$\require{mediawiki-texvc}$

연합인증

연합인증 가입 기관의 연구자들은 소속기관의 인증정보(ID와 암호)를 이용해 다른 대학, 연구기관, 서비스 공급자의 다양한 온라인 자원과 연구 데이터를 이용할 수 있습니다.

이는 여행자가 자국에서 발행 받은 여권으로 세계 각국을 자유롭게 여행할 수 있는 것과 같습니다.

연합인증으로 이용이 가능한 서비스는 NTIS, DataON, Edison, Kafe, Webinar 등이 있습니다.

한번의 인증절차만으로 연합인증 가입 서비스에 추가 로그인 없이 이용이 가능합니다.

다만, 연합인증을 위해서는 최초 1회만 인증 절차가 필요합니다. (회원이 아닐 경우 회원 가입이 필요합니다.)

연합인증 절차는 다음과 같습니다.

최초이용시에는
ScienceON에 로그인 → 연합인증 서비스 접속 → 로그인 (본인 확인 또는 회원가입) → 서비스 이용

그 이후에는
ScienceON 로그인 → 연합인증 서비스 접속 → 서비스 이용

연합인증을 활용하시면 KISTI가 제공하는 다양한 서비스를 편리하게 이용하실 수 있습니다.

Renal tubular damage caused by cylindrospermopsin (cyanotoxin) in mice

Toxicology letters, v.286, 2018년, pp.89 - 95  

Moraes, A.C.N. (Corresponding author at: 373 Carlos Chagas Filho Avenue, Cidade Universitá) ,  Magalhães, V.F. (ria, Ilha do Fundã)

Abstract AI-Helper 아이콘AI-Helper

Abstract Cylindrospermopsin (CYN) is a cyanotoxin and a hydrophilic alkaloid of 415 Da. The principal effect of CYN is the inhibition of protein synthesis, and it can damage various organs. Studies have demonstrated that the kidney is the most affected organ. CYN has played roles in at least two po...

주제어

참고문헌 (39)

  1. Physiol. Rev. Auckland 73 1 1993 10.1152/physrev.1993.73.1.1 Interstitial lymphatic mechanisms in the control of extracellular fluid volume 

  2. Science Brown 232 April (4746) 34 1986 10.1126/science.3513311 A receptor-mediated pathway for cholesterol homeostasis 

  3. Med. J. Aust. Byth 2 40 1980 10.5694/j.1326-5377.1980.tb131814.x Palm island mystery disease 

  4. Clin. Chim. Acta Da Silva Melo 373 88 2006 10.1016/j.cca.2006.05.006 Evaluation of renal enzymuria and cellular excretion as an marker of acute nephrotoxicity due to an overdose of paracetamol in Wistar rats 

  5. Environ. Toxicol. Eagleshaw 14 151 1999 10.1002/(SICI)1522-7278(199902)14:1<151::AID-TOX19>3.0.CO;2-D Use of HPLC-MS/MS to monitor cylindrospermopsin, a blue-green algal toxin, for public health purposes 

  6. Environ. Toxicol. Falconer 14 1 143 1999 10.1002/(SICI)1522-7278(199902)14:1<143::AID-TOX18>3.0.CO;2-H Hepatic and renal toxicity of the blue-green alga (cyanobacterium) Cylindrospermopsis raciborskii in male Swiss albino mice 

  7. Curr. Opin. Nephrol. Hypertens. Farris 21 289 2012 10.1097/MNH.0b013e3283521cfa Renal interstitial fibrosis: mechanisms and evaluation 

  8. Verh. Int. Verein. Limnol. Gorham 15 796 1964 Isolation and culture of toxic strains of Anabaena flos-aquae (Lyngb.) de Bréb 

  9. Food Chem. Toxicol. Gumbleton 26 37 1988 10.1016/0278-6915(88)90039-7 Dose-response and time-response biochemical and histological study of potassium dichromate-induced nephrotoxicity in the rat 

  10. Adv. Cancer Res. Hanigan 122 103 2014 10.1016/B978-0-12-420117-0.00003-7 Gamma-glutamyl transpeptidase: redox regulation and drug resistance 

  11. Toxicon Harada 32 73 1994 10.1016/0041-0101(94)90023-X Isolation of cylindrospermopsin from a cyanobacterium Umezakia natans and its screening method 

  12. Appl. Environ. Microbiol. Hawkins 50 1292 1985 10.1128/AEM.50.5.1292-1295.1985 Severe hepatotoxicity caused by the tropical cyanobacterium (blue-green alga) Cylindrospermopsis raciborskii (Woloszynska) Seenaya and Subba Raju isolated from a domestic water supply reservoir 

  13. Environ. Toxicol. Humpage 18 2 94 2003 10.1002/tox.10104 Oral toxicity of the cyanobacterial toxin cylindrospermopsin in male swiss albino mice: determination of No observed adverse effect level for deriving a drinking water guideline value 

  14. Am. J. Physiol. Jerome 267 H1329 1994 Leukocyte adhesion, edema, and development of postischemic capillary no-reflow 

  15. J. Clin. Chem. Biochem. Jung 25 April (11) 823 1987 Urinary enzymes in research and in clinical medicine. Report on a symposium of the Humboldt-Universitat Berlin and the Bezirkrankenhaus Frankfurt/Oder in Frankfurt/Oder, 22-25 

