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NTIS 바로가기Scientific reports, v.5, 2015년, pp.18089 -
Jung, Sang-Myung (Department of Biological Engineering, Inha University , Incheon, 402-751, Korea) , Yoon, Gwang Heum (Department of Biological Engineering, Inha University , Incheon, 402-751, Korea) , Lee, Hoo Chul (Department of Biological Engineering, Inha University , Incheon, 402-751, Korea) , Jung, Moon Hee (Department of Biological Engineering, Inha University , Incheon, 402-751, Korea) , Yu, Sun Il (Department of Biological Engineering, Inha University , Incheon, 402-751, Korea) , Yeon, Seung Ju (Department of Biological Engineering, Inha University , Incheon, 402-751, Korea) , Min, Seul Ki (Department of Biological Engineering, Inha University , Incheon, 402-751, Korea) , Kwon, Yeo Seon (Department of Biological Engineering, Inha University , Incheon, 402-751, Korea) , Hwang, Jin Ha (Department of Biological Engineering, Inha University , Incheon, 402-751, Korea) , Shin, Hwa Sung (Department of Biological Eng)
Atopic dermatitis (AD) is a complex skin disease primarily characterized by psoriasis of the stratum corneum. AD drugs have usually been used in acidic and hydrophilic solvents to supply moisture and prevent lipid defects. Ceramide is a typical treatment agent to regenerate the stratum corneum and r...
Wertz P. W. et al. The composition of the ceramides from human stratum corneum and from comedones . J Invest Dermatol 84 , 410 – 412 ( 1985 ). 3158712
Di Nardo A. et al. Ceramide and cholesterol composition of the skin of patients with atopic dermatitis . Acta Derm Venereol(stockh) 78 , 27 – 30 ( 1998 ). 9498022
Imokawa G. et al. Decreased level of ceramides in stratum corneum of atopic dermatitis: an etiologic factor in atopic dry skin? J Invest Dermatol 96 , 523 – 526 ( 1991 ). 2007790
Ohnishi Y. et al. Ceramidase activity in bacterial skin flora as a possible cause of ceramide deficiency in atopic dermatitis . Clin Diagn Lab Immun 6 , 101 – 104 ( 1999 ).
Hamanaka S. et al. Human epidermal glucosylceramides are major precursors of stratum corneum ceramides . J Invest Dermatol 119 , 416 – 423 ( 2002 ). 12190865
Pillai S. et al. Ceramide potentiates, but sphingomyelin inhibits, vitamin D-induced keratinocyte differentiation: comparison between keratinocytes and HL-60 cells . Arch Dermatol Res 291 , 284 – 289 ( 1999 ). 10367711
Lamour N. F. & Chalfant C. E. Ceramide-1-phosphate: the “missing” link in eicosanoid biosynthesis and inflammation . Mol Interv 5 , 358 ( 2005 ). 16394251
Teichgräber V. et al. Ceramide accumulation mediates inflammation, cell death and infection susceptibility in cystic fibrosis . Nat Med 14 , 382 – 391 ( 2008 ). 18376404
Lew B.-L. et al. Ceramides and cell signaling molecules in psoriatic epidermis: reduced levels of ceramides, PKC-α, and JNK . J Korean Med Sci 21 , 95 – 99 ( 2006 ). 16479073
Schliemann. et al. Protective creams fail to prevent solvent‐induced cumulative skin irritation–results of a randomized double‐blind study . Contact Derm 69 , 363 – 371 ( 2013 ). 23844768
Panther D. J. et al. The Importance of Acidification in Atopic Eczema: An Underexplored Avenue for Treatment . J Clin Med 4 , 970 – 978 ( 2015 ). 26239459
Jung J. Y. et al. Clinical use of a ceramide-based moisturizer for treating dogs with atopic dermatitis . J Vet Sci 14 , 199 – 205 ( 2013 ). 23814473
Makadia H. K. & Siegel S. J. Poly lactic-co-glycolic acid (PLGA) as biodegradable controlled drug delivery carrier . Polymers 3 , 1377 – 1397 ( 2011 ). 22577513
Lü J.-M. et al. Current advances in research and clinical applications of PLGA-based nanotechnology . Expert Rev Mol Diagn 9 , 325 – 341 ( 2009 ). 19435455
Wischke C. et al. Principles of encapsulating hydrophobic drugs in PLA/PLGA microparticles . International Journal of pharmaceutics 364 , 298 – 327 ( 2008 ). 18621492
Jain R. A. et al. Controlled release of drugs from injectable in situ formed biodegradable PLGA microspheres: effect of various formulation variables . Eur J Pharm Biopharm 50 , 257 – 262 ( 2000 ). 10962236
Nikkola L. et al. Temporal control of drug release from biodegradable polymer: multicomponent diclofenac sodium releasing PLGA 80/20 rod . J Biomed Mater Res Part B Appl Biomater 89 , 518 – 526 ( 2009 ). 19003897
Allison S. D. Analysis of initial burst in PLGA microparticles . Expert Opin Drug Deliv 5 , 615 – 625 ( 2008 ). 18532918
Liu Y.-j. et al. Control of dimensional stability and degradation rate in electrospun composite scaffolds composed of poly (d, l-lactide-co-glycolide) and poly (ε-caprolactone) . Chin J Polym Sci 26 , 63 – 71 ( 2008 ).
