최소 단어 이상 선택하여야 합니다.
최대 10 단어까지만 선택 가능합니다.
다음과 같은 기능을 한번의 로그인으로 사용 할 수 있습니다.
NTIS 바로가기Journal of toxicology and environmental health. Part B, Critical reviews, v.21 no.1, 2018년, pp.8 - 23
Choi, Seul Min (Division of Toxicology, College of Pharmacy, Sungkyunkwan University, Gyeonggi-Do, Suwon, South Korea) , Roh, Tae Hyun (Division of Toxicology, College of Pharmacy, Sungkyunkwan University, Gyeonggi-Do, Suwon, South Korea) , Lim, Duck Soo (Division of Toxicology, College of Pharmacy, Sungkyunkwan University, Gyeonggi-Do, Suwon, South Korea) , Kacew, Sam (McLaughlin Centre for Population Health Risk Assessment, University of Ottawa, Ottawa, ON, Canada) , Kim, Hyung Sik (Division of Toxicology, College of Pharmacy, Sungkyunkwan University, Gyeonggi-Do, Suwon, South Korea) , Lee, Byung-Mu (Division of Toxicology, College of Pharmacy, Sungkyunkwan University, Gyeonggi-Do, Suwon, South Korea)
A risk assessment of benzalkonium chloride (BAC) was conducted based upon its toxicological profile and exposure evaluation. Since 1935, BAC has been used in a wide variety of products such as disinfectants, preservatives, and sanitizers. It is well-established that BAC is not genotoxic nor does it ...
AMA (American Medical Association). 1991. Drug Evaluations Annual 1991 , p. 1440. Chicago, IL.
Angrish, Michelle M., Pleil, Joachim D., Stiegel, Matthew A., Madden, Michael C., Moser, Virginia C., Herr, David W.. Taxonomic applicability of inflammatory cytokines in adverse outcome pathway (AOP) development. Journal of toxicology and environmental health. Part A, vol.79, no.4, 184-196.
Ansel, Howard C., Cabre, Gary E.. Influence of Dimethyl Sulfoxide on the Hemolytic Activity of Antimicrobial Preservatives I. Journal of pharmaceutical sciences : a publication of the American Pharmaceutical Association, vol.59, no.4, 478-481.
Bates, N., Edwards, N.. Benzalkonium chloride exposure in cats: a retrospective analysis of 245 cases reported to the Veterinary Poisons Information Service (VPIS). The Veterinary record : journal of the British Veterinary Association, vol.176, no.9, 229-229.
Baudouin, C., Labbe, A., Liang, H., Pauly, A., Brignole-Baudouin, F.. Preservatives in eyedrops: The good, the bad and the ugly. Progress in retinal and eye research, vol.29, no.4, 312-334.
Bernstein, I.Leonard. Is the use of benzalkonium chloride as a preservative for nasal formulations a safety concern? A cautionary note based on compromised mucociliary transport. The Journal of allergy and clinical immunology : official organ of American Academy of Allergy, vol.105, no.1, 39-44.
Buron, Nelly, Micheau, Olivier, Cathelin, Se´verine, Lafontaine, Pierre-Olivier, Creuzot-Garcher, Catherine, Solary, Eric. Differential Mechanisms of Conjunctival Cell Death Induction by Ultraviolet Irradiation and Benzalkonium Chloride. Investigative ophthalmology & visual science, vol.47, no.10, 4221-.
Buttar, Harpal S.. Embryotoxicity of benzalkonium chloride in vaginally treated rats. Journal of applied toxicology : JAT, vol.5, no.6, 398-401.
Chang, Caitlin, Zhang, Angela Q, Kagan, Dov B, Liu, Hong, Hutnik, Cindy ML. Mechanisms of benzalkonium chloride toxicity in a human trabecular meshwork cell line and the protective role of preservative‐free tafluprost. Clinical & experimental ophthalmology, vol.43, no.2, 164-172.
Chen, Wensheng, Li, Zhiyuan, Hu, Jiaoyue, Zhang, Zhenhao, Chen, Lelei, Chen, Yongxiong, Liu, Zuguo. Corneal Alternations Induced by Topical Application of Benzalkonium Chloride in Rabbit. PloS one, vol.6, no.10, e26103-.
