$\require{mediawiki-texvc}$

연합인증

연합인증 가입 기관의 연구자들은 소속기관의 인증정보(ID와 암호)를 이용해 다른 대학, 연구기관, 서비스 공급자의 다양한 온라인 자원과 연구 데이터를 이용할 수 있습니다.

이는 여행자가 자국에서 발행 받은 여권으로 세계 각국을 자유롭게 여행할 수 있는 것과 같습니다.

연합인증으로 이용이 가능한 서비스는 NTIS, DataON, Edison, Kafe, Webinar 등이 있습니다.

한번의 인증절차만으로 연합인증 가입 서비스에 추가 로그인 없이 이용이 가능합니다.

다만, 연합인증을 위해서는 최초 1회만 인증 절차가 필요합니다. (회원이 아닐 경우 회원 가입이 필요합니다.)

연합인증 절차는 다음과 같습니다.

최초이용시에는
ScienceON에 로그인 → 연합인증 서비스 접속 → 로그인 (본인 확인 또는 회원가입) → 서비스 이용

그 이후에는
ScienceON 로그인 → 연합인증 서비스 접속 → 서비스 이용

연합인증을 활용하시면 KISTI가 제공하는 다양한 서비스를 편리하게 이용하실 수 있습니다.

The exercise‐induced biochemical milieu enhances collagen content and tensile strength of engineered ligaments 원문보기

The Journal of physiology, v.593 no.20, 2015년, pp.4665 - 4675  

West, Daniel W. D. (Department of Physiology and Membrane Biology, University of California Davis, One Shields Ave, Davis, CA, 95616, USA) ,  Lee‐Barthel, Ann (Department of Biomedical Engineering, University of California Davis, One Shields Ave, Davis, CA, 95616, USA) ,  McIntyre, Todd (Department of Biomedical Engineering, University of California Davis, One Shields Ave, Davis, CA, 95616, USA) ,  Shamim, Baubak (Department of Neurobiology, Physiology and Behaviour, University of California Davis, One Shields Ave, Davis, CA, 95616, USA) ,  Lee, Cassandra A. (Department of Orthopaedic Surgery, University of California Davis, One Shields Ave, Davis, CA, 95616, USA) ,  Baar, Keith (Department of Physiology and Membrane Biology, University of California Davis, One Shields Ave, Davis, CA, 95616, USA)

Abstract AI-Helper 아이콘AI-Helper

Key pointsExercise acutely increases the concentrations of metabolites and hormones such as growth hormone (GH) and, to a lesser extent, insulin‐like growth factor 1 (IGF‐1); however, the biological function of this response is unclear.Pharmacological administration of these hormones sti...

참고문헌 (51)

  1. Baehr LM , Tunzi M & Bodine SC ( 2014 ). Muscle hypertrophy is associated with increases in proteasome activity that is independent of MuRF1 and MAFbx expression . Front Physiol 5 , 69 . 

  2. Barton‐Davis ER , Shoturma DI , Musaro A , Rosenthal N & Sweeney HL ( 1998 ). Viral mediated expression of insulin‐like growth factor I blocks the aging‐related loss of skeletal muscle function . Proc Natl Acad Sci U S A 95 , 15603 – 15607 . 

  3. Bayer ML , Yeung CY , Kadler KE , Qvortrup K , Baar K , Svensson RB , Magnusson SP , Krogsgaard M , Koch M & Kjaer M ( 2010 ). The initiation of embryonic‐like collagen fibrillogenesis by adult human tendon fibroblasts when cultured under tension . Biomaterials 31 , 4889 – 4897 . 

  4. Boesen AP , Dideriksen K , Couppe C , Magnusson SP , Schjerling P , Boesen M , Aagaard P , Kjaer M & Langberg H ( 2014 ). Effect of growth hormone on aging connective tissue in muscle and tendon: gene expression, morphology, and function following immobilization and rehabilitation . J Appl Physiol 116 , 192 – 203 . 

  5. Brune T , Borel A , Gilbert TW , Fraceschi JP , Badylak SF & Sommer P ( 2007 ). In vitro comparison of human fibroblasts from intact and ruptured ACL for use in tissue engineering . Eur Cells Mater 14 , 78 – 90 . 

  6. Calve S , Lytle IF , Grosh K , Brown DL & Arruda EM ( 2010 ). Implantation increases tensile strength and collagen content of self‐assembled tendon constructs . J Appl Physiol 108 , 875 – 881 . 

