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Alkaline phosphatase-fused repebody as a new format of immuno-reagent for an immunoassay

Analytica chimica acta : an international journal devoted to all branches of analytical chemistry, v.950, 2017년, pp.184 - 191  

Seo, Hyo-Deok (Department of Biological Sciences, Korea Advanced Institute of Science and Technology (KAIST), 291 Daehak-ro, Yuseong-gu, Daejeon, 305-701, Republic of Korea) ,  Lee, Joong-jae (Department of Biological Sciences, Korea Advanced Institute of Science and Technology (KAIST), 291 Daehak-ro, Yuseong-gu, Daejeon, 305-701, Republic of Korea) ,  Kim, Yu Jung (Industrial Biotechnology and Bioenergy Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Daejeon, Republic of Korea) ,  Hantschel, Oliver (School of Life Sciences, É) ,  Lee, Seung-Goo (cole Polytechnique Fé) ,  Kim, Hak-Sung (dé)

Abstract AI-Helper 아이콘AI-Helper

Enzyme-linked immunoassays based on an antibody-antigen interaction are widely used in biological and medical sciences. However, the conjugation of an enzyme to antibodies needs an additional chemical process, usually resulting in randomly cross-linked molecules and a loss of the binding affinity an...

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