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NTIS 바로가기Stem cell reports, v.5 no.5, 2015년, pp.791 - 804
Goldberg, Natalie R.S. (Department of Neurobiology and Behavior, University of California, Irvine, Irvine, CA 92697, USA) , Caesar, Jacqueline (Sue & Bill Gross Stem Cell Research Center, University of California, Irvine, Irvine, CA 92697, USA) , Park, Ashley (Sue & Bill Gross Stem Cell Research Center, University of California, Irvine, Irvine, CA 92697, USA) , Sedgh, Shawn (Sue & Bill Gross Stem Cell Research Center, University of California, Irvine, Irvine, CA 92697, USA) , Finogenov, Gilana (Sue & Bill Gross Stem Cell Research Center, University of California, Irvine, Irvine, CA 92697, USA) , Masliah, Eliezer (Department of Pathology and Medicine, University of California, San Diego, San Diego, CA 92093, USA) , Davis, Joy (Sue & Bill Gross Stem Cell Research Center, University of California, Irvine, Irvine, CA 92697, USA) , Blurton-Jones, Mathew (Department of Neurobiology and Behavior, University of California, Irvine, Irvine, CA 92697, USA)
SummaryAccumulation of α-synuclein (α-syn) into insoluble aggregates occurs in several related disorders collectively referred to as synucleinopathies. To date, studies have used neural stem cells (NSCs) to examine questions about α-syn propagation, but have overlooked the therapeu...
Aarts E. Nusselein A.A. Smittenaar P. Helmich R.C. Bloem B.R. Cools R. Greater striatal responses to medication in Parkinson's disease are associated with better task-switching but worse reward performance Neuropsychologia 62 2014 390 397 24912070
Albin R.L. Young A.B. Penney J.B. The functional anatomy of disorders of the basal ganglia Trends Neurosci. 18 1995 63 64 7537410
Amschl D. Neddens J. Havas D. Flunkert S. Rabl R. Römer H. Rockenstein E. Masliah E. Windisch M. Hutter-Paier B. Time course and progression of wild type α-synuclein accumulation in a transgenic mouse model BMC Neurosci. 14 2013 6 23302418
Bambah-Mukku D. Travaglia A. Chen D.Y. Pollonini G. Alberini C.M. A positive autoregulatory BDNF feedback loop via C/EBPβ mediates hippocampal memory consolidation J. Neurosci. 34 2014 12547 12559 25209292
Blurton-Jones M. Kitazawa M. Martinez-Coria H. Castello N.A. Müller F.J. Loring J.F. Yamasaki T.R. Poon W.W. Green K.N. LaFerla F.M. Neural stem cells improve cognition via BDNF in a transgenic model of Alzheimer disease Proc. Natl. Acad. Sci. USA 106 2009 13594 13599 19633196
Bonelli S.B. Ransmayr G. Steffelbauer M. Lukas T. Lampl C. Deibl M. L-dopa responsiveness in dementia with Lewy bodies, Parkinson disease with and without dementia Neurology 63 2004 376 378 15277644
Bosse K.E. Maina F.K. Birbeck J.A. France M.M. Roberts J.J. Colombo M.L. Mathews T.A. Aberrant striatal dopamine transmitter dynamics in brain-derived neurotrophic factor-deficient mice J. Neurochem. 120 2012 385 395 21988371
Canossa M. Griesbeck O. Berninger B. Campana G. Kolbeck R. Thoenen H. Neurotrophin release by neurotrophins: implications for activity-dependent neuronal plasticity Proc. Natl. Acad. Sci. USA 94 1997 13279 13286 9371837
Colloby S.J. McParland S. O’Brien J.T. Attems J. Neuropathological correlates of dopaminergic imaging in Alzheimer’s disease and Lewy body dementias Brain 135 2012 2798 2808 22961551
Desplats P. Lee H.J. Bae E.J. Patrick C. Rockenstein E. Crews L. Spencer B. Masliah E. Lee S.J. Inclusion formation and neuronal cell death through neuron-to-neuron transmission of alpha-synuclein Proc. Natl. Acad. Sci. USA 106 2009 13010 13015 19651612
Docherty M.J. Burn D.J. Parkinson’s disease dementia Curr. Neurol. Neurosci. Rep. 10 2010 292 298 20428976
Dubois B. Pillon B. Cognitive deficits in Parkinson’s disease J. Neurol. 244 1997 2 8 9007738