  7. Chen SJ , Yuan W , Mori Y , Levenson A , Trojanowska M & Varga J ( 1999 ). Stimulation of type I collagen transcription in human skin fibroblasts by TGF‐β: involvement of Smad 3 . J Invest Dermatol 112 , 49 – 57 . 

  8. Crane JD , MacNeil LG , Lally JS , Ford RJ , Bujak AL , Brar IK , Kemp BE , Raha S , Steinberg GR & Tarnopolsky MA ( 2015 ). Exercise‐stimulated interleukin‐15 is controlled by AMPK and regulates skin metabolism and aging . Aging Cell 14 , 625 – 634 . 

  9. Creemers LB , Jansen DC , van Veen‐Reurings A , van den Bos T & Everts V ( 1997 ). Microassay for the assessment of low levels of hydroxyproline . Biotechniques 22 , 656 – 658 . 

  10. Dodt C , Breckling U , Derad I , Fehm HL & Born J ( 1997 ). Plasma epinephrine and norepinephrine concentrations of healthy humans associated with nighttime sleep and morning arousal . Hypertension 30 , 71 – 76 . 

  11. Doessing S , Heinemeier KM , Holm L , Mackey AL , Schjerling P , Rennie M , Smith K , Reitelseder S , Kappelgaard AM , Rasmussen MH , Flyvbjerg A & Kjaer M ( 2010 a ). Growth hormone stimulates the collagen synthesis in human tendon and skeletal muscle without affecting myofibrillar protein synthesis . J Physiol 588 , 341 – 351 . 

  12. Doessing S , Holm L , Heinemeier KM , Feldt‐Rasmussen U , Schjerling P , Qvortrup K , Larsen JO , Nielsen RH , Flyvbjerg A & Kjaer M ( 2010 b ). GH and IGF1 levels are positively associated with musculotendinous collagen expression: experiments in acromegalic and GH deficiency patients . Eur J Endocrinol 163 , 853 – 862 . 

  13. Doessing S & Kjaer M ( 2005 ). Growth hormone and connective tissue in exercise . Scand J Med Sci Sports 15 , 202 – 210 . 

  14. Febbraio MA , Lambert DL , Starkie RL , Proietto J & Hargreaves M ( 1998 ). Effect of epinephrine on muscle glycogenolysis during exercise in trained men . J Appl Physiol 84 , 465 – 470 . 

  15. Hagerty P , Lee A , Calve S , Lee CA , Vidal M & Baar K ( 2012 ). The effect of growth factors on both collagen synthesis and tensile strength of engineered human ligaments . Biomaterials 33 , 6355 – 6361 . 

  16. Heinemeier K , Langberg H & Kjaer M ( 2003 ). Exercise‐induced changes in circulating levels of transforming growth factor‐β‐1 in humans: methodological considerations . Eur J Appl Physiol 90 , 171 – 177 . 

  17. Jones JI & Clemmons DR ( 1995 ). Insulin‐like growth factors and their binding proteins: biological actions . Endocr Rev 16 , 3 – 34 . 

  18. Kapacee Z , Richardson SH , Lu Y , Starborg T , Holmes DF , Baar K & Kadler KE ( 2008 ). Tension is required for fibripositor formation . Matrix Biol 27 , 371 – 375 . 

  19. Kjaer M , Secher NH , Bach FW & Galbo H ( 1987 ). Role of motor center activity for hormonal changes and substrate mobilization in humans . Am J Physiol Regul Integr Comp Physiol 253 , R687 – 695 . 

  20. Kraemer WJ , Aguilera BA , Terada M , Newton RU , Lynch JM , Rosendaal G , McBride JM , Gordon SE & Hakkinen K ( 1995 ). Responses of IGF‐I to endogenous increases in growth hormone after heavy‐resistance exercise . J Appl Physiol 79 , 1310 – 1315 . 

  21. Kraemer WJ , Dunn‐Lewis C , Comstock BA , Thomas GA , Clark JE & Nindl BC ( 2010 ). Growth hormone, exercise, and athletic performance: a continued evolution of complexity . Curr Sports Med Rep 9 , 242 – 252 . 

  22. Kraemer WJ , Gordon SE , Fleck SJ , Marchitelli LJ , Mello R , Dziados JE , Friedl K , Harman E , Maresh C & Fry AC ( 1991 ). Endogenous anabolic hormonal and growth factor responses to heavy resistance exercise in males and females . Int J Sports Med 12 , 228 – 235 . 

