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NTIS 바로가기BioMed research international, v.2014, 2014년, pp.805926 -
Sun, Hongwei (Department of Surgery, First Affiliated Hospital of Wenzhou Medical University, Wenzhou 325000, China) , Lv, Chongqing (Department of Surgery, First Affiliated Hospital of Wenzhou Medical University, Wenzhou 325000, China) , Yang, Longlong (Department of Surgery, First Affiliated Hospital of Wenzhou Medical University, Wenzhou 325000, China) , Wang, Yingxiu (Department of Surgery, First Affiliated Hospital of Wenzhou Medical University, Wenzhou 325000, China) , Zhang, Qingshun (Department of Surgery, First Affiliated Hospital of Wenzhou Medical University, Wenzhou 325000, China) , Yu, Suhui (Department of Surgery, First Affiliated Hospital of Wenzhou Medical University, Wenzhou 325000, China) , Kong, Hongru (Department of Surgery, First Affiliated Hospital of Wenzhou Medical University, Wenzhou 325000, China) , Wang, Meng (Department of Surgery, First Affiliated Hospital of Wenzhou Medical University, Wenzhou 325000, China) , Xie, Jianming (Department of Surgery, First Affiliated Hospital of Wenzhou Medical University, Wenzhou 325000, China) , Zhang, Chunwu (Wenzhou Key Laboratory of Surgery, Department of Surgery, First) , Zhou, Mengtao
Steroid alkaloids have been suggested as potential anticancer compounds. However, the underlying mechanisms of how steroid alkaloids inhibit the tumor growth are largely unknown. Here, we reported that solanine, a substance of steroid alkaloids, has a positive effect on the inhibition of pancreatic ...
1 Lam ET Bracci PM Holly EA Mitochondrial DNA sequence variation and risk of pancreatic cancer Cancer Research 2012 72 3 686 695 2-s2.0-84856521481 22174369
2 Howard TJ Pancreatic adenocarcinoma Current Problems in Cancer 1996 20 5 281 328 8902402
3 Jemal A Siegel R Xu J Ward E Cancer statistics, 2010 CA: Cancer Journal for Clinicians 2010 60 5 277 300 2-s2.0-77955635233
5 Werner J Büchler MW Management of pancreatic cancer: recent advances Deutsche Medizinische Wochenschrift 2011 136 36 1807 1810 2-s2.0-80052314284 21882139
6 Friedman M Lee KR Kim HJ Lee IS Kozukue N Anticarcinogenic effects of glycoalkaloids from potatoes against human cervical, liver, lymphoma, and stomach cancer cells Journal of Agricultural and Food Chemistry 2005 53 15 6162 6169 2-s2.0-23744506485 16029012
7 Kuo CI Chao CH Lu MK Effects of auxins on the production of steroidal alkaloids in rapidly proliferating tissue and cell cultures of Solanum lyratum Phytochemical Analysis 2012 23 4 400 404 22009634
8 Son YO Kim J Lim JC Chung Y Chung GH Lee JC Ripe fruits of Solanum nigrum L. inhibits cell growth and induces apoptosis in MCF-7 cells Food and Chemical Toxicology 2003 41 10 1421 1428 2-s2.0-0141767071 12909277
9 Reddivari L Vanamala J Safe SH Miller JC Jr. The bioactive compounds α -chaconine and gallic acid in potato extracts decrease survival and induce apoptosis in LNCaP and PC3 prostate cancer cells Nutrition and Cancer 2010 62 5 601 610 2-s2.0-77954020000 20574921
10 Patil BC Sharma RP Salunkhe DK Salunkhe K Evaluation of solanine toxicity Food and Cosmetics Toxicology 1972 10 3 395 398 2-s2.0-0015357114 5045682
11 Yang SA Paek SH Kozukue N Lee KR Kim JA α -Chaconine, a potato glycoalkaloid, induces apoptosis of HT-29 human colon cancer cells through caspase-3 activation and inhibition of ERK 1/2 phosphorylation Food and Chemical Toxicology 2006 44 6 839 846 2-s2.0-33645945275 16387404
