[논문]Characteristics of traditional Chinese medicine users and prescription analysis for pediatric atopic dermatitis: a population-based study

Chen, Yu-Chun; Lin, Yi-Hsuan; Hu, Sindy; Chen, Hsing-Yu

doi:10.1186/s12906-016-1158-1

Characteristics of traditional Chinese medicine users and prescription analysis for pediatric atopic dermatitis: a population-based study 원문보기

Bmc complementary and alternative medicine, v.16, 2016년, pp.173 -

Chen, Yu-Chun (Department of Medical Research and Education, National Yang-Ming University Hospital, I-Lan, Taiwan) , Lin, Yi-Hsuan (Division of Chinese Internal Medicine, Center for Traditional Chinese Medicine, Chang Gung Memorial Hospital, No. 123, Dinghu Rd., Gueishan Dist., Taoyuan City, 33378 Taiwan) , Hu, Sindy (School of Traditional Chinese Medicine, College of Medicine, Chang Gung University, Taoyuan, Taiwan) , Chen, Hsing-Yu (Division of Chinese Internal Medicine, Center for Traditional Chinese Medicine, Chang Gung Memorial Hospital, No. 123, Dinghu Rd., Gueishan Dist., Taoyuan City, 33378 Taiwan)

Abstract ▼ AI-Helper

BackgroundAtopic dermatitis among children is an important issue due to relapses and skin manifestations. Traditional Chinese medicine (TCM) is commonly used to treat children with atopic dermatitis. The aim of this study was to investigate the characteristics and TCM prescriptions of patients with atopic dermatitis using a nationwide database.MethodsChildren younger than 12 years of age diagnosed with atopic dermatitis, defined as ICD-9-CM codes 691.8 and 692.x, were identified from the database. Data on age, diagnosis codes, area of residence and use of corticosteroids of the TCM users were recorded. Association rule mining was used to analyze the prescriptions used for atopic dermatitis.ResultsWe identified 13,646 children with atopic dermatitis using TCM in 2007. Female gender (OR: 0.83 for male gender), adolescence (OR: 10.0, 95 % CI: 8.88–11.15) and allergic rhinitis (OR: 2.44, 95 % CI: 2.10–2.85) were associated with the use of TCM. Fewer of the TCM users were prescribed with corticosteroids (35.8 % of all TCM users), but the TCM users had a higher rate of long-term topical corticosteroid therapy (10.6 % for TCM users versus 2.0 % for those who did not use TCM). Chinese herbal medicine (CHM) was used by 93.7 % of all TCM users in 36,398 prescriptions. On average, 5.6 kinds of CHM were used in combination. The relationship between the CHMs constituted a network, in which Xiao-Feng-San was the core treatment for atopic dermatitis.ConclusionsIn this study, we described the characteristics of children with atopic dermatitis who use TCM in Taiwan. and identified the core CHM treatment. Further research on the safety and efficacy of this treatment are still needed.

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참고문헌 (39)

1. Bieber T Atopic dermatitis Ann Dermatol 2010 22 2 125 137 10.5021/ad.2010.22.2.125 20548901

상세보기
2. Berke R Singh A Guralnick M Atopic dermatitis: an overview Am Fam Physician 2012 86 1 35 42 22962911

상세보기
3. Flohr C Mann J New insights into the epidemiology of childhood atopic dermatitis Allergy 2014 69 1 3 16 10.1111/all.12270 24417229

상세보기
4. Barnes KC An update on the genetics of atopic dermatitis: scratching the surface in 2009 J Allergy Clin Immunol 2010 125 1 16 29 e11-11 10.1016/j.jaci.2009.11.008 20109730

상세보기
5. Boguniewicz M Leung DY Atopic dermatitis: a disease of altered skin barrier and immune dysregulation Immunol Rev 2011 242 1 233 246 10.1111/j.1600-065X.2011.01027.x 21682749

상세보기
6. Eyerich K Novak N Immunology of atopic eczema: overcoming the Th1/Th2 paradigm Allergy 2013 68 8 974 982 10.1111/all.12184 23889510

상세보기
7. Kawakami T Ando T Kimura M Wilson BS Kawakami Y Mast cells in atopic dermatitis Curr Opin Immunol 2009 21 6 666 678 10.1016/j.coi.2009.09.006 19828304

상세보기
8. Buys LM Treatment options for atopic dermatitis Am Fam Physician 2007 75 4 523 528 17323714

