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NTIS 바로가기PloS one, v.10 no.3, 2015년, pp.e0119452 -
Graham, Stewart F. (Advanced Asset Technology Centre, Institute for Global Food Security, Queen’s University Belfast, Stranmillis Road, Belfast, BT9 5AG, United Kingdom) , Chevallier, Olivier P. (Advanced Asset Technology Centre, Institute for Global Food Security, Queen’s University Belfast, Stranmillis Road, Belfast, BT9 5AG, United Kingdom) , Elliott, Christopher T. (Advanced Asset Technology Centre, Institute for Global Food Security, Queen’s University Belfast, Stranmillis Road, Belfast, BT9 5AG, United Kingdom) , Hölscher, Christian (Division of Biomedical Sciences and Life Sciences, Lancaster University, Lancaster, LA1 4YG, United Kingdom) , Johnston, Janet (Ageing Group, Centre for Public Health, Queen's University Belfast, Belfast, BT12 6BA, United Kingdom) , McGuinness, Bernadette (Ageing Group, Centre for Public Health, Queen's University Belfast, Belfast, BT12 6BA, United Kingdom) , Kehoe, Patrick G. (Dementia Research Group, Institute of Clinical Neurosciences, School of Clinical Sciences, University of Bristol, Frenchay Hospital, Bristol, BS16 1LE, United Kingdom) , Passmore, Anthony Peter (Ageing Group, Centre for Public Health, Queen's Univer) , Green, Brian D.
This study combined high resolution mass spectrometry (HRMS), advanced chemometrics and pathway enrichment analysis to analyse the blood metabolome of patients attending the memory clinic: cases of mild cognitive impairment (MCI; n = 16), cases of MCI who upon subsequent follow-up developed Alzheime...
1 Monge-Argiles JA , Munoz-Ruiz C , Pampliega-Perez A , Gomez-Lopez MJ , Sanchez-Paya J , Rodriguez Borja E , et al Biomarkers of Alzheimer's disease in the cerebrospinal fluid of spanish patients with mild cognitive impairment . Neurochem Res 2011 ; 36 : 986 – 93 . 10.1007/s11064-011-0438-x 21399907
2 Knight WD , Okello AA , Ryan NS , Turkheimer FE , Rodriguez Martinez de Llano S , Edison P , et al Carbon-11-pittsburgh compound B positron emission tomography imaging of amyloid deposition in presenilin 1 mutation carriers . Brain 2011 ; 134 : 293 – 300 . 10.1093/brain/awq310 21084313
3 Dubois B , Feldman HH , Jacova C , Dekosky ST , Barberger-Gateau P , Cummings J , et al Research criteria for the diagnosis of alzheimer's disease: Revising the NINCDS-ADRDA criteria . Lancet Neurol 2007 ; 6 : 734 – 46 . 17616482
4 Petersen RC . Mild cognitive impairment as a diagnostic entity . J Intern Med 2004 ; 256 : 183 – 94 . 15324362
5 Petersen RC , Smith GE , Waring SC , Ivnik RJ , Tangalos EG , Kokmen E . Mild cognitive impairment: Clinical characterization and outcome . Arch Neurol 1999 ; 56 : 303 – 8 . 10190820
6 Lopez OL , Kuller LH , Becker JT , Dulberg C , Sweet RA , Gach HM , et al Incidence of dementia in mild cognitive impairment in the cardiovascular health study cognition study . Arch Neurol 2007 ; 64 : 416 – 20 . 17353386
7 Mitchell AJ , Shiri-Feshki M . Rate of progression of mild cognitive impairment to dementia—meta-analysis of 41 robust inception cohort studies . Acta Psychiatr Scand 2009 ; 119 : 252 – 65 . 10.1111/j.1600-0447.2008.01326.x 19236314
8 Beckonert O , Keun HC , Ebbels TM , Bundy J , Holmes E , Lindon JC , et al Metabolic profiling, metabolomic and metabonomic procedures for NMR spectroscopy of urine, plasma, serum and tissue extracts . Nat Protoc 2007 ; 2 : 2692 – 703 . 18007604
9 Kaddurah-Daouk R , Zhu H , Sharma S , Bogdanov M , Rozen SG , Matson W , et al Alterations in metabolic pathways and networks in alzheimer's disease . Transl Psychiatry 2013 ; 3 : e244 10.1038/tp.2013.18 23571809
10 Graham SF , Holscher C , McClean P , Elliott C , Green B . Brain tissue and plasma used to metabolically phenotype alzheimer’s disease in APP/PS1 mice . Metabolomics 2013 ; 9 : 974 – 983 .
