$\require{mediawiki-texvc}$

연합인증

연합인증 가입 기관의 연구자들은 소속기관의 인증정보(ID와 암호)를 이용해 다른 대학, 연구기관, 서비스 공급자의 다양한 온라인 자원과 연구 데이터를 이용할 수 있습니다.

이는 여행자가 자국에서 발행 받은 여권으로 세계 각국을 자유롭게 여행할 수 있는 것과 같습니다.

연합인증으로 이용이 가능한 서비스는 NTIS, DataON, Edison, Kafe, Webinar 등이 있습니다.

한번의 인증절차만으로 연합인증 가입 서비스에 추가 로그인 없이 이용이 가능합니다.

다만, 연합인증을 위해서는 최초 1회만 인증 절차가 필요합니다. (회원이 아닐 경우 회원 가입이 필요합니다.)

연합인증 절차는 다음과 같습니다.

최초이용시에는
ScienceON에 로그인 → 연합인증 서비스 접속 → 로그인 (본인 확인 또는 회원가입) → 서비스 이용

그 이후에는
ScienceON 로그인 → 연합인증 서비스 접속 → 서비스 이용

연합인증을 활용하시면 KISTI가 제공하는 다양한 서비스를 편리하게 이용하실 수 있습니다.

Inefficient skeletal muscle oxidative function flanks impaired motor neuron recruitment in Amyotrophic Lateral Sclerosis during exercise 원문보기

Scientific reports, v.7, 2017년, pp.2951 -   

Lanfranconi, F. (School of Medicine and Surgery and Milan Center for Neuroscience (NeuroMI), University of Milano-Bicocca, Milano, Italy) ,  Ferri, A. (School of Medicine and Surgery and Milan Center for Neuroscience (NeuroMI), University of Milano-Bicocca, Milano, Italy) ,  Corna, G. (School of Medicine and Surgery and Milan Center for Neuroscience (NeuroMI), University of Milano-Bicocca, Milano, Italy) ,  Bonazzi, R. (School of Medicine and Surgery and Milan Center for Neuroscience (NeuroMI), University of Milano-Bicocca, Milano, Italy) ,  Lunetta, C. (NEuroMuscular Omnicentre (NEMO), Fondazione Serena Onlus, Milano, Italy) ,  Silani, V. (Department of Neurology and Laboratory Neuroscience –) ,  Riva, N. (IRCCS Istituto Auxologico Italiano, Pioltello, Italy) ,  Rigamonti, A. (San Raffaele Hospital, Milano, Italy) ,  Maggiani, A. (Alessandro Manzoni Hospital, Lecco, Italy) ,  Ferrarese, C. (Italian Academy of Osteopathic Medicine (AIMO), Saronno, Italy) ,  Tremolizzo, L. (School of Medicine and Surgery and Milan Center for Neuroscience (NeuroMI), University of Milano-Bicocca, Milano, Italy)

Abstract AI-Helper 아이콘AI-Helper

This study aimed to evaluate muscle oxidative function during exercise in amyotrophic lateral sclerosis patients (pALS) with non-invasive methods in order to assess if determinants of reduced exercise tolerance might match ALS clinical heterogeneity. 17 pALS, who were followed for 4 months, were com...

참고문헌 (25)

  1. 1. Mezzani A Reduced exercise capacity in early-stage amyotrophic lateral sclerosis: Role of skeletal muscle Amyotroph Lateral Scler 2012 13 87 94 10.3109/17482968.2011.601463 21830991 

  2. 2. Simon NG Quantifying disease progression in amyotrophic lateral sclerosis Ann Neurol. 2014 76 643 657 10.1002/ana.24273 25223628 

  3. 3. Sharma KR Physiology of fatigue in amyotrofic lateral sclerosis Neurology. 1995 45 733 740 10.1212/WNL.45.4.733 7723963 

  4. 4. Dal Bello-Haas V Florence JM Therapeutic exercise for people with amyotrophic lateral sclerosis or motor neuron disease Cochrane Database Syst Rev 2013 5 CD005229 

  5. 5. Echantez-Laguna A Mitochondrial respiratory chain function in skeletal muscle of ALS patients Ann Neurol. 2002 52 623 627 10.1002/ana.10357 12402260 

  6. 6. Aboussouan LS Mechanism of exercise limitation and pulmonary rehabilitation for patients with neuromuscular disease Chronic Resp Dis 2009 6 231 249 10.1177/1479972309345927 

  7. 7. Finsterer J Lactate stress testing in sporadic amyotrophic lateral sclerosis Int J Neurosci 2005 115 583 591 10.1080/00207450590522847 15809220 

