최소 단어 이상 선택하여야 합니다.
최대 10 단어까지만 선택 가능합니다.
다음과 같은 기능을 한번의 로그인으로 사용 할 수 있습니다.
NTIS 바로가기Journal of medicinal food, v.19 no.3, 2016년, pp.290 - 299
Kim, Kyung Eun (Department of Anatomy and Convergence Medical Science, Institute of Health Sciences, Gyeongsang National University School of Medicine , Gyeongnam, Republic of Korea.) , Ko, Keon-Hee (Gyeongnam Oriental Medicinal Herb Institute , Gyeongnam, Republic of Korea.) , Heo, Rok Won (Department of Anatomy and Convergence Medical Science, Institute of Health Sciences, Gyeongsang National University School of Medicine , Gyeongnam, Republic of Korea.) , Yi, Chin-ok (Department of Anatomy and Convergence Medical Science, Institute of Health Sciences, Gyeongsang National University School of Medicine , Gyeongnam, Republic of Korea.) , Shin, Hyun Joo (Department of Anatomy and Convergence Medical Science, Institute of Health Sciences, Gyeongsang National University School of Medicine , Gyeongnam, Republic of Korea.) , Kim, Jun Young (Busan Regional Korea Food and Drug Administration , Ministry of Food and Drug Safety, Busan, Republic of Korea.) , Park, Jae-Ho (Shinseon F&V Co., Ltd. , Gyeongnam, Republic of Korea.) , Nam, Sanghae (Division of Food Science, Gyeongnam National University of Science and Tech) , Kim, Hwajin , Roh, Gu Seob
AbstractArtemisia annua L. (AA) is a well-known source of the antimalarial drug artemisinin. AA also has an antibacterial and antioxidant activity. However, the effect of AA extract on hepatic steatosis induced by obesity is unclear. We investigated whether AA extract prevents obesity-induced insuli...
1 Räth K , Taxis K , Walz G , Gleiter CH , Li SM , Heide L : Pharmacokinetic study of artemisinin after oral intake of a traditional preparation of Artemisia annua L . (annual wormwood) . Am J Trop Med Hyg 2004 ; 70 : 128 – 132 14993622
2 Ho WE , Peh HY , Chan TK , Wong WS : Artemisinins: Pharmacological actions beyond anti-malarial . Pharmacol Ther 2014 ; 142 : 126 – 139 24316259
3 Kim MH , Seo JY , Liu KH , Kim JS : Protective effect of Artemisia annua L. extract against galactose-induced oxidative stress in mice . PLoS One 2014 ; 9 : e101486 24988450
4 Zheng GQ : Cytotoxic terpenoids and flavonoids from Artemisia annua . Planta Med 1994 ; 60 : 54 – 57 8134418
5 Sun B , Karin M : Obesity, inflammation, and liver cancer . J Hepatol 2012 ; 56 : 704 – 713 22120206
6 Postic C , Girard J : The role of the lipogenic pathway in the development of hepatic steatosis . Diabetes Metab 2008 ; 34 : 643 – 648 19195625
7 Abelmalek MF , Diehl AM : Nonalcoholic fatty liver disease as a complication of insulin resistance . Med Clin North Am 2007 ; 91 : 1125 – 1149 17964913
8 Tu K , Zheng X , Yin G , Zan X , Yao Y , Liu Q : Evaluation of Fbxw7 expression and its correlation with expression of SREBP-1 in a mouse model of NAFLD . Mol Med Rep 2012 ; 6 : 525 – 530 22710480
9 Dentin R , Girard J , Postic C : Carbohydrate responsive element binding protein (ChREBP) and sterol regulatory element binding protein-1c (SREBP-1c): Two key regulators of glucose metabolism and lipid synthesis in liver . Biochimie 2005 ; 87 : 81 – 86 15733741
10 Filhoulaud G , Guilmeau S , Dentin R , Girard J , Postic C : Novel insights into ChREBP regulation and function . Trends Endocrinol Metab 2013 ; 24 : 257 – 268 23597489
11 Foufelle F , Ferré P : New perspectives in the regulation of hepatic glycolytic and lipogenic genes by insulin and glucose: A role for the transcription factor sterol regulatory element binding protein-1c . Biochem J 2002 ; 366 : 377 – 391 12061893
12 Kamari Y , Shaish A , Vax E , et al. : Lack of interleukin-1α or interleukin-1β inhibits transformation of steatosis to steatohepatitis and liver fibrosis in hypercholesterolemic mice . J Hepatol 2011 ; 55 : 1086 – 1094 21354232
13 Chen R , Hou W , Zhang Q , Kang R , Fan XG , Tang D : Emerging role of high-mobility group box 1 (HMGB1) in liver diseases . Mol Med 2013 ; 19 : 357 – 366 24306421
14 Chiang DJ , Pritchard MT , Nagy LE : Obesity, diabetes mellitus, and liver fibrosis . Am J Physiol Gastrointest Liver Physiol 2011 ; 300 : G697 – G702 21350183