Ferenz K.B. Gast R.E. Rose K. Finger I.E. Hasche A. Krieglstein J. Nerve growth factor and brain-derived neurotrophic factor but not granulocyte colony-stimulating factor, nimodipine and dizocilpine, require ATP for neuroprotective activity after oxygen-glucose deprivation of primary neurons Brain Res. 1448 2012 20 26 22386494
Fernagut P.O. Hutson C.B. Fleming S.M. Tetreaut N.A. Salcedo J. Masliah E. Chesselet M.F. Behavioral and histopathological consequences of paraquat intoxication in mice: effects of alpha-synuclein over-expression Synapse 61 2007 991 1001 17879265
Gottmann K. Mittmann T. Lessmann V. BDNF signaling in the formation, maturation and plasticity of glutamatergic and GABAergic synapses Exp. Brain Res. 199 2009 203 234 19777221
Granseth B. Andersson F.K. Lindström S.H. The initial stage of reversal learning is impaired in mice hemizygous for the vesicular glutamate transporter (VGluT1) Genes Brain Behav. 14 2015 477 485 26113146
Greenamyre J.T. Glutamate-dopamine interactions in the basal ganglia: relationship to Parkinson’s disease J. Neural Transm. 91 1993 255 269
Halliday G.M. Leverenz J.B. Schneider J.S. Adler C.H. The neurobiological basis of cognitive impairment in Parkinson’s disease Mov. Disord. 29 2014 634 650 24757112
Hansen C. Angot E. Bergström A.L. Steiner J.A. Pieri L. Paul G. Outeiro T.F. Melki R. Kallunki P. Fog K. α-Synuclein propagates from mouse brain to grafted dopaminergic neurons and seeds aggregation in cultured human cells J. Clin. Invest. 121 2011 715 725 21245577
Herrera D.G. Garcia-Verdugo J.M. Alvarez-Buylla A. Adult-derived neural precursors transplanted into multiple regions in the adult brain Ann. Neurol. 46 1999 867 877 10589539
Hsu C.Y. Hung C.S. Chang H.M. Liao W.C. Ho S.C. Ho Y.J. Ceftriaxone prevents and reverses behavioral and neuronal deficits in an MPTP-induced animal model of Parkinson’s disease dementia Neuropharmacology 91 2015 43 56 25499022
Hyman C. Juhasz M. Jackson C. Wright P. Ip N.Y. Lindsay R.M. Overlapping and distinct actions of the neurotrophins BDNF, NT-3, and NT-4/5 on cultured dopaminergic and GABAergic neurons of the ventral mesencephalon J. Neurosci. 14 1994 335 347 8283241
Kim H.J. Jeon B.S. Paek S.H. Lee K.M. Kim J.Y. Lee J.Y. Kim H.J. Yun J.Y. Kim Y.E. Yang H.J. Ehm G. Long-term cognitive outcome of bilateral subthalamic deep brain stimulation in Parkinson’s disease J. Neurol. 261 2014 1090 1096 24687897
König S. Hasche A. Pallast S. Krieglstein J. Klumpp S. Detection of ATP-binding to growth factors J. Am. Soc. Mass Spectrom. 19 2008 91 95 18055212
Lees A.J. Smith E. Cognitive deficits in the early stages of Parkinson’s disease Brain 106 1983 257 270 6850270
Leverenz J.B. Watson G.S. Shofer J. Zabetian C.P. Zhang J. Montine T.J. Cerebrospinal fluid biomarkers and cognitive performance in non-demented patients with Parkinson’s disease Parkinsonism Relat. Disord. 17 2011 61 64 21044858
Marsh S.E. Blurton-Jones M. Examining the mechanisms that link β-amyloid and α-synuclein pathologies Alzheimers Res. Ther. 4 2012 11 22546279
Masliah E. Rockenstein E. Veinbergs I. Mallory M. Hashimoto M. Takeda A. Sagara Y. Sisk A. Mucke L. Dopaminergic loss and inclusion body formation in alpha-synuclein mice: implications for neurodegenerative disorders Science 287 2000 1265 1269 10678833
Masliah E. Rockenstein E. Mante M. Crews L. Spencer B. Adame A. Patrick C. Trejo M. Ubhi K. Rohn T.T. Passive immunization reduces behavioral and neuropathological deficits in an alpha-synuclein transgenic model of Lewy body disease PLoS ONE 6 2011 e19338 21559417
Massie A. Goursaud S. Schallier A. Vermoesen K. Meshul C.K. Hermans E. Michotte Y. Time-dependent changes in GLT-1 functioning in striatum of hemi-Parkinson rats Neurochem. Int. 57 2010 572 578 20643175
Mayo M.C. Bordelon Y. Dementia with Lewy bodies Semin. Neurol. 34 2014 182 188 24963677
McKeith I.G. Dickson D.W. Lowe J. Emre M. O’Brien J.T. Feldman H. Cummings J. Duda J.E. Lippa C. Perry E.K. Consortium on DLB Diagnosis and management of dementia with Lewy bodies: third report of the DLB Consortium Neurology 65 2005 1863 1872 16237129
