참고문헌 (122)

1. 1 Simon MC Keith B The role of oxygen availability in embryonic development and stem cell function Nat Rev Mol Cell Biol 2008 9 285 296 2876333 --> 18285802 

   상세보기

2. 2 Harris JM Esain V Frechette GM Harris LJ Cox AG Cortes M Garnaas MK Carroll KJ Cutting CC Khan T Elks PM Renshaw SA Dickinson BC Chang CJ Murphy MP Paw BH Vander Heiden MG Goessling W North TE Glucose metabolism impacts the spatiotemporal onset and magnitude of HSC induction in vivo Blood 2013 121 2483 2493 10.1182/blood-2012-12-471201 3612858 --> 23341543 

   상세보기

3. 3 Hom JR Quintanilla RA Hoffman DL de Mesy Bentley KL Molkentin JD Sheu SS Porter GA Jr The permeability transition pore controls cardiac mitochondrial maturation and myocyte differentiation Dev Cell 2011 21 469 478 3175092 --> 21920313 

   상세보기

4. 4 Holmström KM Finkel T Cellular mechanisms and physiological consequences of redox-dependent signalling Nat Rev Mol Cell Biol 2014 15 411 421 24854789 

   상세보기

5. 5 Liang R Ghaffari S Stem cells, redox signaling, and stem cell aging Antioxid Redox Signal 2014 20 1902 1916 3967383 --> 24383555 

   상세보기

6. 6 Gomes AP Price NL Ling AJ Moslehi JJ Montgomery MK Rajman L White JP Teodoro JS Wrann CD Hubbard BP Mercken EM Palmeira CM de Cabo R Rolo AP Turner N Bell EL Sinclair DA Declining NAD + induces a pseudohypoxic state disrupting nuclear-mitochondrial communication during aging Cell 2013 155 1624 1638 10.1016/j.cell.2013.11.037 4076149 --> 24360282 

   상세보기

7. 7 Rimmelé P Bigarella CL Liang R Izac B Dieguez-Gonzalez R Barbet G Donovan M Brugnara C Blander JM Sinclair DA Ghaffari S Aging-like phenotype and defective lineage specification in SIRT1-deleted hematopoietic stem and progenitor cells Stem Cell Reports 2014 3 44 59 10.1016/j.stemcr.2014.04.015 4110778 --> 25068121 

   상세보기

8. 8 Zachar V Duroux M Emmersen J Rasmussen JG Pennisi CP Yang S Fink T Hypoxia and adipose-derived stem cell-based tissue regeneration and engineering Expert Opin Biol Ther 2011 11 775 786 21413910 

   상세보기

9. 9 Eliasson P Jönsson JI The hematopoietic stem cell niche: low in oxygen but a nice place to be J Cell Physiol 2010 222 17 22 19725055 

   상세보기

10. 10 Harrison JS Rameshwar P Chang V Bandari P Oxygen saturation in the bone marrow of healthy volunteers Blood 2002 99 394 10.1182/blood.V99.1.394 11783438 

    상세보기

11. 11 Ivanovic Z Hypoxia or in situ normoxia: The stem cell paradigm J Cell Physiol 2009 219 271 275 10.1002/jcp.21690 19160417 

    상세보기

12. 12 Mohyeldin A Garzón-Muvdi T Quiñones-Hinojosa A Oxygen in stem cell biology: a critical component of the stem cell niche Cell Stem Cell 2010 7 150 161 10.1016/j.stem.2010.07.007 20682444 

    상세보기

13. 13 Dhimitruka I Bobko AA Eubank TD Komarov DA Khramtsov VV Phosphonated trityl probes for concurrent in vivo tissue oxygen and pH monitoring using electron paramagnetic resonance-based techniques J Am Chem Soc 2013 135 5904 5910 10.1021/ja401572r 3982387 --> 23517077 

    상세보기

14. 14 Kaewsuwan S Song SY Kim JH Sung JH Mimicking the functional niche of adipose-derived stem cells for regenerative medicine Expert Opin Biol Ther 2012 12 1575 1588 10.1517/14712598.2012.721763 22953993 

    상세보기

15. 15 Rodesch F Simon P Donner C Jauniaux E Oxygen measurements in endometrial and trophoblastic tissues during early pregnancy Obstet Gynecol 1992 80 283 285 1635745 

    상세보기

16. 16 Ezashi T Das P Roberts RM Low O 2 tensions and the prevention of differentiation of hES cells Proc Natl Acad Sci U S A 2005 102 4783 4788 10.1073/pnas.0501283102 554750 --> 15772165 

