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Phentermine induces conditioned rewarding effects via activation of the PI3K/Akt signaling pathway in the nucleus accumbens

Psychopharmacology, v.233 no.8, 2016년, pp.1405 - 1413  

Hong, Sa-Ik ,  Kim, Min-Jung ,  You, In-Jee ,  Kwon, Seung-Hwan ,  Ma, Shi-Xun ,  Hwang, Ji-Young ,  Seo, Jee-Yeon ,  Ko, Yong-Hyun ,  Lee, Bo Ram ,  Lee, Seok-Yong ,  Jang, Choon-Gon

Abstract AI-Helper 아이콘AI-Helper

Phentermine is structurally similar to methamphetamine and is widely used as an anti-obesity drug in the USA and many other countries. The potential for reward of phentermine has been noted; however, the mechanisms of phentermine dependence have not been established. Here, we investigated the reward...

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