[논문]Evaluation of Medicinal Categorization of Atractylodes japonica Koidz. by Using Internal Transcribed Spacer Sequencing Analysis and HPLC Fingerprinting Combined with Statistical Tools

Kim, Jung-Hoon; Doh, Eui-Jeong; Lee, Guemsan

doi:10.1155/2016/2926819

Evaluation of Medicinal Categorization of Atractylodes japonica Koidz. by Using Internal Transcribed Spacer Sequencing Analysis and HPLC Fingerprinting Combined with Statistical Tools 원문보기

Evidence-based Complementary and Alternative Medicine : eCAM, v.2016, 2016년, pp.2926819 -

Kim, Jung-Hoon (Division of Pharmacology, School of Korean Medicine, Pusan National University, Yangsan 626-870, Republic of Korea) , Doh, Eui-Jeong (Department of Herbology, College of Korean Medicine, Wonkwang University, Iksan 570-749, Republic of Korea) , Lee, Guemsan (Department of Herbology, College of Korean Medicine, Wonkwang University, Iksan 570-749, Republic of Korea)

Abstract ▼ AI-Helper

Atractylodes rhizomes have been used as the herbal medicine “Changchul” or “Baekchul,” according to their clinical purpose, in Korea, China, and Japan. Among the Atractylodes species, the medicinal use of Atractylodes japonica has been controversial, as it is categorized as both Changchul and Baekchul in those countries, and, moreover, parts of the rhizome have been differently used, depending on age of the plant, in Korea. Chromatographic fingerprinting by using HPLC combined with chemometric analyses and internal transcribed spacer (ITS) sequencing analysis were conducted to classify and identify 34 crude drugs derived from Atractylodes rhizomes. The identification of the samples, authenticated by their morphological features as A. japonica Koidz. (Changchul and Baekchul), A. chinensis Koidz., and A. macrocephala Koidz., was confirmed as A. japonica, A. chinensis, and A. macrocephala by ITS sequencing. The results from chemometric analyses showed that the chemical components of the crude drugs from A. japonica were significantly different from those from A. macrocephala but were similar to those from A. chinensis. The analyses also suggested that the categorization by age of A. japonica as Changchul or Baekchul is not recommended. The results indicate that A. japonica should be categorized as “Changchul” and should not be further categorized by age.

참고문헌 (38)

1 Bensky D. Clavey S. Stöger E. Chinese Herbal Medicine: Materia Medica 2004 3rd Seattle, Wash, USA Eastland Press
2 The Korea Food and Drug Administration The Korean Pharmacopeia 2013 10th The Korea Food and Drug Administration
3 The Pharmacopoeia Commission of the Ministry of Health of the People's Republic of China The Pharmacopoeia of the People's Republic of China 2010 10th Beijing, China China Science and Technology Press
4 Society of Japanese Pharmacopoeia Japanese Pharmacopeia 2011 65 The Ministry of Health Labor and Welfare Ministerial Notification
5 Li J. You W. Analysis of nuclear types in chromosome of Japanese Atractylodes Journal of Shenyang Agricultural University 1987 18 75 77
6 Kang E. M. Jeong C. H. Shim K. H. Functional properties of Korean Atractylodes japonica Koidz Korean Journal of Post-Harvest Science and Technology of Agricultural Products 2001 8 86 91
7 Wu Z. Y. Flora of China 2011 20 Beijing, China Science Press
8 Park J. M. Jang K. H. Lee S. T. Growth characteristics of Atractylodes japonica Koidz. In its native habitat Korean Journal of Medicinal Crop Science 2000 8 327 333
9 Ma X. Q. Duan J. A. Zhu D. Y. Dong T. T. X. Tsim K. W. K. Species identification of Radix astragali (Huangqi) by DNA sequence of its 5S-rRNA spacer domain Phytochemistry 2000 54 4 363 368 10.1016/s0031-9422(00)00111-4 2-s2.0-0034733504 10897476

상세보기
10 Choo B. K. Moon B. C. Ji Y. Development of SCAR markers for the discrimination of three species of medicinal plants, Angelica decursiva ( Peucedanum decursivum ), Peucedanum praeruptorum and Anthricus sylvestris , based on the internal transcribed spacer (ITS) sequence and random amplified polymorphic DNA (RAPD) Biological and Pharmaceutical Bulletin 2009 32 1 24 30 10.1248/bpb.32.24 2-s2.0-59949087115 19122275

