$\require{mediawiki-texvc}$

연합인증

연합인증 가입 기관의 연구자들은 소속기관의 인증정보(ID와 암호)를 이용해 다른 대학, 연구기관, 서비스 공급자의 다양한 온라인 자원과 연구 데이터를 이용할 수 있습니다.

이는 여행자가 자국에서 발행 받은 여권으로 세계 각국을 자유롭게 여행할 수 있는 것과 같습니다.

연합인증으로 이용이 가능한 서비스는 NTIS, DataON, Edison, Kafe, Webinar 등이 있습니다.

한번의 인증절차만으로 연합인증 가입 서비스에 추가 로그인 없이 이용이 가능합니다.

다만, 연합인증을 위해서는 최초 1회만 인증 절차가 필요합니다. (회원이 아닐 경우 회원 가입이 필요합니다.)

연합인증 절차는 다음과 같습니다.

최초이용시에는
ScienceON에 로그인 → 연합인증 서비스 접속 → 로그인 (본인 확인 또는 회원가입) → 서비스 이용

그 이후에는
ScienceON 로그인 → 연합인증 서비스 접속 → 서비스 이용

연합인증을 활용하시면 KISTI가 제공하는 다양한 서비스를 편리하게 이용하실 수 있습니다.

Anti-inflammatory activity of Ternstroemia gymnanthera stem bark extracts in bacterial lipopolysaccharide-stimulated RAW264.7 murine macrophage cells 원문보기

Pharmaceutical biology, v.55 no.1, 2017년, pp.837 - 846  

Venkatesan, Thamizhiniyan (Department of Forest products and Biotechnology, College of Forest Science, Kookmin University , Seoul, South Korea) ,  Park, Eun-Jin (Department of Forest products and Biotechnology, College of Forest Science, Kookmin University , Seoul, South Korea) ,  Choi, Young-Woong (Department of Forest products and Biotechnology, College of Forest Science, Kookmin University , Seoul, South Korea) ,  Lee, Jennifer (Department of Forest products and Biotechnology, College of Forest Science, Kookmin University , Seoul, South Korea) ,  Kim, Young-Kyoon (Department of Forest products and Biotechnology, College of Forest Science, Kookmin University , Seoul, South Korea)

Abstract AI-Helper 아이콘AI-Helper

AbstractContext:Ternstroemia gymnanthera Sprague (Theaceae) possesses various known pharmacological properties. However, its anti-inflammatory activity has not been reported.Objective: The anti-inflammatory activity of Ternstroemia gymnanthera stem bark aqueous extract (TGSBE) was evaluated using LP...

주제어

참고문헌 (32)

  1. Abramson SB , Amin AR , Clancy RM , Attur M. 2001 The role of nitric oxide in tissue destruction . Best Pract Res Clin Rheumatol . 15 : 831 – 845 . 11812024 

  2. Aldridge C , Razzak A , Babcock TA , Helton WS , Espat NJ. 2008 Lipopolysaccharide-stimulated RAW 264.7 macrophage inducible nitric oxide synthase and nitric oxide production is decreased by an omega-3 fatty acid lipid emulsion . J Surg Res . 149 : 296 – 302 . 18262557 

  3. Bistrian B. 2007 Systemic response to inflammation . Nutr Rev . 65 : S170 – S172 . 18240543 

  4. Bogdan C , Röllinghoff M , Diefenbach A. 2000 The role of nitric oxide in innate immunity . Immunol Rev . 173 : 17 – 26 . 10719664 

  5. Bognar E , Sarszegi Z , Szabo A , Debreceni B , Kalman N , Tucsek Z , Sumegi B , Gallyas F. Jr. 2013 Antioxidant and anti-inflammatory effects in RAW264.7 macrophages of malvidin, a major red wine polyphenol . PLoS One . 8 : e65355 . 23755222 