Cho, Jin-Hee, Kwun, Yong-Sig, Jang, Han-Sung, Kang, Jun-Myung, Won, Yu-Sung, Yoon, He-Ro. Long-Term Use of Preservatives on Rat Nasal Respiratory Mucosa: Effects of Benzalkonium Chloride and Potassium Sorbate. The Laryngoscope, vol.110, no.2, 312-317.
Choi, S.M., Lee, B.M.. Safety and risk assessment of ceramide 3 in cosmetic products. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, vol.84, 8-17.
Jpn. J. Ophthalmol. Chou A. 13 29 1985
Christen, V., Rusconi, M., Crettaz, P., Fent, K.. Developmental neurotoxicity of different pesticides in PC-12 cells in vitro. Toxicology and applied pharmacology, vol.325, 25-36.
Int. J. Toxicol. CIR (Cosmetic Ingredient Review) 77 27 1 2008
Mol. Vis. Clouzeau C. 851 18 2012
Cochran, Roger C., Ross, John H.. A method for quantitative risk appraisal for pesticide risk assessments. Journal of toxicology and environmental health. Part A, vol.80, no.1, 1-17.
Coulston, Frederick, Drobeck, Hans P., Mielens, Zigurd E., Garvin Jr., Paul J.. Toxicology of benzalkonium chloride given orally in milk or water to rats and dogs. Toxicology and applied pharmacology, vol.3, no.5, 584-594.
Eur. Arch. Otorhinolaryngol. Cüreoğlu S. 362 259 2002 10.1007/s00405-002-0458-x
Deutschle, T., Porkert, U., Reiter, R., Keck, T., Riechelmann, H.. In vitro genotoxicity and cytotoxicity of benzalkonium chloride. Toxicology in vitro : an international journal published in association with BIBRA, vol.20, no.8, 1472-1477.
In: Appraisal of the Safety of Chemicals in Foods, Drugs, and Cosmetics Draize J. H. 1959
Regulation (EC) No 1223/2009 of the European Parliament and of the Council of 30 November 2009 on cosmetic products Off. J. Eur. Union. EC (European Commission) 2009
Ferk, F, Mis?k, M, Hoelzl, C, Uhl, M, Fuerhacker, M, Grillitsch, B, Parzefall, W, Nersesyan, A, Micieta, K, Grummt, T, Ehrlich, V, Knasm?ller, S. Benzalkonium chloride (BAC) and dimethyldioctadecyl-ammonium bromide (DDAB), two common quaternary ammonium compounds, cause genotoxic effects in mammalian and plant cells at environmentally relevant concentrations.. Mutagenesis, vol.22, no.6, 363-370.
Gardner, William P., Girard, James E.. Analysis of Common Household Cleaner-Disinfectants by Capillary Electrophoresis. Journal of chemical education, vol.77, no.10, 1335-.
Gasset, Antonio R., Ishii, Yasuo, Kaufman, Herbert E., Miller, Thomas. Cytotoxicity of Ophthalmic Preservatives. American journal of ophthalmology, vol.78, no.1, 98-105.
Clinical Toxicology of Commercial Products Gosselin R. E. 1984 5
Grant, W. M. 1986. Toxicology of the Eye , 3rd ed. 139. Springfield, IL: Charles C. Thomas Publisher.
GRIFFITH, J. Dose-response studies with chemical irritants in the albino rabbit eye as a basis for selecting optimum testing conditions for predicting hazard to the human eye. Toxicology and applied pharmacology, vol.55, no.3, 501-513.
Hall, B., Tozer, S., Safford, B., Coroama, M., Steiling, W., Leneveu-Duchemin, M.C., McNamara, C., Gibney, M.. European consumer exposure to cosmetic products, a framework for conducting population exposure assessments. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, vol.45, no.11, 2097-2108.
Hikiba, Hirohito, Watanabe, Eiko, Barrett, J. Carl, Tsutsui, Takeki. Ability of Fourteen Chemical Agents Used in Dental Practice to Induce Chromosome Aberrations in Syrian Hamster Embryo Cells. Journal of pharmacological sciences, vol.97, no.1, 146-152.
Hitosugi, M., Maruyama, K., Takatsu, A.. A case of fatal benzalkonium chloride poisoning. International journal of legal medicine, vol.111, no.5, 265-266.