상세보기
11 Chen Y.-Q. Wang N. Qu L.-H. Li T.-H. Zhang W.-M. Determination of the anamorph of Cordyceps sinensis inferred from the analysis of the ribosomal DNA internal transcribed spacers and 5.8S rDNA Biochemical Systematics and Ecology 2001 29 6 597 607 10.1016/s0305-1978(00)00100-9 2-s2.0-0035039946 11336809

상세보기
12 Takamiya T. Wongsawad P. Tajima N. Identification of Dendrobium species used for herbal medicines based on ribosomal DNA Internal transcribed spacer sequence Biological and Pharmaceutical Bulletin 2011 34 5 779 782 10.1248/bpb.34.779 2-s2.0-79955644175 21532173

상세보기
13 Wu C.-T. Hsieh C.-C. Lin W.-C. Internal transcribed spacer sequence-based identification and phylogenic relationship of I-Tiao-Gung originating from Flemingia and Glycine (Leguminosae) in Taiwan Journal of Food and Drug Analysis 2013 21 4 356 362 10.1016/j.jfda.2013.08.002 2-s2.0-84895927947

상세보기
14 Shiba M. Kondo K. Miki E. Identification of medicinal Atractylodes based on ITS sequences of nrDNA Biological and Pharmaceutical Bulletin 2006 29 2 315 320 10.1248/bpb.29.315 2-s2.0-32044456010 16462038

상세보기
15 Kondo K. Shiba M. Yotsuyanagi Y. Nishimura N. Maruyama T. Goda Y. Discrimination between Atractylodes rhizome (Byaku-jutsu) and Atractylodes lancea rhizome (So-jutsu) by the PCR-RFLP analysis of ITS region on nrDNA nrDNA Journal of Japanese Botany 2009 84 6 356 359 2-s2.0-75749155843
16 Ge Y.-F. Hang Y.-Y. Xia B. Wei Y.-L. Sequencing of trn L-F and analysis of interspecific genetic relationship of five medicinal species in Atractylodes DC Journal of Plant Resources and Environment 2007 16 2 12 16 2-s2.0-34547614828

상세보기
17 Peng H.-S. Yuan Q.-J. Li Q.-Q. Huang L.-Q. Molecular systematics of genus atractylodes (Compositae, Cardueae): evidence from internal transcribed spacer (ITS) and trnL-F sequences International Journal of Molecular Sciences 2012 13 11 14623 14633 10.3390/ijms131114623 2-s2.0-84870717624 23203084

상세보기
18 Yang D.-Z. An Y.-Q. Jiang X.-L. Development of a novel method combining HPLC fingerprint and multi-ingredients quantitative analysis for quality evaluation of traditional Chinese medicine preparation Talanta 2011 85 2 885 890 10.1016/j.talanta.2011.04.059 2-s2.0-79959951665 21726714

상세보기
19 Kang J. Zhou L. Sun J. Han J. Guo D.-A. Chromatographic fingerprint analysis and characterization of furocoumarins in the roots of Angelica dahurica by HPLC/DAD/ESI-MS n technique Journal of Pharmaceutical and Biomedical Analysis 2008 47 4-5 778 785 10.1016/j.jpba.2008.03.010 18436412

상세보기
20 Xie B. Gong T. Tang M. An approach based on HPLC-fingerprint and chemometrics to quality consistency evaluation of Liuwei Dihuang Pills produced by different manufacturers Journal of Pharmaceutical and Biomedical Analysis 2008 48 4 1261 1266 10.1016/j.jpba.2008.09.011 2-s2.0-57849160615 18930621

상세보기
21 Xu X. Jiang J. Liang Y. Yi L. Cheng J. Chemical fingerprint analysis for quality control of Fructus aurantii immaturus based on HPLC-DAD combined with chemometric methods Analytical Methods 2010 2 12 2002 2010 10.1039/c0ay00455c 2-s2.0-78650315466

상세보기
22 Sajewicz M. Staszek D. Wróbel M. S. The HPLC/DAD fingerprints and chemometric analysis of flavonoid extracts from the selected Sage ( Salvia ) species Chromatography Research International 2012 2012 8 230903 10.1155/2012/230903

