 2000 ). Interstitial K + in human skeletal muscle during and after dynamic graded exercise determined by microdialysis . Am J Physiol Regul Integr Comp Physiol 278 , R400 – R406 . 

  20. Koga S , Poole DC , Shiojiri T , Kondo N , Fukuba Y , Miura A & Barstow TJ ( 2005 ). Comparison of oxygen uptake kinetics during knee extension and cycle exercise . Am J Physiol Regul Integr Comp Physiol 288 , R212 – R220 . 

  21. Krogh A & Lindhard J ( 1913 ). The regulation of respiration and circulation during the initial stages of muscular work . J Physiol 47 , 112 – 136 . 

  22. Krustrup P , Hellsten Y & Bangsbo J ( 2004a ). Intense interval training enhances human skeletal muscle oxygen uptake in the initial phase of dynamic exercise at high but not at low intensities . J Physiol 559 , 335 – 345 . 

  23. Krustrup P , Secher NH , Relu MU , Hellsten Y , Söderlund K & Bangsbo J ( 2008 ). Neuromuscular blockade of slow twitch muscle fibres elevates muscle oxygen uptake and energy turnover during submaximal exercise in humans . J Physiol 586 , 6037 – 6048 . 

  24. Krustrup P , Söderlund K , Mohr M & Bangsbo J ( 2004b ). The slow component of oxygen uptake during intense, sub‐maximal exercise in man is associated with additional fibre recruitment . Pflugers Arch 447 , 855 – 866 . 

  25. Krustrup P , Söderlund K , Mohr M , González‐Alonso J & Bangsbo J ( 2004c ). Recruitment of fibre types and quadriceps muscle portions during repeated, intense knee‐extensor exercise in humans . Pflugers Arch 449 , 56 – 65 . 

  26. Macdonald M , Pedersen PK & Hughson RL ( 1997 ). Acceleration of V̇ O2 kinetics in heavy submaximal exercise by hyperoxia and prior high‐intensity exercise . J Appl Physiol 83 , 1318 – 1325 . 

  27. MacDonald MJ , Shoemaker JK , Tschakovsky ME & Hughson RL ( 1998 ). Alveolar oxygen uptake and femoral artery blood flow dynamics in upright and supine leg exercise in humans . J Appl Physiol 85 , 1622 – 1628 . 

  28. McDonough P , Behnke BJ , Padilla DJ , Musch TI & Poole DC ( 2005 ). Control of microvascular oxygen pressures in rat muscles comprised of different fibre types . J Physiol 563 , 903 – 913 . 

  29. McKenna MJ , Bangsbo J & Renaud JM ( 2008 ). Muscle K + , Na + , and Cl − disturbances and Na + –K + pump inactivation: implications for fatigue . J Appl Physiol 104 , 288 – 295 . 

  30. Mortensen SP , González‐Alonso J , Bune LT , Saltin B , Pilegaard H & Hellsten Y ( 2009 ). ATP‐induced vasodilation and purinergic receptors in the human leg: roles of nitric oxide, prostaglandins, and adenosine . Am J Physiol Regul Integr Comp Physiol 296 , R1140 – R1148 . 

  31. Nyberg M , Mortensen SP , Saltin B , Hellsten Y & Bangsbo J ( 2010 ). Low blood flow at onset of moderate‐intensity exercise does not limit muscle oxygen uptake . Am J Physiol Regul Integr Comp Physiol 298 , R843 – R848 . 

  32. Paterson ND , Kowalchuk JM & Paterson DH ( 2005 ). Kinetics of V̇ O2 and femoral artery blood flow during heavy‐intensity, knee‐extension exercise . J Appl Physiol 99 , 683 – 690 . 

  33. Perrey S , Tschakovsky ME & Hughson RL ( 2001 ). Muscle chemoreflex elevates muscle blood flow and O 2 uptake at exercise onset in nonischemic human forearm . J Appl Physiol 91 , 2010 – 2016 . 

  34. Poole DC , Barstow TJ , McDonough P & Jones AM ( 2008 ). Control of oxygen uptake during exercise . Med Sci Sports Exerc 40 , 462 – 474 . 

  35. Poole DC & Jones AM ( 2012 ). Oxygen uptake kinetics . Compr Physiol 2 , 933 – 996 . 

  36. Rådegran G ( 1997 ). Ultrasound Doppler estimates of femoral artery blood flow during dynamic knee extensor exercise in humans . J Appl Physiol 83 , 1383 – 1388 . 

  37. Rådegran G & Saltin B ( 1998 ). Muscle blood flow at onset of dynamic exercise in humans . Am J Physiol Heart Circ Physiol 274 , H314 – H322 . 

  38. Rossiter HB ( 2011 ). Exercise: kinetic considerations for gas exchange . Compr Physiol 1 , 203 – 244 . 

  39. Walas H & Juel C ( 2012 ). Purinergic activation of rat skeletal muscle membranes increases V max and Na + affinity of the Na,K‐ATPase and phosphorylates phospholemman and α1 subunits . Pflugers Arch 463 , 319 – 326 . 

  40. Wilkerson DP , Berger NJ & Jones AM ( 2006 ). Influence of hyperoxia on pulmonary O 2 uptake kinetics following the onset of exercise in humans . Respir Physiol Neurobiol 153 , 92 – 106 . 

  41. Wilkerson DP , Rittweger J , Berger NJ , Naish PF & Jones AM ( 2005 ). Influence of recombinant human erythropoietin treatment on pulmonary O 2 uptake kinetics during exercise in humans . J Physiol 568 , 639 – 652 . 

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