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Vecuum: identification and filtration of false somatic variants caused by recombinant vector contamination 원문보기

Bioinformatics, v.32 no.20, 2016년, pp.3072 - 3080  

Kim, Junho (Severance Biomedical Science Institute, Brain Korea 21 PLUS Project for Medical Sciences, Yonsei University College of Medicine, Seoul 03722, South Korea) ,  Maeng, Ju Heon (Severance Biomedical Science Institute, Brain Korea 21 PLUS Project for Medical Sciences, Yonsei University College of Medicine, Seoul 03722, South Korea) ,  Lim, Jae Seok (Graduate School of Medical Science and Engineering, KAIST, Daejeon 34141, South Korea) ,  Son, Hyeonju (Severance Biomedical Science Institute, Brain Korea 21 PLUS Project for Medical Sciences, Yonsei University College of Medicine, Seoul 03722, South Korea) ,  Lee, Junehawk (Department of Convergence Technology Research, Korea Institute of Science and Technology Information, Daejeon 34141, South Korea) ,  Lee, Jeong Ho (Graduate School of Medical Science and Engineering, KAIST, Daejeon 34141, South Korea) ,  Kim, Sangwoo (Severance Biomedical Science Institute, Brain Korea 21 PLUS Project for Medical Sciences, Yonsei University College of Medicine, Seoul 03722, South Korea)

Abstract AI-Helper 아이콘AI-Helper

AbstractMotivation: Advances in sequencing technologies have remarkably lowered the detection limit of somatic variants to a low frequency. However, calling mutations at this range is still confounded by many factors including environmental contamination. Vector contamination is a continuously occur...

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