  23. Kraemer WJ , Marchitelli L , Gordon SE , Harman E , Dziados JE , Mello R , Frykman P , McCurry D & Fleck SJ ( 1990 ). Hormonal and growth factor responses to heavy resistance exercise protocols . J Appl Physiol 69 , 1442 – 1450 . 

  24. Lee CA , Lee‐Barthel A , Marquino L , Sandoval N , Marcotte GR & Baar K ( 2015 ). Estrogen inhibits lysyl oxidase and decreases mechanical function in engineered ligaments . J Appl Physiol 118 , 1250 – 1257 . 

  25. Lo IKY , Marchuk LL , Hart DA & Frank CB ( 1998 ). Comparison of mRNA levels for matrix molecules in normal and disrupted human anterior cruciate ligaments using reverse transcription‐polymerase chain reaction . J Orthop Res 16 , 421 – 428 . 

  26. Louard RJ , Bhushan R , Gelfand RA , Barrett EJ & Sherwin RS ( 1994 ). Glucocorticoids antagonize insulin's antiproteolytic action on skeletal muscle in humans . J Clin Endocrinol Metab 79 , 278 – 284 . 

  27. Mackey AL , Heinemeier KM , Koskinen SO & Kjaer M ( 2008 ). Dynamic adaptation of tendon and muscle connective tissue to mechanical loading . Connect Tissue Res 49 , 165 – 168 . 

  28. Marturano JE , Xylas JF , Sridharan GV , Georgakoudi I & Kuo CK ( 2014 ). Lysyl oxidase‐mediated collagen crosslinks may be assessed as markers of functional properties of tendon tissue formation . Acta Biomater 10 , 1370 – 1379 . 

  29. Massague J ( 1998 ). TGF‐β signal transduction . Annu Rev Biochem 67 , 753 – 791 . 

  30. Moller N , Schmitz O , Porksen N , Moller J & Jorgensen JO ( 1992 ). Dose‐response studies on the metabolic effects of a growth hormone pulse in humans . Metabolism 41 , 172 – 175 . 

  31. Nindl BC , Urso ML , Pierce JR , Scofield DE , Barnes BR , Kraemer WJ , Anderson JM , Maresh CM , Beasley KN & Zambraski EJ ( 2012 ). IGF‐I measurement across blood, interstitial fluid, and muscle biocompartments following explosive, high‐power exercise . Am J Physiol Regul Integr Comp Physiol 303 , R1080 – R1089 . 

  32. Olesen JL , Heinemeier KM , Gemmer C , Kjaer M , Flyvbjerg A & Langberg H ( 2007 ). Exercise‐dependent IGF‐I, IGFBPs, and type I collagen changes in human peritendinous connective tissue determined by microdialysis . J Appl Physiol 102 , 214 – 220 . 

  33. Papakrivopoulou J , Lindahl GE , Bishop JE & Laurent GJ ( 2004 ). Differential roles of extracellular signal‐regulated kinase 1/2 and p38 MAPK in mechanical load‐induced procollagen α 1 (I) gene expression in cardiac fibroblasts . Cardiovasc Res 61 , 736 – 744 . 

  34. Paxton JZ , Donnelly K , Keatch RP & Baar K ( 2009 ). Engineering the bone‐ligament interface using polyethylene glycol diacrylate incorporated with hydroxyapatite . Tissue Eng Part A 15 , 1201 – 1209 . 

  35. Paxton JZ , Donnelly K , Keatch RP , Baar K & Grover LM ( 2010 a ). Factors affecting the longevity and strength in an in vitro model of the bone‐ligament interface . Ann Biomed Eng 38 , 2155 – 2166 . 

  36. Paxton JZ , Grover LM & Baar K ( 2010 b ). Engineering an in vitro model of a functional ligament from bone to bone . Tissue Eng Part A 16 , 3515 – 3525 . 

  37. Paxton JZ , Hagerty P , Andrick JJ & Baar K ( 2012 ). Optimizing an intermittent stretch paradigm using ERK1/2 phosphorylation results in increased collagen synthesis in engineered ligaments . Tissue Eng Part A 18 , 277 – 284 . 

  38. Redwine L , Hauger RL , Gillin JC & Irwin M ( 2000 ). Effects of sleep and sleep deprivation on interleukin‐6, growth hormone, cortisol, and melatonin levels in humans . J Clin Endocrinol Metab 85 , 3597 – 3603 . 