Kean T. & Thanou M. Biodegradation, biodistribution and toxicity of chitosan . Adv Drug Delivery Rev 62 , 3 – 11 ( 2010 ).
Raphael R. et al. J. Chitosan and Chitosan Derivatives in Drug Delivery and Tissue Engineering . Adv Polym Sci 244 19 – 44 ( 2011 ).
Lee K. Y. et al. Blood compatibility and biodegradability of partially N-acylated chitosan derivatives . Biomaterials 16 , 1211 – 1216 ( 1995 ). 8589189
Chronopoulou L. et al. Chitosan-coated PLGA nanoparticles: a sustained drug release strategy for cell cultures . Colloids Surf B 103 , 310 – 317 ( 2013 ).
Wydro P. et al. Chitosan as a lipid binder: a langmuir monolayer study of chitosan-lipid interactions . Biomacromolecules 8 , 2611 – 2617 ( 2007 ). 17630796
El-hefian E. A. et al. Surface investigation of chitosan film with fatty acid monolayers . Maejo Int J Sci Tech 3 , 277 – 286 ( 2009 ).
Sahoo S. K. et al. Residual polyvinyl alcohol associated with poly (D, L-lactide-co-glycolide) nanoparticles affects their physical properties and cellular uptake . J Control Release 82 , 105 – 114 ( 2002 ). 12106981
Aryaei A. et al. Nano and micro mechanical properties of uncross-linked and cross-linked chitosan films . J Mech Behav Biomed Mater 5 , 82 – 89 ( 2012 ). 22100082
Guo C. & Gemeinhart R. A. Understanding the adsorption mechanism of chitosan onto poly (lactide-co-glycolide) particles . Eur J Pharm Biopharm 70 , 597 – 604 ( 2008 ). 18602994
Haring M. M. Colloid and Capillary Chemistry (Freundlich, Herbert) . J Chem Educ 3 , 1454 ( 1926 ).
Knor T. et al. Stratum corneum hydration and skin surface pH in patients with atopic dermatitis . Acta Dermatovenerol Croat: ADC 19 , 242 – 247 ( 2010 ).
Mattson S. Cataphoresis and the Electrical Neutralization of Colloidal Material . J Phys Chem 32 , 1532 – 1552 ( 1928 ).
Williams A. C. & Barry B. W. Penetration enhancers . Adv Drug Deliv Rev. 64 , 128 – 137 ( 2012 ).
Kowalzick L. Novel topical therapy for mild-to-moderate plaque psoriasis: focus on calcitriol . Clin Cosmet Investig Dermatol: CCID 2 , 153 ( 2009 ).
O’Regan G. M. & Alan D. I. The role of filaggrin loss-of-function mutations in atopic dermatitis . Curr Opin Allergy Clin Immunol 8.5 , 406 – 410 ( 2008 ). 18769192
Xia M. & Sui Z. Recent developments in CCR2 antagonists . Expert Opin Ther Pat. 19 , 295 – 303 ( 2009 ) 19441905
Langmuir I. The constitution and fundamental properties of solids and liquids. part i. solids . J Am Chem Soc 38 , 2221 – 2295 ( 1916 ).
Brunauer S. et al. Adsorption of gases in multimolecular layers . J Am Chem Soc 60 , 309 – 319 ( 1938 ).
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