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A review on Royal Jelly proteins and peptides

Journal of functional foods : the official journal of the International Society for Nutraceuticals & Functional Foods, v.44, 2018년, pp.255 - 264  

Ramanathan, Ajitha Nath Koomankode Ganapathi (Department of Biotechnology, University of Kerala, Karyavattom, Thiruvananthapuram 695581, Kerala, India) ,  Nair, Ananthakrishnan Jayakumaran (Department of Biotechnology, University of Kerala, Karyavattom, Thiruvananthapuram 695581, Kerala, India) ,  Sugunan, Vetha Sundaram (Department of Zoology, University College, Thiruvananthapuram 695034, Kerala, India)

Abstract AI-Helper 아이콘AI-Helper

Abstract Royal Jelly (RJ) is a nutrient rich substance secreted by the hypopharyngeal glands of young worker bees. Owing to the exceptional biological properties, RJ is used in pharmaceutical, food and cosmetics industries. Several studies vouch that RJ has anti-ageing, antibacterial, anti-fatigue,...

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참고문헌 (112)

  1. Journal of Apicultural Research Albert 46 99 2007 MRJP9, an ancient protein of the honey bee MRJP family with non-nutritional function 

  2. Journal of Molecular Evolution Albert 49 290 1999 10.1007/PL00006551 The family of major royal jelly proteins and its evolution 

  3. Insect Biochemistry and Molecular Biology Albert 29 427 1999 10.1016/S0965-1748(99)00019-3 Molecular characterization of MRJP3, highly polymorphic protein of honey bee (Apis mellifera) royal jelly 

  4. Bulletin of University of Agricultural Sciences and Veterinary Medicine Cluj-Napoca Animal Science and Biotechnologies Bărnutiu 68 85 2011 Antimicrobial compounds of royal jelly 

  5. Apidologie Beye 29 3 255 1998 10.1051/apido:19980305 A simple, non-radioactive DNA fingerprinting method for identifying patrilines in honey bee colonies 

  6. Journal of agricultural and food chemistry Biilikova 58 15 8776 2010 10.1021/jf101583s New criterion for evaluation of honey: Quantification of royal jelly protein apalbumin 1 in honey by ELISA 

  7. FEBS Letters Bilikova 528 125 2002 10.1016/S0014-5793(02)03272-6 Apisimin, a new serine-valine-rich peptide from honey bee (Apis mellifera L.) royal jelly: Purification and molecular characterization 

  8. Proteomics Bilikova 9 8 2131 2009 10.1002/pmic.200800705 Towards functional proteomics of minority component of honeybee royal jelly: The effect of post-translational modifications on the antimicrobial activity of apalbumin2 

  9. Apidologie Bilikova 32 275 2001 10.1051/apido:2001129 Isolation of a peptide fraction from honey bee royal jelly as a potential antifoulbrood factor 

  10. Clinical & Experimental Allergy Blank 42 976 2012 10.1111/j.1365-2222.2012.03966.x The major royal jelly proteins 8 and 9 (Api m 11) are glycosylated components of Apis mellifera venom with allergenic potential beyond carbohydrate-based reactivity 

  11. Lipids Bogdanov 3 8 2011 Royal jelly, bee brood: Composition, health, medicine: A review 

  12. Journal of Apicultural Research Brouwers 26 11 1987 10.1080/00218839.1987.11100729 Behavioural and physiological aspects of nurse bees in relation to the composition of larval food during caste differentiation in the honey bee 

  13. Nature Buttstedt 537 7621 E10 2016 10.1038/nature19349 Royalactin is not a royal making of a queen 

  14. Frontiers in Zoology Buttstedt 10 72 2013 10.1186/1742-9994-10-72 More than royal food-Major royal jelly protein genes in sexuals and workers of the honey bee Apis mellifera 

  15. Biological Reviews Buttstedt 89 255 2013 10.1111/brv.12052 Origin and function of the major royal jelly proteins of the honey bee (Apis mellifera) as members of the yellow gene family 

  16. Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular Biology Calabria 151 41 2008 10.1016/j.cbpb.2008.05.006 Identification of calmodulin-binding proteins in brain of worker honey bees 

  17. FEMS Microbiology Reviews Cereghino 24 1 45 2000 10.1111/j.1574-6976.2000.tb00532.x Heterologous protein expression in the methylotrophic yeast Pichia pastoris 

  18. Journal of Apicultural Science Chanchao 50 5 2006 Expression of α-glucosidase gene in hypopharyngeal glands of Eastern honey bee worker Apis cerana indica 