  39. Sakharova AA , Horowitz JF , Surya S , Goldenberg N , Harber MP , Symons K & Barkan A ( 2008 ). Role of growth hormone in regulating lipolysis, proteolysis, and hepatic glucose production during fasting . J Clin Endocrinol Metab 93 , 2755 – 2759 . 

  40. Schroeder ET , Villanueva M , West DD & Phillips SM ( 2013 ). Are acute post‐resistance exercise increases in testosterone, growth hormone, and IGF‐1 necessary to stimulate skeletal muscle anabolism and hypertrophy? Med Sci Sports Exerc 45 , 2044 – 2051 . 

  41. Sengupta S , Peterson TR & Sabatini DM ( 2010 ). Regulation of the mTOR complex 1 pathway by nutrients, growth factors, and stress . Mol Cell 40 , 310 – 322 . 

  42. Shegogue D & Trojanowska M ( 2004 ). Mammalian target of rapamycin positively regulates collagen type I production via a phosphatidylinositol 3‐kinase‐independent pathway . J Biol Chem 279 , 23166 – 23175 . 

  43. Spriet LL , Ren JM & Hultman E ( 1988 ). Epinephrine infusion enhances muscle glycogenolysis during prolonged electrical stimulation . J Appl Physiol 64 , 1439 – 1444 . 

  44. Sutton J & Lazarus L ( 1976 ). Growth hormone in exercise: comparison of physiological and pharmacological stimuli . J Appl Physiol 41 , 523 – 527 . 

  45. Vahl N , Moller N , Lauritzen T , Christiansen JS & Jorgensen JO ( 1997 ). Metabolic effects and pharmacokinetics of a growth hormone pulse in healthy adults: relation to age, sex, and body composition . J Clin Endocrinol Metab 82 , 3612 – 3618 . 

  46. Vestergaard P , Jorgensen JO , Olesen JL , Bosnjak E , Holm L , Frystyk J , Langberg H , Kjaer M & Hansen M ( 2012 ). Local administration of growth hormone stimulates tendon collagen synthesis in elderly men . J Appl Physiol 113 , 1432 – 1438 . 

  47. Weitzman ED , Zimmerman JC , Czeisler CA & Ronda J ( 1983 ). Cortisol secretion is inhibited during sleep in normal man . J Clin Endocrinol Metab 56 , 352 – 358 . 

  48. West DW , Burd NA , Tang JE , Moore DR , Staples AW , Holwerda AM , Baker SK & Phillips SM ( 2010 ). Elevations in ostensibly anabolic hormones with resistance exercise enhance neither training‐induced muscle hypertrophy nor strength of the elbow flexors . J Appl Physiol 108 , 60 – 67 . 

  49. West DW , Cotie LM , Mitchell CJ , Churchward‐Venne TA , MacDonald MJ & Phillips SM ( 2013 ). Resistance exercise order does not determine postexercise delivery of testosterone, growth hormone, and IGF‐1 to skeletal muscle . Appl Physiol Nutr Metab 38 , 220 – 226 . 

  50. West DW , Kujbida GW , Moore DR , Atherton P , Burd NA , Padzik JP , De Lisio M , Tang JE , Parise G , Rennie MJ , Baker SK & Phillips SM ( 2009 ). Resistance exercise‐induced increases in putative anabolic hormones do not enhance muscle protein synthesis or intracellular signalling in young men . J Physiol 587 , 5239 – 5247 . 

  51. Wilkinson SB , Tarnopolsky MA , Grant EJ , Correia CE & Phillips SM ( 2006 ). Hypertrophy with unilateral resistance exercise occurs without increases in endogenous anabolic hormone concentration . Eur J Appl Physiol 98 , 546 – 555 . 

관련 콘텐츠

오픈액세스(OA) 유형

BRONZE

출판사/학술단체 등이 한시적으로 특별한 프로모션 또는 일정기간 경과 후 접근을 허용하여, 출판사/학술단체 등의 사이트에서 이용 가능한 논문

이 논문과 함께 이용한 콘텐츠

섹션별 컨텐츠 바로가기

AI-Helper ※ AI-Helper는 오픈소스 모델을 사용합니다.

AI-Helper 아이콘
AI-Helper
안녕하세요, AI-Helper입니다. 좌측 "선택된 텍스트"에서 텍스트를 선택하여 요약, 번역, 용어설명을 실행하세요.
※ AI-Helper는 부적절한 답변을 할 수 있습니다.

선택된 텍스트

맨위로