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Neural Stem Cells Rescue Cognitive and Motor Dysfunction in a Transgenic Model of Dementia with Lewy Bodies through a BDNF-Dependent Mechanism 원문보기

Stem cell reports, v.5 no.5, 2015년, pp.791 - 804  

Goldberg, Natalie R.S. (Department of Neurobiology and Behavior, University of California, Irvine, Irvine, CA 92697, USA) ,  Caesar, Jacqueline (Sue & Bill Gross Stem Cell Research Center, University of California, Irvine, Irvine, CA 92697, USA) ,  Park, Ashley (Sue & Bill Gross Stem Cell Research Center, University of California, Irvine, Irvine, CA 92697, USA) ,  Sedgh, Shawn (Sue & Bill Gross Stem Cell Research Center, University of California, Irvine, Irvine, CA 92697, USA) ,  Finogenov, Gilana (Sue & Bill Gross Stem Cell Research Center, University of California, Irvine, Irvine, CA 92697, USA) ,  Masliah, Eliezer (Department of Pathology and Medicine, University of California, San Diego, San Diego, CA 92093, USA) ,  Davis, Joy (Sue & Bill Gross Stem Cell Research Center, University of California, Irvine, Irvine, CA 92697, USA) ,  Blurton-Jones, Mathew (Department of Neurobiology and Behavior, University of California, Irvine, Irvine, CA 92697, USA)

Abstract AI-Helper 아이콘AI-Helper

SummaryAccumulation of α-synuclein (α-syn) into insoluble aggregates occurs in several related disorders collectively referred to as synucleinopathies. To date, studies have used neural stem cells (NSCs) to examine questions about α-syn propagation, but have overlooked the therapeu...

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