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Telomere Length and Bipolar Disorder 원문보기

Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, v.43 no.2, 2018년, pp.445 - 453  

Powell, Timothy R (Social, Genetic and Developmental Psychiatry, Institute of Psychiatry, Psychology and Neuroscience, King’s College London , London, UK) ,  Dima, Danai (Department of Psychology, City, University of London , London, UK) ,  Frangou, Sophia (Department of Psychiatry, Icahn School of Medicine at Mount Sinai , New York, NY, USA) ,  Breen, Gerome (Social, Genetic and Developmental Psychiatry, Institute of Psychiatry, Psychology and Neuroscience, King’s College London , London, UK)

Abstract AI-Helper 아이콘AI-Helper

Variation in telomere length is heritable and is currently considered a promising biomarker of susceptibility for neuropsychiatric disorders, particularly because of its association with memory function and hippocampal morphology. Here, we investigate telomere length in connection to familial risk a...

참고문헌 (108)

  1. Allsopp RC, Vaziri H, Patterson C, Goldstein S, Younglai EV, Futcher AB et al ( 1992 ). Telomere length predicts replicative capacity of human fibroblasts . Proc Natl Acad Sci USA 89 : 10114 –10118. 1438199 

  2. American Psychiatric Association ( 1994 ) Diagnostic and Statistical Manual of Mental Disorders , 4th edn. American Psychiatric Press: Washington, DC. 

  3. Barbé-Tuana FM, Parisi MM, Panizzutti BS, Fries GR, Grun LK, Guma FT et al ( 2016 ). Shortened telomere length in bipolar disorder: a comparison of the early and late stages of disease . Rev Bras Psiquiatr 38 : 281 –286. 27798713 

  4. Barnes J, Bartlett JW, van de Pol LA, Loy CT, Scahill RI, Frost C et al ( 2009 ). A meta-analysis of hippocampal atrophy rates in Alzheimer's disease . Neurobiol Aging 30 : 1711 –1723. 18346820 

  5. Bersani FS, Lindqvist D, Mellon SH, Penninx BW, Verhoeven JE, Révész D et al ( 2015 ). Telomerase activation as a possible mechanism of action for psychopharmacological interventions . Drug Discov Today 20 : 1305 –1309. 26166813 

  6. Beyer J, Kuchibhatla M, Gersing K, Krishnan KR ( 2005 ). Medical comorbidity in a bipolar outpatient clinical population . Neuropsychopharmacology 30 : 401 –404. 15536492 

  7. Blackburn EH ( 1991 ). Structure and function of telomeres . Nature 350 : 569 –573. 1708110 

  8. Bora E, Harrison BJ, Yücel M, Pantelis C ( 2013 ). Cognitive impairment in euthymic major depressive disorder: a meta-analysis . Psychol Med 43 : 2017 –2026. 23098294 

  9. Bora E, Yucel M, Pantelis C ( 2009 ). Cognitive endophenotypes of bipolar disorder: a meta-analysis of neuropsychological deficits in euthymic patients and their first-degree relatives . J Affect Disord 113 : 1 –20. 18684514 

  10. Bourne C, Aydemir Ö, Balanzá-Martínez V, Bora E, Brissos S, Cavanagh JT et al ( 2013 ). Neuropsychological testing of cognitive impairment in euthymic bipolar disorder: an individual patient data meta-analysis . Acta Psychiatr Scand 128 : 149 –162. 23617548 

  11. Brouilette S, Singh RK, Thompson JR, Goodall AH, Samani NJ ( 2003 ). White cell telomere length and risk of premature myocardial infarction . Arterioscler Thromb Vasc Biol 23 : 842 –846. 12649083 

  12. Calado RT, Young NS ( 2009 ). Telomere diseases . N Engl J Med 361 : 2353 –2365. 20007561 

  13. Cawthon RM ( 2009 ). Telomere length measurement by a novel monochrome multiplex quantitative PCR method . Nucleic Acids Res 37 : e21 . 19129229 

  14. Cherkas LF, Hunkin JL, Kato BS, Richards JB, Gardner JP, Surdulescu GL et al ( 2008 ). The association between physical activity in leisure time and leukocyte telomere length . Arch Intern Med 168 : 154 –158. 18227361 