  19. Apidologie Cruz 42 252 2011 10.1007/s13592-011-0025-9 Calcium effect and pH-dependence on self-association and structural stability of the Apis mellifera major royal jelly protein 1 

  20. Experimental Gerontology Detienne 60 129 2014 10.1016/j.exger.2014.09.021 Royalactin extends lifespan of Caenorhabditis elegans through epidermal growth factor signaling 

  21. Biochemical and Biophysical Research Communications Drapeau 311 1 2003 10.1016/j.bbrc.2003.09.106 A novel hypothesis on the biochemical role of the Drosophila Yellow protein 

  22. Genome Research Drapeau 16 1385 2006 10.1101/gr.5012006 Evolution of the Yellow/Major Royal Jelly Protein family and the emergence of social behavior in honey bees 

  23. Molecular Biology and Evolution Ferguson 28 257 2011 10.1093/molbev/msq192 Evolution of the insect yellow gene family 

  24. Peptides Fontana 25 919 2004 10.1016/j.peptides.2004.03.016 Jelleines: A family of antimicrobial peptides from the Royal Jelly of honey bees (Apis mellifera) 

  25. Proceedings of the National Academy of Sciences Foret 109 4968 2012 10.1073/pnas.1202392109 DNA methylation dynamics, metabolic fluxes, gene splicing, and alternative phenotypes in honey bees 

  26. Microbiological Research Fratini 192 130 2016 10.1016/j.micres.2016.06.007 Royal Jelly: An Ancient remedy with remarkable antibacterial properties 

  27. Journal of Biological Chemistry Fujiwara 265 11333 1990 10.1016/S0021-9258(19)38596-5 A potent antibacterial protein in royal jelly. Purification and determination of the primary structure of royalisin 

  28. Medicine and Biology Funakoshi 127 85 1993 Proteolytic activity of royal jelly 

  29. 10.1155/2016/5040528 Furusawa, T., Arai, Y., Kato, K., & Ichihara, K. (2016). Quantitative Analysis of Apisin, a Major Protein Unique to Royal Jelly. Evidence-Based Complementary and Alternative Medicine, 2016. 

  30. Journal of Proteome Research Furusawa 7 3194 2008 10.1021/pr800061j Comprehensive royal jelly (RJ) proteomics using one-and two-dimensional proteomics platforms reveals novel RJ proteins and potential phospho/glycoproteins 

  31. Journal of Proteome Research Garcia 8 1464 2009 10.1021/pr800823r Proteomic analysis of honey bee brain upon ontogenetic and behavioral development 

  32. Journal of Apicultural Research Hanes 31 22 1992 10.1080/00218839.1992.11101256 Identification and partial characterization of the major royal jelly protein of the honey bee (Apis mellifera L.) 

  33. DNA Research Helbing 24 3 279 2017 10.1093/dnares/dsw064 Comparative analyses of the major royal jelly protein gene cluster in three Apis species with long amplicon sequencing 

  34. Nature Honey bee Genome Sequencing Consortium 443 931 2006 10.1038/nature05260 Insights into social insects from the genome of the honey bee Apis mellifera 

  35. Journal of Insect Physiology Hrassnigg 44 929 1998 10.1016/S0022-1910(98)00058-4 Adaptation of hypopharyngeal gland development to the brood status of honey bee (Apis mellifera L.) colonies 

  36. Insectes Sociaux Huang 36 264 1989 10.1007/BF02224880 Factors determining hypopharyngeal gland activity of worker honey bees (Apis mellifera L.) 

  37. Journal of Proteome Research Huo 15 9 3342 2016 10.1021/acs.jproteome.6b00526 Proteomic analysis reveals the molecular underpinnings of mandibular gland development and lipid metabolism in two lines of honey bees (Apis mellifera ligustica) 

  38. Journal of Chemical Technology and Biotechnology Ibarra-Herrera 89 941 2014 10.1002/jctb.4342 Recovery of major royal jelly protein 1 expressed in Pichia pastoris in aqueous two-phase systems 

  39. BMB Reports Imjongjirak 38 49 2005 10.5483/BMBRep.2005.38.1.049 Cloning, expression and genomic organization of genes encoding major royal jelly protein 1 and 2 of the honey bee (Apis cerana) 

  40. Section Cellular and Molecular Biology Judova 6 777 1998 Preparation of recombinant most abundant protein MRJP1 of royal jelly 

  41. Biologia Plantarum Judova 48 185 2004 10.1023/B:BIOP.0000033443.60872.f1 Transformation of tobacco plants with cDNA encoding honey bee royal jelly MRJP1 