    상세보기

17. 17 Närvä E Pursiheimo JP Laiho A Rahkonen N Emani MR Viitala M Laurila K Sahla R Lund R Lähdesmäki H Jaakkola P Lahesmaa R Continuous hypoxic culturing of human embryonic stem cells enhances SSEA-3 and MYC levels PLoS One 2013 8 e78847 10.1371/journal.pone.0078847 3827269 --> 24236059 

    상세보기

18. 18 Pollard PJ Kranc KR Hypoxia signaling in hematopoietic stem cells: a double-edged sword Cell Stem Cell 2010 7 276 278 10.1016/j.stem.2010.08.006 20804963 

    상세보기

19. 19 Lee SH Lee MY Han HJ Short-period hypoxia increases mouse embryonic stem cell proliferation through cooperation of arachidonic acid and PI3K/Akt signalling pathways Cell Prolif 2008 41 230 247 10.1111/j.1365-2184.2008.00516.x 18336469 

    상세보기

20. 20 Lee SH Lee YJ Han HJ Role of hypoxia-induced fibronectin-integrin β1 expression in embryonic stem cell proliferation and migration: Involvement of PI3K/Akt and FAK J Cell Physiol 2011 226 484 493 10.1002/jcp.22358 20677223 

    상세보기

21. 21 Finkel T Oxidant signals and oxidative stress Curr Opin Cell Biol 2003 15 247 254 10.1016/S0955-0674(03)00002-4 12648682 

    상세보기

22. 22 Janssen-Heininger YM Mossman BT Heintz NH Forman HJ Kalyanaraman B Finkel T Stamler JS Rhee SG van der Vliet A Redox-based regulation of signal transduction: principles, pitfalls, and promises Free Radic Biol Med 2008 45 1 17 10.1016/j.freeradbiomed.2008.03.011 2453533 --> 18423411 

    상세보기

23. 23 Dröge W Aging-related changes in the thiol/disulfide redox state: implications for the use of thiol antioxidants Exp Gerontol 2002 37 1333 1345 10.1016/S0531-5565(02)00175-4 12559403 

    상세보기

24. 24 Tahara EB Navarete FD Kowaltowski AJ Tissue-, substrate-, and site-specific characteristics of mitochondrial reactive oxygen species generation Free Radic Biol Med 2009 46 1283 1297 10.1016/j.freeradbiomed.2009.02.008 19245829 

    상세보기

25. 25 Brand MD The sites and topology of mitochondrial super-oxide production Exp Gerontol 2010 45 466 472 10.1016/j.exger.2010.01.003 2879443 --> 20064600 

    상세보기

26. 26 Mailloux RJ Harper ME Mitochondrial proticity and ROS signaling: lessons from the uncoupling proteins Trends Endocrinol Metab 2012 23 451 458 10.1016/j.tem.2012.04.004 22591987 

    상세보기

27. 27 Rustin P Munnich A Rötig A Succinate dehydrogenase and human diseases: new insights into a well-known enzyme Eur J Hum Genet 2002 10 289 291 10.1038/sj.ejhg.5200793 12082502 

    상세보기

28. 28 Nathan C Cunningham-Bussel A Beyond oxidative stress: an immunologist's guide to reactive oxygen species Nat Rev Immunol 2013 13 349 361 10.1038/nri3423 4250048 --> 23618831 

    상세보기

29. 29 Forman HJ Kennedy J Superoxide production and electron transport in mitochondrial oxidation of dihydroorotic acid J Biol Chem 1975 250 4322 4326 165196 

30. 30 Tretter L Adam-Vizi V Generation of reactive oxygen species in the reaction catalyzed by α-ketoglutarate dehydrogenase J Neurosci 2004 24 7771 7778 10.1523/JNEUROSCI.1842-04.2004 15356188 

    상세보기

31. 31 Gazaryan IG Krasnikov BF Ashby GA Thorneley RN Kristal BS Brown AM Zinc is a potent inhibitor of thiol oxidoreductase activity and stimulates reactive oxygen species production by lipoamide dehydrogenase J Biol Chem 2002 277 10064 10072 10.1074/jbc.M108264200 11744691 

    상세보기

32. 32 Anastasiou D Poulogiannis G Asara JM Boxer MB Jiang JK Shen M Bellinger G Sasaki AT Locasale JW Auld DS Thomas CJ Vander Heiden MG Cantley LC Inhibition of pyruvate kinase M2 by reactive oxygen species contributes to cellular antioxidant responses Science 2011 334 1278 1283 10.1126/science.1211485 3471535 --> 22052977 

    상세보기

33. 33 Sarbassov DD Sabatini DM Redox regulation of the nutrient-sensitive raptor-mTOR pathway and complex J Biol Chem 2005 280 39505 39509 10.1074/jbc.M506096200 16183647 