  15. Colpo GD, Leffa DD, Köhler CA, Kapczinski F, Quevedo J, Carvalho AF ( 2015 ). Is bipolar disorder associated with accelerating aging? A meta-analysis of telomere length studies . J Affect Disord 186 : 241 –248. 26253905 

  16. Czepielewski L, Filho LD, Brietzke E, Grassi-Oliveira R ( 2013 ). Bipolar disorder and metabolic syndrome: a systematic review . Rev Bras Psiquiatr 35 : 88 –93. 23567607 

  17. Damjanovic AK, Yang Y, Glaser R, Kiecolt-Glaser JK, Nguyen H, Laskowski B et al ( 2007 ). Accelerated telomere erosion is associated with a declining immune function of caregivers of Alzheimer's disease patients . J Immunol 179 : 4249 –4254. 17785865 

  18. Darrow SM, Verhoeven JE, Révész D, Lindqvist D, Penninx BW, Delucchi KL et al ( 2016 ). The association between psychiatric disorders and telomere length: a meta-analysis involving 14,827 persons . Psychosom Med 78 : 776 –787. 27359174 

  19. da Silva J, Gonçalves-Pereira M, Xavier M, Mukaetova-Ladinska EB ( 2013 ). Affective disorders and risk of developing dementia: systematic review . Br J Psychiatry 202 : 177 –186. 23457181 

  20. Delvecchio G, Dima D, Frangou S ( 2015 ). The effect of ANK3 bipolar-risk polymorphisms on the working memory circuitry differs between loci and according to risk-status for bipolar disorder . Am J Med Genet B Neuropsychiatr Genet 168B : 188 –196. 25711502 

  21. Demissie S, Levy D, Benjamin EJ, Cupples LA, Gardner JP, Herbert A et al ( 2006 ). Insulin resistance, oxidative stress, hypertension, and leukocyte telomere length in men from the Framingham Heart Study . Aging Cell 5 : 325 –330. 16913878 

  22. Dickerson BC, Eichenbaum H ( 2010 ). The episodic memory system: neurocircuitry and disorders . Neuropsychopharmacology 35 : 86 –104. 19776728 

  23. Dima D, Roberts RE, Frangou S ( 2016 ). Connectomic markers of disease expression, genetic risk and resilience in bipolar disorder . Transl Psychiatry 6 : e706 . 26731443 

  24. Dima D, Jogia J, Collier D, Vassos E, Burdick KE, Frangou S ( 2013 ). Independent modulation of engagement and connectivity of the facial network during affect processing by CACNA1C and ANK3 risk genes for bipolar disorder . JAMA Psychiatry 70 : 1303 –1311. 24108394 

  25. Dlouha D, Maluskova J, Kralova Lesna I, Lanska V, Hubacek JA ( 2014 ). Comparison of the relative telomere length measured in leukocytes and eleven different human tissues . Physiol Res 63 (Suppl 3): S343 –S350. 25428739 

  26. D’Mello MJJ, Ross SA, Briel M, Anand SS, Gerstein H, Paré G ( 2015 ). Association between shortened leukocyte telomere length and cardiometabolic outcomes: systematic review and meta-analysis . Circ. Cardiovasc Genet 8 : 82 –90. 25406241 

  27. Eitan E, Hutchison ER, Mattson MP ( 2014 ). Telomere shortening in neurological disorders: an abundance of unanswered questions . Trends Neurosci 37 : 256 –263. 24698125 

  28. Epel ES, Blackburn EH, Lin J, Dhabhar FS, Adler NE, Morrow JD et al ( 2004 ). Accelerated telomere shortening in response to life stress . Proc Natl Acad Sci USA 101 : 17312 –17315. 15574496 

  29. Epel ES, Merkin SS, Cawthon R, Blackburn EH, Adler NE, Pletcher MJ et al ( 2008 ). The rate of leukocyte telomere shortening predicts mortality from cardiovascular disease in elderly men . Aging (Albany NY) 1 : 81 –88. 20195384 