11 Ibanez C , Simo C , Barupal DK , Fiehn O , Kivipelto M , Cedazo-Minguez A , et al A new metabolomic workflow for early detection of alzheimer's disease . J Chromatogr A 2013 ; 1302 : 65 – 71 . 10.1016/j.chroma.2013.06.005 23827464
12 Folstein MF , Folstein SE , McHugh PR . "Mini-mental state". A practical method for grading the cognitive state of patients for the clinician . J Psychiatr Res 1975 ; 12 : 189 – 98 . 1202204
13 Mioshi E , Dawson K , Mitchell J , Arnold R , Hodges JR . The addenbrooke's cognitive examination revised (ACE-R): A brief cognitive test battery for dementia screening . Int J Geriatr Psychiatry 2006 ; 21 : 1078 – 85 . 16977673
14 Winblad B , Palmer K , Kivipelto M , Jelic V , Fratiglioni L , Wahlund LO , et al Mild cognitive impairment—beyond controversies, towards a consensus: Report of the international working group on mild cognitive impairment . J Intern Med 2004 ; 256 : 240 – 6 . 15324367
15 McKhann G , Drachman D , Folstein M , Katzman R , Price D , Stadlan EM . Clinical diagnosis of alzheimer's disease: Report of the NINCDS-ADRDA work group under the auspices of department of health and human services task force on alzheimer's disease . Neurology 1984 ; 34 : 939 – 44 . 6610841
16 Brandt J , Aretouli E , Neijstrom E , Samek J , Manning K , Albert MS , et al Selectivity of executive function deficits in mild cognitive impairment . Neuropsychology 2009 ; 23 : 607 – 18 . 10.1037/a0015851 19702414
17 Nordlund A , Rolstad S , Klang O , Edman A , Hansen S , Wallin A . Two-year outcome of MCI subtypes and aetiologies in the goteborg MCI study . J Neurol Neurosurg Psychiatry 2010 ; 81 : 541 – 6 . 10.1136/jnnp.2008.171066 19965857
18 Summers MJ , Saunders NL . Neuropsychological measures predict decline to alzheimer's dementia from mild cognitive impairment . Neuropsychology 2012 ; 26 : 498 – 508 . 10.1037/a0028576 22612573
19 Graham SF , Chevallier OP , Roberts D , Holscher C , Elliott CT , Green BD . An investigation of the human brain metabolome to identify potential markers for early diagnosis and therapeutic targets of alzheimer’s disease . Analytical Chemistry 2012 ; 85 : 1803 – 11 .
20 Zhang A , Zhou X , Zhao H , Guan Y , Zhou S , et al ( 2014 ) Rapidly improved determination of metabolites from biological data sets using the high-efficient TransOmics tool . Mol Biosyst 10 : 2160 – 2165 . 10.1039/c4mb00222a 24889752
21 Want EJ , Wilson ID , Gika H , Theodoridis G , Plumb RS , Shockcor J , et al Global metabolic profiling procedures for urine using UPLC-MS . Nat Protoc 2010 ; 5 : 1005 – 18 . 10.1038/nprot.2010.50 20448546
22 Tsang TM , Haselden JN , Holmes E . Metabonomic characterization of the 3-nitropropionic acid rat model of huntington's disease . Neurochem Res 2009 ; 34 : 1261 – 71 . 10.1007/s11064-008-9904-5 19148750
23 Oresic M , Hyotylainen T , Herukka S , Sysi-Aho M , Mattila I , Seppanan-Laakso T , et al Metabolome in progression to alzheimer’s disease . Translational Psych . 2011 , 1 : e57
24 Trushina E , Dutta T , Persson XM , Mielke MM , Petersen RC . Identification of altered metabolic pathways in plasma and CSF in mild cognitive impairment and alzheimer's disease using metabolomics . PLoS One 2013 ; 8 : e63644 10.1371/journal.pone.0063644 23700429
25 Motsinger-Reif A , Zhu H , Kling M , Matson W , Sharma S , Fiehn O , et al Comparing metabolomic and pathologic biomarkers alone and in combination for discriminating alzheimer's disease from normal cognitive aging . Acta Neuropathologica Communications 2013 ; 1 : 28 10.1186/2051-5960-1-28 24252434
26 Vural H , Sirin B , Yilmaz N , Eren I , Delibas N . The role of arginine-nitric oxide pathway in patients with alzheimer disease . Biol Trace Elem Res 2009 ; 129 : 58 – 64 . 10.1007/s12011-008-8291-8 19099206
27 Becker-Catania SG , Gregory TL , Yang Y , Gau CL , de Vellis J , Cederbaum SD , et al Loss of arginase I results in increased proliferation of neural stem cells . J Neurosci Res 2006 ; 84 : 735 – 46 . 16773651
28 Maxwell AJ , Anderson B , Zapien MP , Cooke JP . Endothelial dysfunction in hypercholesterolemia is reversed by a nutritional product designed to enhance nitric oxide activity . Cardiovasc Drugs Ther 2000 ; 14 : 309 – 16 . 10935153