상세보기
23 Zhang Q.-F. Cheung H.-Y. Zeng L.-B. Development of HPLC fingerprint for species differentiation and quality assessment of Rhizoma Smilacis Glabrae Journal of Natural Medicines 2013 67 1 207 211 10.1007/s11418-012-0648-9 2-s2.0-84871266414 22382863

상세보기
24 Tao W. Duan J. Zhao R. Comparison of three officinal Chinese pharmacopoeia species of Glycyrrhiza based on separation and quantification of triterpene saponins and chemometrics analysis Food Chemistry 2013 141 3 1681 1689 10.1016/j.foodchem.2013.05.073 2-s2.0-84884564608 23870878

상세보기
25 Nakai Y. Yano K. Shiba M. Chemical characterization of rhizomes of Atractylodes lancea and A. chinensis identified by ITS sequences of nrDNA Journal of Japanese Botany 2006 81 2 63 74 2-s2.0-33646836443

상세보기
26 Xia Y.-G. Yang B.-Y. Wang Q.-H. Liang J. Wang D. Kuang H.-X. Species classification and quality assessment of Cangzhu (Atractylodis rhizoma) by high-performance liquid chromatography and chemometric methods Journal of Analytical Methods in Chemistry 2013 2013 7 497532 10.1155/2013/497532 2-s2.0-84881471324

상세보기
27 White T. J. Bruns T. Lee S. Taylor J. Innis M. A. Gelfand D. H. Sninsky J. J. White T. J. Amplification and direct sequencing of fungal ribosomal RNA genes for phylogenetics PCR Protocols: A Guide to Methods and Applications 1990 New York, NY, USA Academic Press 315 322
28 Garcia-Jacas N. Garnatje T. Susanna A. Vilatersana R. Tribal and subtribal delimitation and phylogeny of the cardueae (Asteraceae): a combined nuclear and chloroplast DNA analysis Molecular Phylogenetics and Evolution 2002 22 1 51 64 10.1006/mpev.2001.1038 2-s2.0-0036366236 11796029

상세보기
29 Susanna A. Garcia-Jacas N. Hidalgo O. Vilatersana R. Garnatje T. The Cardueae (Compositae) revisited: insights from ITS, trnL-trnF, and matK nuclear and chloroplast DNA analysis Annals of the Missouri Botanical Garden 2006 93 1 150 171 10.3417/0026-6493(2006)93[150:tccrif]2.0.co;2 2-s2.0-33646249707

상세보기
30 Mizukami H. Shimizu R. Kohjyouma M. Kohda H. Kawanishi F. Hiraoka N. Phylogenetic analysis of Atractylodes plants based on chloroplast trnK sequence Biological and Pharmaceutical Bulletin 1998 21 5 474 478 10.1248/bpb.21.474 2-s2.0-0031838014 9635503

상세보기
31 Guo L. P. Huang L. Q. Wang M. Feng X. F. Fu G. F. Yan Y. N. A preliminary study on relationship between Atractylodes lancea and A. chinensis as analyzed by RAPD Zhongguo Zhong Yao Za Zhi 2001 26 3 156 158 2-s2.0-0035297336 12525031

상세보기
32 Huh M. K. Bang K. H. Identification of Atractylodes japonica and A. macrocephala by RAPD analysis and SCAR markers Silvae Genetica 2006 55 3 101 105 2-s2.0-33745768825

상세보기
33 Lee D.-Y. Cho J.-G. Lee M.-K. Discrimination of Panax ginseng roots cultivated in different areas in Korea using HPLC-ELSD and principal component analysis Journal of Ginseng Research 2011 35 1 31 38 10.5142/jgr.2011.35.1.031 2-s2.0-79955604938

원문보기 상세보기
34 Kumooka Y. Hierarchical cluster analysis as a tool for preliminary discrimination of ATR-FT-IR spectra of OPP acrylic and rubber-based adhesives Forensic Science International 2009 189 1–3 104 110 10.1016/j.forsciint.2009.04.025 2-s2.0-67349195586 19481889