  30. Farzaneh-Far R, Lin J, Epel E, Lapham K, Blackburn E, Whooley MA ( 2010 ). Telomere length trajectory and its determinants in persons with coronary artery disease: longitudinal findings from the heart and soul study . PLoS ONE 5 : e8612 . 20072607 

  31. Fiedorowicz JG, Palagummi NM, Behrendtsen O, Coryell WH ( 2010 ). Cholesterol and affective morbidity . Psychiatry Res 175 : 78 –81. 19969372 

  32. First MB, Spitzer RL, Gibbon M, Williams JBW ( 2002 a) Structured Clinical Interview for DSM-IV-TR Axis I Disorders, Research Version, Non-Patient Edition . Biometrics Research, New York State Psychiatric Institute: New York, NY. 

  33. First MB, Spitzer RL, Gibbon M, Williams JBW ( 2002 b) Structured Clinical Interview for DSM-IV-TR Axis I Disorders, Research Version, Patient Edition . Biometrics Research, New York State Psychiatric Institute: New York, NY. 

  34. Fitzpatrick AL, Kronmal RA, Gardner JP, Psaty BM, Jenny NS, Tracy RP et al ( 2007 ). Leukocyte telomere length and cardiovascular disease in the cardiovascular health study . Am J Epidemiol 165 : 14 –21. 17043079 

  35. Forcada I, Papachristou E, Mur M, Christodoulou T, Jogia J, Reichenberg A et al ( 2011 ). The impact of general intellectual ability and white matter volume on the functional outcome of patients with bipolar disorder and their relatives . J Affect Disord 130 : 413 –420. 21112093 

  36. Forty L, Ulanova A, Jones L, Jones I, Gordon-Smith K, Fraser C et al ( 2014 ). Comorbid medical illness in bipolar disorder . Br J Psychiatry 205 : 465 –472. 25359927 

  37. Frangou S ( 2009 ). Risk and resilience in bipolar disorder: rationale and design of the Vulnerability to Bipolar Disorders Study (VIBES) . Biochem Soc Trans 37 : 1085 –1089. 19754457 

  38. Frangou S ( 2011 ). Brain structural and functional correlates of resilience to bipolar disorder . Front Hum Neurosci 5 : 184 . 22363273 

  39. Freeman B, Smith N, Curtis C, Huckett L, Mill J, Craig IW ( 2003 ). DNA from buccal swabs recruited by mail: evaluation of storage effects on long-term stability and suitability for multiplex polymerase chain reaction genotyping . Behav Genet 33 : 67 –72. 12645823 

  40. Friedrich U, Griese E, Schwab M, Fritz P, Thon K, Klotz U ( 2000 ). Telomere length in different tissues of elderly patients . Mech Ageing Dev 119 : 89 –99. 11080530 

  41. Gage FH, Coates PW, Palmer TD, Kuhn HG, Fisher LJ, Suhonen JO et al ( 1995 ). Survival and differentiation of adult neuronal progenitor cells transplanted to the adult brain . Proc Natl Acad Sci USA 25 : 11879 –11883. 

  42. Gianaros PJ, Jennings JR, Sheu LK, Greer PJ, Kuller LH, Matthews KA ( 2007 ). Prospective reports of chronic life stress predict decreased grey matter volume in the hippocampus . Neuroimage 35 : 795 –803. 17275340 

  43. Hamilton M ( 1960 ). A rating scale for depression . J Neurol Neurosurg Psychiatry 23 : 56 –62. 14399272 

  44. Hartmann N, Boehner M, Groenen F, Kalb R ( 2010 ). Telomere length of patients with major depression is shortened but independent from therapy and severity of the disease . Depress Anxiety 27 : 1111 –1116. 21053332 

  45. Heidinger BJ, Blount JD, Boner W, Griffiths K, Metcalfe NB, Monaghan P ( 2011 ). Telomere length in early life predicts lifespan . Proc Natl Acad Sci USA 109 : 1743 –1748. 