  42. Nature Kamakura 473 478 2011 10.1038/nature10093 Royalactin induces queen differentiation in honey bees 

  43. Protein Expression and Purification Kamakura 45 2 307 2006 10.1016/j.pep.2005.08.004 A hypopharyngeal gland protein of the worker honeybee Apis mellifera L. enhances proliferation of primary-cultured rat hepatocytes and suppresses apoptosis in the absence of serum 

  44. Bioscience, Biotechnology, and Biochemistry Kamakura 65 277 2001 10.1271/bbb.65.277 Storage-dependent degradation of 57-kDa protein in royal jelly: A possible marker for freshness 

  45. Biochemical and Biophysical Research Communications Kamakura 282 865 2001 10.1006/bbrc.2001.4656 Fifty-seven-kDa protein in royal jelly enhances proliferation of primary cultured rat hepatocytes and increases albumin production in the absence of serum 

  46. Bioscience, biotechnology, and Biochemistry Kimura 67 2055 2003 10.1271/bbb.67.2055 350-kDa royal jelly glycoprotein (apisin), which stimulates proliferation of human monocytes, bears the β1-3galactosylated N-glycan: Analysis of the N-glycosylation site 

  47. Bioscience, Biotechnology, and Biochemistry Kimura 60 12 2099 1996 10.1271/bbb.60.2099 N-linked sugar chain of 55-kDa royal jelly glycoprotein 

  48. Journal of Apicultural Research Klaudiny 33 105 1994 10.1080/00218839.1994.11100857 Molecular cloning of two cDNAs from the head of the nurse honey bee (Apis mellifera L.) for coding related proteins of royal jelly 

  49. Apidologie Klaudiny 25 596 1994 10.1051/apido:19940610 New approach to the study of division of labour in the honey bee colony (Apis mellifera L.) 

  50. Apidologie Knecht 21 457 1990 10.1051/apido:19900507 Patterns of larval food production by hypopharyngeal glands in adult worker honey bees 

  51. Bioscience, Biotechnology, and Biochemistry Kohno 68 138 2004 10.1271/bbb.68.138 Royal jelly inhibits the production of proinflammatory cytokines by activated macrophages 

  52. Journal of Biochemistry Kubo 119 291 1996 10.1093/oxfordjournals.jbchem.a021237 Change in the Expression of Hypopharyngeal-Gland Proteins of the Worker Honey bees (Apis mellifera L.) with Age and/or Role 

  53. Science Kucharski 319 1827 2008 10.1126/science.1153069 Nutritional control of reproductive status in honey bees via DNA methylation 

  54. Naturwissenschaften Kucharski 85 343 1998 10.1007/s001140050512 A royal jelly protein is expressed in a subset of Kenyon cells in the mushroom bodies of the honey bee brain 

  55. Annual Review of Biochemistry Kukuruzinska 56 915 1987 10.1146/annurev.bi.56.070187.004411 Protein glycosylation in yeast 

  56. Apicoltura Lercker 8 27 1993 Caratterizzazione dei principali costituenti della gelatina reale 

  57. Journal Allergy & Clinical Immunology Leung 96 1004 1997 10.1016/S0091-6749(95)70242-3 Royal jelly-induced asthma and anaphylaxis: Clinical characteristics and immunological correlations 

  58. Journal of Agricultural and Food Chemistry Li 55 8411 2007 10.1021/jf0717440 Proteomic analysis of royal jelly from three strains of western honey bees (Apis mellifera) 

  59. BMC Genomics Liu 15 744 2014 10.1186/1471-2164-15-744 Transcriptome differences in the hypopharyngeal gland between Western Honey bees (Apis mellifera) and Eastern Honey bees (Apis cerana) 

  60. Sociobiology Liu 62 412 2015 10.13102/sociobiology.v62i3.760 Quantitative analysis of the genes affecting development of the hypopharyngeal gland in honey bees (Apis mellifera L.) 

  61. 10.1109/iCBEB.2012.114 Ma, X., Yang, S., Jin, W., Zhao, Y., Ma, H., & Luan, W. (2012). Construction of a recombinant major royal jelly protein 1 (MRJP1) expression vector for mammary gland-specific expression. In Biomedical Engineering and Biotechnology (iCBEB), 2012 International Conference on (pp. 988-991). IEEE. 

