참고문헌 (78)

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31. 31 Narsinghani T Sharma R Lead Optimization on conventional NSAIDs: An approach to reduce gastrointestinal toxicity Chem Biol Drug Des 2014 84 1 23 24460671 

32. 32 Mas R D-002: A product obtained from beeswax Drugs Future 2001 26 731 44 

33. 33 Carbajal D Molina V Valdés S Arruzazabala ML Mas R Anti-ulcer activity of higher primary alcohols of beeswax J Pharm Phamacol 1995 47 731 3 

34. 34 Carbajal D Molina V Valdés S Arruzazabala ML Rodeiro I Mas R Possible cytoprotective mechanism in rats of D-002 an antiulcerogenic product isolated from beeswax J Pharm Pharmacol 1996 48 858 60 8887738 

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35. 35 Carbajal D Molina V Noa M Valdes S Arruzazabala ML Aguiar A Effects of D-002 on gastric mucus composition in ethanol-induced ulcer Pharmacol Res 2000 42 329 32 10987992 

36. 36 Molina V Valdés S Carbajal D Arruzazabala L Menéndez R Mas R Antioxidant effects of D-002 on gastric mucosa of rats with injury induced experimentally J Med Food 2001 4 79 84 12639416 

37. 37 Pérez Y Oyárzabal A Mas R Molina V Jiménez S Protective effect of D-002, a mixture of beeswax alcohols, against indomethacin-induced gastric ulcers and mechanism of action J Nat Med 2013 67 182 9 22576364 

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38. 38 Valle M Noa M Mendoza S Oyarzábal A Molina V Mendoza N Effects of D-002 on aspirin-induced ulcers and neutrophil infiltration on the gastric mucosa Revista Cubana de Farmacia (Cuban J Pharm) 2012 46 249 58 

39. 39 Menéndez R Amor AM González RM Jiménez S Mas R Inhibition of rat microsomal lipid peroxidation by the oral administration of D-002 Braz J Med Biol Res 2000 33 85 90 10625879 

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40. 40 Pérez Y González R Amor AM Jiménez S Menéndez R D-002 on antioxidant enzymes in liver and brain of rats Rev CENIC Cien Biol 2002 33 3 5 

41. 41 Menéndez R Mas R Amor AM Perez Y González RM Fernández JC Antioxidant effects of D-002 on the in vitro susceptibility in healthy volunteers Arch Med Res 2001 32 436 41 11578760 

42. 42 Menéndez R Mas R Illnait J Pérez J Amor AM Fernández JC Effects of D-002 on lipid peroxidation in older subjects J Med Food 2001 4 71 7 12639415 

43. 43 López E Illnait J Molina V Oyarzábal A Fernández L Pérez Y Effects of D-002 (beeswax alcohols) on lipid peroxidation in middle-aged and older subjects Lat Am J Pharm 2008 27 695 703 

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44. 44 Rodriguez I Illnait J Fernandez L Oyarzábal A Fernández L Fernández JC Comparative antioxidant effects of beeswax alcohols and grape seed extract in healthy persons Lat Am J Pharm 2010 29 255 62 

45. 45 Carbajal D Molina V Noa M Ravelo Y Mas R Valle M Comparative effects of D-002 (beeswax alcohols), ranitidine and omeprazole on acetic acid-induced ulcer Int J Pharmacy Pharm Sci 2013 5 91 5 

46. 46 Carbajal D Molina V Arruzazabala ML Mas R D-002 (Abexol) sobre la ulcera duodenal inducida por cisteamina Rev CENIC Cien Biol 2005 36 167 9 

47. 47 Zamora Z Molina V Mas R Ravelo Y Perez Y Oyarzabal A Protective effects of D-002 on experimentally induced gastroesophageal reflux in rats World J Gastroenterol 2014 20 2085 90 24587681 

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48. 48 Rodriguez I Illnait J Fernandez L Mas R Fernandez L Fernández JC Effects of Abexol® (beeswax alcohols) on gastrointestinal symptoms of middle-aged and older subjects Rev CENIC Cien Biol 2009 40 147 54 

49. 49 Fernández JC Rodríguez I Illnait J Fernández L Mas R Pérez Y Effects of Abexol® (beeswax alcohols) in patients with gastric symptoms Revista CENIC Cien Biol 2012 43 9 16 

50. 50 Illnait J Terry H Mas R Fernandez L Carbajal D Effects of D-002, a product isolated from beeswax, on gastric symptoms of patients with osteoarthritis treated with piroxicam: A pilot study J Med Food 2005 8 63 8 15857212 

51. 51 Illnait J Rodriguez I Molina V Mendoza S Mas R Fernández L Effects of D-002 (beeswax Alcohols) on gastrointestinal symptoms and oxidative markers in middle-aged and older subjects Lat Am J Pharm 2013 32 166 74 

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52. 52 Fernández L Terry H Quiñones AM Diaz B Hernández ML Illnait J Effects of Abexol in middle-aged and older subjects: an open follow-up Rev CENIC Cien Biol 2008 39 3 8 

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54. 54 Di Gennaro A Haeggström JZ Targeting leukotriene B4 in inflammation Expert Opin Ther Targets 2014 18 79 93 24090264 

55. 55 Warren RP Burger RA Sidwell RW Clark LL Effect of triacontanol on numbers and functions of cells involved in inflammatory responses Proc Soc Exp Biol Med 1992 200 349 52 1615010 

