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Reduction of Adipose Tissue Mass by the Angiogenesis Inhibitor ALS-L1023 from Melissa officinalis 원문보기

PloS one, v.10 no.11, 2015년, pp.e0141612 -   

Park, Byung Young (Department of Biological Sciences, Korea Advanced Institute of Science and Technology (KAIST), Daejeon, Korea) ,  Lee, Hyunghee (Department of Biomedical Engineering, Mokwon University, Daejeon, Korea) ,  Woo, Sangee (Department of Biomedical Engineering, Mokwon University, Daejeon, Korea) ,  Yoon, Miso (Department of Biomedical Engineering, Mokwon University, Daejeon, Korea) ,  Kim, Jeongjun (Department of Biomedical Engineering, Mokwon University, Daejeon, Korea) ,  Hong, Yeonhee (Department of Biomedical Engineering, Mokwon University, Daejeon, Korea) ,  Lee, Hee Suk (AngioLab, Inc., Daejeon, Korea) ,  Park, Eun Kyu (AngioLab, Inc., Daejeon, Korea) ,  Hahm, Jong Cheon (AngioLab, Inc., Daejeon, Korea) ,  Kim, Jin Woo (Department of Biological Sciences, Korea Advanced Institute of Science and Technology (KAIST), Daejeon, Korea) ,  Shin, Soon Shik (Department of Formula Sciences, College of Oriental Medicine, Dongeui University, Busan, Korea) ,  Kim, Min-Young (AngioLab, Inc., Daejeon, Korea) ,  Yoon, Michung (Department of Biomedical Engineering, Mokwon University, Daejeon, Korea)

Abstract ▼ AI-Helper 아이콘AI-Helper

It has been suggested that angiogenesis modulates adipogenesis and obesity. This study was undertaken to determine whether ALS-L1023 (ALS) prepared by a two-step organic solvent fractionation from Melissa leaves, which exhibits antiangiogenic activity, can regulate adipose tissue growth. The effects...

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