  46. Hibar DP, Westlye LT, van Erp TG, Rasmussen J, Leonardo CD, Faskowitz J et al ( 2016 ). Subcortical volumetric abnormalities in bipolar disorder . Mol Psychiatry 21 : 1710 –1716. 26857596 

  47. Hoen PW, de Jonge P, Na BY, Farzaneh-Far R, Epel E, Lin J et al ( 2011 ). Depression and leukocyte telomere length in patients with coronary heart disease: data from the Heart and Soul Study . Psychosom Med 73 : 541 –547. 21597035 

  48. Jaskelioff M, Muller FL, Paik JH, Thomas E, Jiang S, Adams AC et al ( 2011 ). Telomerase reactivation reverses tissue degeneration in aged telomerase-deficient mice . Nature 469 : 102 –106. 21113150 

  49. Jogia J, Dima D, Kumari V, Frangou S ( 2012 ). Frontopolar cortical inefficiency may underpin reward and working memory dysfunction in bipolar disorder . World J Biol Psychiatry 13 : 605 –615. 21812622 

  50. Jogia J, Ruberto G, Lelli-Chiesa G, Vassos E, Maierú M, Tatarelli R et al ( 2011 ). The impact of the CACNA1C gene polymorphism on frontolimbic function in bipolar disorder . Mol Psychiatry 16 : 1070 –1071. 21519340 

  51. Kempton MJ, Haldane M, Jogia J, Grasby PM, Collier D, Frangou S ( 2009 ). Dissociable brain structural changes associated with predisposition, resilience, and disease expression in bipolar disorder . J Neurosci 29 : 10863 –10868. 19726644 

  52. Kessing LV, Nilsson FM ( 2003 ). Increased risk of developing dementia in patients with major affective disorders compared to patients with other medical illnesses . J Affect Disord 73 : 261 –269. 12547295 

  53. Kessing LV, Sondergard L, Forman JL, Andersen PK ( 2008 ). Lithium treatment and risk of dementia . Arch Gen Psychiatry 65 : 1331 –1335. 18981345 

  54. King KS, Kozlitina J, Rosenberg RN, Peshock RM, McColl RW, Garcia CK ( 2014 ). Effect of leukocyte telomere length on total and regional brain volumes in a large population-based cohort . JAMA Neurol 71 : 1247 –1254. 25090243 

  55. Kühn S, Gallinat J ( 2014 ). Segregating cognitive functions within hippocampal formation: a quantitative meta-analysis on spatial navigation and episodic memory . Hum Brain Mapp 35 : 1129 –1142. 23362184 

  56. Lelli-Chiesa G, Kempton MJ, Jogia J, Tatarelli R, Girardi P, Powell J et al ( 2011 ). The impact of the Val158Met catechol-O-methyltransferase genotype on neural correlates of sad facial affect processing in patients with bipolar disorder and their relatives . Psychol Med 41 : 779 –788. 20667170 

  57. Lim J, Oh IK, Han C, Huh YJ, Jung IK, Patkar AA et al ( 2013 ). Sensitivity of cognitive tests in four cognitive domains in discriminating MDD patients from healthy controls: a meta-analysis . Int Psychogeriatr 25 : 1543 –1557. 23725644 

  58. Lima IM, Barros A, Rosa DV, Albuquerque M, Malloy-Diniz L, Neves FS et al ( 2015 ). Analysis of telomere attrition in bipolar disorder . J Affect Disord 172 : 43 –47. 25451394 

  59. Lu W, Zhang Y, Liu D, Songyang Z, Wan M ( 2013 ). Telomeres-structure, function, and regulation . Exp Cell Res 319 : 133 –141. 23006819 

  60. Lung FW, Chen NC, Shu BC ( 2007 ). Genetic pathway of major depressive disorder in shortening telomeric length . Psychiatr Genet 17 : 195 –199. 17417064 

  61. Maina G, Salvi V, Vitalucci A, D'Ambrosio V, Bogetto F ( 2008 ). Prevalence and correlates of overweight in drug-naïve patients with bipolar disorder . J Affect Disord 110 : 149 –155. 18234351 

  62. Mamdani F, Rollins B, Morgan L, Myers RM, Barchas JD, Schatzberg AF et al ( 2015 ). Variable telomere length across post-mortem human brain regions and specific reduction in the hippocampus of major depressive disorder . Transl Psychiatry 5 : e636 . 26371764 