Ho, Ching-Yin, Wu, Meng-Chuan, Lan, Ming-Ying, Tan, Ching-Ting, Yang, An-Hang. In Vitro Effects of Preservatives in Nasal Sprays on Human Nasal Epithelial Cells. American journal of rhinology, vol.22, no.2, 125-129.
Johnson, Neil F.. Pulmonary Toxicity of Benzalkonium Chloride. Journal of aerosol medicine and pulmonary drug delivery, vol.31, no.1, 1-17.
Toxicological profile of cosmetics ingredients. Korea Cosmetic Industry Institute (KCII). 2012
Kim, Jae Ryun, Oh, Tae Hoon, Kim, Hyun Seung. Effects of benzalkonium chloride on the ocular surface of the rabbit. Japanese journal of ophthalmology, vol.55, no.3, 283-293.
Kim, Kyu-Bong, Kim, Young Woo, Lim, Seong Kwang, Roh, Tae Hyun, Bang, Du Yeon, Choi, Seul Min, Lim, Duck Soo, Kim, Yeon Joo, Baek, Seol-Hwa, Kim, Min-Kook, Seo, Hyo-Seon, Kim, Min-Hwa, Kim, Hyung Sik, Lee, Joo Young, Kacew, Sam, Lee, Byung-Mu. Risk assessment of zinc oxide, a cosmetic ingredient used as a UV filter of sunscreens. Journal of toxicology and environmental health. Part B, Critical reviews, vol.20, no.3, 155-182.
Kim, M.J., Kwack, S.J., Lim, S.K., Kim, Y.J., Roh, T.H., Choi, S.M., Kim, H.S., Lee, B.M.. Toxicological evaluation of isopropylparaben and isobutylparaben mixture in Sprague-Dawley rats following 28 days of dermal exposure. Regulatory toxicology and pharmacology : RTP, vol.73, no.2, 544-551.
KUBOYAMA, Yasumasa, SUZUKI, Kazuo, HARA, Takuji. Nasal lesions induced by intranasal administration of benzalkonium chloride in rats.. The Journal of toxicological sciences, vol.22, no.2, 153-160.
Labbé, Antoine, Pauly, Aude, Liang, Hong, Brignole-Baudouin, Françoise, Martin, Chantal, Warnet, Jean-Michel, Baudouin, Christophe. Comparison of Toxicological Profiles of Benzalkonium Chloride and Polyquaternium-1: An Experimental Study. Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics, vol.22, no.4, 267-278.
Lavorgna, M., Russo, C., D'Abrosca, B., Parrella, A., Isidori, M.. Toxicity and genotoxicity of the quaternary ammonium compound benzalkonium chloride (BAC) using Daphnia magna and Ceriodaphnia dubia as model systems. Environmental pollution, vol.210, 34-39.
LEE, Sang S., HONG, Dong K., JEONG, Nam J., LEE, Jeung H., CHOI, Yun‐Seok, LEE, Ai‐Young, LEE, Cheol‐Heon, KIM, Kea J., PARK, Hae Y., YANG, Jun‐Mo, LEE, Ga‐Young, LEE, Joon, EUN, Hee C., MOON, Kee‐Chan, SEO, Seong J., HONG, Chang K., LEE, Sang W., CHOI, Hae Y., LEE, Jun Y.. Multicenter study of preservative sensitivity in patients with suspected cosmetic contact dermatitis in Korea. The Journal of dermatology, vol.39, no.8, 677-681.
Liang, Hong, Baudouin, Christophe, Labbe, Antoine, Riancho, Luisa, Brignole-Baudouin, Françoise. Conjunctiva-Associated Lymphoid Tissue (CALT) Reactions to Antiglaucoma Prostaglandins with or without BAK-Preservative in Rabbit Acute Toxicity Study. PloS one, vol.7, no.3, e33913-.
2 Final Report on the Safety Assessment of Benzalkonium Chloride. Journal of the American College of Toxicology, vol.8, no.4, 589-625.
Loretz, L.J., Api, A.M., Babcock, L., Barraj, L.M., Burdick, J., Cater, K.C., Jarrett, G., Mann, S., Pan, Y.H.L., Re, T.A., Renskers, K.J., Scrafford, C.G.. Exposure data for cosmetic products: Facial cleanser, hair conditioner, and eye shadow. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, vol.46, no.5, 1516-1524.