  8. 8. Siciliano G Impaired oxidative metabolism in exercising muscle from ALS patients J Neurol Sci 2009 191 61 65 10.1016/S0022-510X(01)00620-7 

  9. 9. Lanfranconi F Near infrared spectroscopy (NIRS) as a new non-invasive tool to detect oxidative skeletal muscle impairment in children survived to acute lymphoblastic leukaemia PLoS One. 2014 9 e99282 10.1371/journal.pone.0099282 24956391 

  10. 10. Lanfranconi F Noninvasive evaluation of skeletal muscle oxidative metabolism after heart transplant Med Sci Sports Exerc 2006 38 1374 1383 10.1249/01.mss.0000228943.62776.69 16888448 

  11. 11. Ferrari M Mottola L Quaresima V Principles, technique and limitations of near infrared spectroscopy Can J Appl Physiol 2004 29 463 487 10.1139/h04-031 15328595 

  12. 12. Grassi B Quaresima V Near-infrared spectroscopy and skeletal muscle oxidative function in vivo in health and disease: a review from an exercise physiology perspective J Biomed Opt 2016 21 091313 10.1117/1.JBO.21.9.091313 27443955 

  13. 13. Ryan TE Skeletal muscle oxidative capacity in amyotrophic lateral sclerosis Muscle Nerve. 2014 50 767 774 10.1002/mus.24223 24616062 

  14. 14. Nichols NL Ventilatory control in ALS Respir Physiol Neurobiol 2013 189 429 437 10.1016/j.resp.2013.05.016 23692930 

  15. 15. Cedarbaum JM The ALSFRS-R: a revised ALS functional rating scale that incorporates assessments of respiratory function. BDNF ALS Study Group (Phase III) J Neurol Sci 1999 169 13 12 10.1016/S0022-510X(99)00210-5 10540002 

  16. 16. Kollewe K ALSFRS-R score and its ratio: a useful predictor for ALS-progression J Neurol Sci 2008 275 69 73 10.1016/j.jns.2008.07.016 18721928 

  17. 17. Vellas B The Mini Nutritional Assessment (MNA) and its use in grading the nutritional state of elderly patients Nutrition. 1999 15 116 122 10.1016/S0899-9007(98)00171-3 9990575 

  18. 18. Jackson AS Pollock ML Generalized equations for predicting body density of men Br J Nutr 1978 40 497 504 10.1079/BJN19780152 718832 

  19. 19. Jackson AS Pollock ML Ward A Generalized equations for predicting body density of women Med Sci Sports Exerc 1980 12 175 181 7402053 

  20. 20. Borg GA Psychophysical bases of perceived exertion Med Sci Sports Exerc 1982 14 377 381 7154893 

  21. 21. Grassi B Impaired oxygen extraction in metabolic myopathies: detection and quantification by near-infrared spectroscopy Muscle Nerve. 2007 35 510 520 10.1002/mus.20708 17143893 

  22. 22. Al Sarraj S Mitochondrial abnormalities and low grade inflammation are present in the skeletal muscle of a minority of patients with amyotrophic lateral sclerosis; an observational myopathology study Acta Neuropathol Commun 2014 2 165 10.1186/s40478-014-0165-z 25510661 

  23. 23. Taivassalo T The spectrum of exercise tolerance in mitochondrial myopathies: a study of 40 patients Brain. 2003 126 413 423 10.1093/brain/awg028 12538407 

  24. 24. Brockington A Unravelling the enigma of selective vulnerability in neurodegeneration: motor neurons resistant to degeneration in ALS show distinct gene expression characteristics and decreased susceptibility to excitotoxicity Acta Neuropathol. 2013 125 95 109 10.1007/s00401-012-1058-5 23143228 

  25. 25. Ngo ST Stein FJ McCombe PA Body mass index and dietary intervention: implications for prognosis of amyotrophic lateral sclerosis J Neurol Sci 2014 340 5 12 10.1016/j.jns.2014.02.035 24629478 

관련 콘텐츠

오픈액세스(OA) 유형

GOLD

오픈액세스 학술지에 출판된 논문

저작권 관리 안내
섹션별 컨텐츠 바로가기

AI-Helper ※ AI-Helper는 오픈소스 모델을 사용합니다.

AI-Helper 아이콘
AI-Helper
안녕하세요, AI-Helper입니다. 좌측 "선택된 텍스트"에서 텍스트를 선택하여 요약, 번역, 용어설명을 실행하세요.
※ AI-Helper는 부적절한 답변을 할 수 있습니다.

선택된 텍스트

맨위로