15 Matsui T , Ueda T , Oki T , Sugita K , Terahara N , Matsumoto K : α-Glucosidase inhibitory action of natural acylated anthocyanins. 1. Survey of natural pigments with potent inhibitory activity . J Agric Food Chem 2001 ; 49 : 1948 – 1951 11308351
16 Jeon BT , Heo RW , Shin HJ , et al. : Attenuation by a Vigna nakashimae extract of nonalcoholic fatty liver disease in high-fat diet-fed mice . Biosci Biotechnol Biochem 2014 ; 78 : 482 – 489 25036839
17 Alexei L , Eba A , Benhilda NM , et al. : Integrating medicinal plants extraction into a high-value biorefinery: An example of Artemisia annua L . C R Chim 2014 ; 17 : 232 – 241
19 Huang GJ , Hsieh WT , Chang HY , Huang SS , Lin YC , Kuo YH : α-Glucosidase and aldose reductase inhibitory activities from the fruiting body of Phellinus merrillii . J Agric Food Chem 2011 ; 59 : 5702 – 5706 21452825
20 Kumar S , Narwal S , Kumar V , Prakash O : α-Glucosidase inhibitors from plants: A natural approach to treat diabetes . Pharmacogn Rev 2011 ; 5 : 19 – 29 22096315
21 Willcox ML , Burton S , Oyweka R , Namyalo R , Challand S , Lindsey K : Evaluation and pharmacovigilance of projects promoting cultivation and local use of Artemisia annua for malaria . Malar J 2011 ; 10 : 84 21481234
22 Wellen KE , Hotamisligil GS : Inflammation, stress, and diabetes . J Clin Invest 2005 ; 115 : 1111 – 1119 15864338
23 Liu IM , Tzeng TF , Liou SS , Lan TW : Improvement of insulin sensitivity in obese Zucker rats by myricetin extracted from Abelmoschus moschatus . Planta Med 2007 ; 73 : 1054 – 1060 17694473
24 Chang CJ , Tzeng TF , Liou SS , Chang YS , Liu IM : Myricetin increases hepatic peroxisome proliferator-activated receptor α protein expression and decreases plasma lipids and adiposity in rats . Evid Based Complement Alternat Med 2012 ; 2012 : 787152 22474525
25 Sakurai M , Takamura T , Ota T , et al. : Liver steatosis, but not fibrosis, is associated with insulin resistance in nonalcoholic fatty liver disease . J Gastroenterol 2007 ; 42 : 312 – 317 17464461
26 Ferré P , Foufelle F : Hepatic steatosis: A role for de novo lipogenesis and the transcription factor SREBP-1c . Diabetes Obes Metab 2010 ; 12 : 83 – 92 21029304
27 Iizuka K , Bruick RK , Liang G , Horton JD , Uyeda K : Deficiency of carbohydrate response element-binding protein (ChREBP) reduces lipogenesis as well as glycolysis . Proc Natl Acad Sci USA 2004 ; 101 : 7281 – 7286 15118080
28 Tsatsos NG , Davies MN , O'Callaghan BL , Towle HC : Identification and function of phosphorylation in the glucose-regulated transcription factor ChREBP . Biochem J 2008 ; 411 : 261 – 270 18215143
29 Dentin R , Benhamed F , Hainaylt , et al. : Liver-specific inhibition of ChREBP improves hepatic steatosis and insulin resistance in ob/ob mice . Diabetes 2006 ; 55 : 2159 – 2170 16873678
30 Iizuka K , Miller B , Uyeda K : Deficiency of carbohydrate-activated transcription factor ChREBP prevents obesity and improves plasma glucose control in leptin-deficient (ob/ob) mice . Am J Physiol Endocrinol Metab 2006 ; 291 : E358 – E364 16705063
31 Benhamed F , Denechaud PD , Lemoine M , et al. : The lipogenic transcription factor ChREBP dissociates hepatic steatosis from insulin resistance in mice and humans . J Clin Invest 2012 ; 122 : 2176 – 2194 22546860
32 Ge WS , Wu JX , Fan JG , Wang YJ , Chen YW : Inhibition of high-mobility group box 1 expression by siRNA in rat hepatic stellate cells . World J. Gastroenterol 2011 ; 17 : 4090 – 4098 22039322
33 Chen J , Liu D , Bai Q , et al. : Celecoxib attenuates liver steatosis and inflammation in non-alcoholic steatohepatitis induced by high-fat diet in rats . Mol Med Rep 2011 ; 4 : 811 – 816 21643627
34 Hsieh PS , Jin JS , Chiang CF , Chan PC , Chen CH , Shih KC : COX-2-mediated inflammation in fat is crucial for obesity-linked insulin resistance and fatty liver . Obesity (Silver Spring) 2009 ; 17 : 1150 – 1157 19247274
35 Lipson KE , Wong C , Teng Y , Spong S : CTGF is a central mediator of tissue remodeling and fibrosis and its inhibition can reverse the process of fibrosis . Fibrogenesis Tissue Repair 2012 ; 5 : S24 23259531
※ AI-Helper는 부적절한 답변을 할 수 있습니다.