    상세보기

34. 34 Dansen TB Smits LM van Triest MH de Keizer PL van Leenen D Koerkamp MG Szypowska A Meppelink A Brenkman AB Yodoi J Holstege FC Burgering BM Redox-sensitive cysteines bridge p300/CBP-mediated acetylation and FoxO4 activity Nat Chem Biol 2009 5 664 672 10.1038/nchembio.194 19648934 

    상세보기

35. 35 Guo Z Kozlov S Lavin MF Person MD Paull TT ATM activation by oxidative stress Science 2010 330 517 521 10.1126/science.1192912 20966255 

    상세보기

36. 36 Guo YL Chakraborty S Rajan SS Wang R Huang F Effects of oxidative stress on mouse embryonic stem cell proliferation, apoptosis, senescence, and self-renewal Stem Cells Dev 2010 19 1321 1331 10.1089/scd.2009.0313 3128305 --> 20092403 

    상세보기

37. 37 Forsyth NR Musio A Vezzoni P Simpson AH Noble BS McWhir J Physiologic oxygen enhances human embryonic stem cell clonal recovery and reduces chromosomal abnormalities Cloning Stem Cells 2006 8 16 23 10.1089/clo.2006.8.16 16571074 

    상세보기

38. 38 Urao N Ushio-Fukai M Redox regulation of stem/progenitor cells and bone marrow niche Free Radic Biol Med 2013 54 26 39 10.1016/j.freeradbiomed.2012.10.532 3637653 --> 23085514 

    상세보기

39. 39 Folmes CD Dzeja PP Nelson TJ Terzic A Metabolic plasticity in stem cell homeostasis and differentiation Cell Stem Cell 2012 11 596 606 10.1016/j.stem.2012.10.002 3593051 --> 23122287 

    상세보기

40. 40 Prigione A Fauler B Lurz R Lehrach H Adjaye J The senescence-related mitochondrial/oxidative stress pathway is repressed in human induced pluripotent stem cells Stem Cells 2010 28 721 733 10.1002/stem.404 20201066 

    상세보기

41. 41 Zhang J Khvorostov I Hong JS Oktay Y Vergnes L Nuebel E Wahjudi PN Setoguchi K Wang G Do A Jung HJ McCaffery JM Kurland IJ Reue K Lee WN Koehler CM Teitell MA UCP2 regulates energy metabolism and differentiation potential of human pluripotent stem cells EMBO J 2011 30 4860 4873 3243621 --> 22085932 

42. 42 Ward PS Thompson CB Metabolic reprogramming: a cancer hallmark even warburg did not anticipate Cancer Cell 2012 21 297 308 10.1016/j.ccr.2012.02.014 3311998 --> 22439925 

    상세보기

43. 43 Mandal S Lindgren AG Srivastava AS Clark AT Banerjee U Mitochondrial function controls proliferation and early differentiation potential of embryonic stem cells Stem Cells 2011 29 486 495 10.1002/stem.590 4374603 --> 21425411 

    상세보기

44. 44 Zhou W Choi M Margineantu D Margaretha L Hesson J Cavanaugh C Blau CA Horwitz MS Hockenbery D Ware C Ruohola-Baker H HIF1α induced switch from bivalent to exclusively glycolytic metabolism during ESC- to-EpiSC/hESC transition EMBO J 2012 31 2103 2116 3343469 --> 22446391 

45. 45 Han MK Song EK Guo Y Ou X Mantel C Broxmeyer HE SIRT1 regulates apoptosis and Nanog expression in mouse embryonic stem cells by controlling p53 subcellular localization Cell Stem Cell 2008 2 241 251 10.1016/j.stem.2008.01.002 2819008 --> 18371449 

    상세보기

46. 46 Zhang X Yalcin S Lee DF Yeh TY Lee SM Su J Mungamuri SK Rimmelé P Kennedy M Sellers R Landthaler M Tuschl T Chi NW Lemischka I Keller G Ghaffari S FOXO1 is an essential regulator of pluripotency in human embryonic stem cells Nat Cell Biol 2011 13 1092 1099 4053529 --> 21804543 

    상세보기

47. 47 van den Berg MC Burgering BM Integrating opposing signals toward Forkhead box O Antioxid Redox Signal 2011 14 607 621 20624032 

    상세보기

48. 48 Shenoy A Blelloch RH Regulation of microRNA function in somatic stem cell proliferation and differentiation Nat Rev Mol Cell Biol 2014 15 565 576 4377327 --> 25118717 