상세보기
9. Aubert-Wastiaux H Moret L Le Rhun A Fontenoy AM Nguyen JM Leux C Misery L Young P Chastaing M Danou N Topical corticosteroid phobia in atopic dermatitis: a study of its nature, origins and frequency Br J Dermatol 2011 165 4 808 814 10.1111/j.1365-2133.2011.10449.x 21671892

상세보기
10. Hengge UR Ruzicka T Schwartz RA Cork MJ Adverse effects of topical glucocorticosteroids J Am Acad Dermatol 2006 54 1 1 15 10.1016/j.jaad.2005.01.010 16384751

상세보기
11. Moghadam-Kia S Werth VP Prevention and treatment of systemic glucocorticoid side effects Int J Dermatol 2010 49 3 239 248 10.1111/j.1365-4632.2009.04322.x 20465658

상세보기
12. Gu S Yang AW Xue CC Li CG Pang C Zhang W Williams HC Chinese herbal medicine for atopic eczema Cochrane Database Syst Rev 2013 9 Cd008642 24018636
13. Tan HY Zhang AL Chen D Xue CC Lenon GB Chinese herbal medicine for atopic dermatitis: a systematic review J Am Acad Dermatol 2013 69 2 295 304 10.1016/j.jaad.2013.01.019 23759835

상세보기
14. Chen HY Lin YH Wu JC Chen YC Thien PF Chen TJ Yang SH Chen JL Lo SS Characteristics of pediatric traditional Chinese medicine users in Taiwan: a nationwide cohort study Pediatrics 2012 129 6 e1485 1492 10.1542/peds.2011-3008 22585761

상세보기
15. Cheng CL Kao YH Lin SJ Lee CH Lai ML Validation of the National Health Insurance Research Database with ischemic stroke cases in Taiwan Pharmacoepidemiol Drug Saf 2011 20 3 236 242 10.1002/pds.2087 21351304

상세보기
16. Chen Y-C Yeh H-Y Wu J-C Haschler I Chen T-J Wetter T Taiwan’s National Health Insurance Research Database: administrative health care database as study object in bibliometrics Scientometrics 2011 86 2 365 380 10.1007/s11192-010-0289-2

상세보기
17. Lin YH Chen YC Hu S Chen HY Chen JL Yang SH Identifying core herbal treatments for urticaria using Taiwan's nationwide prescription database J Ethnopharmacol 2013 148 2 556 562 10.1016/j.jep.2013.04.052 23684721

상세보기
18. Chen HY Lin YH Thien PF Chang SC Chen YC Lo SS Yang SH Chen JL Identifying core herbal treatments for children with asthma: implication from a chinese herbal medicine database in taiwan Evid Based Complement Alternat Med 2013 2013 125943 24066007

상세보기
19. Hua TC Hwang CY Chen YJ Chu SY Chen CC Lee DD Chang YT Wang WJ Liu HN The natural course of early-onset atopic dermatitis in Taiwan: a population-based cohort study Br J Dermatol 2014 170 1 130 135 10.1111/bjd.12603 23980909

상세보기
20. Robinson CL Baumann LM Romero K Combe JM Gomez A Gilman RH Cabrera L Gonzalvez G Hansel NN Wise RA Effect of urbanisation on asthma, allergy and airways inflammation in a developing country setting Thorax 2011 66 12 1051 1057 10.1136/thx.2011.158956 21730351

상세보기
21. Hughes R Ward D Tobin AM Keegan K Kirby B The use of alternative medicine in pediatric patients with atopic dermatitis Pediatr Dermatol 2007 24 2 118 120 10.1111/j.1525-1470.2007.00355.x 17461804

상세보기
22. Chen HY Lin YH Su IH Chen YC Yang SH Chen JL Investigation on Chinese herbal medicine for primary dysmenorrhea: Implication from a nationwide prescription database in Taiwan Complement Ther Med 2014 22 1 116 125 10.1016/j.ctim.2013.11.012 24559826

상세보기
23. Leung TF Ko FW-s Wong GW-k Roles of pollution in the prevalence and exacerbations of allergic diseases in Asia J Allergy Clin Immunol 2012 129 1 42 47 10.1016/j.jaci.2011.11.031 22196523

상세보기
24. Hon KL Leung TF Ng PC Lam MC Kam WY Wong KY Lee KC Sung YT Cheng KF Fok TF Efficacy and tolerability of a Chinese herbal medicine concoction for treatment of atopic dermatitis: a randomized, double-blind, placebo-controlled study Br J Dermatol 2007 157 2 357 363 10.1111/j.1365-2133.2007.07941.x 17501956