  63. Martinsson L, Wei Y, Xu D, Melas PA, Mathé AA, Schalling M et al ( 2013 ). Long-term lithium treatment in bipolar disorder is associated with longer leukocyte telomeres . Transl Psychiatry 3 : e261 . 23695236 

  64. Masi S, Nightingale CM, Day IN, Guthrie P, Rumley A, Lowe GD et al ( 2012 ). Inflammation and not cardiovascular risk factors is associated with short leukocyte telomere length in 13- to 16-year-old adolescents . Arterioscler Thromb Vasc Biol 32 : 2029 –2034. 22679311 

  65. McIntyre RS, Konarski JZ, Soczynska JK, Wilkins K, Panjwani G, Bouffard B et al ( 2006 ). Medical comorbidity in bipolar disorder: implications for functional outcomes and health service utilization . Psychiatr Serv 57 : 1140 –1144. 16870965 

  66. McIntyre RS, Danilewitz M, Liauw SS, Kemp DE, Nguyen HT, Kahn LS et al ( 2010 ). Bipolar disorder and metabolic syndrome: an international perspective . J Affect Disord 126 : 366 –387. 20541810 

  67. Mothi SS, Tandon N, Padmanabhan J, Mathew IT, Clementz B, Tamminga C et al ( 2015 ). Increased cardiometabolic dysfunction in first-degree relatives of patients with psychotic disorders . Schizophr Res 165 : 103 –107. 25900543 

  68. Mouiha A, Duchesne S Alzheimer’s Disease Neuroimaging Initiative ( 2011 ). Hippocampal atrophy rates in Alzheimer’s disease: automated segmentation variability analysis . Neurosci Lett 495 : 6 –10. 21371528 

  69. Nilsonne G, Tamm S, Månsson KN, Åkerstedt T, Lekander M ( 2015 ). Leukocyte telomere length and hippocampus volume: a meta-analysis . F1000Res 4 : 1073 . 26674112 

  70. O’Donnell CJ, Demissie S, Kimura M, Levy D, Gardner JP, White C et al ( 2008 ). Leukocyte telomere length and carotid artery intimal medial thickness: the Framingham Heart Study . Arterioscler Thromb Vasc Biol 28 : 1165 –1171. 18388332 

  71. O'Donovan A, Pantell MS, Puterman E, Dhabhar FS, Blackburn EH, Yaffe K et al ( 2011 ). Cumulative inflammatory load is associated with short leukocyte telomere length in the Health, Aging and Body Composition Study . PLoS ONE 6 : e19687 . 21602933 

  72. Palmer TD, Takahashi J, Gage FH ( 1997 ). The adult rat hippocampus contains primordial neural stem cells . Mol Cell Neurosci 8 : 389 –404. 9143557 

  73. Panossian LA, Porter VR, Valenzuela HF, Zhu X, Reback E, Masterman D et al ( 2003 ). Telomere shortening in T cells correlates with Alzheimer’s disease status . Neurobiol Aging 24 : 77 –84. 12493553 

  74. Perrier E, Pompei F, Ruberto G, Vassos E, Collier D, Frangou S ( 2011 ). Initial evidence for the role of CACNA1C on subcortical brain morphology in patients with bipolar disorder . Eur Psychiatry 26 : 135 –137. 21292451 

  75. Pompei F, Dima D, Rubia K, Kumari V, Frangou S ( 2011 a). Dissociable functional connectivity changes during the Stroop task relating to risk, resilience and disease expression in bipolar disorder . Neuroimage 57 : 576 –582. 21570470 

  76. Pompei F, Jogia J, Tatarelli R, Girardi P, Rubia K, Kumari V et al ( 2011 b). Familial and disease specific abnormalities in the neural correlates of the Stroop Task in bipolar disorder . Neuroimage 56 : 1677 –1684. 21352930 

  77. Rabinovici GD, Seeley WW, Kim EJ, Gorno-Tempini ML, Rascovsky K, Pagliaro TA et al ( 2007 ). Distinct MRI atrophy patterns in autopsy-proven Alzheimer’s disease and frontotemporal lobar degeneration . Am J Alzheimers Dis Other Demen 22 : 474 –488. 18166607 