Melo C.V. Mele M. Curcio M. Comprido D. Silva C.G. Duarte C.B. BDNF regulates the expression and distribution of vesicular glutamate transporters in cultured hippocampal neurons PLoS ONE 8 2013 e53793 23326507
Mizumoto H. Mizumoto K. Shatos M.A. Klassen H. Young M.J. Retinal transplantation of neural progenitor cells derived from the brain of GFP transgenic mice Vision Res. 43 2003 1699 1708 12818339
Mowla S.J. Farhadi H.F. Pareek S. Atwal J.K. Morris S.J. Seidah N.G. Murphy R.A. Biosynthesis and post-translational processing of the precursor to brain-derived neurotrophic factor J. Biol. Chem. 276 2001 12660 12666 11152678
Pita-Almenar J.D. Zou S. Colbert C.M. Eskin A. Relationship between increase in astrocytic GLT-1 glutamate transport and late-LTP Learn. Mem. 19 2012 615 626 23166293
Redmond D.E. Jr. Bjugstad K.B. Teng Y.D. Ourednik V. Ourednik J. Wakeman D.R. Parsons X.H. Gonzalez R. Blanchard B.C. Kim S.U. Behavioral improvement in a primate Parkinson’s model is associated with multiple homeostatic effects of human neural stem cells Proc. Natl. Acad. Sci. USA 104 2007 12175 12180 17586681
Robbins T.W. Cools R. Cognitive deficits in Parkinson’s disease: a cognitive neuroscience perspective Mov. Disord. 29 2014 597 607 24757109
Rockenstein E. Mallory M. Hashimoto M. Song D. Shults C.W. Lang I. Masliah E. Differential neuropathological alterations in transgenic mice expressing alpha-synuclein from the platelet-derived growth factor and Thy-1 promoters J. Neurosci. Res. 68 2002 568 578 12111846
Rodriguez-Kern A. Gegelashvili M. Schousboe A. Zhang J. Sung L. Gegelashvili G. Beta-amyloid and brain-derived neurotrophic factor, BDNF, up-regulate the expression of glutamate transporter GLT-1/EAAT2 via different signaling pathways utilizing transcription factor NF-kappaB Neurochem. Int. 43 2003 363 370 12742080
Saha A.R. Ninkina N.N. Hanger D.P. Anderton B.H. Davies A.M. Buchman V.L. Induction of neuronal death by alpha-synuclein Eur. J. Neurosci. 12 2000 3073 3077 10971650
Salvatore M.F. Davis R.W. Arnold J.C. Chotibut T. Transient striatal GLT-1 blockade increases EAAC1 expression, glutamate reuptake, and decreases tyrosine hydroxylase phosphorylation at ser(19) Exp. Neurol. 234 2012 428 436 22285253
Siuciak J.A. Boylan C. Fritsche M. Altar C.A. Lindsay R.M. BDNF increases monoaminergic activity in rat brain following intracerebroventricular or intraparenchymal administration Brain Res. 710 1996 11 20 8963648
Stewart T. Liu C. Ginghina C. Cain K.C. Auinger P. Cholerton B. Shi M. Zhang J. Parkinson Study Group DATATOP Investigators Cerebrospinal fluid α-synuclein predicts cognitive decline in Parkinson disease progression in the DATATOP cohort Am. J. Pathol. 184 2014 966 975 24625392
Vann Jones S.A. O’Brien J.T. The prevalence and incidence of dementia with Lewy bodies: a systematic review of population and clinical studies Psychol. Med. 44 2014 673 683 23521899
von Bohlen und Halbach O. Minichiello L. Unsicker K. Haploinsufficiency for trkB and trkC receptors induces cell loss and accumulation of alpha-synuclein in the substantia nigra FASEB J. 19 2005 1740 1742 16037097
Yamasaki T.R. Blurton-Jones M. Morrissette D.A. Kitazawa M. Oddo S. LaFerla F.M. Neural stem cells improve memory in an inducible mouse model of neuronal loss J. Neurosci. 27 2007 11925 11933 17978032
Yuan Y. Sun J. Zhao M. Hu J. Wang X. Du G. Chen N.H. Overexpression of alpha-synuclein down-regulates BDNF expression Cell. Mol. Neurobiol. 30 2010 939 946 20405200
Ziebell M. Andersen B.B. Pinborg L.H. Knudsen G.M. Stokholm J. Thomsen G. Karlsborg M. Høgh P. Mørk M.L. Hasselbalch S.G. Striatal dopamine transporter binding does not correlate with clinical severity in dementia with Lewy bodies J. Nucl. Med. 54 2013 1072 1076 23637201
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