상세보기
25. Jiang M Lu C Zhang C Yang J Tan Y Lu A Chan K Syndrome differentiation in modern research of traditional Chinese medicine J Ethnopharmacol 2012 140 3 634 642 10.1016/j.jep.2012.01.033 22322251

상세보기
26. Hon KL Ma KC Wong Y Leung TF Fok TF A survey of traditional Chinese medicine use in children with atopic dermatitis attending a paediatric dermatology clinic J Dermatolog Treat 2005 16 3 154 157 10.1080/09546630510038938 16096181

상세보기
27. Chan BC Hon KL Leung PC Sam SW Fung KP Lee MY Lau HY Traditional Chinese medicine for atopic eczema: PentaHerbs formula suppresses inflammatory mediators release from mast cells J Ethnopharmacol 2008 120 1 85 91 10.1016/j.jep.2008.07.034 18725279

상세보기
28. Cheng HM Chiang LC Jan YM Chen GW Li TC The efficacy and safety of a Chinese herbal product (Xiao-Feng-San) for the treatment of refractory atopic dermatitis: a randomized, double-blind, placebo-controlled trial Int Arch Allergy Immunol 2011 155 2 141 148 10.1159/000318861 21196758

상세보기
29. Shichijo K Saito H Effect of Chinese herbal medicines and disodium cromoglycate on IgE-dependent histamine release from mouse cultured mast cells Int J Immunopharmacol 1997 19 11-12 677 682 10.1016/S0192-0561(97)00097-0 9669208

상세보기
30. Akamatsu H Asada Y Horio T Inhibitory effect of shofu-san, a Japanese kampo medicine, on neutrophil functions in vitro Am J Chin Med 1998 26 1 57 64 10.1142/S0192415X98000087 9592594

상세보기
31. Gao XK Fuseda K Shibata T Tanaka H Inagaki N Nagai H Kampo medicines for mite antigen-induced allergic dermatitis in NC/Nga Mice Evid Based Complement Alternat Med 2005 2 2 191 199 10.1093/ecam/neh077 15937560

상세보기
32. Jiang S Nakano Y Rahman MA Yatsuzuka R Kamei C Effects of a Dictamnus dasycarpus T. extract on allergic models in mice Biosci Biotechnol Biochem 2008 72 3 660 665 10.1271/bbb.70050 18323651

상세보기
33. Kim H Kim M Kim H Lee GS An WG Cho SI Anti-inflammatory activities of Dictamnus dasycarpus Turcz., root bark on allergic contact dermatitis induced by dinitrofluorobenzene in mice J Ethnopharmacol 2013 149 2 471 477 10.1016/j.jep.2013.06.055 23850712

상세보기
34. Xu MZ Lee WS Han JM Oh HW Park DS Tian GR Jeong TS Park HY Antioxidant and anti-inflammatory activities of N-acetyldopamine dimers from Periostracum Cicadae Bioorg Med Chem 2006 14 23 7826 7834 10.1016/j.bmc.2006.07.063 16919462

상세보기
35. Matsuda H Dai Y Ido Y Yoshikawa M Kubo M Studies on kochiae fructus. IV. Anti-allergic effects of 70 % ethanol extract and its component, momordin Ic from dried fruits of Kochia scoparia L Biol Pharm Bull 1997 20 11 1165 1170 10.1248/bpb.20.1165 9401725

상세보기
36. Han J Lv QY Jin SY Zhang TT Jin SX Li XY Yuan HL Comparison of anti-bacterial activity of three types of di-O-caffeoylquinic acids in Lonicera japonica flowers based on microcalorimetry Chin J Nat Med 2014 12 2 108 113 24636060
37. Qu H Zhang Y Wang Y Li B Sun W Antioxidant and antibacterial activity of two compounds (forsythiaside and forsythin) isolated from Forsythia suspensa J Pharm Pharmacol 2008 60 2 261 266 10.1211/jpp.60.2.0016 18237475

상세보기
38. Ong PY Ohtake T Brandt C Strickland I Boguniewicz M Ganz T Gallo RL Leung DY Endogenous antimicrobial peptides and skin infections in atopic dermatitis N Engl J Med 2002 347 15 1151 1160 10.1056/NEJMoa021481 12374875

상세보기
39. Scheid V Ward T Tuffrey V Comparing TCM textbook descriptions of menopausal syndrome with the lived experience of London women at midlife and the implications for Chinese medicine research Maturitas 2010 66 4 408 416 10.1016/j.maturitas.2010.03.021 20444560

상세보기

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Characteristics of traditional Chinese medicine users and prescription analysis for pediatric atopic dermatitis: a population-based study 원문보기

Abstract ▼ AI-Helper

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