$\require{mediawiki-texvc}$

연합인증

연합인증 가입 기관의 연구자들은 소속기관의 인증정보(ID와 암호)를 이용해 다른 대학, 연구기관, 서비스 공급자의 다양한 온라인 자원과 연구 데이터를 이용할 수 있습니다.

이는 여행자가 자국에서 발행 받은 여권으로 세계 각국을 자유롭게 여행할 수 있는 것과 같습니다.

연합인증으로 이용이 가능한 서비스는 NTIS, DataON, Edison, Kafe, Webinar 등이 있습니다.

한번의 인증절차만으로 연합인증 가입 서비스에 추가 로그인 없이 이용이 가능합니다.

다만, 연합인증을 위해서는 최초 1회만 인증 절차가 필요합니다. (회원이 아닐 경우 회원 가입이 필요합니다.)

연합인증 절차는 다음과 같습니다.

최초이용시에는
ScienceON에 로그인 → 연합인증 서비스 접속 → 로그인 (본인 확인 또는 회원가입) → 서비스 이용

그 이후에는
ScienceON 로그인 → 연합인증 서비스 접속 → 서비스 이용

연합인증을 활용하시면 KISTI가 제공하는 다양한 서비스를 편리하게 이용하실 수 있습니다.

Taraxasterol inhibits IL-1β-induced inflammatory response in human osteoarthritic chondrocytes

European journal of pharmacology, v.756, 2015년, pp.38 - 42  

Piao, T. ,  Ma, Z. ,  Li, X. ,  Liu, J.

Abstract AI-Helper 아이콘AI-Helper

Osteoarthritis (OA), a chronic degenerative joint disease, is a leading cause of disability among elderly patients. Taraxasterol, a pentacyclic-triterpene isolated from Taraxacum officinale, has been shown to have anti-inflammatory effects. However, the protective effect of taraxasterol on OA remain...

주제어

참고문헌 (34)

  1. Int. Immunopharmacol. Chen 12 447 2012 10.1016/j.intimp.2011.12.024 Morin inhibits interleukin-1beta-induced nitric oxide and prostaglandin E2 production in human chondrocytes 

  2. Int. Immunopharmacol. Chen 19 174 2014 10.1016/j.intimp.2013.12.007 Astaxanthin reduces matrix metalloproteinase expression in human chondrocytes 

  3. J. Orthop. Res.: Off. Publ. Orthop. Res. Soc. Chen 32 573 2014 10.1002/jor.22577 Honokiol, a low molecular weight natural product, prevents inflammatory response and cartilage matrix degradation in human osteoarthritis chondrocytes 

  4. Osteoarthr. Cartil./OARS Osteoarthr. Res. Soc. Cheng 19 118 2011 10.1016/j.joca.2010.10.019 Selenomethionine inhibits IL-1beta inducible nitric oxide synthase (iNOS) and cyclooxygenase 2 (COX2) expression in primary human chondrocytes 

  5. BMC Complement. Altern. Med. Citalingam 13 213 2013 10.1186/1472-6882-13-213 Effects of Payena dasyphylla (Miq.) on hyaluronidase enzyme activity and metalloproteinases protein expressions in interleukin-1beta stimulated human chondrocytes cells 

  6. J. Med. Food Colle 15 549 2012 10.1089/jmf.2011.0282 Antioxidant properties of Taraxacum officinale leaf extract are involved in the protective effect against hepatoxicity induced by acetaminophen in mice 

  7. Clin. Interv. Aging Imamura 9 939 2014 Concentration of cytokines in patients with osteoarthritis of the knee and fibromyalgia 

  8. In Vitro Cell. Dev. Biol. Anim. Itthiarbha 48 43 2012 10.1007/s11626-011-9475-7 Polyoxypregnane glycoside from Dregea volubilis extract inhibits IL-1beta-induced expression of matrix metalloproteinase via activation of NF-kappaB in human chondrocytes 

  9. Biochem. Pharmacol. Joh 84 331 2012 10.1016/j.bcp.2012.04.020 Echinocystic acid ameliorates lung inflammation in mice and alveolar macrophages by inhibiting the binding of LPS to TLR4 in NF-kappaB and MAPK pathways 

  10. Biomol. Ther. Kang 22 239 2014 10.4062/biomolther.2014.020 Luteolin inhibits the activity, secretion and gene expression of MMP-3 in cultured articular chondrocytes and production of MMP-3 in the rat knee 

  11. Arthritis Res. Ther. Kato 16 R163 2014 10.1186/ar4679 Exosomes from IL-1beta stimulated synovial fibroblasts induce osteoarthritic changes in articular chondrocytes 

  12. J. Immunol. Kimura 178 3316 2007 10.4049/jimmunol.178.5.3316 A critical role for allograft inflammatory factor-1 in the pathogenesis of rheumatoid arthritis 

  13. J. Orthop. Res.: Off. Publ. Orthop. Res. Soc. Klatt 27 65 2009 10.1002/jor.20716 A critical role for collagen II in cartilage matrix degradation: collagen II induces pro-inflammatory cytokines and MMPs in primary human chondrocytes 

  14. Osteoarthr. Cartil. Li 22 481 2014 10.1016/j.joca.2013.12.020 BMP-2 induces ATF4 phosphorylation in chondrocytes through a COX-2/PGE2 dependent signaling pathway 