  62. International Immunopharmacology Majtán 6 269 2006 10.1016/j.intimp.2005.08.014 The immunostimulatory effect of the recombinant apalbumin 1-major honey bee royal jelly protein - on TNFα release 

  63. Experimental Dermatology Majtan 19 e73 2009 10.1111/j.1600-0625.2009.00994.x Effect of honey and its major royal jelly protein 1 on cytokine and MMP-9 mRNA transcripts in human keratinocytes 

  64. Gene Malecová 303 165 2003 10.1016/S0378-1119(02)01174-5 Honey bee (Apis mellifera L.) mrjp gene family: Computational analysis of putative promoters and genomic structure of mrjp1, the gene coding for the most abundant protein of larval food 

  65. Biochemistry Mandacaru 56 11 1645 2017 10.1021/acs.biochem.7b00020 Characterizing the structure and oligomerization of major royal jelly protein 1 (MRJP1) by mass spectrometry and complementary biophysical tools 

  66. PloS one Moriyama 10 5 e0119169 2015 10.1371/journal.pone.0119169 Heat resistant characteristics of major royal jelly protein 1 (MRJP1) oligomer 

  67. Developmental Biology Nash 48 336 1976 10.1016/0012-1606(76)90095-6 Patterns of pigmentation color states regulated by the y locus in Drosophila melanogaster 

  68. Food Chemistry Nozaki 134 2332 2012 10.1016/j.foodchem.2012.03.106 A rapid method to isolate soluble royal jelly proteins 

  69. European Journal of Biochemistry Ohashi 249 797 1997 10.1111/j.1432-1033.1997.t01-1-00797.x Change in the Mode of Gene Expression of the Hypopharyngeal Gland Cells with an Age-dependent Role Change of the Worker Honey bee Apis mellifera L 

  70. Zoological Science Ohashi 17 8 1089 2000 10.2108/zsj.17.1089 Functional flexibility of the honey bee hypopharyngeal gland in a dequeened colony 

  71. Life Sciences Okamoto 73 2029 2003 10.1016/S0024-3205(03)00562-9 Major royal jelly protein 3 modulates immune responses in vitro and in vivo 

  72. Bee World Örösi-Ṕ l 38 3 70 1957 10.1080/0005772X.1957.11094979 The role of the mandibular glands of the honey bee 

  73. Scientific Papers Animal Science and Biotechnologies Pavel 44 108 2011 Biological activities of royal jelly-review 

  74. BMJ. British Medical Journal Peacock 311 1472 1995 10.1136/bmj.311.7018.1472a Respiratory distress and royal jelly 

  75. Toxicon Peiren 52 72 2008 10.1016/j.toxicon.2008.05.003 Proteomic analysis of the honey bee worker venom gland focusing on the mechanisms of protection against tissue damage 

  76. Journal of Insect Physiology Peixoto 55 671 2009 10.1016/j.jinsphys.2009.05.005 Identification of major royal jelly proteins in the brain of the honey bee Apis mellifera 

  77. Journal of Proteome Research Qi 14 4647 2015 10.1021/acs.jproteome.5b00530 Phosphoproteomic analysis of protein phosphorylation networks in the hypopharyngeal gland of honey bee workers (Apis mellifera ligustica) 

  78. Biochemistry (Moscow) Qu 73 676 2008 10.1134/S0006297908060072 Proteomic characterization of royal jelly proteins in Chinese (Apis cerana cerana) and European (Apis mellifera) honey bees 

  79. Journal of Functional Foods Ramadan 4 39 2012 10.1016/j.jff.2011.12.007 Bioactive compounds and health-promoting properties of royal jelly: A review 

  80. Vitamins & Hormones Rembold 23 359 1966 10.1016/S0083-6729(08)60385-4 Biologically active substances in royal jelly 

  81. Tropical Biomedicine Rosmilah 25 243 2008 Characterization of major allergens of royal jelly Apis mellifera 

  82. Journal of ApiProduct and ApiMedical Science Sabatini 1 1 2009 10.3896/IBRA.4.01.1.04 Quality and standardisation of royal jelly 

  83. Journal of Agricultural and Food Chemistry Sano 52 15 2004 10.1021/jf030340e Characterization of royal jelly proteins in both Africanized and European honey bees (Apis mellifera) by two-dimensional gel electrophoresis 

  84. Insect Biochemistry and Molecular Biology Santos 35 85 2005 10.1016/j.ibmb.2004.10.003 Profiling the proteome complement of the secretion from hypopharyngeal gland of Africanized nurse-honey bees (Apis mellifera L.) 