  6. Carter AB , Knudtson KL , Monick MM , Hunninghake GW. 1999 The p38 mitogen-activated protein kinase is required for NF-kappaB-dependent gene expression. The role of TATA-binding protein (TBP) . J Biol Chem . 274 : 30858 – 30863 . 10521478 

  7. Chin MP , Schauer DB , Deen WM. 2008 Prediction of nitric oxide concentrations in colonic crypts during inflammation . Nitric Oxide . 19 : 266 – 275 . 18501201 

  8. Chiste RC , Freitas M , Mercadante AZ , Fernandes E. 2015 Superoxide anion radical: generation and detection in cellular and non-cellular systems . Curr Med Chem . 22 : 4234 – 4256 . 26511471 

  9. Ci X , Ren R , Xu K , Li H , Yu Q , Song Y , Wang D , Li R , Deng X. 2010 Schisantherin A exhibits anti-inflammatory properties by down-regulating NF-kappaB and MAPK signaling pathways in lipopolysaccharide-treated RAW 264.7 cells . Inflammation . 33 : 126 – 136 . 20238486 

  10. Costa G , Francisco V , Lopes MC , Cruz MT , Batista MT. 2012 Intracellular signaling pathways modulated by phenolic compounds: application for new anti-inflammatory drugs discovery . Curr Med Chem . 19 : 2876 – 2900 . 22519398 

  11. Dobrovolskaia MA , Vogel SN. 2002 Toll receptors, CD14, and macrophage activation and deactivation by LPS . Microbes Infect . 4 : 903 – 914 . 12106783 

  12. Evans JL , Goldfine ID , Maddux BA , Grodsky GM. 2003 Are oxidative stress-activated signaling pathways mediators of insulin resistance and beta-cell dysfunction? Diabetes . 52 : 1 – 8 . 12502486 

  13. Fang H , Pengal RA , Cao X , Ganesan LP , Wewers MD , Marsh CB , Tridandapani S. 2004 Lipopolysaccharide-induced macrophage inflammatory response is regulated by SHIP . J Immunol . 173 : 360 – 366 . 15210794 

  14. Fujihara M , Muroi M , Tanamoto K , Suzuki T , Azuma H , Ikeda H. 2003 Molecular mechanisms of macrophage activation and deactivation by lipopolysaccharide: roles of the receptor complex . Pharmacol Ther . 100 : 171 – 194 . 14609719 

  15. Góth L. 2006 [The hydrogen peroxide paradox] . Orv Hetil . 147 : 887 – 893 . 16784144 

  16. Guo W , Sun J , Jiang L , Duan L , Huo M , Chen N , Zhong W , Wassy L , Yang Z , Feng H. 2012 Imperatorin attenuates LPS-induced inflammation by suppressing NF-κB and MAPKs activation in RAW 264.7 macrophages . Inflammation . 35 : 1764 – 1772 . 22890309 

  17. Haddad JJ , Land SC. 2002 Redox/ROS regulation of lipopolysaccharide-induced mitogen-activated protein kinase (MAPK) activation and MAPK-mediated TNF-alpha biosynthesis . Br J Pharmacol . 135 : 520 – 536 . 11815388 

  18. Hong Byun E , Fujimura Y , Yamada K , Tachibana H. 2010 TLR4 signaling inhibitory pathway induced by green tea polyphenol epigallocatechin-3-gallate through 67-kDa laminin receptor . J Immunol . 185 : 33 – 45 . 20511545 

  19. Hsu HY , Wen MH. 2002 Lipopolysaccharide-mediated reactive oxygen species and signal transduction in the regulation of interleukin-1 gene expression . J Biol Chem . 277 : 22131 – 22139 . 11940570 

  20. Ikuta A , Tomiyasu H , Morita Y , Yoshimura K. 2003 Ursane- and oleanane-type triterpenes from Ternstroemia gymnanthera callus tissues . J Nat Prod . 66 : 1051 – 1054 . 12932122 

