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Disease models & mechanisms : DMM, v.11 no.6, 2018년, pp.dmm032706 -
Vannocci, Tommaso (Basic and Clinical Neuroscience, Maurice Wohl Institute, King's College London , 5 Cutcombe Road , London SE5 9RT , UK) , Notario Manzano, Roberto (Basic and Clinical Neuroscience, Maurice Wohl Institute, King's College London , 5 Cutcombe Road , London SE5 9RT , UK) , Beccalli, Ombretta (Division of Neuroscience, Vita-Salute San Raffaele University and IRCCS San Raffaele Scientific Institute , 20132 Milan , Italy) , Bettegazzi, Barbara (Division of Neuroscience, Vita-Salute San Raffaele University and IRCCS San Raffaele Scientific Institute , 20132 Milan , Italy) , Grohovaz, Fabio (Division of Neuroscience, Vita-Salute San Raffaele University and IRCCS San Raffaele Scientific Institute , 20132 Milan , Italy) , Cinque, Gianfelice (Department of Physical Chemistry and Electrochemistry, Diamond House, Harwell Science and Innovation Campus , Didcot OX11 0DE , UK) , de Riso, Antonio (Hypha Discovery Ltd , London , UK) , Quaroni, Luca (Department of Physical Chemis) , Codazzi, Franca , Pastore, Annalisa
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ABSTRACTThe neurodegenerative disease Friedreich's ataxia is caused by lower than normal levels of frataxin, an important protein involved in iron–sulfur (Fe-S) cluster biogenesis. An important step in designing strategies to treat this disease is to understand whether increasing the frataxin...
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