  16. FEMS Microbiol. Ecol. Kaebernick 35 1 2001 10.1111/j.1574-6941.2001.tb00782.x Ecological and molecular investigations of cyanotoxin production 

  17. Biochem. J. Leathwood 114 197 1969 10.1042/bj1140197 The excretion of lactate dehydrogenase in human urine after the ingestion of aspirine 

  18. Lab. Invest. Lebargy 62 June (6) 731 1990 Localization by in situ hybridization of gamma-glutamyl transpeptidase mRNA in the rat kidney using 35S-labeled RNA probes 

  19. Rev. Radic. Res. Lee 38 6 535 2004 Is serum gamma glutamyltransferase a marker of oxidative stress? 

  20. Proc. Natl. Acad. Sci. U. S. A. Lieberman 93 15 7923 1996 10.1073/pnas.93.15.7923 Growth retardation and cysteine deficiency in gamma-glutamyl transpeptidase-deficient mice 

  21. Toxicon Lowe 59 6 601 2012 10.1016/j.toxicon.2012.02.003 Single sublethal dose of microcystin-LR is responsible for different alterations in biochemical, histological and physiological renal parameters 

  22. J. Biol. Chem. Lowry 193 265 1951 10.1016/S0021-9258(19)52451-6 Protein measurement with the Folinphenol reagent 

  23. Biochim. Biophys. Acta Lu 1830 3143 2013 10.1016/j.bbagen.2012.09.008 Glutathione synthesis 

  24. Chembiochem Mazmouz 12 858 2011 10.1002/cbic.201000726 The last step of the biosynthesis of the cyanotoxins cylindrospermopsin and 7-epi-cylindrospermopsin is catalysed by CyrI, a 2-oxoglutarate-dependent iron oxygenase 

  25. Endocytosis Phys. Rev. Mukherjee 77 July (3) 759 1997 

  26. Environ. Toxicol. Norris 16 498 2001 10.1002/tox.10008 Distribution of 14C cylindrospermopsin in vivo in the mouse 

  27. Trends Mol. Med. Patrakka 13 396 2007 10.1016/j.molmed.2007.06.006 Nephrin - a unique structural and signaling protein of the kidney filter 

  28. Toxicon Preussel 47 156 2006 10.1016/j.toxicon.2005.10.013 First report on cylindrospermopsin producing Aphanizomenon flos-aquae (Cyanobacteria) isolated from two German lakes 

  29. Hum. Mol. Genet. Putaala 10 1 2001 10.1093/hmg/10.1.1 The murine nephrin gene is specifically expressed in kidney, brain and pancreas: inactivation of the gene leads to massive proteinuria and neonatal death 

  30. Biochem. Biophys. Res. Commun. Runnegar 201 235 1994 10.1006/bbrc.1994.1694 Role of glutathione in the toxicity of a novel cyanobacterial alkaloid cylindrospermopsin in cultured rat hepatocytes 

  31. Biochem. Pharmacol. Runnegar 49 219 1995 10.1016/S0006-2952(94)00466-8 Inhibition of reduced glutathione synthesis by cyanobacterial alkaloid cylindrospermopsin in cultured rat hepatocytes 

  32. Kidney Int. Schmidt 9 233 1976 10.1038/ki.1976.26 Sites of enzyme activity along the nephron 

  33. Environ. Toxicol. Seawright 14 135 1999 10.1002/(SICI)1522-7278(199902)14:1<135::AID-TOX17>3.0.CO;2-L The oral toxicity for mice of the tropical cyanobacterium Cylindrospermopsis raciborskii (Woloszynska) 

  34. Fundam. Appl. Toxicol. Stonard 9 339 1987 10.1016/0272-0590(87)90056-X Urinary enzymes and protein patterns as indicators of injury to different regions of the kidney 

  35. Toxicon Terao 32 833 1994 10.1016/0041-0101(94)90008-6 Electron microscopic studies on experimental poisoning in mice induced by cylindrospermopsin isolated from blue-green alga Umezakia natans 

  36. Am. J. Physiol. Tojo 263 October (4 pt. 2) F601 1992 Intrarenal handling of proteins in rats using fractional micropuncture technique 

  37. J. Biol. Chem. Vieyra 261 528 4347 1986 Comparison between calcium transport and adenosine triphosphatase activity in membrane vesicles derived from rabbit kidney proximal tubules 

  38. Water Res. Welker 36 4659 2002 10.1016/S0043-1354(02)00194-X HPLC-PDA detection of cylindrospermopsin - opportunities and limits 

  39. Methods Enzymol. Zhang 401 468 2005 10.1016/S0076-6879(05)01028-1 ©-Glutamyl transpeptidase in glutathione biosynthesis 

관련 콘텐츠

저작권 관리 안내
섹션별 컨텐츠 바로가기

AI-Helper ※ AI-Helper는 오픈소스 모델을 사용합니다.

AI-Helper 아이콘
AI-Helper
안녕하세요, AI-Helper입니다. 좌측 "선택된 텍스트"에서 텍스트를 선택하여 요약, 번역, 용어설명을 실행하세요.
※ AI-Helper는 부적절한 답변을 할 수 있습니다.

선택된 텍스트

맨위로