[논문]Dental implant surgery in patients in treatment with the anticoagulant oral rivaroxaban

Gó; mez‐; Moreno, Gerardo; Aguilar‐; Salvatierra, Antonio; Ferná; ndez‐; Cejas, Esther; Delgado‐; Ruiz, Rafael Arcesio; Markovic, Aleksa; Calvo‐; Guirado, José; Luis

doi:10.1111/clr.12653

Dental implant surgery in patients in treatment with the anticoagulant oral rivaroxaban

Clinical oral implants research, v.27 no.6, 2016년, pp.730 - 733

Gómez‐Moreno, Gerardo (Department of Special Care in Dentistry, Pharmacological Research in Dentistry, Director of Master in Periodontology and Implant Dentistry, Faculty of Dentistry, University of Granada, Granada, Spain) , Aguilar‐Salvatierra, Antonio (Department of Pharmacological Research in Dentistry, Faculty of Dentistry, University of Granada, Granada, Spain) , Fernández‐Cejas, Esther (Department of Pharmacological Research in Dentistry Group, Faculty of Dentistry, University of Granada, Granada, Spain) , Delgado‐Ruiz, Rafael Arcesio (School of Dental Medicine, Stony Brook University, Stony Brook, NY, USA) , Markovic, Aleksa (Department of Clinic of Oral Surgery, Faculty of Stomatology, University of Belgrade, Belgrade, Serbia) , Calvo‐Guirado, José (International Research Cathedra UCAM, Universidad Cató) , Luis (lica San Antonio, Murcia, Spain)

Abstract ▼ AI-Helper

AbstractObjectivesThe aim of this study was to evaluate the incidence of bleeding complications after dental implant placement in patients in treatment by the anticoagulant oral rivaroxaban without interrupting its administration or modifying dosage.Materials and methodsAbout 57 patients were divided into two groups: 18 had been in treatment by rivaroxaban for over 6 month before implant surgery and a control group consisted of 39 healthy subjects. All subjects received dental implants in different positions, without interrupting or modifying rivaroxaban dosage. Patients were treated in an outpatient setting. Non‐absorbable sutures were used, and all patients were given gauze impregnated with tranexamic acid 5%, to bite on for 30–60 min.ResultsOne rivaroxaban patient presented moderate bleeding the day after surgery, and two control patients presented moderate bleeding the day after and on the second day. Bleeding was managed with gauzes impregnated with tranexamic acid. No statistically significant differences (P = 0.688) were found in relation to bleeding episodes between the groups, with a relative risk = 0.919 based on the pooled groups and 95% confidence interval of 0.078–10.844.ConclusionsDental implant surgery in patients taking the anticoagulant oral rivaroxaban can be performed safely in outpatients departments applying local hemostatic measures without the need to modify or interrupt anticoagulant medication.

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참고문헌 (16)

Bacci , C. , Berengo , M. , Favero , L. & Zanon , E. ( 2011 ) Safety of dental implant surgery in patients undergoing anticoagulation therapy: a prospective case‐control study . Clinical Oral Implants Research 22 : 151 – 156 .

상세보기
Castellone , D.D. & Van Cott , E.M. ( 2010 ) Laboratory monitoring of new anticoagulants . American Journal of Hematology 85 : 185 – 187 .

상세보기
Eriksson , B.I. , Borris , L.C. , Friedman , R.J. , Haas , S. , Huisman , M.V. , Kakkar , A.K. , Bandel , T.J. , Beckmann , H. , Muehlhofer , E. , Misselwitz , F. & Geerts , W. & RECORD1 Study Group . ( 2008 ) Rivaroxaban versus enoxaparin for thromboprophylaxis after hip arthroplasty . The New England Journal of Medicine 358 : 2765 – 2775 .