Loretz, L.J., Api, A.M., Barraj, L.M., Burdick, J., Dressler, W.E., Gettings, S.D., Han Hsu, H., Pan, Y.H.L., Re, T.A., Renskers, K.J., Rothenstein, A., Scrafford, C.G., Sewall, C.. Exposure data for cosmetic products: lipstick, body lotion, and face cream. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, vol.43, no.2, 279-291.
Lovely, T.J., Levin, D.E., Klekowski, E.. Light-induced genetic toxicity of thimerosal and benzalkonium chloride in commercial contact lens solutions. Mutation research. Genetic toxicology testing, vol.101, no.1, 11-18.
Marple, Bradley, Roland, Peter, Benninger, Michael. Safety review of benzalkonium chloride used as a preservative in intranasal solutions: an overview of conflicting data and opinions. Otolaryngology-head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery, vol.130, no.1, 131-141.
The regulation on safety standards and others of cosmetics MFDS (The Ministry of Food and Drug Safety) 2014
O’Neil, M., A. Smith, and P. Heckelman. 2001. The Merck Index: An Encyclopedia of Chemicals, Drugs, and Biologicals , 13th ed. 1060. Merck & Co., Whitehouse Station, NJ.
Osol, A. (ed.). 1980. Remington’s Pharmaceutical Sciences . 16th. Easton, Pennsylvania: Mack Publishing Co. 1100.
Parrella, A., Lavorgna, M., Criscuolo, E., Russo, C., Isidori, M.. Eco-genotoxicity of six anticancer drugs using comet assay in daphnids. Journal of hazardous materials, vol.286, 573-580.
Crit. Rev. Oncogol. Patarca R. 255 11 2000
Pisella, Pierre-Jean, Fillacier, Kathleen, Elena, Pierre-Paul, Debbasch, Caroline, Baudouin, Christophe. Comparison of the Effects of Preserved and Unpreserved Formulations of Timolol on the Ocular Surface of Albino Rabbits. Ophthalmic research, vol.32, no.1, 3-8.
Pleil, Joachim D., Sobus, Jon R.. Estimating central tendency from a single spot measure: A closed-form solution for lognormally distributed biomarker data for risk assessment at the individual level. Journal of toxicology and environmental health. Part A, vol.79, no.18, 837-847.
Rathore, Mahendra Singh, Majumdar, Dipak K.. Effect of formulation factors on in vitro transcorneal permeation of gatifloxacin from aqueous drops. AAPS PharmSciTech, vol.7, no.3, E12-E17.
Romanowski, Eric G., Mah, Francis S., Kowalski, Regis P., Yates, Kathleen A., Gordon, Y. Jerold. Benzalkonium Chloride Enhances the Antibacterial Efficacy of Gatifloxacin in an Experimental Rabbit Model of Intrastromal Keratitis. Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics, vol.24, no.4, 380-384.
Handbook of Pharmaceutical Excipients Rowe R. C. 2009 6
Sarkar, Joy, Chaudhary, Shweta, Namavari, Abed, Ozturk, Okan, Chang, Jin-Hong, Yco, Lisette, Sonawane, Snehal, Khanolkar, Vishakha, Hallak, Joelle, Jain, Sandeep. Corneal Neurotoxicity Due to Topical Benzalkonium Chloride. Investigative ophthalmology & visual science, vol.53, no.4, 1792-.
Reports of the Scientific Committee on Cosmetology (ninth series) SCC (Scientific Committee on Cosmetology) 2000
Serrano, Helena C., Köbel, Melanie, Palma-Oliveira, José, Pinho, Pedro, Branquinho, Cristina. Mapping Exposure to Multi-Pollutants Using Environmental Biomonitors-A Multi-Exposure Index. Journal of toxicology and environmental health. Part A, vol.80, no.13, 710-718.
Shirasu, Y., Moriya, M., Kato, K., Furuhashi, A., Kada, T.. Mutagenicity screening of pesticides in the microbial system. Mutation research. Genetic toxicology testing, vol.40, no.1, 19-30.