  85. Proteomics Scarselli 5 769 2005 10.1002/pmic.200401149 Towards royal jelly proteome 

  86. Cellular and Molecular Life Sciences Schmitzova 54 1020 1998 10.1007/s000180050229 A family of major royal jelly proteins of the honey bee Apis mellifera L 

  87. Analytical and Bioanalytical Chemistry Schönleben 389 1087 2007 10.1007/s00216-007-1498-2 Proteome analysis of Apis mellifera royal jelly 

  88. Journal of Zhejiang University Science B Shen 16 155 2015 10.1631/jzus.B1400223 Determination of royal jelly freshness by ELISA with a highly specific anti-apalbumin 1, major royal jelly protein 1 antibody 

  89. Journal of Agricultural and Food Chemistry Shen 58 9190 2010 10.1021/jf1007133 Expression of recombinant AccMRJP1 protein from royal jelly of Chinese Honey bee in Pichia pastoris and its proliferation activity in an insect cell line 

  90. International Journal of Industrial Entomology Shinkhede 18 139 2009 Royal Jelly Protein and Lipid Composition in Apis cerana indica F 

  91. Journal of Apicultural Research Simpson 7 29 1968 10.1080/00218839.1968.11100184 Invertase in the hypopharyngeal glands of the honey bee 

  92. Chemical Papers-Slovak Academy of Sciences Simuth 52 311 1998 Molecular and functional properties of royal jelly proteins 

  93. Apidologie Šimúth 32 69 2001 10.1051/apido:2001112 Some properties of the main protein of honey bee (Apis mellifera) royal jelly 

  94. Apimondia Šimuth 24 656 2003 Royal Jelly proteins as a tool for development of functional ingredients for health 

  95. Journal of Agricultural and Food Chemistry Šimúth 52 2154 2004 10.1021/jf034777y Immunochemical approach to detection of adulteration in honey: Physiologically active royal jelly protein stimulating TNF-α release is a regular component of honey 

  96. Snodgrass 1984 Anatomy of the honey bee 

  97. Apidologie Su 36 389 2005 10.1051/apido:2005026 Molecular cloning and analysis of four cDNAs from the heads of Apis cerana cerana nurse honey bees coding for major royal jelly proteins 

  98. 10.1155/2010/181025 Suwannapong, G., Chaiwongwattanakul, S., & Benbow, M. E. (2010). Histochemical comparison of the hypopharyngeal gland in Apis cerana Fabricius, 1793 workers and Apis mellifera Linnaeus, 1758 workers. Psyche: A Journal of Entomology. 

  99. Contact Dermatitis Takahashi 9 452 1983 10.1111/j.1600-0536.1983.tb04462.x Contact dermatitis due to honey bee royal jelly 

  100. Proteomics Tamura 9 5534 2009 10.1002/pmic.200900541 Molecular characteristics and physiological functions of major royal jelly protein 1 oligomer 

  101. Food Chemistry Tamura 114 1491 2009 10.1016/j.foodchem.2008.11.058 Estimation and characterisation of major royal jelly proteins obtained from the honey bee Apis merifera 

  102. Journal of Agricultural and Food Chemistry Tao 56 9464 2008 10.1021/jf8018497 Expression of apalbumin1 of Apis cerana cerana in the larvae of silkworm, Bombyx mori 

  103. Clinical & Experimental Allergy Thien 26 216 1996 10.1111/j.1365-2222.1996.tb00082.x Asthma and anaphylaxis induced by royal jelly 

  104. Biotechnology Techniques Watanabe 10 12 959 1996 10.1007/BF00180402 Growth stimulation with honey royal jelly DIII protein of human lymphocytic cell lines in a serum-free medium 

  105. Cytotechnology Watanabe 26 1 23 1998 10.1023/A:1007928408128 Stimulation of cell growth in the U-937 human myeloid cell line by honey royal jelly protein 

  106. BMC Genomics Xia 7 1 195 2006 10.1186/1471-2164-7-195 Identification and analysis of YELLOW protein family genes in the silkworm, Bombyx mori 

  107. Journal of Agricultural and Food Chemistry Xin 64 29 5803 2016 10.1021/acs.jafc.6b00514 Supplementation with major royal-jelly proteins increases lifespan, feeding, and fecundity in Drosophila 

  108. Xue 181 2017 Bee products-chemical and biological properties Chemical composition of royal jelly 

  109. Journal of Gastroenterology and Hepatology Yonei 12 495 1997 10.1111/j.1440-1746.1997.tb00472.x Case report: Haemorrhagic colitis associated with royal jelly intake 

  110. Journal of Zhejiang University (Agriculture and Life Sciences) Zhang 36 2 119 2010 Cloning of royal jelly AccMRJP1 gene from Apis cerana cerana and its expression in Escherichia coli 

  111. Journal of Proteomics Zhang 75 5327 2012 10.1016/j.jprot.2012.06.008 Towards posttranslational modification proteome of royal jelly 

  112. Apidologie Zheng 2010 Changes in composition of royal jelly harvested at different times: Consequences for quality standards 

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