상세보기
35 Goodarzi M. Russell P. J. Heyden Y. V. Similarity analyses of chromatographic herbal fingerprints: a review Analytica Chimica Acta 2013 804 16 28 10.1016/j.aca.2013.09.017 2-s2.0-84888057179 24267059

상세보기
36 Zhang Z.-J. Therapeutic effects of herbal extracts and constituents in animal models of psychiatric disorders Life Sciences 2004 75 14 1659 1699 10.1016/j.lfs.2004.04.014 2-s2.0-3242741013 15268969

상세보기
37 Lu J. Wang J.-S. Kong L.-Y. Anti-inflammatory effects of Huang-Lian-Jie-Du decoction, its two fractions and four typical compounds Journal of Ethnopharmacology 2011 134 3 911 918 10.1016/j.jep.2011.01.049 2-s2.0-79954417397 21296144

상세보기
38 Tian L. Bi K.-S. Sun W.-J. Zhao S.-C. Wu G.-F. Lu Y. Chemical pattern recognition in the Rhizoma of Atractylodes macrocephala China Journal of Chinese Materia Medica 2003 28 2 143 146 2-s2.0-2942677120 15015289

상세보기

LOADING...

표제어: PCR

동의어: Packet Collision Rate

용어 설명 출처 목록 (6)

용어 설명: PCR은 세균 특이성이 있는 primer를 이용하여 적은 수의 세균이 있을지라도 쉽게 검출할 수 있는 유용한 방법이며, 이를 이용하여 구강 내 치면세균막이나 타액에서 직접 세균을 검출할 수 있게 되었다[8].

내보내기 구분	파일저장 인쇄 메일전송
구성항목	기본정보 상세정보 관리번호, 논문명, 저널/프로시딩명, 저자 , 발행년, 권, 호, 시작페이지, 끝페이지, 발행기관 관리번호, 논문명, 대등논문명, 저자 , 저널/프로시딩명, 발행기관, 발행년, 발행언어, 권, 호, 시작페이지, 끝페이지, ISBN, ISSN, 주제분야, 키워드, 초록(한글), 초록(영문), 저자(소속기관)
저장형식	Text(ASCII format) Excel format RefWorks Direct Export RIS format (for Reference Manager, ProCite, EndNote), Scholar's Aids, Mendeley
메일정보	받는사람 (필수) @ 보내는사람 (선택) @ 제목 내용 KISTI 검색결과 이메일 서비스
안내	총 건의 자료가 검색되었습니다. 다운받으실 자료의 인덱스를 입력하세요. (1-10,000) 검색결과의 순서대로 최대 10,000건 까지 다운로드가 가능합니다. 데이타가 많을 경우 속도가 느려질 수 있습니다.(최대 2~3분 소요) 다운로드 파일은 UTF-8 형태로 저장됩니다. 파일의 내용이 제대로 보이지 않을실 때는 웹브라우저 상단의 보기 -> 인코딩 -> 자동선택 여부를 확인하십시오. ~ Text(ASCII format) Excel format

연합인증

Evaluation of Medicinal Categorization of Atractylodes japonica Koidz. by Using Internal Transcribed Spacer Sequencing Analysis and HPLC Fingerprinting Combined with Statistical Tools 원문보기

Abstract ▼ AI-Helper

참고문헌 (38)

이 논문을 인용한 문헌

연구과제 타임라인

관련 콘텐츠

원문 보기

원문 URL 링크

오픈액세스(OA) 유형

이 논문과 함께 이용한 콘텐츠

AI-Helper ※ AI-Helper는 오픈소스 모델을 사용합니다.

선택된 텍스트

연합인증

Evaluation of Medicinal Categorization of Atractylodes japonica Koidz. by Using Internal Transcribed Spacer Sequencing Analysis and HPLC Fingerprinting Combined with Statistical Tools 원문보기

Abstract ▼ AI-Helper

참고문헌 (38)

이 논문을 인용한 문헌

연구과제 타임라인

전체(0) 논문(0) 특허(0) 보고서(0)

전체(0) 논문(0) 특허(0) 보고서(0)

관련 콘텐츠

원문 보기

원문 URL 링크

오픈액세스(OA) 유형

이 논문과 함께 이용한 콘텐츠

AI-Helper ※ AI-Helper는 오픈소스 모델을 사용합니다.

선택된 텍스트