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Novel FLG null mutations in Korean patients with atopic dermatitis and comparison of the mutational spectra in Asian populations

The Journal of dermatology, v.42 no.9, 2015년, pp.867 - 873  

Park, Joonhong (Department of Laboratory Medicine, College of Medicine, The Catholic University of Korea, Seoul, Korea) ,  Jekarl, Dong Wook (Department of Laboratory Medicine, College of Medicine, The Catholic University of Korea, Seoul, Korea) ,  Kim, Yonggoo (Department of Laboratory Medicine, College of Medicine, The Catholic University of Korea, Seoul, Korea) ,  Kim, Jiyeon (Catholic Genetic Laboratory Center, College of Medicine, The Catholic University of Korea, Seoul, Korea) ,  Kim, Myungshin (Department of Laboratory Medicine, College of Medicine, The Catholic University of Korea, Seoul, Korea) ,  Park, Young Min (Department of Dermatology, College of Medicine, The Catholic University of Korea, Seoul, Korea)

Abstract AI-Helper 아이콘AI-Helper

AbstractFilaggrin is essential for the development of the skin barrier. Mutations in the gene encoding filaggrin have been identified as major predisposing factors for atopic disorders. Molecular analysis of the FLG gene in this study showed nine null and one unclassified mutation in 13 of 81 Korean...

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참고문헌 (45)

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