[논문]Ethylhexylglycerin: a low‐risk, but highly relevant, sensitizer in ‘hypo‐allergenic’ cosmetics

Aerts, Olivier; Verhulst, Lien; Goossens, An

doi:10.1111/cod.12546

Ethylhexylglycerin: a low‐risk, but highly relevant, sensitizer in ‘hypo‐allergenic’ cosmetics

Contact dermatitis, v.74 no.5, 2016년, pp.281 - 288

Aerts, Olivier (Department of Dermatology, Antwerp University Hospital (UZA) and University of Antwerp (UA), 2650, Antwerp, Belgium) , Verhulst, Lien (Department of Dermatology, University Hospitals K.U. Leuven, 3000, Leuven, Belgium) , Goossens, An (Department of Dermatology, University Hospitals K.U. Leuven, 3000, Leuven, Belgium)

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SummaryBackgroundEthylhexylglycerin is a relatively new cosmetic ingredient that is used for its surfactant, emollient, skin‐conditioning and antimicrobial properties. Since 2002, it has been occasionally reported as a contact allergen.ObjectivesTo report on 13 patients who presented with allergic contact dermatitis caused by ethylhexylglycerin, evaluated at two Belgian university patch test clinics during the period 1990–2015.Patients and methodsThe patients were patch tested with the European baseline series, a cosmetic series, and – if indicated – additional series. Both the cosmetic products used and their single ingredients were patch tested.ResultsAll but one of the ethylhexylglycerin‐allergic patients were female, with a median age of 43 years (range: 29–81 years), most often suffering from dermatitis on the face, and sometimes on the hands and/or axillae. As the culprit products, leave‐on cosmetics were identified, including a high number of proclaimed ‘hypo‐allergenic’ and ‘preservative‐free’ facial creams, sun protection creams, and deodorants.ConclusionsEthylhexylglycerin is a rare, but highly relevant, cosmetic sensitizer, even in those products advertised to be safe for consumers. Targeted patch testing with ethylhexylglycerin 5% pet. is very useful, and routine patch testing in a cosmetic series may be considered. Higher test concentrations might be indicated in selected cases.

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참고문헌 (14)

Johnson W , Bergfeld W F , Belsito D V et al. Safety assessment of alkyl glyceryl ethers as used in cosmetics . Int J Toxicol 2013 : 32 (Suppl. 3): 5S – 21S .
Linsen G , Goossens A . Allergic contact dermatitis from ethylhexylglycerin . Contact Dermatitis 2002 : 47 : 169 .

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Stausbøl‐Grøn B , Andersen K E . Allergic contact dermatitis to ethylhexylglycerin in a cream . Contact Dermatitis 2007 : 57 : 193 – 194 .

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Mortz C G , Otkjaer A , Andersen K E . Allergic contact dermatitis to ethylhexylglycerin and pentylene glycol . Contact Dermatitis 2009 : 61 : 180 .

상세보기
Dorschner R A , Shaw D W . Allergic contact dermatitis from ethylhexylglycerin . Dermatitis 2012 : 23 : 134 .
Andersen K E . Ethylhexylglycerin – a contact allergen in cosmetic products . Dermatitis 2012 : 23 : 291 .

상세보기
Sasseville D , Stanciu M . Allergic contact dermatitis from ethylhexylglycerin in sunprotectors . Dermatitis 2014 : 25 : 42 – 43 .
Johansen J D , Aalto‐Korte K , Agner T et al. European Society of Contact Dermatitis guideline for diagnostic patch testing – recommendations on best practice . Contact Dermatitis 2015 : 73 : 195 – 221 .

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Leysen J , Goossens A , Lambert J et al. Polyhexamethylene biguanide is a relevant sensitizer in wet wipes . Contact Dermatitis 2014 : 70 : 323 – 325 .

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Gaonkar T A , Geraldo I , Shintre M , Modak S M . In vivo efficacy of an alcohol‐based surgical hand disinfectant containing a synergistic combination of ethylhexylglycerin and preservatives . J Hosp Infect 2006 : 63 : 412 – 417 .

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McFadden J P , Mann J , White J M L et al. Outbreak of methylisothiazolinone allergy targeting those aged > 40 years . Contact Dermatitis 2013 : 69 : 53 – 63 .

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Aerts O , Baeck M , Constandt L et al. The dramatic increase in the rate of methylisothiazolinone contact allergy in Belgium: a multicentre study . Contact Dermatitis 2014 : 71 : 41 – 48 .

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Amaro C , Santos R , Cardoso J . Contact allergy to methylisothiazolinone in a deodorant . Contact Dermatitis 2011 : 64 : 298 – 299 .

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Vigan M . Poussée réactionnelle et tests cutanés . In: Progrès en Dermato‐Allergologie, Montpellier 2011 : Paris , John Libbey Eurotext , 2011 : pp. 165 – 175 .

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Ethylhexylglycerin: a low‐risk, but highly relevant, sensitizer in ‘hypo‐allergenic’ cosmetics

Abstract ▼ AI-Helper

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참고문헌 (14)

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