  78. Regenold WT, Thapar RK, Marano C, Gavirneni S, Kondapavuluru PV ( 2002 ). Increased prevalence of type 2 diabetes mellitus among psychiatric inpatients with bipolar I affective and schizoaffective disorders independent of psychotropic drug use . J Affect Disord 70 : 19 –26. 12113916 

  79. Ruberto G, Vassos E, Lewis CM, Tatarelli R, Girardi P, Collier D et al ( 2011 ). The cognitive impact of the ANK3 risk variant for bipolar disorder: initial evidence of selectivity to signal detection during sustained attention . PLoS ONE 6 : e16671 . 21304963 

  80. Saretzki G, Von Zglinicki T ( 2002 ). Replicative aging, telomeres, and oxidative stress . Ann NY Acad Sci 959 : 24 –29. 11976182 

  81. Schmaal L, Veltman DJ, van Erp TG, Sämann PG, Frodl T, Jahanshad N et al ( 2016 ). Subcortical brain alterations in major depressive disorder: findings from the ENIGMA Major Depressive Disorder working group . Mol Psychiatry 21 : 806 –812. 26122586 

  82. Shalev I, Moffit TE, Sugden K, Williams B, Houts RM, Danese A et al ( 2013 ). Exposure to violence during childhood is associated with telomere erosion from 5 to 10 years of age: a longitudinal study . Mol. Psychiatry 18 : 576 –581. 22525489 

  83. Shingu T, Jaskelioff M, Yuan L, Ding Z, Protopopov A, Kost-Alimova M et al ( 2015 ). Utilizing murine inducible telomerase alleles in the studies of tissue degeneration/regeneration and cancer . J Vis Exp 98 : 1 –8. 

  84. Simon NM, Smoller JW, McNamara KL, Maser RS, Zalta AK, Pollack MH et al ( 2006 ). Telomere shortening and mood disorders: Preliminary support for a chronic stress model of accelerated aging . Biol Psychiatry 60 : 432 –435. 16581033 

  85. Slagboom PE, Droog S, Boomsma DI ( 1994 ). Genetic determination of telomere size in humans: a twin study of three age groups . Am J Hum Genet 55 : 876 –882. 7977349 

  86. Smith DJ, Martin D, McLean G, Langan J, Guthrie B, Mercer SW ( 2013 ). Multimorbidity in bipolar disorder and undertreatment of cardiovascular disease: a cross sectional study . BMC Med 11 : 263 . 24359325 

  87. Spalding KL, Bergmann O, Alkass K, Bernard S, Salehpour M, Huttner HB et al ( 2013 ). Dynamics of hippocampal neurogenesis in adult humans . Cell 153 : 1219 –1227. 23746839 

  88. Soeiro-de-Souza MG, Teixeira AL, Mateo EC, Zanetti MV, Rodrigues FG, de Paula VJ et al ( 2014 ). Leukocyte telomerase activity and antidepressant efficacy in bipolar disorder . Eur Neuropsychopharmacol 24 : 1139 –1143. 24731723 

  89. Squassina A, Pisanu C, Congiu D, Caria P, Frau D, Niola P et al ( 2016 ). Leukocyte telomere length positively correlates with duration of lithium treatment in bipolar disorder patients . Eur Neuropsychopharmacol 26 : 1241 –1247. 27084304 

  90. Stewart JA, Chaiken MF, Wang F, Price CM ( 2012 ). Maintaining the end: roles of telomere proteins in end-protection, telomere replication and length regulation . Mutat Res 730 : 12 –19. 21945241 

  91. Szöke A, Trandafir A, Dupont ME, Méary A, Schürhoff F, Leboyer M ( 2008 ). Longitudinal studies of cognition in schizophrenia: meta-analysis . Br J Psychiatry 192 : 248 –257. 18378982 

  92. Takahashi T, Walterfang M, Wood SJ, Kempton MJ, Jogia J, Lorenzetti V et al ( 2010 ). Pituitary volume in patients with bipolar disorder and their first-degree relatives . J Affect Disord 124 : 256 –261. 20022640 