  21. Jou IM , Lin CF , Tsai KJ , Wei SJ. 2013 Macrophage-mediated inflammatory disorders . Mediators Inflamm . 2013 : 316482 . 23843681 

  22. Kazłowska K , Hsu T , Hou CC , Yang WC , Tsai GJ. 2010 Anti-inflammatory properties of phenolic compounds and crude extract from Porphyra dentata . J Ethnopharmacol . 128 : 123 – 130 . 20051261 

  23. Kim SY , Lee JG , Cho WS , Cho KH , Sakong J , Kim JR , Chin BR , Baek SH. 2010 Role of NADPH oxidase-2 in lipopolysaccharide-induced matrix metalloproteinase expression and cell migration . Immunol Cell Biol . 88 : 197 – 204 . 19935767 

  24. Laskin DL , Pendino KJ. 1995 Macrophages and inflammatory mediators in tissue injury . Annu Rev Pharmacol Toxicol . 35 : 655 – 677 . 7598511 

  25. Mogensen TH. 2009 Pathogen recognition and inflammatory signaling in innate immune defenses . Clin Microbiol Rev . 22 : 240 – 273 . 19366914 

  26. Panaro MA , Brandonisio O , Acquafredda A , Sisto M , Mitolo V. 2003 Evidences for iNOS expression and nitric oxide production in the human macrophages . Curr Drug Targets Immune Endocr Metab Disord . 3 : 210 – 221 . 

  27. Re R , Pellegrini N , Proteggente A , Pannala A , Yang M , Rice-Evans C. 1999 Antioxidant activity applying an improved ABTS radical cation decolorization assay . Free Radic Biol Med . 26 : 1231 – 1237 . 10381194 

  28. Sone Y , Moon JK , Mai TT , Thu NN , Asano E , Yamaguchi K , Otsuka Y , Shibamoto T. 2011 Antioxidant/anti-inflammatory activities and total phenolic content of extracts obtained from plants grown in Vietnam . J Sci Food Agric . 91 : 2259 – 2264 . 21547923 

  29. Wang P , Qiao Q , Li J , Wang W , Yao LP , Fu YJ. 2016 Inhibitory effects of geraniin on LPS-induced inflammation via regulating NF-κB and Nrf2 pathways in RAW 264.7 cells . Chem Biol Interact . 253 : 134 – 142 . 27181634 

  30. Wu C , Zhao W , Zhang X , Chen X. 2015 Neocryptotanshinone inhibits lipopolysaccharide-induced inflammation in RAW264.7 macrophages by suppression of NF-κB and iNOS signaling pathways . Acta Pharm Sin B . 5 : 323 – 329 . 26579462 

  31. Yun KJ , Kim JY , Kim JB , Lee KW , Jeong SY , Park HJ , Jung HJ , Cho YW , Yun K , Lee KT. 2008 Inhibition of LPS-induced NO and PGE2 production by asiatic acid via NF-kappa B inactivation in RAW 264.7 macrophages: possible involvement of the IKK and MAPK pathways . Int Immunopharmacol . 8 : 431 – 441 . 18279797 

  32. Zuo L , Zhou T , Pannell BK , Ziegler AC , Best TM. 2015 Biological and physiological role of reactive oxygen species-the good, the bad and the ugly . Acta Physiol (Oxf) . 214 : 329 – 348 . 25912260 

관련 콘텐츠

오픈액세스(OA) 유형

GOLD

오픈액세스 학술지에 출판된 논문

이 논문과 함께 이용한 콘텐츠

저작권 관리 안내
섹션별 컨텐츠 바로가기

AI-Helper ※ AI-Helper는 오픈소스 모델을 사용합니다.

AI-Helper 아이콘
AI-Helper
안녕하세요, AI-Helper입니다. 좌측 "선택된 텍스트"에서 텍스트를 선택하여 요약, 번역, 용어설명을 실행하세요.
※ AI-Helper는 부적절한 답변을 할 수 있습니다.

선택된 텍스트

맨위로