    상세보기

49. 49 Kim BS Jung JS Jang JH Kang KS Kang SK Nuclear Argonaute 2 regulates adipose tissue-derived stem cell survival through direct control of miR10b and selenoprotein N1 expression Aging Cell 2011 10 277 291 10.1111/j.1474-9726.2011.00670.x 21241449 

    상세보기

50. 50 Xu J Huang Z Lin L Fu M Gao Y Shen Y Zou Y Sun A Qian J Ge J miR-210 over-expression enhances mesenchymal stem cell survival in an oxidative stress environment through antioxidation and c-Met pathway activation Sci China Life Sci 2014 57 989 997 25168379 

51. 51 Shepard TH Muffley LA Smith LT Mitochondrial ultra-structure in embryos after implantation Hum Reprod 2000 15 Suppl 2 218 228 10.1093/humrep/15.suppl_2.218 11041527 

    상세보기

52. 52 Armstrong L Tilgner K Saretzki G Atkinson SP Stojkovic M Moreno R Przyborski S Lako M Human induced pluripotent stem cell lines show stress defense mechanisms and mitochondrial regulation similar to those of human embryonic stem cells Stem Cells 2010 28 661 673 10.1002/stem.307 20073085 

    상세보기

53. 53 Chen CT Shih YR Kuo TK Lee OK Wei YH Coordinated changes of mitochondrial biogenesis and anti-oxidant enzymes during osteogenic differentiation of human mesenchymal stem cells Stem Cells 2008 26 960 968 10.1634/stemcells.2007-0509 18218821 

    상세보기

54. 54 Sena LA Chandel NS Physiological roles of mitochondrial reactive oxygen species Mol Cell 2012 48 158 167 10.1016/j.molcel.2012.09.025 3484374 --> 23102266 

    상세보기

55. 55 Buggisch M Ateghang B Ruhe C Strobel C Lange S Wartenberg M Sauer H Stimulation of ES-cell-derived cardiomyogenesis and neonatal cardiac cell proliferation by reactive oxygen species and NADPH oxidase J Cell Sci 2007 120 885 894 10.1242/jcs.03386 17298980 

    상세보기

56. 56 Sharifpanah F Wartenberg M Hannig M Piper HM Sauer H Peroxisome proliferator-activated receptor α agonists enhance cardiomyogenesis of mouse ES cells by utilization of a reactive oxygen species-dependent mechanism Stem Cells 2008 26 64 71 10.1634/stemcells.2007-0532 17951219 

    상세보기

57. 57 Crespo FL Sobrado VR Gomez L Cervera AM McCreath KJ Mitochondrial reactive oxygen species mediate cardiomyocyte formation from embryonic stem cells in high glucose Stem Cells 2010 28 1132 1142 20506541 

    상세보기

58. 58 Xiao Q Luo Z Pepe AE Margariti A Zeng L Xu Q Embryonic stem cell differentiation into smooth muscle cells is mediated by Nox4-produced H 2 O 2 Am J Physiol Cell Physiol 2009 296 C711 C723 10.1152/ajpcell.00442.2008 19036941 

    상세보기

59. 59 Kanda Y Hinata T Kang SW Watanabe Y Reactive oxygen species mediate adipocyte differentiation in mesenchymal stem cells Life Sci 2011 89 250 258 10.1016/j.lfs.2011.06.007 21722651 

    상세보기

60. 60 Mouche S Mkaddem SB Wang W Katic M Tseng YH Carnesecchi S Steger K Foti M Meier CA Muzzin P Kahn CR Ogier-Denis E Szanto I Reduced expression of the NADPH oxidase NOX4 is a hallmark of adipocyte differentiation Biochim Biophys Acta 2007 1773 1015 1027 10.1016/j.bbamcr.2007.03.003 17553579 

    상세보기

61. 61 Cho YM Kwon S Pak YK Seol HW Choi YM Park do J Park KS Lee HK Dynamic changes in mitochondrial biogenesis and antioxidant enzymes during the spontaneous differentiation of human embryonic stem cells Biochem Biophys Res Commun 2006 348 1472 1478 10.1016/j.bbrc.2006.08.020 16920071 

    상세보기

62. 62 Facucho-Oliveira JM Alderson J Spikings EC Egginton S St John JC Mitochondrial DNA replication during differentiation of murine embryonic stem cells J Cell Sci 2007 120 4025 4034 10.1242/jcs.016972 17971411 

    상세보기

63. 63 Facucho-Oliveira JM St John JC The relationship between pluripotency and mitochondrial DNA proliferation during early embryo development and embryonic stem cell differentiation Stem Cell Rev 2009 5 140 158 10.1007/s12015-009-9058-0 19521804 