  93. Thomas P, O’Callaghan NJ, Fenech M ( 2008 ). Telomere length in white blood cells, buccal cells and brain tissue and its variation with ageing and Alzheimer’s disease . Mech Ageing Dev 129 : 183 –190. 18242664 

  94. Tohen M, Frank E, Bowden CL, Colom F, Ghaemi SN, Yatham LN et al ( 2009 ). The International Society for Bipolar Disorders (ISBD) Task Force report on the nomenclature of course and outcome in bipolar disorders . Bipolar Disord 11 : 453 –473. 19624385 

  95. Valdes AM, Andrew T, Gardner JP, Kimura M, Oelsner E, Cherkas LF et al ( 2005 ). Obesity, cigarette smoking, and telomere length in women . Lancet 366 : 662 –664. 16112303 

  96. Valdes AM, Deary IJ, Gardner J, Kimura M, Lu X, Spector TD et al ( 2010 ). Leukocyte telomere length is associated with cognitive performance in healthy women . Neurobiol Aging 31 : 986 –992. 18718693 

  97. van Erp TG, Hibar DP, Rasmussen JM, Glahn DC, Pearlson GD, Andreassen OA et al ( 2016 ). Subcortical brain volume abnormalities in 2028 individuals with schizophrenia and 2540 healthy controls via the ENIGMA consortium . Mol Psychiatry 21 : 585 . 26283641 

  98. Van Petten C ( 2004 ). Relationship between hippocampal volume and memory ability in healthy individuals across the lifespan: review and meta-analysis . Neuropsychologia 42 : 1394 –1413. 15193947 

  99. Verhoeven JE, van Oppen P, Révész D, Wolkowitz OM, Penninx BWJH ( 2016 ). Depressive and anxiety disorders showing robust, but non-dynamic, 6-year longitudinal association with short leukocyte telomere length . Am J Psychiatry 173 : 617 –624. 26940806 

  100. Verhoeven JE, Révész D, Picard M, Epel EE, Wolkowitz OM, Matthews KA et al ( 2017 ). Depression, telomeres and mitochondrial DNA: between- and within-person associations from a 10-year longitudinal study . Mol Psychiatry doi: 10.1038/mp.2017.48 (e-pub ahead of print). 

  101. Vincent J, Hovatta I, Frissa S, Goodwin L, Hotopf M, Hatch SL et al ( 2017 ). Assessing the contributions of childhood maltreatment subtypes and depression case-control status on telomere length reveals a specific role of physical neglect . J Affect Disord 213 : 16 –22. 28187293 

  102. Wei YB, Backlund L, Wegener G, Mathé AA, Lavebratt C ( 2015 ). Telomerase dysregulation in the hippocampus of a rat model of depression: normalization by lithium . Int J Neuropsychopharmacol 18 : pyv002 . 25618407 

  103. Wechsler D ( 1997 ) Wechsler Memory Scale-Third Edition Manual . The Psychological Corporation: San Antonio, TX. 

  104. Wechsler D ( 1981 ) Manual for the Wechsler Adult Intelligence Scale-Revised . Psychological Corporation: New York. 

  105. Wolkowitz OM, Mellon SH, Lindqvist D, Epel ES, Blackburn EH, Lin J et al ( 2015 ). PBMC telomerase activity, but not leukocyte telomere length, correlates with hippocampal volume in major depression . Psychiatry Res 232 : 58 –64. 25773002 

  106. Yaffe K, Lindquist K, Kluse M, Cawthon R, Harris T, Hsueh WC et al ( 2011 ). Telomere length and cognitive function in community-dwelling elders: findings from the Health ABC Study . Neurobiol Aging 32 : 2055 –2060. 20031273 

  107. Young RC, Biggs JT, Ziegler VE, Meyer DA ( 1978 ). A rating scale for mania: reliability, validity and sensitivity . Br J Psychiatry 133 : 429 –435. 728692 

  108. Yu WY, Chang HW, Lin CH, Cho CL ( 2008 ). Short telomeres in patients with chronic schizophrenia who show a poor response to treatment . J Psychiatry Neurosci 33 : 244 –247. 18592039 

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