상세보기
Fakhri , H.R. , Janket , S.J. , Jackson , E.A. , Baird , A.E. , Dinnocenzo , R. & Meurman , J.H. ( 2013 ) Tutorial in oral antithrombotic therapy: biology and dental implications . Medicina Oral Patologia Oral y Cirugia Bucal 18 : e461 – e472 .
Ferrieri , G.B. , Castiglioni , S. , Carmagnola , D. , Cargnel , M. , Strohmenger , L. & Abati , S. ( 2007 ) Oral surgery in patients on anticoagulant treatment without therapy interruption . Journal of Oral and Maxillofacial Surgery 65 : 1149 – 1154 .

상세보기
Firriolo , F.J. & Hupp , W.S. ( 2012 ) Beyond warfarin: the new generation of oral anticoagulants and？their implications for the management of dental patients . Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology 113 : 431 – 441 .

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Gómez‐Moreno , G. , Aguilar‐Salvatierra , A. , Martín‐Piedra , M.A. , Guardia , J. , Calvo‐Guirado , J.L. , Cabrera , M. , López‐Gallardo , C. & Castillo , T. ( 2010 ) Dabigatran and rivaroxaban, new oral anticoagulants. New approaches in dentistry . Journal of Clinical and Experimental Dentistry 2 : e14 – e18 .
Gómez‐Moreno , G. , Cutando‐Soriano , A. , Arana , C. & Scully , C. ( 2005 ) Hereditary blood coagulation disorders: management and dental treatment . Journal of Dental Research 84 : 978 – 985 .

상세보기
Kakkar , A.K. , Brenner , B. , Dahl , O.E. , Eriksson , B.I. , Mouret , P. , Muntz , J. , Soglian , A.G. , Pap , A.F. , Misselwitz , F. , Haas , S. & RECORD2 Investigators . ( 2008 ) Extended duration rivaroxaban versus short‐term enoxaparin for the prevention of venous thromboembolism after total hip arthroplasty: a double‐blind, randomised controlled trial . Lancet 372 : 31 – 39 .
Lassen , M.R. , Ageno , W. , Borris , L.C. , Lieberman , J.R. , Rosencher , N. , Bandel , T.J. , Misselwitz , F. , Turpie , A.G. & RECORD3 Investigators . ( 2008 ) Rivaroxaban versus enoxaparin for thromboprophylaxis after total knee arthroplasty . The New England Journal of Medicine 358 : 2776 – 2786 .

상세보기
Madrid , C. & Sanz , M. ( 2009 ) What influence do anticoagulants have on oral implant therapy? A systematic review . Clinical Oral Implants Research 20 : 96 – 106 .

상세보기
Mingarro‐de‐León , A. , Chaveli‐López , B. & Gavaldá‐Esteve , C. ( 2014 ) Dental management of patients receiving anticoagulant and/or antiplatelet treatment . Journal of Clinical and Experimental Dentistry 6 : e155 – e161 .
Nkenke , E. , Eitner , S. , Radespiel‐Tröger , M. , Vairaktaris , E. , Neukam , F.W. & Fenner , M. ( 2007 ) Patient‐centred outcomes comparing transmucosal implant placement with an open approach in the maxilla: a prospective, non‐randomized pilot study . Clinical Oral Implants Research 18 : 197 – 203 .

상세보기
Ramström , G. , Sindet‐Pedersen , S. , Hall , G. , Blombäck , M. & Alander , U. ( 1993 ) Prevention of postsurgical bleeding in oral surgery using tranexamic acid without dose modification of oral anticoagulants . Journal of Oral and Maxillofacial Surgery 51 : 1211 – 1216 .

상세보기
Rodríguez‐Cabrera , M.A. , Barona‐Dorado , C. , Leco‐Berrocal , I. , Gómez‐Moreno , G. & Martínez‐González , J.M. ( 2011 ) Extractions without eliminating anticoagulant treatment: a literature review . Medicina Oral Patologia Oral y Cirugia Bucal 16 : e800 – e804 .
Spyropoulos , A.C. & Douketis , J.D. ( 2002 ) How I treat anticoagulated patients undergoing an elective procedure or surgery . Blood 120 : 2954 – 2962 .

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Dental implant surgery in patients in treatment with the anticoagulant oral rivaroxaban

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