[논문]Antiviral activity of ovine interferon tau 4 against foot-and-mouth disease virus

Usharani, J.; Park, S.Y.; Cho, E.J.; Kim, C.; Ko, Y.J.; Tark, D.; Kim, S.M.; Park, J.H.; Lee, K.N.; Lee, M.H.; Lee, H.S.

doi:10.1016/j.antiviral.2017.01.018

Antiviral activity of ovine interferon tau 4 against foot-and-mouth disease virus

Antiviral research, v.143, 2017년, pp.134 - 141

Usharani, J. , Park, S.Y. , Cho, E.J. , Kim, C. , Ko, Y.J. , Tark, D. , Kim, S.M. , Park, J.H. , Lee, K.N. , Lee, M.H. , Lee, H.S.

Abstract ▼ AI-Helper

Foot-and-mouth disease (FMD) is an economically important disease in most parts of the world and new therapeutic agents are needed to protect the animals before vaccination can trigger the host immune response. Although several interferons have been used for their antiviral activities against Foot-and-mouth disease virus (FMDV), ovine interferon tau 4 (OvIFN-tau 4), with a broad-spectrum of action, cross-species antiviral activity, and lower incidence of toxicity in comparison to other type I interferons, has not yet been evaluated for this indication. This is the first study to evaluate the antiviral activity of OvIFN-tau 4 against various strains of FMDV. The effective anti-cytopathic concentration of OvIFN-tau 4 and its effectiveness pre- and post-infection with FMDV were tested in vitro in LFBK cells. In vivo activity of OvIFN-tau 4 was then confirmed in a mouse model of infection. OvIFN-tau 4 at a concentration of 500 ng, protected mice until 5days post-FMDV challenge and provided 90% protection for 10 days following FMDV challenge. These results suggest that OvIFN-tau 4 could be used as an alternative to other interferons or antiviral agents at the time of FMD outbreak. (C) 2017 Published by Elsevier B.V.

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참고문헌 (30)

J. Interferon Cytokine Res. Alexenko 19 1335 1999 10.1089/107999099312795 The cross-species antiviral activities of different IFN-tau subtypes on bovine, murine, and human cells: contradictory evidence for therapeutic potential

상세보기
Am. J. Vet. Res. Cummins 66 164 2005 10.2460/ajvr.2005.66.164 Systemic effects of interferons after oral administration in animals and humans

상세보기
J. Acquir Immune Defic. Syndr. Hum. Retrovirol. Dereuddre-Bosquet 11 241 1996 10.1097/00042560-199603010-00004 Anti-HIV potential of a new interferon, interferon-tau (trophoblastin)

상세보기
Virology Diaz-San Segundo 413 283 2011 10.1016/j.virol.2011.02.023 Antiviral activity of bovine type III interferon against foot-and-mouth disease virus

상세보기
Virus Res. Domingo 91 47 2003 10.1016/S0168-1702(02)00259-9 Evolution of foot-and-mouth disease virus

상세보기
Clin. Microbiol. Rev. Grubman 17 465 2004 10.1128/CMR.17.2.465-493.2004 Foot-and-mouth disease

상세보기
J. Interferon Cytokine Res. Johnson 19 1107 1999 10.1089/107999099313046 IFN-tau exhibits potent suppression of human papillomavirus E6/E7 oncoprotein expression

상세보기
J. Gen. Virol. Juste 81 525 2000 10.1099/0022-1317-81-2-525 Effects of recombinant ovine interferon-tau on ovine lentivirus replication and progression of disease

상세보기
Antivir. Res. Kim 104 52 2014 10.1016/j.antiviral.2014.01.014 A recombinant adenovirus bicistronically expressing porcine interferon-alpha and interferon-gamma enhances antiviral effects against foot-and-mouth disease virus

상세보기
J. Clin. Microbiol. LaRocco 51 1714 2013 10.1128/JCM.03370-12 A continuous bovine kidney cell line constitutively expressing bovine alphavbeta6 integrin has increased susceptibility to foot-and-mouth disease virus