    상세보기

64. 64 Suhr ST Chang EA Tjong J Alcasid N Perkins GA Goissis MD Ellisman MH Perez GI Cibelli JB Mitochondrial rejuvenation after induced pluripotency PLoS One 2010 5 e14095 10.1371/journal.pone.0014095 2991355 --> 21124794 

    상세보기

65. 65 Ballabeni A Park IH Zhao R Wang W Lerou PH Daley GQ Kirschner MW Cell cycle adaptations of embryonic stem cells Proc Natl Acad Sci U S A 2011 108 19252 19257 10.1073/pnas.1116794108 3228440 --> 22084091 

    상세보기

66. 66 Folmes CD Nelson TJ Martinez-Fernandez A Arrell DK Lindor JZ Dzeja PP Ikeda Y Perez-Terzic C Terzic A Somatic oxidative bioenergetics transitions into pluripotency-dependent glycolysis to facilitate nuclear reprogramming Cell Metab 2011 14 264 271 10.1016/j.cmet.2011.06.011 3156138 --> 21803296 

    상세보기

67. 67 Rehman J Empowering self-renewal and differentiation: the role of mitochondria in stem cells J Mol Med (Berl) 2010 88 981 986 10.1007/s00109-010-0678-2 20809088 

    상세보기

68. 68 Varum S Rodrigues AS Moura MB Momcilovic O Easley CA 4th Ramalho-Santos J Van Houten B Schatten G Energy metabolism in human pluripotent stem cells and their differentiated counterparts PLoS One 2011 6 e20914 10.1371/journal.pone.0020914 3117868 --> 21698063 

    상세보기

69. 69 Panopoulos AD Yanes O Ruiz S Kida YS Diep D Tautenhahn R Herrerías A Batchelder EM Plongthongkum N Lutz M Berggren WT Zhang K Evans RM Siuzdak G Izpisua Belmonte JC The metabolome of induced pluripotent stem cells reveals metabolic changes occurring in somatic cell reprogramming Cell Res 2012 22 168 177 10.1038/cr.2011.177 3252494 --> 22064701 

    상세보기

70. 70 Kondoh H Lleonart ME Gil J Wang J Degan P Peters G Martinez D Carnero A Beach D Glycolytic enzymes can modulate cellular life span Cancer Res 2005 65 177 185 15665293 

    상세보기

71. 71 Filosa S Fico A Paglialunga F Balestrieri M Crooke A Verde P Abrescia P Bautista JM Martini G Failure to increase glucose consumption through the pentose-phosphate pathway results in the death of glucose-6-phosphate dehydrogenase gene-deleted mouse embryonic stem cells subjected to oxidative stress Biochem J 2003 370 935 943 12466018 

72. 72 Forristal CE Wright KL Hanley NA Oreffo RO Houghton FD Hypoxia inducible factors regulate pluripotency and proliferation in human embryonic stem cells cultured at reduced oxygen tensions Reproduction 2010 139 85 97 10.1530/REP-09-0300 19755485 

    상세보기

73. 73 Lee SH Heo JS Han HJ Effect of hypoxia on 2-deoxy-glucose uptake and cell cycle regulatory protein expression of mouse embryonic stem cells: involvement of Ca 2+ /PKC, MAPKs and HIF-1α Cell Physiol Biochem 2007 19 269 282 17495467 

74. 74 Yoshida Y Takahashi K Okita K Ichisaka T Yamanaka S Hypoxia enhances the generation of induced pluripotent stem cells Cell Stem Cell 2009 5 237 241 10.1016/j.stem.2009.08.001 19716359 

    상세보기

75. 75 Maynard S Swistowska AM Lee JW Liu Y Liu ST Da Cruz AB Rao M de Souza-Pinto NC Zeng X Bohr VA Human embryonic stem cells have enhanced repair of multiple forms of DNA damage Stem Cells 2008 26 2266 2274 10.1634/stemcells.2007-1041 2574957 --> 18566332 

    상세보기

76. 76 Saretzki G Walter T Atkinson S Passos JF Bareth B Keith WN Stewart R Hoare S Stojkovic M Armstrong L von Zglinicki T Lako M Downregulation of multiple stress defense mechanisms during differentiation of human embryonic stem cells Stem Cells 2008 26 455 464 10.1634/stemcells.2007-0628 18055443 

    상세보기

77. 77 Hansson J Rafiee MR Reiland S Polo JM Gehring J Okawa S Huber W Hochedlinger K Krijgsveld J Highly coordinated proteome dynamics during reprogramming of somatic cells to pluripotency Cell Rep 2012 2 1579 1592 4438680 --> 23260666 

