[논문]COLLAGEN COUPLED WITH HYALURONIC: SYNTHESIS AND SOFT TISSUE FILLER APPLICATION

Tung, Kwang Yi; Lee, Ming Wei

doi:10.4015/s101623721000216x

COLLAGEN COUPLED WITH HYALURONIC: SYNTHESIS AND SOFT TISSUE FILLER APPLICATION

Biomedical engineering : applications, basis and communications, v.22 no.5, 2010년, pp.401 - 407

Tung, Kwang Yi (Plastic Surgery, Mackay Memorial Hospital, No. 92, Sec. 2, Chung-Shan N. Rd., Taipei 104, Taiwan) , Lee, Ming Wei (School of Medical Laboratory and Biotechnology, Chung Shan Medical University, No. 110, Sec. 1, Jianguo N.Rd., Taichung City 402, Taiwan)

Abstract ▼ AI-Helper

Injectable filler, which is often applied in minimally invasive surgery, has been widely-used in facial rejuvenation. Because of its convenience, effective usage and less downtime after treatment for the patients, it becomes one of the most popular treatment methods at present. The currently available products containing collagen base have been proven to have much satisfactory safety and effectiveness, but one of its disadvantages is the lack of long-term volume persistence. We have previously prepared the reconstituted collagen fibrils with hyaluronic acid (HA) by modifying the fibril surface. This study is to evaluate the potential of these materials as injectable filler in vitro. A preparation of collagen fibrils with a diameter of 100-150 nm was used. The modification rate of HA on the fibril surface was 20%. In assessment of the biocompatibility, it was proven that the collagen fibril and HA-collagen fibril treated with 1-ethyl-3-(3-dimethylaminopropyl) carbodiimide (EDC) had no cytotoxicity or inhibitory actions. In interactions between these materials and cells, it was found that the existence of HA could improve the migration ability of L929 fibroblasts and breast cancer cells (MDA-MB 435s). In conclusion, collagen fibril and HA-collagen fibril have the potential to be developed into an injection as a soft tissue filler for biomedical applications.

참고문헌 (17)

Klein, Arnold W., Elson, Melvin L.. The History of Substances for Soft Tissue Augmentation. Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.], vol.26, no.12, 1096-1105.

상세보기
Sclafani, Anthony P., Romo III, Thomas, Parker, Andrew, McCormick, Steven A., Cocker, Rubina, Jacono, Andrew. Autologous Collagen Dispersion (Autologen) as a Dermal Filler : Clinical Observations and Histologic Findings. Archives of facial plastic surgery, vol.2, no.1, 48-52.

상세보기
KLIGMAN, ALBERT M., ARMSTRONG, ROSA C.. Histologic Response to Intradermal Zyderm and Zyplast (Glutaraldehyde Cross‐Linked) Collagen in Humans. The Journal of dermatologic surgery and oncology, vol.12, no.4, 351-357.

상세보기
J. Cell Sci. Schor S. L. 159 10.1242/jcs.41.1.159 41

상세보기
Pharm. Sci. Technolo. Today Glenn D. 42 1
Timkovich, Russell. Detection of the stable addition of carbodiimide to proteins. Analytical biochemistry, vol.79, no.1, 135-143.

상세보기
J. Biochem. Biophys. Methods Regina K. P. 33 32

상세보기
Wood, G. C.. The formation of fibrils from collagen solutions. 2. A mechanism for collagen-fibril formation. The Biochemical journal, vol.75, no.3, 598-605.

상세보기
Bertrand, Jany, Delpecht, B, Maingonnat, C, Bertrand, P, Picard, J. The Quantitation of Pleural Hyaluronic Acid by An Immunoenzymoassay. Annals of clinical biochemistry : an international journal of biochemistry in medicine, vol.27, no.2, 167-168.

상세보기
Biochem. J. Wood G. C. 586 75
Garg, A.K., Berg, R.A., Silver, F.H., Garg, H.G.. Effect of proteoglycans on type I collagen fibre formation. Biomaterials, vol.10, no.6, 413-419.

상세보기
Englert, Carsten, Blunk, Torsten, Müller, Rainer, von Glasser, Sabine Schulze, Baumer, Julia, Fierlbeck, Johann, Heid, Iris M, Nerlich, Michael, Hammer, Joachim. Bonding of articular cartilage using a combination of biochemical degradation and surface cross-linking. Arthritis research & therapy, vol.9, no.3, R47-R47.

상세보기
Biorheology Hsu S.-H. 17 44

상세보기
White, Daniel J, Puranen, Santeri, Johnson, Mark S, Heino, Jyrki. The collagen receptor subfamily of the integrins. The international journal of biochemistry & cell biology, vol.36, no.8, 1405-1410.

상세보기
J. of. Invest. Dermatol. Ahrens T. 93 116
Dermatol. Surg. Rzany B. 326 34

상세보기
10.1016/0076-6879(87)44176-1

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COLLAGEN COUPLED WITH HYALURONIC: SYNTHESIS AND SOFT TISSUE FILLER APPLICATION

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