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56. 56 McBride PT Clark L Krueger GG Evaluation of triacontanol-containing compounds as antiinflammatory agents using guinea pig models J Invest Dermatol 1987 89 380 3 3668280 

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57. 57 Perez Y Oyarzabal A Molina V Mas R Jiménez S Molina V Effect of D-002 on 5-lipooxygenase activity in vitro Rev Cubana Farm 2012 46 259 66 

58. 58 Pérez Y Oyarzábal A Ravelo Y Mas R Jiménez S Molina V Inhibition of cyclooxygenase and 5-lipooxygenase enzymes by D-002 (beeswax alcohols) Top Curr Nutraceutical Res 2014 12 13 8 

59. 59 Carbajal D Ravelo Y Molina V Mas R Arruzazabala ML Effect of D-002 on models of acute inflammation Int J Pharm Sci Rev Res 2013 21 62 7 

60. 60 Ravelo Y Molina V Carbajal D Arruzazabala ML Mas R Oyarzabal A Effects of single oral and topical administration of D-002 (beeswax alcohols) on xylene induced ear edema in mice Lat Am J Pharm 2010 29 1451 4 

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61. 61 Ravelo Y Molina V Oyarzábal A Pérez Y Noa M Mas R Effects of D-002 on pleural exudates volume and lung injury in rats with carragenan induced pleurisy Int J Pharm Sci Rev Res 2014 [In Press] 

62. 62 Ravelo Y Molina V Pérez Y Oyarzábal A Jiménez S Mas R et al. Anti-oedema effects of D-002 and Lyprinol on the carrageenan-induced pleurisy in rats Int J Pharm Sci Rev Res 2013 23 24 8 

63. 63 Kolaczkowska E Kubes P Neutrophil recruitment and function in health and inflammation Nat Rev Immunol 2013 13 159 75 23435331 

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64. 64 Ravelo Y Molina V Carbajal D Fernández L Fernández J Arruzazabala ML Evaluation of antiinflammatory and antinociceptive effects of D-002 (beeswax alcohols) J Nat Med 2010 65 330 5 21258868 

65. 65 Carbajal D Molina V Ravelo Y Mas R Effects of D-002, a mixture of beeswax alcohols, on the acetic acid induced writhing test in mice: A comparison with naproxen, aspirin and paracetamol Rev CENIC Cien Biol 2013 44 1 7 

66. 66 Molina V Ravelo Y Mas R Carbajal D Arruzazabala ML Anti-inflammatory and gastric effects of D-002, aspirin and naproxen and their combined therapy in rats with cotton pellet-induced granuloma Lat Am J Pharm 2011 30 1709 13 

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67. 67 Mendoza S Noa M Valle M Mendoza N Mas R Effects of D-002 on formaldehyde-induced osteoarthritis in rats IOSR J Pharm 2013 3 9 12 

68. 68 Mendoza S Noa M Valle M Mendoza N Mas R Ameliorating effects of D-002, a mixture of beeswax alcohols, on monosodium iodoacetate-induced osteoarthritis in rats Int J Pharm Sci Rev Res 2013 19 10 5 

69. 69 Rodríguez I Mendoza S Illnait J Mas R Fernández Fernández L Effects of D-002, a mixture of beeswax alcohols, on osteoarthritis symptoms: A randomized placebo-controlled study IOSR J Pharm 2012 2 1 9 

70. 70 Puente R Illnait J Mas R Carbajal D Mendoza S Fernández JC Evaluation of the effect of D-002, a mixture of beeswax alcohols, on osteoarthritis symptoms Korean J Intern Med 2014 29 191 202 24648802 

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71. 71 Rodeiro I Aleman C Mas R Noa M Briñis F Hernández C Toxicología aguda oral del D-002 en ratas Sprague Dawley Rev CENIC Cien Biol 1995 26 34 6 

72. 72 Rodeiro I Alemán C Noa M Menendez R Mas R Hernandez C Preclinical oral toxicology in rats of D-002 a natural drug with antiulcer effects Drug Chem Tox 1998 21 151 62 

73. 73 Rodeiro I Aleman C Noa M Rendon A Mas R Fernández SI Oral toxicological studies of D-002 in mice Rev CENIC Cien Biol 1999 30 73 6 

74. 74 Alemán CL Rodeiro I Noa M Menéndez R Gámez R Hernández C One-year dog toxicity study of D-002, a mixture of aliphatic alcohols J Appl Toxicol 2001 21 179 84 11404829 

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75. 75 Rodeiro I Gámez R Acosta P Fernández I Mas R Alemán C Estudio genotoxico del D-002, un producto con actividad antiulcerosa Rev Esp Tox 1998 15 117 21 

76. 76 Gámez R Gutiérrez A Arencibia D Curveco D García H In vitro genotoxic potential of D-002 on the blood lymphocytes chromosomal aberration test Lat Am J Pharm 2010 29 459 62 

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77. 77 Gámez R Fernández I Acosta PC Alemán C Rodeiro I Evaluacion mutagénica del D-002 en el ensayo de micronúcleos en médula ósea en ratas Sprague Dawley de ambos sexos Rev CENIC Cien Biol 1999 30 70 2 

78. 78 Rodríguez MD Gámez R Sánchez M García H Developmental toxicity of D-002 a mixture of aliphatic primary alcohols in rats and rabbits J Appl Toxicol 1998 18 313 6 9804430 

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