상세보기
Methods Livak 25 402 2001 10.1006/meth.2001.1262 Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) method

상세보기
Biochimie Martal 80 755 1998 10.1016/S0300-9084(99)80029-7 IFN-tau: a novel subtype I IFN1. Structural characteristics, non-ubiquitous expression, structure-function relationships, a pregnancy hormonal embryonic signal and cross-species therapeutic potentialities

상세보기
J. Virol. Moraes 81 7124 2007 10.1128/JVI.02775-06 Enhanced antiviral activity against foot-and-mouth disease virus by a combination of type I and II porcine interferons

상세보기
J. Interferon Cytokine Res. Nakajima 22 397 2002 10.1089/107999002753675839 Induction of blood 2',5'-oligoadenylate synthetase activity in mice by gastric administration of ovine IFN-tau

상세보기
Endocrinology Oliveira 149 1252 2008 10.1210/en.2007-0863 Expression of interferon (IFN)-stimulated genes in extrauterine tissues during early pregnancy in sheep is the consequence of endocrine IFN-tau release from the uterine vein

상세보기
Biol. Reprod. Ott 57 621 1997 10.1095/biolreprod57.3.621 Effects of exogenous recombinant ovine interferon tau on circulating concentrations of progesterone, cortisol, luteinizing hormone, and antiviral activity; interestrous interval; rectal temperature; and uterine response to oxytocin in cyclic ewes

상세보기
Emerg. Infect. Dis. Park 19 655 2013 10.3201/eid1904.121320 Control of foot-and-mouth disease during 2010-2011 epidemic, South Korea

상세보기
Nat. Rev. Immunol. Platanias 5 375 2005 10.1038/nri1604 Mechanisms of type-I- and type-II-interferon-mediated signalling

상세보기
Cancer Res. Pontzer 51 5304 1991 Antiproliferative activity of a pregnancy recognition hormone, ovine trophoblast protein-1

상세보기
J. Interferon Res. Pontzer 14 133 1994 10.1089/jir.1994.14.133 Structure/function studies with interferon tau: evidence for multiple active sites

상세보기
Biochem. Biophys. Res. Commun. Pontzer 152 801 1988 10.1016/S0006-291X(88)80109-8 Antiviral activity of the pregnancy recognition hormone ovine trophoblast protein-1

상세보기
J. Immunol. Pontzer 158 4351 1997 10.4049/jimmunol.158.9.4351 Potent anti-feline immunodeficiency virus and anti-human immunodeficiency virus effect of IFN-tau

상세보기
Am. J. Hyg. Reed 27 493 1938 A simple method of estimating fifty per cent endpoints
J. Interferon Cytokine Res. Roberts 18 805 1998 10.1089/jir.1998.18.805 The evolution of the type I interferons

상세보기
J. Virol. Rogez 77 12914 2003 10.1128/JVI.77.23.12914-12920.2003 Anti-human immunodeficiency virus activity of tau interferon in human macrophages: involvement of cellular factors and beta-chemokines

상세보기
Nat. Rev. Immunol. Sadler 8 559 2008 10.1038/nri2314 Interferon-inducible antiviral effectors

상세보기
Clin. Microbiol. Rev. Samuel 14 778 2001 10.1128/CMR.14.4.778-809.2001 Antiviral actions of interferons

상세보기
Rev. Sci. Tech. Scudamore 21 699 2002 10.20506/rst.21.3.1351 Control of foot and mouth disease: lessons from the experience of the outbreak in Great Britain in 2001

상세보기
J. Immunol. Soos 155 2747 1995 10.4049/jimmunol.155.5.2747 The IFN pregnancy recognition hormone IFN-tau blocks both development and superantigen reactivation of experimental allergic encephalomyelitis without associated toxicity

상세보기
Virology Zhu 404 32 2010 10.1016/j.virol.2010.04.021 Differential gene expression in bovine cells infected with wild type and leaderless foot-and-mouth disease virus

상세보기

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Antiviral activity of ovine interferon tau 4 against foot-and-mouth disease virus

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Antiviral activity of ovine interferon tau 4 against foot-and-mouth disease virus

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