12 Lu MK Shih YW Chien TTC Fang LH Huang HC Chen PS α -Solanine inhibits human melanoma cell migration and invasion by reducing matrix metalloproteinase-2/9 activities Biological and Pharmaceutical Bulletin 2010 33 10 1685 1691 2-s2.0-77958008016 20930376
13 Choi SH Lee SH Kim HJ Changes in free amino acid, phenolic, chlorophyll, carotenoid, and glycoalkaloid contents in tomatoes during 11 stages of growth and inhibition of cervical and lung human cancer cells by green tomato extracts Journal of Agricultural and Food Chemistry 2010 58 13 7547 7556 2-s2.0-77954560979 20560602
14 Gao SY Wang QJ Ji YB Effect of solanine on the membrane potential of mitochondria in HepG2 cells and [Ca 2+ ] i in the cells World Journal of Gastroenterology 2006 12 21 3359 3367 2-s2.0-33745320827 16733852
15 Ji YB Gao SY Ji CF Zou X Induction of apoptosis in HepG2 cells by solanine and Bcl-2 protein Journal of Ethnopharmacology 2008 115 2 194 202 2-s2.0-37249089342 18022776
16 Zhang J Shi GW Inhibitory effect of solanine on prostate cancer cell line PC-3 in vitro National Journal of Andrology 2011 17 3 284 287 2-s2.0-82255191366 21485553
17 Muñoz-Pinedo C Signaling pathways that regulate life and cell death: evolution of apoptosis in the context of self-defense Advances in Experimental Medicine and Biology 2012 738 124 143 2-s2.0-84859871133 22399377
18 Schultz DR Harrington WJ Jr. Apoptosis: programmed cell death at a molecular level Seminars in Arthritis and Rheumatism 2003 32 6 345 369 2-s2.0-0037633932 12833244
19 Shimizu S Narita M Tsujimoto Y Bcl-2 family proteins regulate the release of apoptogenic cytochrome c by the mitochondrial channel VDAC Nature 1999 399 6735 483 487 2-s2.0-0033519705 10365962
20 Spierings D McStay G Saleh M Connected to death: the (unexpurgated) mitochondrial pathway of apoptosis Science 2005 310 5745 66 67 2-s2.0-26444489119 16210526
21 Antonsson B Mitochondria and the Bcl-2 proteins in apoptosis signaling pathways Molecular and Cellular Biochemistry 2004 256-257 1-2 141 155 2-s2.0-0842280583 14977177
22 Green DR Kroemer G The pathophysiology of mitochondrial cell death Science 2004 305 5684 626 629 2-s2.0-3442886811 15286356
23 Filomeni G Cardaci S Da Costa Ferreira AM Rotilio G Ciriolo MR Metabolic oxidative stress elicited by the copper(II) complex [Cu(isaepy)2] triggers apoptosis in SH-SY5Y cells through the induction of the AMP-activated protein kinase/p38MAPK/p53 signalling axis: evidence for a combined use with 3-bromopyruvate in neuroblastoma treatment Biochemical Journal 2011 437 3 443 453 2-s2.0-79960263592 21548882
24 Hemann MT Lowe SW The p53-Bcl-2 connection Cell Death and Differentiation 2006 13 8 1256 1259 2-s2.0-33745961862 16710363
25 Wu KC Yang ST Hsia TC Suppression of cell invasion and migration by propofol are involved in down-regulating matrix metalloproteinase-2 and p38 MAPK signaling in A549 human lung adenocarcinoma epithelial cells Anticancer Research 2012 32 11 4833 4842 23155249
26 Kim YH Kwon HJ Kim DS Matrix metalloproteinase 9 (MMP-9)-dependent processing of betaig-h3 protein regulates cell migration, invasion, and adhesion The Journal of Biological Chemistry 2012 287 46 38957 38969 23019342
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