    상세보기

78. 78 Kobayashi CI Suda T Regulation of reactive oxygen species in stem cells and cancer stem cells J Cell Physiol 2012 227 421 430 21448925 

    상세보기

79. 79 Suda T Takubo K Semenza GL Metabolic regulation of hematopoietic stem cells in the hypoxic niche Cell Stem Cell 2011 9 298 310 10.1016/j.stem.2011.09.010 21982230 

    상세보기

80. 80 Kocabas F Zheng J Thet S Copeland NG Jenkins NA DeBerardinis RJ Zhang C Sadek HA Meis1 regulates the metabolic phenotype and oxidant defense of hematopoietic stem cells Blood 2012 120 4963 4972 10.1182/blood-2012-05-432260 3525021 --> 22995899 

    상세보기

81. 81 Zhang CC Sadek HA Hypoxia and metabolic properties of hematopoietic stem cells Antioxid Redox Signal 2014 20 1891 1901 10.1089/ars.2012.5019 3967354 --> 23621582 

    상세보기

82. 82 Candelario KM Shuttleworth CW Cunningham LA Neural stem/progenitor cells display a low requirement for oxidative metabolism independent of hypoxia inducible factor-1α expression J Neurochem 2013 125 420 429 10.1111/jnc.12204 4204647 --> 23410250 

    상세보기

83. 83 Fehrer C Brunauer R Laschober G Unterluggauer H Reitinger S Kloss F Gülly C Gassner R Lepperdinger G Reduced oxygen tension attenuates differentiation capacity of human mesenchymal stem cells and prolongs their lifespan Aging Cell 2007 6 745 757 10.1111/j.1474-9726.2007.00336.x 17925003 

    상세보기

84. 84 Ryu JM Han HJ L-threonine regulates G1/S phase transition of mouse embryonic stem cells via PI3K/Akt, MAPKs, and mTORC pathways J Biol Chem 2011 286 23667 23678 10.1074/jbc.M110.216283 3129147 --> 21550972 

    상세보기

85. 85 Wang J Alexander P Wu L Hammer R Cleaver O McKnight SL Dependence of mouse embryonic stem cells on threonine catabolism Science 2009 325 435 439 10.1126/science.1173288 4373593 --> 19589965 

    상세보기

86. 86 Ito K Suda T Metabolic requirements for the maintenance of self-renewing stem cells Nat Rev Mol Cell Biol 2014 15 243 256 10.1038/nrm3772 4095859 --> 24651542 

    상세보기

87. 87 Carey BW Finley LW Cross JR Allis CD Thompson CB Intracellular α-ketoglutarate maintains the pluripotency of embryonic stem cells Nature 2015 518 413 416 10.1038/nature13981 25487152 

    상세보기

88. 88 Gao P Tchernyshyov I Chang TC Lee YS Kita K Ochi T Zeller KI De Marzo AM Van Eyk JE Mendell JT Dang CV c-Myc suppression of miR-23a/b enhances mitochondrial glutaminase expression and glutamine metabolism Nature 2009 458 762 765 10.1038/nature07823 2729443 --> 19219026 

    상세보기

89. 89 Son J Lyssiotis CA Ying H Wang X Hua S Ligorio M Perera RM Ferrone CR Mullarky E Shyh-Chang N Kang Y Fleming JB Bardeesy N Asara JM Haigis MC DePinho RA Cantley LC Kimmelman AC Glutamine supports pancreatic cancer growth through a KRAS-regulated metabolic pathway Nature 2013 496 101 105 10.1038/nature12040 3656466 --> 23535601 

    상세보기

90. 90 Wise DR DeBerardinis RJ Mancuso A Sayed N Zhang XY Pfeiffer HK Nissim I Daikhin E Yudkoff M McMahon SB Thompson CB Myc regulates a transcriptional program that stimulates mitochondrial glutaminolysis and leads to glutamine addiction Proc Natl Acad Sci U S A 2008 105 18782 18787 10.1073/pnas.0810199105 2596212 --> 19033189 

    상세보기

91. 91 Häberle J Görg B Rutsch F Schmidt E Toutain A Benoist JF Gelot A Suc AL Höhne W Schliess F Häussinger D Koch HG Congenital glutamine deficiency with glutamine synthetase mutations N Engl J Med 2005 353 1926 1933 16267323 

    상세보기

92. 92 Häberle J Görg B Toutain A Rutsch F Benoist JF Gelot A Suc AL Koch HG Schliess F Häussinger D Inborn error of amino acid synthesis: human glutamine synthetase deficiency J Inherit Metab Dis 2006 29 352 358 16763901 