Son, Ji Yeon, Kang, Yoon Jong, Kim, Kyeong Seok, Kim, Tae Hyung, Lim, Sung Kwang, Lim, Hyun Jung, Jeong, Tae Cheon, Choi, Dal Woong, Chung, Kyu Hyuck, Lee, Byung Mu, Kim, Hyung Sik. Evaluation of Renal Toxicity by Combination Exposure to Melamine and Cyanuric Acid in Male Sprague-Dawley Rats. Toxicological research, vol.30, no.2, 99-107.
Acta Pharmacol. Toxicol. Stenbäck F. 41 41 1977 10.1111/j.1600-0773.1977.tb02152.x
Stiegel, Matthew A., Pleil, Joachim D., Sobus, Jon R., Stevens, Tina, Madden, Michael C.. Linking physiological parameters to perturbations in the human exposome: Environmental exposures modify blood pressure and lung function via inflammatory cytokine pathway. Journal of toxicology and environmental health. Part A, vol.80, no.9, 485-501.
Thorsteinsson, T, Loftsson, T, Masson, M. Soft antibacterial agents.. Current medicinal chemistry, vol.10, no.13, 1129-1136.
Clustering of quaternary ammonium compounds U.S. EPA (U.S. Environmental Protection Agency) 1988
Reregistration Eligibility Decision (RED) document for Alkyl Dimethyl Benzyl Ammonium Chloride (ADBAC). EPA739-R-06-009 U.S. EPA (U.S. Environmental Protection Agency) 2006
The Division of Over-the-Counter Drug Evaluation Ingredient Status Report U.S. FDA (Food and Drug Administration) 1984
Cosmetic product formulation data U.S. FDA (Food and Drug Administration) 1986
Wade, A., and P. J. Weller. (ed). 1994. A handbook of pharmaceutical excipients . 2nd ed. London: The pharmaceutical press. 27-31.
Wallace, M. Ariel Geer, Kormos, Tzipporah M., Pleil, Joachim D.. Blood-borne biomarkers and bioindicators for linking exposure to health effects in environmental health science. Journal of toxicology and environmental health. Part B, Critical reviews, vol.19, no.8, 380-409.
Wentworth, Ashley B., Yiannias, James A., Davis, Mark D.P., Killian, Jill M.. Benzalkonium Chloride : A Known Irritant and Novel Allergen. Dermatitis : contact, atopic, occupational, drug, vol.27, no.1, 14-20.
Mol. Vis. Wu H. 3364 17 2011
Xiong, Cuiju, Chen, Dong, Liu, Jingbo, Liu, Bingqian, Li, Naiyang, Zhou, Yang, Liang, Xuanwei, Ma, Ping, Ye, Chengtian, Ge, Jian, Wang, Zhichong. A Rabbit Dry Eye Model Induced by Topical Medication of a Preservative Benzalkonium Chloride. Investigative ophthalmology & visual science, vol.49, no.5, 1850-.
Xue, Yuying, Hieda, Yoko, Kimura, Kojiro, Nishiyama, Takashi, Adachi, Toshinori. Sensitive determination of benzalkonium chloride in blood and tissues using high-performance liquid chromatography with solid-phase extraction. Legal medicine, vol.4, no.4, 232-238.
Xue, Yuying, Hieda, Yoko, Saito, Yoji, Nomura, Takeshi, Fujihara, Junko, Takayama, Koji, Kimura, Kojiro, Takeshita, Haruo. Distribution and disposition of benzalkonium chloride following various routes of administration in rats. Toxicology letters, vol.148, no.1, 113-123.
Ye, Juan, Wu, Han, Zhang, Huina, Wu, Yihua, Yang, Jun, Jin, Xiuming, Shi, Xin. Role of benzalkonium chloride in DNA strand breaks in human corneal epithelial cells. Graefe’s archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv für klinische und experimentelle Ophthalmologie, vol.249, no.11, 1681-1687.
Zhou, Y., Liu, Q., Zhou, T., Lin, Z., Zong, R., Liu, Z., Sun, F., Shao, Y., Liu, X., Ma, J.x., Liu, Z.. Modulation of the canonical Wnt pathway by Benzalkonium Chloride in corneal epithelium. Experimental eye research, vol.93, no.4, 355-362.
*원문 PDF 파일 및 링크정보가 존재하지 않을 경우 KISTI DDS 시스템에서 제공하는 원문복사서비스를 사용할 수 있습니다.
※ AI-Helper는 부적절한 답변을 할 수 있습니다.