  15. Int. J. Mol. Sci. Liu 15 6925 2014 10.3390/ijms15046925 Protective effect of resveratrol against IL-1beta-induced inflammatory response on human osteoarthritic chondrocytes partly via the TLR4/MyD88/NF-kappaB signaling pathway: an “in vitro study” 

  16. J. Ethnopharmacol. Liu 130 392 2010 10.1016/j.jep.2010.05.029 Taraxacum officinale protects against lipopolysaccharide-induced acute lung injury in mice 

  17. Int. J. Mol. Med. Moon 30 1451 2012 10.3892/ijmm.2012.1135 Sphingosine-1-phosphate inhibits interleukin-1beta-induced inflammation in human articular chondrocytes 

  18. Am. J. Geriatr. Pharmacother. O’Neil 10 331 2012 10.1016/j.amjopharm.2012.09.004 Adverse effects of analgesics commonly used by older adults with osteoarthritis: focus on non-opioid and opioid analgesics 

  19. Neoplasma Ovesna 51 407 2004 Taraxasterol and beta-sitosterol: new naturally compounds with chemoprotective/chemopreventive effects 

  20. Arthritis Res. Ther. Reisch 10 R60 2008 10.1186/ar2431 DREAM is reduced in synovial fibroblasts of patients with chronic arthritic pain: is it a suitable target for peripheral pain management? 

  21. Phys. Ther. Riddle 94 490 2014 10.2522/ptj.20130331 Knee pain during daily tasks, knee osteoarthritis severity, and widespread pain 

  22. Int. Immunopharmacol. San 19 342 2014 10.1016/j.intimp.2014.01.031 Protective effect of taraxasterol on acute lung injury induced by lipopolysaccharide in mice 

  23. Int. Immunopharmacol. Stratz 22 160 2014 10.1016/j.intimp.2014.06.003 Anti-inflammatory effects of 5-HT3 receptor antagonists in interleukin-1beta stimulated primary human chondrocytes 

  24. J. Vet. Med. Sci./Jpn. Soc. Vet. Sci. Sunaga 74 707 2012 10.1292/jvms.11-0511 Inhibitory effects of pentosan polysulfate sodium on MAP-kinase pathway and NF-kappaB nuclear translocation in canine chondrocytes in vitro 

  25. Mediat. Inflamm. Wojdasiewicz 2014 561459 2014 10.1155/2014/561459 The role of inflammatory and anti-inflammatory cytokines in the pathogenesis of osteoarthritis 

  26. J. Ethnopharmacol. Xiong 155 753 2014 10.1016/j.jep.2014.06.023 Effects of taraxasterol on iNOS and COX-2 expression in LPS-induced RAW 264.7 macrophages 

  27. Exp. Ther. Med. Xu 8 1065 2014 10.3892/etm.2014.1862 Sanmiao formula inhibits chondrocyte apoptosis and cartilage matrix degradation in a rat model of osteoarthritis 

  28. FEBS Lett. Yang 588 2344 2014 10.1016/j.febslet.2014.05.033 Effect of microRNA-145 on IL-1beta-induced cartilage degradation in human chondrocytes 

  29. Biochem. Pharmacol. Yang 85 1124 2013 10.1016/j.bcp.2013.01.020 Gastrodin attenuation of the inflammatory response in H9c2 cardiomyocytes involves inhibition of NF-kappaB and MAPKs activation via the phosphatidylinositol 3-kinase signaling 

  30. Int. Orthop. Ying 38 1519 2014 10.1007/s00264-013-2219-4 Cordycepin prevented IL-beta-induced expression of inflammatory mediators in human osteoarthritis chondrocytes 

  31. Immunopharmacol. Immunotoxicol. Zhang 36 11 2014 10.3109/08923973.2013.861482 Protective effect of taraxasterol against LPS-induced endotoxic shock by modulating inflammatory responses in mice 

  32. J. Ethnopharmacol. Zhang 141 206 2012 10.1016/j.jep.2012.02.020 Effects of taraxasterol on inflammatory responses in lipopolysaccharide-induced RAW 264.7 macrophages 

  33. Drug Dev. Res. Zhang 75 195 2014 beta-Ecdysterone suppresses interleukin-1beta-induced apoptosis and inflammation in rat chondrocytes via inhibition of NF-kappaB signaling pathway 

  34. J. Cell. Mol. Med. Zhao 18 283 2014 10.1111/jcmm.12186 Berberine ameliorates cartilage degeneration in interleukin-1 beta-stimulated rat chondrocytes and in a rat model of osteoarthritis via Akt signalling 

관련 콘텐츠

이 논문과 함께 이용한 콘텐츠

저작권 관리 안내
섹션별 컨텐츠 바로가기

AI-Helper ※ AI-Helper는 오픈소스 모델을 사용합니다.

AI-Helper 아이콘
AI-Helper
안녕하세요, AI-Helper입니다. 좌측 "선택된 텍스트"에서 텍스트를 선택하여 요약, 번역, 용어설명을 실행하세요.
※ AI-Helper는 부적절한 답변을 할 수 있습니다.

선택된 텍스트

맨위로