    상세보기

93. 93 Holleran AL Briscoe DA Fiskum G Kelleher JK Glutamine metabolism in AS-30D hepatoma cells. Evidence for its conversion into lipids via reductive carboxylation Mol Cell Biochem 1995 152 95 101 8751155 

    상세보기

94. 94 Metallo CM Gameiro PA Bell EL Mattaini KR Yang J Hiller K Jewell CM Johnson ZR Irvine DJ Guarente L Kelleher JK Vander Heiden MG Iliopoulos O Stephanopoulos G Reductive glutamine metabolism by IDH1 mediates lipogenesis under hypoxia Nature 2011 481 380 384 3710581 --> 22101433 

95. 95 Wise DR Ward PS Shay JE Cross JR Gruber JJ Sachdeva UM Platt JM DeMatteo RG Simon MC Thompson CB Hypoxia promotes isocitrate dehydrogenase-dependent carboxylation of α-ketoglutarate to citrate to support cell growth and viability Proc Natl Acad Sci U S A 2011 108 19611 19616 3241793 --> 22106302 

96. 96 Ferber EC Peck B Delpuech O Bell GP East P Schulze A FOXO3a regulates reactive oxygen metabolism by inhibiting mitochondrial gene expression Cell Death Differ 2012 19 968 979 3354049 --> 22139133 

    상세보기

97. 97 Jensen KS Binderup T Jensen KT Therkelsen I Borup R Nilsson E Multhaupt H Bouchard C Quistorff B Kjaer A Landberg G Staller P FoxO3A promotes metabolic adaptation to hypoxia by antagonizing Myc function EMBO J 2011 30 4554 4570 3243591 --> 21915097 

    상세보기

98. 98 Whillier S Garcia B Chapman BE Kuchel PW Raftos JE Glutamine and α-ketoglutarate as glutamate sources for glutathione synthesis in human erythrocytes FEBS J 2011 278 3152 3163 21749648 

    상세보기

99. 99 Yeo H Lyssiotis CA Zhang Y Ying H Asara JM Cantley LC Paik JH FoxO3 coordinates metabolic pathways to maintain redox balance in neural stem cells EMBO J 2013 32 2589 2602 3791369 --> 24013118 

    상세보기

100. 100 Kim YH Heo JS Han HJ High glucose increase cell cycle regulatory proteins level of mouse embryonic stem cells via PI3-K/Akt and MAPKs signal pathways J Cell Physiol 2006 209 94 102 16775839 

     상세보기

101. 101 Gameiro PA Yang J Metelo AM Pérez-Carro R Baker R Wang Z Arreola A Rathmell WK Olumi A López-Larrubia P Stephanopoulos G Iliopoulos O In vivo HIF-mediated reductive carboxylation is regulated by citrate levels and sensitizes VHL-deficient cells to glutamine deprivation Cell Metab 2013 17 372 385 10.1016/j.cmet.2013.02.002 4003458 --> 23473032 

     상세보기

102. 102 Pompéia C Lopes LR Miyasaka CK Procópio J Sannomiya P Curi R Effect of fatty acids on leukocyte function Braz J Med Biol Res 2000 33 1255 1268 10.1590/S0100-879X2000001100001 11050654 

     상세보기

103. 103 Kuhajda FP Jenner K Wood FD Hennigar RA Jacobs LB Dick JD Pasternack GR Fatty acid synthesis: a potential selective target for antineoplastic therapy Proc Natl Acad Sci U S A 1994 91 6379 6383 10.1073/pnas.91.14.6379 44205 --> 8022791 

     상세보기

104. 104 Menendez JA Lupu R Fatty acid synthase and the lipogenic phenotype in cancer pathogenesis Nat Rev Cancer 2007 7 763 777 10.1038/nrc2222 17882277 

     상세보기

105. 105 Li J Bosch-Marce M Nanayakkara A Savransky V Fried SK Semenza GL Polotsky VY Altered metabolic responses to intermittent hypoxia in mice with partial deficiency of hypoxia-inducible factor-1α Physiol Genomics 2006 25 450 457 10.1152/physiolgenomics.00293.2005 16507783 

     상세보기

106. 106 Lee HJ Ryu JM Jung YH Oh SY Lee SJ Han HJ Novel pathway for hypoxia-induced proliferation and migration in human mesenchymal stem cells: Involvement of HIF-1α, FASN, and mTORC1 Stem Cells 2015 Epub ahead of print 10.1002/stem.2020 

     상세보기

107. 107 Pelicano H Xu RH Du M Feng L Sasaki R Carew JS Hu Y Ramdas L Hu L Keating MJ Zhang W Plunkett W Huang P Mitochondrial respiration defects in cancer cells cause activation of Akt survival pathway through a redox-mediated mechanism J Cell Biol 2006 175 913 923 10.1083/jcb.200512100 2064701 --> 17158952 