29 Esch F , Lin KI , Hills A , Zaman K , Baraban JM , Chatterjee S , et al Purification of a multipotent antideath activity from bovine liver and its identification as arginase: Nitric oxide-independent inhibition of neuronal apoptosis . J Neurosci 1998 ; 18 : 4083 – 95 . 9592089
30 Wallace HM , Fraser AV , Hughes A . A perspective of polyamine metabolism . Biochem J 2003 ; 376 : 1 – 14 . 13678416
31 Inoue K , Tsutsui H , Akatsu H , Hashizume Y , Matsukawa N , Yamamoto T , et al Metabolic profiling of Alzheimer's disease brains . Sci Rep 2013 ; 3 : 2364 10.1038/srep02364 23917584
32 Yatin SM , Varadarajan S , Link CD , Butterfield DA . In vitro and in vivo oxidative stress associated with alzheimer's amyloid beta-peptide (1–42) . Neurobiol Aging 1999 ; 20 : 325 , 30 ; discussion 339–42. 10588580
33 Yatin SM , Yatin M , Varadarajan S , Ain KB , Butterfield DA . Role of spermine in amyloid beta-peptide-associated free radical-induced neurotoxicity . J Neurosci Res 2001 ; 63 : 395 – 401 . 11223914
34 Makitie LT , Kanerva K , Polvikoski T , Paetau A , Andersson LC . Brain neurons express ornithine decarboxylase-activating antizyme inhibitor 2 with accumulation in alzheimer's disease . Brain Pathol 2010 ; 20 : 571 – 80 . 10.1111/j.1750-3639.2009.00334.x 19832840
35 Rossor MN , Garrett NJ , Johnson AL , Mountjoy CQ , Roth M , Iversen LL . A post-mortem study of the cholinergic and GABA systems in senile dementia . Brain 1982 ; 105 : 313 – 30 . 7082992
36 Salek RM , Xia J , Innes A , Sweatman BC , Adalbert R , Randle S , et al A metabolomic study of the CRND8 transgenic mouse model of alzheimer's disease . Neurochem Int 2010 ; 56 : 937 – 47 . 10.1016/j.neuint.2010.04.001 20398713
37 Lalande J , Halley H , Balayssac S , Gilard V , Dejean S , Martino R , et al 1H NMR metabolomic signatures in five brain regions of the AbetaPPswe Tg2576 mouse model of alzheimer's disease at four ages . J Alzheimers Dis 2014 ; 39 : 121 – 43 . 10.3233/JAD-130023 24145382
38 Lowe SL , Francis PT , Procter AW , Palmer AM , Davison AN , Bowden DM . Gamma-Amminobutryic Acid Concentration in Brain Tissue at Two Stages of Alzheimer's disease . Brain 1988 ; 111 : 785 – 99 . 3401683
39 Gamba P , Testa G , Sottero B , Gargiulo S , Poli G , Leonarduzzi G . The link between altered cholesterol metabolism and alzheimer's disease . Ann N Y Acad Sci 2012 ; 1259 : 54 – 64 . 10.1111/j.1749-6632.2012.06513.x 22758637
40 Jones L , Holmans PA , Hamshere ML , Harold D , Moskvina V , Ivanov D , et al Genetic evidence implicates the immune system and cholesterol metabolism in the aetiology of alzheimer's disease . PLoS One 2010 ; 5 : e13950 10.1371/journal.pone.0013950 21085570
41 Kloppenborg RP , van den Berg E , Kappelle LJ , Biessels GJ . Diabetes and other vascular risk factors for dementia: Which factor matters most? A systematic review . Eur J Pharmacol 2008 ; 585 : 97 – 108 . 10.1016/j.ejphar.2008.02.049 18395201
42 Li L , Holscher C . Common pathological processes in alzheimer disease and type 2 diabetes: A review . Brain Res Rev 2007 ; 56 : 384 – 402 . 17920690
43 Crane PK , Walker R , Hubbard RA , Li G , Nathan DM , Zheng H , et al Glucose levels and risk of dementia . N Engl J Med 2013 ; 369 : 540 – 8 . 10.1056/NEJMoa1215740 23924004
44 McGeer PL , Schulzer M , McGeer EG . Arthritis and anti-inflammatory agents as possible protective factors for alzheimer's disease: A review of 17 epidemiologic studies . Neurology 1996 ; 47 : 425 – 32 . 8757015
45 Leoutsakos JM , Muthen BO , Breitner JC , Lyketsos CG , ADAPT Research Team . Effects of non-steroidal anti-inflammatory drug treatments on cognitive decline vary by phase of pre-clinical alzheimer disease: Findings from the randomized controlled alzheimer's disease anti-inflammatory prevention trial . Int J Geriatr Psychiatry 2012 ; 27 : 364 – 74 . 10.1002/gps.2723 21560159
46 Xiang Z , Ho L , Yemul S , Zhao Z , Qing W , Pompl P , et al Cyclooxygenase-2 promotes amyloid plaque deposition in a mouse model of alzheimer's disease neuropathology . Gene Expr 2002 ; 10 : 271 – 8 . 12450219
47 Melnikova T , Savonenko A , Wang Q , Liang X , Hand T , Wu L , et al Cycloxygenase-2 activity promotes cognitive deficits but not increased amyloid burden in a model of Alzheimer's disease in a sex-dimorphic pattern . Neuroscience 2006 ; 141 : 1149 – 62 . 16753269
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