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A rapid and sensitive LC‐MS/MS method for the determination of Pulsatilla saponin D in rat plasma and its application in a rat pharmacokinetic and bioavailability study

Biomedical chromatography : BMC, v.29 no.3, 2015년, pp.373 - 378  

Ouyang, Hui (Jiangxi University of Traditional Chinese Medicine, 56 Yangmin Road, Nanchang, 330006, China) ,  Guo, Yicheng (Jiangxi University of Traditional Chinese Medicine, 56 Yangmin Road, Nanchang, 330006, China) ,  He, Mingzhen (Jiangxi University of Traditional Chinese Medicine, 56 Yangmin Road, Nanchang, 330006, China) ,  Zhang, Jinlian (Jiangxi University of Traditional Chinese Medicine, 56 Yangmin Road, Nanchang, 330006, China) ,  Huang, Xiaofang (Jiangxi University of Traditional Chinese Medicine, 56 Yangmin Road, Nanchang, 330006, China) ,  Zhou, Xin (The Research Center for Quality Control of Natural Medicine, Guizhou Normal University, Guiyang, 550001, China) ,  Jiang, Hongliang (Tongji School of Pharmacy, Huazhong University of Science and Technology, 13 Hangkong Road, Wuhan, 430030, China) ,  Feng, Yulin (Jiangxi University of Traditional Chinese Medicine, 56 Yangmin Road, Nanchang, 330006, China) ,  Yang, Shilin (Jiangxi University of Traditional Chinese Medicine, 56 Yangmin Road, Nanchang, 330006, China)

Abstract AI-Helper 아이콘AI-Helper

AbstractA simple, sensitive and specific liquid chromatography–tandem mass spectrometry method was developed and validated for the determination of Pulsatilla saponin D, a potential antitumor constituent isolated from Pulsatilla chinensis in rat plasma. Rat plasma samples were pretreated by pr...

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참고문헌 (28)

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