     상세보기

108. 108 Storz P Forkhead homeobox type O transcription factors in the responses to oxidative stress Antioxid Redox Signal 2011 14 593 605 10.1089/ars.2010.3405 3038124 --> 20618067 

     상세보기

109. 109 Essers MA Weijzen S de Vries-Smits AM Saarloos I de Ruiter ND Bos JL Burgering BM FOXO transcription factor activation by oxidative stress mediated by the small GTPase Ral and JNK EMBO J 2004 23 4802 4812 10.1038/sj.emboj.7600476 535088 --> 15538382 

     상세보기

110. 110 Nakae J Kitamura T Kitamura Y Biggs WH 3rd Arden KC Accili D The forkhead transcription factor Foxo1 regulates adipocyte differentiation Dev Cell 2003 4 119 129 10.1016/S1534-5807(02)00401-X 12530968 

     상세보기

111. 111 Munekata K Sakamoto K Forkhead transcription factor Foxo1 is essential for adipocyte differentiation In Vitro Cell Dev Biol Anim 2009 45 642 651 10.1007/s11626-009-9230-5 19585174 

     상세보기

112. 112 Kojima T Norose T Tsuchiya K Sakamoto K Mouse 3T3-L1 cells acquire resistance against oxidative stress as the adipocytes differentiate via the transcription factor FoxO Apoptosis 2010 15 83 93 10.1007/s10495-009-0415-x 19842039 

     상세보기

113. 113 Calzadilla P Sapochnik D Cosentino S Diz V Dicelio L Calvo JC Guerra LN N-acetylcysteine reduces markers of differentiation in 3T3-L1 adipocytes Int J Mol Sci 2011 12 6936 6951 10.3390/ijms12106936 3211019 --> 22072928 

     상세보기

114. 114 Krey G Braissant O L'Horset F Kalkhoven E Perroud M Parker MG Wahli W Fatty acids, eicosanoids, and hypolipidemic agents identified as ligands of peroxisome proliferator-activated receptors by coactivator-dependent receptor ligand assay Mol Endocrinol 1997 11 779 791 10.1210/mend.11.6.0007 9171241 

     상세보기

115. 115 Calkin AC Thomas MC PPAR Agonists and Cardiovascular Disease in Diabetes PPAR Res 2008 2008 245410 10.1155/2008/245410 2233765 --> 18288280 

     상세보기

116. 116 Vergori L Lauret E Gaceb A Beauvillain C Andriantsitohaina R Martinez MC PPARα regulates endothelial progenitor cell maturation and myeloid lineage differentiation through a NADPH oxidase-dependent mechanism in mice Stem Cells 2015 33 1292 1303 10.1002/stem.1924 25524540 

     상세보기

117. 117 Madsen L Petersen RK Kristiansen K Regulation of adipocyte differentiation and function by polyunsaturated fatty acids Biochim Biophys Acta 2005 1740 266 286 10.1016/j.bbadis.2005.03.001 15949694 

     상세보기

118. 118 Poli G Leonarduzzi G Biasi F Chiarpotto E Oxidative stress and cell signalling Curr Med Chem 2004 11 1163 1182 10.2174/0929867043365323 15134513 

     상세보기

119. 119 Ryu JM Baek YB Shin MS Park JH Park SH Lee JH Han HJ Sphingosine-1-phosphate-induced Flk-1 trans-activation stimulates mouse embryonic stem cell proliferation through S1P1/S1P3-dependent β-arrestin/c-Src pathways Stem Cell Res 2014 12 69 85 10.1016/j.scr.2013.08.013 24145189 

     상세보기

120. 120 Ryu JM Han HJ Autotaxin-LPA axis regulates hMSC migration by adherent junction disruption and cytoskeletal rearrangement via LPAR1/3-dependent PKC/GSK3β/β-catenin and PKC/Rho GTPase pathways Stem Cells 2015 33 819 832 10.1002/stem.1882 25376707 

     상세보기

121. 121 Park SS Kim MO Yun SP Ryu JM Park JH Seo BN Jeon JH Han HJ C 16 -Ceramide-induced F-actin regulation stimulates mouse embryonic stem cell migration: involvement of N-WASP/Cdc42/Arp2/3 complex and cofilin-1/α-actinin Biochim Biophys Acta 2013 1831 350 360 22989773 

122. 122 Bigarella CL Liang R Ghaffari S Stem cells and the impact of ROS signaling Development 2014 141 4206 4218 10.1242/dev.107086 4302918 --> 25371358 

     상세보기